Critical Care
Cohort Study | Excess oxygen administration during surgery is linked to an increased risk of postoperative organ injury.
1 Dec, 2022 | 13:55h | UTCEditorial: Oxygen administration during general anaesthesia for surgery – The BMJ
News Release: Excess oxygen during surgery linked to higher risk of organ damage – BMJ Newsroom
Commentary: Perioperative oxygen administration: finding the sweet spot – The BMJ
Cohort Study | 1 in 3 patients with hemodynamically unstable pelvic fractures die.
1 Dec, 2022 | 13:54h | UTCAssociation Between Hemorrhage Control Interventions and Mortality in US Trauma Patients With Hemodynamically Unstable Pelvic Fractures – JAMA Surgery (free for a limited period)
Invited Commentary: Nationwide Variation of Care for Patients With Bleeding Pelvic Fracture—An Opportunity to Rescue Better? – JAMA Surgery (free for a limited period)
Author Interview: Hemorrhage Control Interventions and Mortality in Trauma Patients With Hemodynamically Unstable Pelvic Fractures – JAMA
Commentary on Twitter
Study by @AZTraumaCats comparing pelvic fracture hemorrhage control interventions, >1/3 of pts died despite advancements in hemorrhage control strategies. Only pelvic angioembolization was assoc'd w reduction in mortality. https://t.co/j8ujPmr1vO @TopKniFe_B @TanyaAnand8
— JAMA Surgery (@JAMASurgery) November 30, 2022
Virtual and augmented reality in critical care medicine: the patient’s, clinician’s, and researcher’s perspective.
30 Nov, 2022 | 13:37h | UTC
Cohort Study | Impact of BMI on outcomes in respiratory ECMO.
30 Nov, 2022 | 13:35h | UTCImpact of BMI on outcomes in respiratory ECMO: an ELSO registry study – Intensive Care Medicine
Near Hanging: evaluation and management.
29 Nov, 2022 | 14:14h | UTCNear Hanging: evaluation and management – Chest (PDF)
Evidence-based approach to the surgical management of acute pancreatitis.
29 Nov, 2022 | 14:10h | UTCEvidence-Based Approach to the Surgical Management of Acute Pancreatitis – The Surgery Journal
Related:
Aggressive or Moderate Fluid Resuscitation in Acute Pancreatitis – New England Journal of Medicine (link to abstract – $ for full-text)
Acute Pancreatitis: Diagnosis and Treatment – Drugs
Evidence-Based Disposition of Acute Pancreatitis – emDocs
Pancreatitis – National Institute for Health and Care Excellence
Review | Thrombolysis in cardiac arrest.
29 Nov, 2022 | 14:08h | UTCThrombolysis in Cardiac Arrest – emDocs
Cohort Study | Trends and risk factors for venous thromboembolism among hospitalized medical patients.
29 Nov, 2022 | 14:04h | UTC
Commentary on Twitter
1.2% of hospitalized patients developed a hospital-associated venous thromboembolism (HA-VTE), slightly increasing from 2013-2016 (1.1-1.6%). 78% happened after discharge; HA-VTE were linked to higher risk of readmission and death. @KPDOR https://t.co/cB8VhY7k7X #OAResearch
— JAMA Network Open (@JAMANetworkOpen) November 21, 2022
RCT | Rezafungin vs. caspofungin for treatment of candidaemia and invasive candidiasis.
29 Nov, 2022 | 13:54h | UTCRezafungin versus caspofungin for treatment of candidaemia and invasive candidiasis (ReSTORE): a multicentre, double-blind, double-dummy, randomised phase 3 trial – The Lancet (link to abstract – $ for full-text)
Review | Infectious complications of abortion.
29 Nov, 2022 | 13:56h | UTCInfectious Complications of Abortion – Open Forum Infectious Diseases
Brief Review | Tailoring treatments to older people in intensive care. A way forward.
29 Nov, 2022 | 13:51h | UTCTailoring treatments to older people in intensive care. A way forward – Intensive Care Medicine
Commentary on Twitter
Treating older pts in #ICU?
➡️ subgroup growing fast(est)
➡️ outcomes not so poor, but appropriateness context-specific
➡️clusters w similar clinical/prognostic profiles described: most appropriate interventions for them?
📎 https://t.co/iVp5A1gqoQOn
📎 https://t.co/WzN4L4LNt7 pic.twitter.com/2pcAEjmgmy— Intensive Care Medicine (@yourICM) November 11, 2022
Brief Review | When the kidneys hurt, the other organs suffer.
29 Nov, 2022 | 13:50h | UTCWhen the kidneys hurt, the other organs suffer – Intensive Care Medicine (if the link is paywalled, try this one)
Commentary on Twitter
When kidneys hurt, remote organs also suffer, likely contributing to associated mortality/morbidity…
Review focused on most documented/relevant interactions between #AKI &
➡️ immune system
➡️ heart
➡️ lung
➡️ gut
➡️ brain
➡️ liver#FOAMcc on @yourICM
📎 https://t.co/XJXNt5RCBc pic.twitter.com/Cb5eevD97u— Intensive Care Medicine (@yourICM) November 23, 2022
Consensus Paper | Prevention of alcohol withdrawal syndrome in the surgical ICU.
27 Nov, 2022 | 22:22h | UTC
M-A | Higher blood pressure vs. normotension targets to prevent acute kidney injury.
27 Nov, 2022 | 22:19h | UTC
2ry analysis of a RCT | Decongestion with acetazolamide in acute heart failure across the spectrum of left ventricular EF.
25 Nov, 2022 | 12:45h | UTCOriginal Study: RCT | Acetazolamide resulted in faster decongestion in patients with acute decompensated heart failure with volume overload.
Commentary on Twitter
#OriginalResearch simpub #AHA2022 #CIRCAHA22: Acetazolamide added to loop diuretics ⬆️ likelihood of successful decongestion similarily in patients with HFrEF, HFmrEF and HFpEF. Data from the #ADVOR trial. @PieterMartensMD @WilfriedMullens #AHAJournals https://t.co/MkISN2H1vA pic.twitter.com/qFjCKdRaF6
— Circulation (@CircAHA) November 6, 2022
Brief Review | Lung-protective sedation: moving toward a new paradigm of precision sedation.
25 Nov, 2022 | 12:32h | UTCLung-protective sedation: moving toward a new paradigm of precision sedation – Intensive Care Medicine (if the link is paywalled, try this one)
Commentary on Twitter
Lung-protective sedation? Let's recognize link between optimizing MV, sedation, lung injury
🎯 improved monitoring tools & determination of safe levels of effort/dyssynchrony
🎯 impact of specific agents on effort/dyssynchrony
🎯 individualize targets
🖇️ https://t.co/pLuksEEiN5 pic.twitter.com/nkw7tY15Bi— Intensive Care Medicine (@yourICM) October 14, 2022
Brief Review | Extubation in neurocritical care patients: lesson learned.
25 Nov, 2022 | 12:31h | UTCExtubation in neurocritical care patients: lesson learned – Intensive Care Medicine
Commentary on Twitter
Extubation in neuro #ICU
🧠 assess neuro function stability
🧠 perform if minimal level of consciousness, upper airway secure, negative fluid balance
📃 elaborate multi-disciplinary local protocols, selecting criteria according to resources/expertise
🖇️ https://t.co/5tvpdkHcar pic.twitter.com/DAdCKwkHng— Intensive Care Medicine (@yourICM) October 17, 2022
Review | Exertional heat stroke: pathophysiology and risk factors.
25 Nov, 2022 | 12:19h | UTCExertional heat stroke: pathophysiology and risk factors – BMJ Medicine
Related:
Classic and exertional heatstroke – Nature Reviews Disease Primers
Treatment and Prevention of Heat-Related Illness – New England Journal of Medicine
Commentary on Twitter
🆕 Review: Exertional heat #stroke ▶️ https://t.co/nJwjDaxxiD@olaitano#MedTwitter pic.twitter.com/eSIOPcjk1E
— BMJMedicine (@BMJMedicine) November 11, 2022
Review | Care of the seriously ill patient with SARS-CoV-2.
24 Nov, 2022 | 13:26h | UTCCare of the Seriously Ill Patient with SARS-CoV-2 – Medical Clinics of North America
SR | Surgical decompression for malignant cerebral edema after ischemic stroke.
24 Nov, 2022 | 13:25h | UTCSurgical decompression for malignant cerebral oedema after ischaemic stroke – Cochrane Library
Summary: Surgical decompression for people with severe brain swelling after stroke – Cochrane Library
RCT | Impact of empagliflozin on decongestion in acute heart failure.
23 Nov, 2022 | 14:04h | UTCCommentary: Empagliflozin in Patients Hospitalized for Acute Heart Failure – EMPULSE – American College of Cardiology
Commentary on Twitter
What's the impact of empagliflozin on decongestion in acute heart failure? New insights from the EMPULSE trial in EHJ!https://t.co/O1MZTFPWCc#SGLT2 #decongestion #heartfailure #empagliflozin #cardiotwitter @escardio @ESC_Journals pic.twitter.com/QLJYNgl1Zo
— EHJ Editor-in-Chief (@ehj_ed) October 19, 2022
Under a https://creativecommons.org/licenses/by-nc/4.0/ license
Right heart failure in the ED: approach to diagnosis and management.
23 Nov, 2022 | 13:54h | UTCRight Heart Failure in the ED: Approach to Diagnosis and Management – emDocs
M-A | Use of CT of the head in patients with acute atraumatic altered mental status.
22 Nov, 2022 | 13:38h | UTC
Commentary on Twitter
Meta-analysis: 94% of patients with atraumatic altered mental status received a noncontrast CT head, with an average yield of 11% which varied by setting: 18% in ED patients, 12% of ICU patients, and 3% of general inpatients had positive findings on CT. https://t.co/yHWj6uSwTM
— JAMA Network Open (@JAMANetworkOpen) November 18, 2022
RCT | NIV is superior to high-flow nasal cannula to prevent reintubation in patients at high risk for extubation failure.
21 Nov, 2022 | 14:41h | UTCEffect of postextubation noninvasive ventilation with active humidification vs high-flow nasal cannula on reintubation in patients at very high risk for extubation failure: a randomized trial – Intensive Care Medicine (free for a limited period)
Commentary on Twitter
NIV + active humidification vs HFNC in adult critically ill pts at very high-risk for extubation failure, RCT in 🇪🇸 ICUs: noninvasive ventilation superior to high-flow nasal cannula O2
➡️ reintubation required in 23.3% pts receiving NIV vs 38.8% if HFNC
📎 https://t.co/2mNTf3PYEF pic.twitter.com/Fp2GtZpcLx— Intensive Care Medicine (@yourICM) November 19, 2022
International guidelines and consensus on the use of lung ultrasound.
21 Nov, 2022 | 14:30h | UTC