Chest Medicine
Cohort study showed that the incidence of Multisystem Inflammatory Syndrome in Children (MIS-C) was 316 persons per 1 000 000 SARS-CoV-2 infections in persons younger than 21 years. The incidence was higher among Black, Hispanic or Latino, and Asian or Pacific Islander persons.
14 Jun, 2021 | 08:48h | UTCCommentary: MIS-C Incidence 316 Persons Per 1 Million SARS-CoV-2 Infections – HealthDay
Commentary on Twitter
About 1 in every 3,000 children who got COVID ended up with MIS-C. MIS-C incidence among Black persons and Hispanic or Latino persons was approximately 9x higher, and incidence among Asian or Pacific Islander persons was approximately 3x higher https://t.co/JTEsvgvFcz
— Daniel Griffin MD PhD (@DanielGriffinMD) June 12, 2021
RCT: No difference in 30-day mortality with discontinuation vs. continuation of renin-angiotensin-system inhibitors in patients with COVID-19, but secondary and explorative analysis showed discontinuation of RAS-inhibition may lead to a faster and better recovery.
14 Jun, 2021 | 08:47h | UTCEditorial: RAS inhibition and COVID-19: more questions than answers?
Related randomized trials showing no benefit from discontinuation: Randomized trial: No benefit from discontinuing ACE Inhibitors and ARBs in patients admitted with COVID-19 AND Randomized trial: Renin–angiotensin system inhibitors can be safely continued in patients admitted to hospital with COVID-19
Video | Evaluation and care of patients with persistent symptoms following acute SARS-CoV-2 infection.
14 Jun, 2021 | 08:45h | UTC
Covid: Is there a limit to how much worse variants can get?
14 Jun, 2021 | 08:43h | UTCCovid: Is there a limit to how much worse variants can get? – BBC
WHO: More than 100 reasons to quit tobacco.
14 Jun, 2021 | 08:38h | UTCMore than 100 reasons to quit tobacco – World Health Organization
Commentary on Twitter (thread – click for more)
Quitting tobacco 🚭 can be challenging but there are more than 💯 reasons to #CommitToQuit & start living a healthier life.
Find out more 👉https://t.co/8uBEMvH0cu pic.twitter.com/iwrt86xSVo
— World Health Organization (WHO) (@WHO) June 13, 2021
Pulmonary Exacerbations in Adults With Cystic Fibrosis: A Grown-up Issue in a Changing Cystic Fibrosis Landscape.
14 Jun, 2021 | 08:35h | UTC
High COVID vaccine uptake may protect the unvaccinated.
11 Jun, 2021 | 08:34h | UTCHigh COVID vaccine uptake may protect the unvaccinated – CIDRAP
Original Study: Community-level evidence for SARS-CoV-2 vaccine protection of unvaccinated individuals – Nature Medicine
Commentaries on Twitter
Just published @NatureMedicine
Evidence that "vaccination not only protects individuals who have been vaccinated but also provides cross-protection to unvaccinated individuals in the community" as seen in kids benefiting from high % of adults vaxxedhttps://t.co/IPQo6WTFZX pic.twitter.com/jtfD93onnn— Eric Topol (@EricTopol) June 10, 2021
https://twitter.com/niklasf/status/1402950991268433923
Non-invasive oxygenation strategies for respiratory failure with COVID-19: A concise narrative review of literature in pre and mid-COVID-19 era.
11 Jun, 2021 | 08:25h | UTC
Naturally acquired SARS-CoV-2 immunity persists for up to 11 months following infection.
11 Jun, 2021 | 08:24h | UTC
Opinion | The Covid-19 Delta variant poses a threat to our return to ‘normal’.
11 Jun, 2021 | 08:23h | UTCThe Covid-19 Delta variant poses a threat to our return to ‘normal’ – CNN
Commentary on Twitter
https://twitter.com/HoltgraveHealth/status/1402948596476039171
M-A: Safety of thoracentesis and tube thoracostomy in patients with uncorrected coagulopathy.
11 Jun, 2021 | 08:15h | UTCCommentary: Is Thoracentesis Safe in Coagulopathic Patients? – JournalFeed
Editorial: Embrace the WHO’s new naming system for coronavirus variants.
10 Jun, 2021 | 09:48h | UTCEmbrace the WHO’s new naming system for coronavirus variants – Nature
Case series: Adjunct immune globulin for vaccine-induced thrombotic thrombocytopenia.
10 Jun, 2021 | 09:46h | UTC
Perspective | The four most urgent questions about long COVID.
10 Jun, 2021 | 09:47h | UTCThe four most urgent questions about long COVID – Nature
Perspective | Identifying and tracking SARS-CoV-2 variants — a challenge and an opportunity.
10 Jun, 2021 | 09:43h | UTC
[Preprint] RECOVERY trial finds aspirin does not improve survival for patients hospitalized with COVID-19.
9 Jun, 2021 | 08:28h | UTCNews Release: RECOVERY trial finds aspirin does not improve survival for patients hospitalised with COVID-19 – University of Oxford
Original Study: Aspirin in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial – medRxiv
Commentary on Twitter (thread – click for more)
RECOVERY Pre-print: Aspirin
14,892 patients randomised to aspirin vs. usual care
– no impact on all-cause mortality (17% vs. 17%)
– similar results in all pre-specified subgroupshttps://t.co/ay5Xg4GBVD pic.twitter.com/aNJ09RTTOa— Martin Landray (@MartinLandray) June 8, 2021
COVID-19 Imaging: What we know now and what remains unknown.
9 Jun, 2021 | 08:27h | UTCCOVID-19 Imaging: What We Know Now and What Remains Unknown – Radiology
Systematic review: Frequency, signs and symptoms, and criteria adopted for long COVID-19.
9 Jun, 2021 | 08:22h | UTC
Summary | WHO recommendations on the treatment of drug-resistant tuberculosis, 2020 update.
9 Jun, 2021 | 08:12h | UTCOriginal Guideline: WHO Consolidated Guidelines on Tuberculosis, Module 4: Treatment – Drug-Resistant Tuberculosis Treatment
Commentary on Twitter
🆕💥💥@ERSpublications
WHO guidelines on the treatment of drug-resistant TB contain the latest recommendations on shorter or longer all oral treatment regimens for patients with drug-resistant TB, including the medicines to be used& supportive measures https://t.co/qeeftVYdYN pic.twitter.com/4NKNNjz3Gh— Antibiotic Steward Bassam Ghanem 🅱️C🆔🅿️🌟 (@ABsteward) June 8, 2021
No health issues in babies whose moms got flu vaccine while pregnant.
9 Jun, 2021 | 08:17h | UTCNo health issues in babies whose moms got flu vaccine while pregnant – CIDRAP
Original study: Association of Maternal Influenza Vaccination During Pregnancy With Early Childhood Health Outcomes – JAMA (free for a limited period)
Editorial: Realizing the Potential of Maternal Influenza Vaccination (free for a limited period)
Commentary on Twitter
https://twitter.com/ericbenchimol/status/1402307635240706048
The “Black Fungus” in India: The Emerging Syndemic of COVID-19–Associated Mucormycosis – careful use of antibiotics and corticosteroids and closely monitoring blood glucose levels are some of the strategies suggested by the authors.
8 Jun, 2021 | 09:34h | UTC
Multicenter Epidemiologic Study of Coronavirus Disease–Associated Mucormycosis, India – Uncontrolled diabetes mellitus was the most common underlying disease; improper glucocorticoid use was independently associated with the disease.
8 Jun, 2021 | 09:33h | UTCCommentary: COVID19: Secondary Infections Still a Big Challenge in India – News Click
Commentary on Twitter
New study from India on mucormycosis
– COVID-19 has led to increases in mucormycosis, partly from inappropriate steroid use
– Uncontrolled diabetes was the most common underlying disease
Better diabetes care & rational steroid use are key!https://t.co/Wv8kCyTDtK pic.twitter.com/KK78BKg2Xf
— Madhu Pai, MD, PhD (@paimadhu) June 7, 2021
Report: 376,000 people in UK have had long Covid symptoms for at least a year.
8 Jun, 2021 | 09:27h | UTC376,000 people in UK have had long Covid symptoms for at least a year – ONS – The Guardian
Original report: Prevalence of ongoing symptoms following coronavirus (COVID-19) infection in the UK: 4 June 2021 – Office for National Statistics
Synopsis | Updates to the Pediatrics Asthma Management Guidelines.
8 Jun, 2021 | 09:22h | UTCUpdates to the Pediatrics Asthma Management Guidelines – JAMA Pediatrics (free for a limited period)
Original Guideline: 2020 Focused Updates to the Asthma Management Guidelines: A Report from the National Asthma Education and Prevention Program Coordinating Committee Expert Panel Working Group
RCT: In patients hospitalized with Covid-19 with elevated D-Dimer, a full-dose anticoagulation strategy based on rivaroxaban (full-dose heparins in unstable patients) + rivaroxaban to day 30 was not better than prophylactic anticoagulation and increased bleeding risk.
7 Jun, 2021 | 00:01h | UTC
Commentary on Twitter
https://twitter.com/RenatoDLopes1/status/1400962037610582026