Emergency Medicine
Cohort Study | Severe lymphopenia may predict worse outcomes in hospitalized patients with pneumococcal CAP
31 Jan, 2023 | 13:52h | UTCImpact of severe lymphopenia on the early prediction of clinical outcome in hospitalized patients with pneumococcal community-acquired pneumonia – Infection (if the link is paywalled, try this one in PMC)
Podcast | Acute exacerbations of COPD
31 Jan, 2023 | 13:48h | UTC#378 Acute Exacerbations of COPD (AECOPD) – The Curbsiders
Guideline | Management of adult renal trauma
30 Jan, 2023 | 01:20h | UTCRelated:
Kidney and uro-trauma: WSES-AAST guidelines – World Journal of Emergency Surgery
Urotrauma: AUA Guideline – The Journal of Urology
Urological Trauma – European Association of Urology
Renal trauma: the current best practice – Therapeutic Advances in Urology
RCT | Early extracorporeal CPR did not improve outcomes in patients with refractory out-of-hospital cardiac arrest
30 Jan, 2023 | 01:18h | UTCEarly Extracorporeal CPR for Refractory Out-of-Hospital Cardiac Arrest – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: Early Extracorporeal CPR for Out-of-Hospital Cardiac Arrest – American College of Cardiology
Commentary on Twitter
In a randomized trial, patients with out-of-hospital cardiac arrest who received extracorporeal CPR and those who received conventional CPR had similar results for survival and favorable neurologic outcomes. https://t.co/Irw8nrV8AA pic.twitter.com/lOPsBzhP3O
— NEJM (@NEJM) January 27, 2023
RCT | Simple aspiration versus drainage for complete pneumothorax
30 Jan, 2023 | 00:40h | UTCSimple Aspiration Versus Drainage for Complete Pneumothorax: A Randomized Non-Inferiority Trial – Am J Respir Crit Care Med (link to abstract – $ for full-text)
Perspective | Is it time to retire the diagnosis “hypertensive emergency”?
27 Jan, 2023 | 12:26h | UTC
CT imaging of the larynx for may be a tool for the diagnosis of vocal cord dysfunction
27 Jan, 2023 | 12:13h | UTCComputed Tomography Imaging of the Larynx for Diagnosis of Vocal Cord Dysfunction – NEJM Evidence (link to abstract – $ for full-text)
Commentary on Twitter
Original Article: “Computed Tomography Imaging of the Larynx for Diagnosis of Vocal Cord Dysfunction,” by Philip G. Bardin, PhD, et al. https://t.co/b4YWBTeQA9#Asthma #PulmTwitter #MedTwitter #ClinicalTrials @PhilBardin @DebbiePhyland @PaulLeongMD @MonashHealth pic.twitter.com/wgmstsn0wG
— NEJM Evidence (@NEJMEvidence) January 13, 2023
Review | The blood–brain barrier and optimization of antibiotics for the treatment of CNS infections in adults
27 Jan, 2023 | 11:55h | UTC
Review | Spotlight on vaccine-induced thrombosis and thrombocytopenia (VITT)
26 Jan, 2023 | 12:46h | UTCSpotlight on vaccine-induced thrombosis and thrombocytopenia (VITT) – Blood
Cohort study | Endovascular balloon occlusion of the aorta may be an alternative to resuscitative thoracotomy in traumatic hemorrhagic shock
26 Jan, 2023 | 12:18h | UTCZone 1 Endovascular Balloon Occlusion of the Aorta vs Resuscitative Thoracotomy for Patient Resuscitation After Severe Hemorrhagic Shock – JAMA Surgery (link to abstract – $ for full-text)
Commentary on Twitter
Cohort study using the @traumadoctors AORTA registry suggests that zone 1 endovascular balloon occlusion of the aorta is an effective alternative to resuscitative thoracotomy with similar or better survival rates. https://t.co/QqyXRlPtOb #Research #REBOA
— JAMA Surgery (@JAMASurgery) December 22, 2022
Systematic review to evaluate algorithms for REBOA use in trauma and identify a consensus for patient selection
26 Jan, 2023 | 12:13h | UTCRelated: Zone 1 Endovascular Balloon Occlusion of the Aorta vs Resuscitative Thoracotomy for Patient Resuscitation After Severe Hemorrhagic Shock – JAMA Surgery (link to abstract – $ for full-text)
Cardiogenic Shock | Emergency department-focused management
25 Jan, 2023 | 11:21h | UTCCardiogenic Shock: Emergency Department-Focused Management – emDocs
Related: The medical treatment of cardiogenic shock – Journal of Intensive Medicine
AHA Statement | Surgical management and mechanical circulatory support in high-risk pulmonary embolisms
24 Jan, 2023 | 14:40h | UTCNews Release: New statement suggests more patients may benefit from surgery for pulmonary embolism – American Heart Association
Commentary from one of the authors on Twitter (thread – click for more)
https://twitter.com/jaygirimd/status/1617587286568472581
RCT | Outcomes not different with early restrictive vs. liberal fluid management in sepsis-induced hypotension
24 Jan, 2023 | 14:38h | UTCEarly Restrictive or Liberal Fluid Management for Sepsis-Induced Hypotension – New England Journal of Medicine (link to abstract – $ for full-text)
News Release: Study comparing early interventions for sepsis shows patients have identical outcomes – Vanderbilt University Medical Center
Commentary on Twitter
This trial comparing treatment strategies that emphasized the use of vasopressors or intravenous fluids for early treatment of sepsis-induced hypotension showed no difference in 90-day mortality before discharge home. #SCCM2023 https://t.co/aIymxmBENE pic.twitter.com/18lFQLMBfA
— NEJM (@NEJM) January 22, 2023
Retrospective Study | Serial troponin-T and long-term outcomes in suspected acute coronary syndrome
24 Jan, 2023 | 14:09h | UTC
Commentary on Twitter
Serial troponin-T and long-term outcomes in suspected acute coronary syndrome https://t.co/cTm1fJTuKl#AHA22 @ehj_ed @rladeiraslopes pic.twitter.com/0p8cO8zhzi
— European Society of Cardiology Journals (@ESC_Journals) November 7, 2022
Perspective | The top 11 priorities to improve trauma outcomes, from system to patient level
24 Jan, 2023 | 14:06h | UTC
Review | Wellens syndrome: an important consideration in patients with chest pain
23 Jan, 2023 | 13:26h | UTCWellens syndrome: An important consideration in patients with chest pain – JAAPA
Commentary: Wellens Syndrome Important to Consider if Chest Pain: Key Points – American College of Cardiology
AHA Scientific Statement | Diagnosis, workup, risk reduction of transient ischemic attack in the ED setting
20 Jan, 2023 | 14:56h | UTCNews Release: Stroke symptoms, even if they disappear within an hour, need emergency assessment – American Heart Association
Guideline | Diagnosis and treatment of pleural effusion
20 Jan, 2023 | 14:55h | UTCRelated:
Update on Management of Pleural Disease – Current Pulmonology Reports
Pleural Effusion in Adults—Etiology, Diagnosis, and Treatment – Deutsches Ärzteblatt international
Evaluation of the patient with pleural effusion – Canadian Medical Association Journal
State-of-the-art: Radiological investigation of pleural disease – Respiratory Medicine
RCT | Aspirin noninferior to low-molecular-weight heparin for thromboprophylaxis after a fracture
19 Jan, 2023 | 14:30h | UTCAspirin or Low-Molecular-Weight Heparin for Thromboprophylaxis after a Fracture – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: PREVENT CLOT Supports Aspirin for VTE Prevention in Trauma Fractures – TCTMD
RCT | Early high-flow nasal oxygen did not improve outcomes in hospitalized children with acute hypoxemic respiratory failure
18 Jan, 2023 | 14:34h | UTCEffect of Early High-Flow Nasal Oxygen vs Standard Oxygen Therapy on Length of Hospital Stay in Hospitalized Children With Acute Hypoxemic Respiratory Failure: The PARIS-2 Randomized Clinical Trial – JAMA (free for a limited period)
See also: Visual Abstract
RCT | Effect of 5% EMLA cream on postoperative sore throat in adults following general endotracheal anesthesia
17 Jan, 2023 | 13:05h | UTCEffect of 5% EMLA Cream on Postoperative Sore Throat in Adults Following General Endotracheal Anesthesia: A Randomized Placebo-Controlled Study – Anesthesia & Analgesia (link to abstract – $ for full-text)
M-A | Efficacy and safety of corticosteroids in cardiac arrest
17 Jan, 2023 | 13:03h | UTC
Review | Current perspectives on maternity critical care
17 Jan, 2023 | 13:00h | UTCCurrent perspectives on maternity critical care – Anaesthesia
RCT | Fluvoxamine no better than placebo in outpatients with mild to moderate COVID-19
15 Jan, 2023 | 20:37h | UTCEditorial: Lack of Benefit of Fluvoxamine for COVID-19 – JAMA
Author Interview: Fluvoxamine vs Placebo and Time to Sustained Recovery From Mild or Moderate COVID-19 – JAMA
Commentary: Trial finds that fluvoxamine doesn’t speed COVID recovery – CIDRAP
Commentary on Twitter
Among outpatients with mild to moderate #COVID19, treatment with 50 mg of fluvoxamine twice daily for 10 days, compared with placebo, did not improve time to sustained recovery. https://t.co/4QgBssqFSU pic.twitter.com/RMZ6mqlx6u
— JAMA (@JAMA_current) January 12, 2023