Critical Care
Review | Management of cardiogenic shock after acute coronary syndromes
18 Apr, 2023 | 13:27h | UTCManagement of cardiogenic shock after acute coronary syndromes – BJA Education
Commonly encountered central nervous system infections in the intensive care unit
18 Apr, 2023 | 13:17h | UTCCommonly encountered central nervous system infections in the intensive care unit – BJA Education
Guidelines for the management of adult acute and acute-on-chronic liver failure in the ICU
17 Apr, 2023 | 13:19h | UTCGuidelines for the Management of Adult Acute and Acute-on-Chronic Liver Failure in the ICU: Neurology, Peri-Transplant Medicine, Infectious Disease, and Gastroenterology Considerations – Critical Care Medicine (free for a limited period)
Executive Summary: Guidelines for the Management of Adult Acute and Acute-on-Chronic Liver Failure in the ICU: Neurology, Peri-Transplant Medicine, Infectious Disease, and Gastroenterology Considerations – Critical Care Medicine (free for a limited period)
Consensus Paper | Strategies to prevent Clostridioides difficile infections in acute-care hospitals
17 Apr, 2023 | 13:17h | UTCCommentary: New guidance deems antibiotic stewardship essential for preventing C diff infections – CIDRAP
National clinical guideline for stroke for the UK and Ireland
17 Apr, 2023 | 13:15h | UTCNational clinical guideline for stroke for the UK and Ireland – Stroke Working Party (Full PDF here)
Propofol and survival: an updated meta-analysis of randomized clinical trials
17 Apr, 2023 | 13:09h | UTCPropofol and survival: an updated meta-analysis of randomized clinical trials – Critical Care
Commentary on Twitter (thread – click for more)
Big headline: 252 RCTs looking at more than 30,000 patients show propofol increases mortality compared to ‘other’ (RR 1.10, 95% CI 1.01-1.20, p = 0.03). This translates to an NNH of 235.
Interesting one. Where does the effect stem from? 1/8https://t.co/8z8Z1OE0I3
— Jan Hansel (@VirtueOfNothing) April 14, 2023
SR | Oral direct thrombin inhibitors vs. conventional anticoagulants for the treatment of pulmonary embolism
17 Apr, 2023 | 13:02h | UTC
Cohort Study | Major cardiovascular events after spontaneous intracerebral hemorrhage by hematoma location
12 Apr, 2023 | 13:13h | UTCInvited Commentary: Major Adverse Cardiovascular Events After Intracerebral Hemorrhage—It’s All About Location, Location, Location – JAMA Network Open
Review | Managing respiratory muscle weakness during weaning from invasive ventilation
11 Apr, 2023 | 14:12h | UTC
M-A | Noninvasive respiratory support after extubation
11 Apr, 2023 | 14:03h | UTC
Brief Review | Ten tips on fever in the ICU
10 Apr, 2023 | 14:02h | UTCTen tips on fever – Intensive Care Medicine
ESO expedited recommendation on tenecteplase for acute ischemic stroke
10 Apr, 2023 | 13:44h | UTCRelated:
RCT | Tenecteplase noninferior to alteplase in acute ischemic cerebrovascular events
RCT: Tenecteplase vs. alteplase for the management of acute ischemic stroke.
Randomized Controlled Trial: Tenecteplase vs Alteplase before Thrombectomy for Ischemic Stroke
Position Statement | Neuroprognostication in the post cardiac arrest patient
10 Apr, 2023 | 13:46h | UTC
Review | Cardiogenic shock classification and associated mortality risk
10 Apr, 2023 | 13:42h | UTCCardiogenic Shock Classification and Associated Mortality Risk – Mayo Clinic Proceedings
Perspective | ARDS complicating traumatic brain injury. Can opposite strategies converge?
10 Apr, 2023 | 13:39h | UTCAcute respiratory distress syndrome complicating traumatic brain injury. Can opposite strategies converge? – Intensive Care Medicine (free for a limited period)
M-A | High-flow nasal cannula vs. noninvasive positive pressure ventilation in acute hypoxic respiratory failure
10 Apr, 2023 | 13:37h | UTC
Cohort Study | Clinical features, etiologies, and outcomes in adult patients with meningoencephalitis requiring intensive care
10 Apr, 2023 | 13:38h | UTCClinical features, etiologies, and outcomes in adult patients with meningoencephalitis requiring intensive care (EURECA): an international prospective multicenter cohort study – Intensive Care Medicine (free for a limited period)
Commentary on Twitter
? Meningoencephalitis in adults requiring #ICU, EURECA study
➡️ poor outcomes at 3 months (moderate-to-severe disability or death) in ½ pts
➡️ older age, immunodepression, neurologic presentation nonmodifiable factors associated w poor outcome.#FOAMcc
?️ https://t.co/AR3w8x0Hiy pic.twitter.com/ChoucOnP8B— Intensive Care Medicine (@yourICM) April 7, 2023
Review | Refeeding Syndrome: diagnostic challenges and the potential of clinical decision support systems
10 Apr, 2023 | 13:28h | UTC
RCT | Routine invasive approach fails to benefit frail older adults with non–ST-segment elevation acute myocardial infarction
6 Apr, 2023 | 13:23h | UTCEffect of Routine Invasive vs Conservative Strategy in Older Adults With Frailty and Non–ST-Segment Elevation Acute Myocardial Infarction: A Randomized Clinical Trial – JAMA Internal Medicine (link to abstract – $ for full-text)
Commentary on Twitter
A routine invasive strategy did not improve clinical outcomes in frail patients with NSTEMI. Future trials should confirm whether a policy of watchful observation rather than routine invasive management may be effective for these patients. https://t.co/N4hAXg5fid
— JAMA Internal Medicine (@JAMAInternalMed) March 6, 2023
M-A | Comparison of the diagnostic accuracies of monocyte distribution width, procalcitonin, and C-reactive protein for sepsis
6 Apr, 2023 | 13:00h | UTC
Cohort Study | Maternal cardiac arrest: occurrence, survival, and influencing factors
6 Apr, 2023 | 12:59h | UTCCardiac Arrest During Delivery Hospitalization: A Cohort Study – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentaries:
Cardiac Arrest During Delivery Hospitalization – American College of Cardiology
Cardiac Arrest During Childbirth Is Rare, But Some Women Face Higher Risks – HealthDay
Commentary on Twitter
Study of pregnant women hospitalized during delivery found #CardiacArrest occurred in 1 in 9k deliveries, higher than other reported rates. More common in older or Black patients or persons w/ #Medicare or underlying conditions: https://t.co/ko1K7NFaPi. @CDCgov pic.twitter.com/23CxVi138k
— Annals of Int Med (@AnnalsofIM) March 15, 2023
Cohort Study | Multimodal prediction of favorable outcome after cardiac arrest
6 Apr, 2023 | 13:01h | UTC
ERS/ESICM/ESCMID/ALAT guidelines for the management of severe community-acquired pneumonia
5 Apr, 2023 | 13:45h | UTC
Commentary on Twitter
Management of severe community-acquired pneumonia: @EuroRespSoc @ESICM @ESCMID @ALATorax international guidelines
➡️ evidence-based recommendations for diagnosis, empirical treatment, ABTs
➡️ current knowledge gaps
➡️ recommendations for future research
?️ https://t.co/qhe1wlgN9t pic.twitter.com/LMNCbauYfs— Intensive Care Medicine (@yourICM) April 4, 2023
Review | Diagnosis and treatment of acute myocarditis
5 Apr, 2023 | 13:40h | UTCDiagnosis and Treatment of Acute Myocarditis: A Review – JAMA (free for a limited period)
RCT | Endovascular treatment vs. no treatment after 6-24h in ischemic stroke patients with collateral flow on CT angiography
5 Apr, 2023 | 13:38h | UTCEndovascular treatment versus no endovascular treatment after 6–24 h in patients with ischaemic stroke and collateral flow on CT angiography (MR CLEAN-LATE) in the Netherlands: a multicentre, open-label, blinded-endpoint, randomised, controlled, phase 3 trial – The Lancet (link to abstract – $ for full-text)