Emergency Medicine
Long-term follow-up of RCT: Decompressive craniectomy vs. standard medical care in patients with traumatic intracranial hypertension.
10 Jun, 2022 | 12:45h | UTCEvaluation of Outcomes Among Patients With Traumatic Intracranial Hypertension Treated With Decompressive Craniectomy vs Standard Medical Care at 24 Months: A Secondary Analysis of the RESCUEicp Randomized Clinical Trial – JAMA Neurology (free for a limited period)
Original Study: Trial of Decompressive Craniectomy for Traumatic Intracranial Hypertension – New England Journal of Medicine
Related:
The Current Status of Decompressive Craniectomy in Traumatic Brain Injury – Current Trauma Reports
Commentary on Twitter
In this study, at 24 months, patients with posttraumatic refractory intracranial hypertension managed with a decompressive craniectomy had a sustained mortality reduction and higher rates of vegetative state, severe disability, and moderate disability. https://t.co/I8GqG885jh
— JAMA Neurology (@JAMANeuro) June 9, 2022
Study Commentary: Traumatic hemothorax: pigtail vs. chest tube.
10 Jun, 2022 | 10:57h | UTCTraumatic Hemothorax: Pigtail vs Chest Tube – RebelEM
Original Study: The small (14 Fr) percutaneous catheter (P-CAT) versus large (28–32 Fr) open chest tube for traumatic hemothorax: A multicenter randomized clinical trial – Trauma and Acute Care Surgery (link to abstract – $ for full-text)
Drug-related hypersensitivity reactions leading to emergency department: original data and systematic review.
10 Jun, 2022 | 10:46h | UTC
M-A: Association of high-volume centers with survival outcomes among patients with nontraumatic out-of-hospital cardiac arrest.
10 Jun, 2022 | 10:42h | UTC
Commentary on Twitter
This systematic review and meta-analysis found that care at high-volume centers was associated with improved survival, but not neurological outcomes, in patients with out of hospital cardiac arrest #OHCA. https://t.co/5jzhqX1d7I
— JAMA Network Open (@JAMANetworkOpen) May 31, 2022
Systematic Review: Evidence-based perioperative diagnosis and management of pulmonary embolism.
9 Jun, 2022 | 10:34h | UTC
Statement on initial antimicrobial treatment of sepsis.
8 Jun, 2022 | 11:17h | UTCStatement on initial antimicrobial treatment of sepsis – Faculty of Intensive Care Medicine
Commentary on Twitter
🚨Statement on initial antimicrobial treatment of sepsis🚨
Full statement and documents available➡️ https://t.co/jWexX1VDDd @AoMRC pic.twitter.com/kQdJrZ2hOA
— FICMNews (@FICMNews) June 4, 2022
M-A: Efficacy and harms of tocilizumab for the treatment of COVID-19 patients.
8 Jun, 2022 | 11:06h | UTC
M-A: Efficacy and safety of intensified versus standard prophylactic anticoagulation therapy in patients with Covid-19.
8 Jun, 2022 | 11:09h | UTCRelated:
Anticoagulants for people hospitalised with COVID‐19 – Cochrane Library
Commentary on Twitter
🆕💥💥Systematic review & meta-analysis @OFIDJournal Intensified anticoagulation has NO effect on mortality among hospitalised #COVID19 & ⬆️bleeding
Possible signal of mortality reduction for non-ICU patients although with low precision& high heterogeneity https://t.co/OqLYScxK53— Antibiotic Steward Bassam Ghanem 🅱️C🆔🅿️🌟 (@ABsteward) June 7, 2022
Review: Timing of vasoactive agents and corticosteroid initiation in septic shock.
8 Jun, 2022 | 10:53h | UTCTiming of vasoactive agents and corticosteroid initiation in septic shock – Annals of Intensive Care
Prediction of fluid responsiveness. What’s new?
7 Jun, 2022 | 11:35h | UTCPrediction of fluid responsiveness. What’s new? – Annals of Intensive Care
ANMCO position paper on antithrombotic treatment of patients with atrial fibrillation undergoing intracoronary stenting and/or acute coronary syndromes.
7 Jun, 2022 | 11:32h | UTC
Review: Dyspnea and cough in a lung transplant recipient.
7 Jun, 2022 | 11:16h | UTCDyspnea and cough in a lung transplant recipient – Cleveland Clinic Journal of Medicine
Oncologic emergencies and urgencies: A comprehensive review.
6 Jun, 2022 | 12:06h | UTCOncologic emergencies and urgencies: A comprehensive review – CA: A Cancer Journal for Clinicians
Commentary on Twitter
🎯Just in time for #ASCO22 | Oncologic emergencies and urgencies: A comprehensive review https://t.co/HyZmI37tr5 @BEGouldRothberg @YaleCancer @KeithDelman
CC: @OncoAlert pic.twitter.com/57tqiLXijN— CA: A Cancer Journal for Clinicians (@CACancerJournal) June 2, 2022
Special Issue: Covid-19 Infection.
3 Jun, 2022 | 12:04h | UTCHomepage: Covid-19 Infection – Infectious Disease Clinics of North America
Editorial: COVID-19: Where We Are, Where We Need to Be
COVID-19 Pathogenesis and Clinical Manifestations
SARS-CoV-2 Transmission and Prevention in the Era of the Delta Variant
Laboratory Diagnosis for SARS-CoV-2 Infection
Pharmacologic Treatment and Management of Coronavirus Disease 2019
COVID-19 in the Critically Ill Patient
Postacute Sequelae of Severe Acute Respiratory Syndrome Coronavirus 2 Infection
COVID-19 in the Immunocompromised Host, Including People with Human Immunodeficiency Virus
Severe Acute Respiratory Syndrome Coronavirus 2 Infections in Children
Guidelines for management of Clostridioides (Clostridium) difficile infection.
3 Jun, 2022 | 11:28h | UTC
Guidelines on stroke in women: management of menopause, pregnancy and postpartum.
2 Jun, 2022 | 11:27h | UTC
NIH Updated Guideline: Antithrombotic therapy in patients with COVID-19.
2 Jun, 2022 | 11:25h | UTCAntithrombotic Therapy in Patients With COVID-19 – National Institutes of Health
Retrospective Cohort Study: Racial and ethnic discrepancy in pulse oximetry and delayed identification of treatment eligibility among patients with COVID-19.
1 Jun, 2022 | 11:58h | UTCEditorial: Racial and Ethnic Bias in Pulse Oximetry and Clinical Outcomes
Related:
Racial Bias in Pulse Oximetry Measurement – New England Journal of Medicine
FDA issues alert on ‘limitations’ of pulse oximeters, without explicit mention of racial bias – STAT
Pulse Oximeter Accuracy and Limitations: FDA Safety Communication – U.S. Food & Drug Administration
Commentary on Twitter
This cohort study found overestimation of arterial oxygen saturation levels by pulse oximetry occurred in Asian, Black, and Hispanic patients with #COVID19 and delayed care compared with White patients. https://t.co/ptOVwuUewr @AshFawzyMD @GoldenSherita @AmandaBradke @BTGaribaldi
— JAMA Internal Medicine (@JAMAInternalMed) May 31, 2022
Understanding base excess (BE): merits and pitfalls.
1 Jun, 2022 | 11:33h | UTCUnderstanding base excess (BE): merits and pitfalls – Intensive Care Medicine (if the link is paywalled, try this one)
Commentary on Twitter
Understanding base excess
🧪 valuable quantitative estimate of metabolic acid-base derangements, but not info on underlying mechanisms
🧪 standard BE composite marker: several components contribute; interpretation of isolated value very difficult#FOAMcc
🖇️https://t.co/T8pcVRrTgR pic.twitter.com/6TEFsFTJR1— Intensive Care Medicine (@yourICM) May 31, 2022
Brief Review: Administration of vasopressors through peripheral venous catheters.
1 Jun, 2022 | 11:00h | UTCRelated:
Complication of vasopressor infusion through peripheral venous catheter: A systematic review and meta-analysis – The American Journal of Emergency Medicine (link to abstract – $ for full-text)
An update on peripheral vasopressors – First10EM
Systematic Review: Magnesium sulfate for acute exacerbations of chronic obstructive pulmonary disease.
31 May, 2022 | 11:16h | UTC
Commentary on Twitter
Is magnesium sulfate effective for #COPD flare‐ups? @CochraneAirways systematic review evaluates the evidence from 11 studies. ''Magnesium infusion may ⬇️ hospital admissions, shorten length of hospital stay & improve breathlessness compared to placebo' https://t.co/ZUPVrcdRzk pic.twitter.com/IxBGlnU6FZ
— The Cochrane Library (@CochraneLibrary) May 30, 2022
Delirium: How can we protect our patients? Detection and treatment strategies.
31 May, 2022 | 11:10h | UTCRelated:
Less pharmacotherapy is more in delirium – Intensive Care Medicine
Effectiveness of Bundle Interventions on ICU Delirium: A Meta-Analysis – Critical Care Medicine
Hypoxia in the ED setting: systematic approach and management.
31 May, 2022 | 10:56h | UTCHypoxia in the ED Setting: Systematic Approach and Management – emDocs
RCT: Fast multiplex bacterial PCR of bronchoalveolar lavage for antibiotic stewardship in hospitalized patients with pneumonia at risk of Gram-negative bacterial infection.
31 May, 2022 | 10:55h | UTCFast multiplex bacterial PCR of bronchoalveolar lavage for antibiotic stewardship in hospitalised patients with pneumonia at risk of Gram-negative bacterial infection (Flagship II): a multicentre, randomised controlled trial – The Lancet Respiratory Medicine (link to abstract – $ for full-text)
Commentary on Twitter
NEW Research—Multiplex bacterial PCR examination of bronchoalveolar lavage decreases duration of inappropriate antibiotic therapy of pts admitted to hospital w/ pneumonia & at risk of Gram-negative rod infection
From @AndreiMDarie & colleagues https://t.co/jnBak5SkJo pic.twitter.com/Py28aFqMw9
— The Lancet Respiratory Medicine (@LancetRespirMed) May 25, 2022
Consensus: nephrotoxic potential of 167 drugs in adult critically ill patients.
30 May, 2022 | 11:50h | UTCConsensus Obtained for the Nephrotoxic Potential of 167 Drugs in Adult Critically Ill Patients Using a Modified Delphi Method – Drug Safety (if the link is paywalled, try this one)