Chest Medicine
Cohort study | High-risk patent foramen ovale associated with increased decompression illness in scuba divers
18 Jul, 2023 | 13:43h | UTCDecompression Illness in Divers With or Without Patent Foramen Ovale: A Cohort Study – Annals of Internal Medicine (link to abstract – $ for full-text)
News Release: SCUBA divers with PFO at higher risk for decompression illness than previously thought – American College of Physicians
Commentary on Twitter
A study of #ScubaDivers found presence of high-risk PFO was associated with increased risk of decompression illness. Authors recommend divers with PFO should consider not diving or adhering to more conservative protocol: https://t.co/5Glt9B8Xup pic.twitter.com/AYbrDxiL0p
— Annals of Int Med (@AnnalsofIM) July 11, 2023
Review | CT and chest radiography in evaluation of mechanical circulatory support devices for acute heart failure
18 Jul, 2023 | 13:28h | UTC
Consensus Statement | Aerosol therapy in adult critically ill patients
14 Jul, 2023 | 13:01h | UTC
M-A | Drug therapies for treatment of idiopathic pulmonary fibrosis
14 Jul, 2023 | 12:40h | UTC
M-A | Adjunctive corticosteroids improve survival, clinical outcomes in severe community-acquired pneumonia
13 Jul, 2023 | 13:09h | UTCRelated:
Corticosteroids in Community-Acquired Bacterial Pneumonia: a Systematic Review, Pairwise and Dose-Response Meta-Analysis – Journal of General Internal Medicine (if the link is paywalled, try this one)
RCT | Hydrocortisone reduces mortality in severe community-acquired pneumonia
ERS/ESICM/ESCMID/ALAT guidelines for the management of severe community-acquired pneumonia
RCT | Cytisinicline shows significant efficacy in smoking cessation over placebo
13 Jul, 2023 | 12:58h | UTCCytisinicline for Smoking Cessation: A Randomized Clinical Trial – JAMA (link to abstract – $ for full-text)
See also: Visual Abstract
AHA Scientific Statement | Pulmonary hypertension in congenital heart disease
11 Jul, 2023 | 13:57h | UTC
M-A | Catheter-directed thrombolysis vs. systemic thrombolysis and anticoagulation in intermediate- or high-risk pulmonary embolism
11 Jul, 2023 | 13:47h | UTC
M-A | Efficacy of varenicline versus bupropion for smoking cessation
10 Jul, 2023 | 13:23h | UTC
Review | Post-COVID Conditions
7 Jul, 2023 | 16:21h | UTCPost-COVID Conditions – Mayo Clinic Proceedings
Review | Hypereosinophilic syndrome (HES) and eosinophilic granulomatosis with polyangiitis (EGPA): two sides of the same coin
7 Jul, 2023 | 16:01h | UTCHES and EGPA: Two Sides of the Same Coin – Mayo Clinic Proceedings
SR | Antibiotic strategies for eradicating Pseudomonas aeruginosa in people with cystic fibrosis
5 Jul, 2023 | 01:04h | UTC
Review | Respiratory challenges and ventilatory management in different types of acute brain-injured patients
3 Jul, 2023 | 14:17h | UTC
Update on transfusion-related acute lung injury: an overview of its pathogenesis and management
30 Jun, 2023 | 14:31h | UTC
Review | Breathing difficulties after covid-19: a guide for primary care
29 Jun, 2023 | 14:04h | UTCBreathing difficulties after covid-19: a guide for primary care – The BMJ
The exposome in respiratory diseases: multiple preventable risk factors from early life to adulthood
27 Jun, 2023 | 13:32h | UTC
Commentary on Twitter
The increasing global burden of respiratory diseases over recent decades raises questions about the lifelong impact of environmental factors during industrialisation and urbanisation. There is a clear need for action in primary and secondary prevention. https://t.co/MFzkETBr2X pic.twitter.com/jp9LYSiSAR
— ERS publications (@ERSpublications) June 20, 2023
M-A | Risk factors for non-tuberculous mycobacterial pulmonary disease
27 Jun, 2023 | 13:27h | UTCCommentary: Comorbid respiratory disease key predictor of NTM-PD – MDedge
Cohort Study | Association of preterm birth with increased asthma and COPD risk in adulthood
26 Jun, 2023 | 00:45h | UTCSummary: This population-based register study investigated the correlation between gestational ages (GA) and obstructive airway diseases like asthma and chronic obstructive pulmonary disease (COPD) in adulthood. The study used registry data from 706,717 individuals born between 1987-1998 in Finland (4.8% preterm), and 1,669,528 individuals born from 1967-1999 in Norway (5.0% preterm). The study observed care episodes of asthma and COPD using nationwide healthcare registers.
The results showed an increased risk of obstructive airway disease in adulthood for those born at <28 or 28–31 completed weeks of gestation. Even after adjustments, the risk remained 2-3 times greater compared to those who were born full term (at 39-41 completed weeks). Additionally, the risk for COPD at age 30–50 was significantly higher for those born at <28 weeks, with an odds ratio (OR) of 7.44. The study also identified that bronchopulmonary dysplasia (BPD) in infancy increased the odds of obstructive airway disease for those born at <28 and 28–31 weeks.
These findings suggest that preterm birth is a notable risk factor for asthma and COPD in adulthood, and this risk was observed across all gestational ages before full term. The study recommends diagnostic vigilance for adults born very preterm presenting with respiratory symptoms. However, the researchers also noted the potential limitations of using registry data, which might include residual confounding from unmeasured confounders and lack of data on certain prenatal or early life factors.
Article: Preterm birth and asthma and COPD in adulthood: a nationwide register study from two Nordic countries – European Respiratory Journal (free for a limited period)
Commentary on Twitter
In this population-based study of 2.4 million people from Finland and Norway, adults born preterm were at higher risk for asthma and COPD at ages 18–50 years. The risks were observed across all gestational ages before full term in a dose-response manner. https://t.co/bGsAOrwAxV pic.twitter.com/WmCoc6cPu2
— ERS publications (@ERSpublications) June 22, 2023
Clinical insights into small cell lung cancer: tumor heterogeneity, diagnosis, therapy, and future directions
26 Jun, 2023 | 00:31h | UTC
Questions in mild asthma | An Official American Thoracic Society research statement
22 Jun, 2023 | 14:56h | UTC
Commentary on Twitter
Questions in Mild Asthma: An Official American Thoracic Society Research Statement
🔓 Open Access
🔗 https://t.co/qqMxWpqafX pic.twitter.com/XHrhpa73XI— ATS Blue Journal (@ATSBlueEditor) June 13, 2023
Review | Antifungal dosing in critically ill patients on extracorporeal membrane oxygenation
21 Jun, 2023 | 13:31h | UTC
RCT | Rituximab and MMF combo improves lung function vs. MMF in interstitial lung disease with NSIP pattern, but may increase infection risk
21 Jun, 2023 | 13:16h | UTCRituximab and mycophenolate mofetil combination in patients with interstitial lung disease (EVER-ILD): a double-blind, randomised, placebo-controlled trial – European Respiratory Journal (link to abstract – $ for full-text)
Commentary on Twitter
ERJ: Rituximab plus MMF is associated with benefits in lung function and progression-free survival compared with MMF plus placebo after 24 weeks of treatment. The safety profile of rituximab plus MMF was similar to that of MMF plus placebo. https://t.co/Mv0IuzLljz pic.twitter.com/1igrt6uDK4
— ERS publications (@ERSpublications) June 11, 2023
Review | Ultrasonographic assessment of diaphragmatic function in the management of patients with acute respiratory failure
21 Jun, 2023 | 13:12h | UTC
Review | Pulmonary rehabilitation and physical interventions
21 Jun, 2023 | 13:11h | UTCPulmonary rehabilitation and physical interventions – European Respiratory Review
Commentary on Twitter
ERR: Pulmonary rehabilitation that includes individualised exercise training is effective in patients with stable COPD and those who have suffered an exacerbation. Remaining challenges are to increase uptake and access to and personalisation of programmes. https://t.co/NSoASus6TW pic.twitter.com/JRl7dCOZrm
— ERS publications (@ERSpublications) June 12, 2023
Guideline | Management of patients with primary spontaneous pneumothorax
20 Jun, 2023 | 12:46h | UTC