Critical Care
Clinical aspects of snakebite envenoming and its treatment in low-resource settings
2 May, 2023 | 13:21h | UTCClinical aspects of snakebite envenoming and its treatment in low-resource settings – The Lancet (free registration required)
Pre-Post Study | Machine learning informs mortality risk, increases advanced care planning rates in hospitalized patients
28 Apr, 2023 | 12:54h | UTC
Commentary on Twitter
Communicating mortality predictions from #MachineLearning algorithm to hospitalists may help increase goals of care discussions with high-risk hospitalized patients. https://t.co/dyCmwybcJb @WashUi2db @HealthHandbook
— JAMA Network Open (@JAMANetworkOpen) April 19, 2023
Extracorporeal CPR dissemination and integration with organ preservation in the USA: ethical and logistical considerations
28 Apr, 2023 | 12:47h | UTC
M-A | Corticosteroids in community-acquired bacterial pneumonia
26 Apr, 2023 | 14:29h | UTCCorticosteroids in Community-Acquired Bacterial Pneumonia: a Systematic Review, Pairwise and Dose-Response Meta-Analysis – Journal of General Internal Medicine (if the link is paywalled, try this one)
Related:
RCT | Hydrocortisone reduces mortality in severe community-acquired pneumonia
ERS/ESICM/ESCMID/ALAT guidelines for the management of severe community-acquired pneumonia
M-A | Utility of differential time to positivity in diagnosing central line associated bloodstream infections
26 Apr, 2023 | 14:24h | UTC
Commentary on Twitter
Utility of Differential Time to Positivity in Diagnosing Central Line Associated Bloodstream Infections: A Systematic Review and Meta-Analysis
✅ Just Accepted
? Freely Availablehttps://t.co/TQYs2qhvdm— Clinical Infectious Diseases (@CIDJournal) April 19, 2023
Position Paper | Emergency point-of-care ultrasound stewardship
26 Apr, 2023 | 14:15h | UTC
Review | Sepsis-associated delirium
26 Apr, 2023 | 14:10h | UTCSepsis-Associated Delirium: A Narrative Review – Journal of Clinical Medicine
PEEP-test study | The increase in cardiac output induced by a decrease in PEEP reliably detects volume responsiveness
26 Apr, 2023 | 14:03h | UTC
RCT | The effectiveness of early surgical stabilization for multiple rib fractures
26 Apr, 2023 | 14:01h | UTCRelated:
RCT | Operative vs. nonoperative treatment of acute unstable chest wall injuries.
RCT | Rib fixation is not beneficial for non–ventilator-dependent chest wall injuries.
M-A | Prevalence of atypical pathogens in patients with severe pneumonia
26 Apr, 2023 | 14:02h | UTC
Review | What the clinician needs to know about medical nutrition therapy in critically ill patients in 2023
26 Apr, 2023 | 13:59h | UTC
Perspective | Liver transplantation for patients with severe acute on chronic liver failure: it is time to change paradigms
25 Apr, 2023 | 14:37h | UTC
Commentary on Twitter
Liver #Tx in severe acute on chronic failure
➡️ #ICU care crucial in ACLF-3
➡️ improve referrals to LT centers & pre-LT workup
➡️ to decide to put pt on waitlist consider donor shortage/collective utility of LT
➡️ identifying transplantability window
?️ https://t.co/VZxDyZ1k74 pic.twitter.com/6YOcd5rzMu— Intensive Care Medicine (@yourICM) April 19, 2023
Cohort Study | Osmotic demyelination syndrome in patients hospitalized with hyponatremia
25 Apr, 2023 | 14:26h | UTCOsmotic Demyelination Syndrome in Patients Hospitalized with Hyponatremia – NEJM Evidence
RCT | Higher dose corticosteroids increase mortality in hypoxic COVID-19 patients on simple oxygen
24 Apr, 2023 | 13:55h | UTCEditorial: Higher-dose dexamethasone for patients with COVID-19 and hypoxaemia? – The Lancet
Commentary: Higher-dose corticosteroids tied to 60% more deaths in low-oxygen COVID patients – CIDRAP
Commentary on Twitter (thread – click for more)
Low-dose corticosteroids have been shown to reduce mortality for patients with COVID-19 requiring oxygen or ventilatory support.
A new study evaluated the use of a higher dose of corticosteroids in this patient group. https://t.co/uJGSYSBQAO
— The Lancet (@TheLancet) April 13, 2023
Prehospital guidelines for the management of traumatic brain injury
24 Apr, 2023 | 13:45h | UTC
Immediate hypersensitivity reactions to antineoplastic agents – A practical guide for the oncologist
24 Apr, 2023 | 13:40h | UTCImmediate hypersensitivity reactions to antineoplastic agents – A practical guide for the oncologist- Cancer Treatment Reviews (free for a limited period)
See Tweet from one of the authors with infographic and link to free full text here
Cohort Study | Prehospital end-tidal CO2 levels and mortality in suspected severe traumatic brain injury patients
24 Apr, 2023 | 13:35h | UTCEditorial: Prehospital ventilation targets in severe traumatic brain injury – Intensive Care Medicine
Commentary on Twitter
Prehospital etCO2 in severe #TBI, BRAIN-PROTECT study
? L-shaped association with mortality
? 35-45 mmHg seems reasonable target: lower ETCO2? sharp mortality ⬆️
?️ https://t.co/DC0DoHa00NWith editorial on MV targets & reliability of available data
?️ https://t.co/jVZ4zZVHxv pic.twitter.com/74vKxjyGpA— Intensive Care Medicine (@yourICM) April 20, 2023
Brief Review | Acute kidney injury
24 Apr, 2023 | 13:24h | UTCAcute kidney injury – Intensive Care Medicine (if the link is paywalled, try this one)
Commentary on Twitter
Acute kidney injury common in #ICU, influencing outcomes: not only focus on prevention, optimize treatment! In this review:
? prevention
? conservative management
? optimal timing of initiation of RR
? longer-term post #AKI follow-up@ForniLuiG
?️ https://t.co/SPz70YfJIK pic.twitter.com/qGqo08CP6E— Intensive Care Medicine (@yourICM) April 18, 2023
Brief Review | The use of high-flow nasal oxygen
24 Apr, 2023 | 13:23h | UTCThe use of high-flow nasal oxygen – Intensive Care Medicine (if the link is paywalled, try this one)
Commentary on Twitter
The use of high‑flow nasal oxygen:
? acute hypoxemic respiratory failure
? acute hypercapnic respiratory failure
? weaning from mechanical ventilation
? special populations: immunocompromised patients & tracheostomised patients
?️ https://t.co/3ZzGabkh0M pic.twitter.com/ieVCWjPDwE— Intensive Care Medicine (@yourICM) April 20, 2023
Brief Review | Aerosolized antibiotics in critical care
24 Apr, 2023 | 13:21h | UTCAerosolised antibiotics in critical care – Intensive Care Medicine
Related: How to Use Nebulized Antibiotics in Severe Respiratory Infections – Antibiotics
Commentary on Twitter
Aerosolised antibiotics in #ICU
? delivery to tracheobronchial tree? easy
? delivery to infected lung parenchyma? difficult
? clinical delivery of aerosolized ABTS
? how to address unmet clinical needs from a research standpoint
Free to read #FOAMcc
?️ https://t.co/tLjcvyUpY7 pic.twitter.com/brhTAGczRr— Intensive Care Medicine (@yourICM) April 22, 2023
RCT | Peri-intubation hypoxia after delayed vs. rapid sequence intubation in critically injured patients on arrival to trauma triage
24 Apr, 2023 | 13:04h | UTCPeri-Intubation Hypoxia After Delayed Versus Rapid Sequence Intubation in Critically Injured Patients on Arrival to Trauma Triage: A Randomized Controlled Trial – Anesthesia & Analgesia (link to abstract – $ for full-text)
Review | The management of pregnant trauma patients
24 Apr, 2023 | 13:01h | UTCThe Management of Pregnant Trauma Patients: A Narrative Review – Anesthesia & Analgesia (free for a limited period)
See also: Infographic (free for a limited period)
ACSM expert consensus statement on exertional heat illness: recognition, management, and return to activity
19 Apr, 2023 | 13:27h | UTCRelated:
Exertional heat stroke: pathophysiology and risk factors – BMJ Medicine
Classic and exertional heatstroke – Nature Reviews Disease Primers
Treatment and Prevention of Heat-Related Illness – New England Journal of Medicine
Ischemia with nonobstructive coronary artery disease: concept, assessment, and management
19 Apr, 2023 | 13:17h | UTCRelated:
Review: Myocardial infarction with non-obstructive coronary artery disease.
MINOCA from A to Z – American College of Cardiology
Global Survey | Incidence, management and prognosis of esophageal fistula after atrial fibrillation catheter ablation
19 Apr, 2023 | 13:14h | UTCCommentary: Esophageal Fistula Still a Rare but Deadly Complication of AF Ablation: POTTER-AF – TCTMD
Commentary from the author on Twitter
?The POTTER-AF study
➡️published #EHJ online
➡️138 oesophageal fistulas
➡️incidence 0,025% overall, ?RF 0.038%, ❄️CRYO 0.0015%
☠️Mortality: 90% if treated conservative!
?V. Schmidt, @KeelaniAhmad @ChristianHeeger@AGEP_DGK @ESC_Journals #UKSHhttps://t.co/jTmC36wlYQ #EPeeps pic.twitter.com/3lntY6lR6H— Roland Tilz (@RolandTilz) April 16, 2023