Chest Medicine (all articles)
Covid-19: Norway investigates 23 deaths in frail elderly patients after vaccination
17 Jan, 2021 | 22:21h | UTCCovid-19: Norway investigates 23 deaths in frail elderly patients after vaccination – The BMJ
See also: Covid-19 vaccination associated with adverse drug reactions in elderly people who are frail
Herd immunity by infection is not an option
17 Jan, 2021 | 22:16h | UTCHerd immunity by infection is not an option – Science
CDC Study: Performance of an antigen-based test for asymptomatic and symptomatic SARS-CoV-2
17 Jan, 2021 | 22:10h | UTC
Commentary on Twitter
New @CDCMMWR shows COVID-19 antigen tests can be fast and inexpensive but sometimes require a second test to confirm the result. Protect others until your test result is confirmed. Learn more: https://t.co/xu4buZMM0K. pic.twitter.com/GbRfrFscKI
— CDC (@CDCgov) December 31, 2020
Meta-analysis: Prophylactic macrolides beneficial for patients with COPD with frequent exacerbations
17 Jan, 2021 | 22:09h | UTCSummary: Prophylactic antibiotics for people with COPD – Cochrane Library
Position paper: Chest CT diagnosis and clinical management of drug-related pneumonitis in patients receiving molecular targeting agents and immune checkpoint inhibitors
17 Jan, 2021 | 22:07h | UTC
Randomized trial: In patients hospitalized with community-acquired pneumonia, adjunctive oral dexamethasone reduced the length of stay and ICU admissions, with no difference in mortality rates
17 Jan, 2021 | 21:58h | UTCAdjunctive treatment with oral dexamethasone in non-ICU patients hospitalised with community-acquired pneumonia: A randomised clinical trial – European Respiratory Journal (link to abstract – $ for full-text)
Study: Vaping combined with smoking may be as harmful as smoking cigarettes alone
17 Jan, 2021 | 21:53h | UTCCommentaries: Vaping combined with smoking is likely as harmful as smoking cigarettes alone, study finds – American Heart Association AND CVD Biomarker Levels Up for Dual Use of E-Cigarettes, Cigarettes – Physician’s Weekly
Randomized trial: Inhaled Treprostinil in pulmonary hypertension due to interstitial lung disease
17 Jan, 2021 | 21:47h | UTCCommentaries: Inhaled Treprostinil Beneficial in Pulmonary Hypertension – HealthDay
Commentary on Twitter
Patients with pulmonary hypertension due to interstitial lung disease were randomly assigned to inhale treprostinil or placebo. At 16 weeks, there was a significant improvement in exercise capacity with inhaled treprostinil as compared with placebo, assessed by a 6-minute walk.
— NEJM (@NEJM) January 14, 2021
Meta-analysis: Safety and efficacy of dexmedetomidine in acutely ill adults requiring non-invasive ventilation
17 Jan, 2021 | 21:42h | UTCSafety and efficacy of dexmedetomidine in acutely ill adults requiring non-invasive ventilation: a systematic review and meta-analysis of randomized trials – CHEST (link to abstract – $ for full-text)
Observational study: Among patients hospitalized with Covid-19 not receiving mechanical ventilation, transfusion of plasma with higher anti–SARS-CoV-2 IgG antibody levels is linked to lower risk of death than transfusion of plasma with lower antibody levels
15 Jan, 2021 | 08:59h | UTCEditorial: (A Little) Clarity on Convalescent Plasma for Covid-19 – New England Journal of Medicine
Commentaries: Expert reaction to study looking at convalescent plasma antibody levels and risk of death from COVID-19 – Science Media Centre AND Antibody-rich convalescent plasma may lower risk of COVID death – CIDRAP
Opinion: RCTs don’t justify using convalescent plasma or antibody cocktails
15 Jan, 2021 | 08:58h | UTCRCTs don’t justify using convalescent plasma or antibody cocktails – PulmCrit
[Preprint] Past COVID-19 infection provides some immunity but people may still carry and transmit virus
15 Jan, 2021 | 09:02h | UTCSee also: Covid-19: Past infection provides 83% protection for five months but may not stop transmission, study finds – The BMJ AND COVID reinfections are unusual — but could still help the virus to spread – Nature AND COVID-19 infection gives some immunity, but virus can still be spread, study finds – Reuters AND Expert reaction to a preprint from the SIREN study looking at SARS-CoV-2 infection rates in antibody positive healthcare workers – Science Media Centre
Perspective: Ivermectin for COVID-19 — Breakthrough Treatment or Hydroxychloroquine Redux?
15 Jan, 2021 | 08:51h | UTCRelated video: Ivermectin For COVID-19 | A Doctor Explains – ZDoggMD
NIH Guideline Statement: “there are insufficient data to recommend either for or against the use of ivermectin for the treatment of COVID-19”
15 Jan, 2021 | 08:53h | UTC
Covid-19 Vaccine — Frequently Asked Questions
15 Jan, 2021 | 08:49h | UTCCovid-19 Vaccine — Frequently Asked Questions – New England Journal of Medicine
Covid-19: When to start invasive ventilation is “the million dollar question”
15 Jan, 2021 | 08:48h | UTCCovid-19: When to start invasive ventilation is “the million dollar question” – The BMJ
Commentary on Twitter
Options for ventilating covid-19 patients have expanded since the first wave of the pandemic, but doctors are unsure of the best management pathway because evidence is lacking, reports @ingridtorjesenhttps://t.co/iKldASmahF
— The BMJ (@bmj_latest) January 14, 2021
Clinical trial finds vitamin D does not ward off colds and flu
15 Jan, 2021 | 08:33h | UTC
Study: Pulmonary embolism detected in 6% of patients with COPD admitted to the hospital with acute worsening of respiratory symptoms
15 Jan, 2021 | 08:37h | UTCPrevalence of Pulmonary Embolism Among Patients With COPD Hospitalized With Acutely Worsening Respiratory Symptoms – JAMA (link to abstract – $ for full-text)
CoronaVac study in Brazil: Is the vaccine 50%, 78%, or 100% effective?
14 Jan, 2021 | 02:11h | UTCThird time’s the charm? Brazil scales back efficacy claims for COVID-19 vaccine from China – Science
See also: CoronaVac’s Overall Efficacy in Brazil Measured at 50.4% – Bloomberg
Meta-analysis: Saliva vs. nasopharyngeal swabs equally sensitive for Covid-19 diagnosis
14 Jan, 2021 | 02:13h | UTCCommentary: Saliva, Nasopharyngeal Samples Equally Sensitive for SARS-CoV-2 – Physician’s Weekly
Commentary on Twitter
Nasopharyngeal swab or saliva to diagnose covid-19?
A systematic review of 37 studies, 7332 paired sampleshttps://t.co/mOTpXSz8I3@AnnalsofIM supports saliva being as sensitive and less costly, "should replace NP swabs in most populations being tested," by @mcgillu pic.twitter.com/cfSKVbFGlw— Eric Topol (@EricTopol) January 11, 2021
Pragmatic Recommendations for the Management of COVID-19 in Low- and Middle-Income Countries
14 Jan, 2021 | 02:04h | UTC- Editorial: Recommendations for the Management of COVID-19 in Low- and Middle-Income Countries – The American Journal of Tropical Medicine and Hygiene
- Pragmatic Recommendations for the Management of Acute Respiratory Failure and Mechanical Ventilation in Patients with COVID-19 in Low- and Middle-Income Countries – The American Journal of Tropical Medicine and Hygiene
- Pragmatic Recommendations for the Management of Anticoagulation and Venous Thrombotic Disease for Hospitalized Patients with COVID-19 in Low- and Middle-Income Countries – The American Journal of Tropical Medicine and Hygiene
- Pragmatic Recommendations for Identification and Triage of Patients with COVID-19 Disease in Low- and Middle-Income Countries – The American Journal of Tropical Medicine and Hygiene
- Pragmatic Recommendations for Tracheostomy, Discharge, and Rehabilitation Measures in Hospitalized Patients Recovering From Severe COVID-19 in Low- and Middle-Income Countries – The American Journal of Tropical Medicine and Hygiene
- Pragmatic Recommendations for the Prevention and Treatment of Acute Kidney Injury in Patients with COVID-19 in Low- and Middle-Income Countries – The American Journal of Tropical Medicine and Hygiene
- Pragmatic Recommendations for Infection Prevention and Control Practices for Healthcare Facilities in Low- and Middle-Income Countries during the COVID-19 Pandemic – Journal of Tropical Medicine and Hygiene
Study estimates 50% of new SARS-CoV-2 infections have originated from exposure to asymptomatic or pre-symptomatic individuals
14 Jan, 2021 | 02:08h | UTCSARS-CoV-2 Transmission From People Without COVID-19 Symptoms – JAMA Network Open
Commentary: At least 50% of COVID-19 cases spread from people without symptoms, a new study found – Business Insider AND More than half of Covid-19 infections acquired from asymptomatic carriers – MedicalResearch
Commentary on Twitter
More useful science.
More than half of cases likely to have been picked up from people who don’t know they have COVID.
Act like you have COVID. Act like they have COVID. We can slow the spread. https://t.co/RHqZhVWKmM
— Ruth Tennant (@TennantRuth) January 10, 2021
Imaging of Pulmonary Hypertension in Adults: A Position Paper from the Fleischner Society
14 Jan, 2021 | 01:51h | UTC
Systematic review: Does behavioral support help people to stop smoking?
14 Jan, 2021 | 01:46h | UTCSummary: Does behavioural support help people to stop smoking? – Cochrane Library
Systematic review: Immunotherapy vs. chemotherapy for people with advanced non-small cell lung cancer who have not been previously treated
14 Jan, 2021 | 01:30h | UTC
#Immunotherapy vs #chemotherapy for people with advanced non‐small cell #lungcancer who have not been not previously been treated https://t.co/RJlDp1SHTc New @CochraneLibrary systematic review includes 7 studies with 5893 participants.
— The Cochrane Library (@CochraneLibrary) December 21, 2020