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Chest Medicine

Cohort Study: SARS-CoV-2 co-infection with influenza viruses, respiratory syncytial virus, or adenoviruses is associated with increased mortality.

28 Mar, 2022 | 10:03h | UTC

SARS-CoV-2 co-infection with influenza viruses, respiratory syncytial virus, or adenoviruses – The Lancet

Commentary: Patients with Covid and flu double the risk of dying, say scientists – The Guardian

 

Commentary from the author on Twitter (thread – click for more)

https://twitter.com/kennethbaillie/status/1507501279181955076

 

Systematic Review: Symptom‐ and chest‐radiography screening for active pulmonary tuberculosis in HIV‐negative adults and adults with unknown HIV status.

28 Mar, 2022 | 08:54h | UTC

Symptom‐ and chest‐radiography screening for active pulmonary tuberculosis in HIV‐negative adults and adults with unknown HIV status – Cochrane Library

Summary: How accurate are asking about symptoms and doing a chest X-ray to screen for tuberculosis of the lungs among adults who are HIV-negative or with unknown HIV status? – Cochrane Library

 

RCT: In critically ill immunocompromised patients with acute respiratory failure, outcomes were similar with the use of high-flow nasal oxygen alone vs. alternating with non-invasive ventilation.

28 Mar, 2022 | 08:51h | UTC

High-flow nasal oxygen alone or alternating with non-invasive ventilation in critically ill immunocompromised patients with acute respiratory failure: a randomised controlled trial – The Lancet Respiratory Medicine (free registration required)

 

Commentary on Twitter

https://twitter.com/LancetRespirMed/status/1506175093474414592

 

A practical guide to implementing SMART in asthma management.

28 Mar, 2022 | 08:42h | UTC

A Practical Guide to Implementing SMART in Asthma Management – The Journal of Allergy and Clinical Immunology

 

Cochrane Special Collection: Diagnosing tuberculosis.

25 Mar, 2022 | 09:57h | UTC

Diagnosing tuberculosis – Cochrane Library

 

Review: Tobacco and nicotine use.

25 Mar, 2022 | 08:49h | UTC

Tobacco and nicotine use – Nature Reviews Disease Primers (if the link is paywalled, try this one)

Infographic: Tobacco and nicotine use (if the link is paywalled, try this one)

 

Commentary on Twitter

https://twitter.com/DiseasePrimers/status/1507089870950318118

 

[Preprint] RCT: Vitamin D supplements did not prevent Covid-19 or other acute respiratory infections.

25 Mar, 2022 | 09:49h | UTC

Vitamin D Supplements for Prevention of Covid-19 or other Acute Respiratory Infections: a Phase 3 Randomized Controlled Trial (CORONAVIT) – medRxiv

Related:

M-A: Low vitamin D levels do not aggravate COVID-19 risk or death, and vitamin D supplementation does not improve outcomes in hospitalized patients with COVID-19.

In a Mendelian randomization study, researchers found no genetic evidence to support an association between Vitamin D levels and COVID-19 susceptibility, severity, or hospitalization.

Living systematic review: The evidence is insufficient to determine the benefits and harms of vitamin D supplementation as a treatment of COVID‐19.

RCT: Vitamin D3 does not improve outcomes in hospitalized patients with moderate to severe COVID-19

 

Commentary on Twitter (thread – click for more)

https://twitter.com/KarlPfleger/status/1506871284214337543

 

M-A: Tuberculosis screening among HIV-positive inpatients.

25 Mar, 2022 | 08:35h | UTC

Tuberculosis screening among HIV-positive inpatients: a systematic review and individual participant data meta-analysis – The Lancet HIV

 

Commentary on Twitter

https://twitter.com/CarlosdelRio7/status/1506893108864335872

 

Systematic Review: Effectiveness and safety of pulse oximetry in remote patient monitoring of patients with COVID-19.

24 Mar, 2022 | 08:53h | UTC

Effectiveness and safety of pulse oximetry in remote patient monitoring of patients with COVID-19: a systematic review – The Lancet Digital Health

Commentaries:

Home blood oxygen monitoring can help COVID patients spot early warning signs – Imperial College London

Simple home oxygen monitors signal when to seek COVID care – CIDRAP

 

RCT: Awake prone positioning did not improve outcomes in patients with moderate hypoxemia due to covid-19.

24 Mar, 2022 | 09:48h | UTC

Prone positioning of patients with moderate hypoxaemia due to covid-19: multicentre pragmatic randomised trial (COVID-PRONE) – The BMJ

Editorial: Awake prone positioning for patients with covid-19

News Release: Lying prone long enough to improve outcomes is difficult for many covid-19 patients – BMJ

 

WHO releases clinical management guidelines for influenza.

23 Mar, 2022 | 10:41h | UTC

News Release: WHO releases clinical management guidelines for influenza – World Health Organization

Original Report: Guidelines for the clinical management of severe illness from influenza virus infections – World Health Organization

 

RCT: Among critically ill patients with Covid-19, treatment with an antiplatelet agent had a low likelihood of improving organ support–free days within 21 days.

23 Mar, 2022 | 10:38h | UTC

Effect of Antiplatelet Therapy on Survival and Organ Support–Free Days in Critically Ill Patients With COVID-19: A Randomized Clinical Trial – JAMA

Editorial: Thromboinflammation and Antithrombotics in COVID-19: Accumulating Evidence and Current Status – JAMA

Commentary: Aspirin may improve 3-month survival for patients critically ill with COVID-19 – Imperial College London

 

Commentaries on Twitter

https://twitter.com/JAMA_current/status/1506188937852858369

 

New WHO guidelines on the management of tuberculosis in children and adolescents.

22 Mar, 2022 | 09:52h | UTC

WHO consolidated guidelines on tuberculosis Module 5: Management of tuberculosis in children and adolescents – World Health Organization

Commentary: New Children’s TB Guidelines a ‘Game-Changer’ With Non-Invasive Tests, Shortened Treatments – Health Policy Watch

Related: RCT: In children with nonsevere, drug-susceptible tuberculosis, treatment for 4 months is noninferior to treatment for 6 months.

 

Review: When to operate after SARS-CoV-2 infection?

22 Mar, 2022 | 09:44h | UTC

When to operate after SARS-CoV-2 infection? A review on the recent consensus recommendation of the DGC/BDC and the DGAI/BDA – Langenbeck’s Archives of Surgery

Related:

Guideline Update: Timing of elective surgery and risk assessment after SARS-CoV-2 infection – “The guidance remains that patients should avoid elective surgery within 7 weeks of infection, unless the benefits of doing so exceed the risk of waiting”.

Perioperative cardiovascular considerations prior to elective noncardiac surgery in patients with a history of Covid-19.

Guideline: SARS‐CoV‐2 infection, COVID‐19 and timing of elective surgery

Study from 116 countries suggests surgery should be delayed for at least seven weeks following a COVID-19 diagnosis to reduce mortality risk

BJS commission on surgery and perioperative care post-COVID-19.

The risk of postoperative complications following major elective surgery in active or resolved COVID-19 in the United States – Major, elective surgery 0–4 weeks after Covid-19 is associated with greatly increased risk of postoperative complications; surgery performed 4–8 weeks after infection is still associated with an increased risk of pneumonia.

ASA Guidance: Preoperative testing for COVID-19 is essential, regardless of vaccination.

Position statement: Perioperative management of post-COVID-19 surgical patients.

Cohort study: Postoperative in-hospital mortality of patients with COVID-19 infection was more than double that in patients without COVID-19

 

Preventing and treating the common cold: what’s the evidence?

22 Mar, 2022 | 08:56h | UTC

Preventing and treating the common cold: what’s the evidence? – Evidently Cochrane

 

Commentary on Twitter

https://twitter.com/CochraneUK/status/1505978560078659587

 

Antigenic evolution will lead to new SARS-CoV-2 variants with unpredictable severity.

21 Mar, 2022 | 09:47h | UTC

Antigenic evolution will lead to new SARS-CoV-2 variants with unpredictable severity – Nature Reviews Microbiology

 

Commentary on Twitter

 

Infographic: IDSA COVID-19 outpatient treatment guidelines roadmap.

21 Mar, 2022 | 09:51h | UTC

COVID-19 Outpatient Treatment Guidelines Roadmap – Infectious Diseases Society of America

 

Commentary on Twitter

 

Large sleep database from the UK Biobank reveals a landscape of human sleep phenotypes.

21 Mar, 2022 | 08:41h | UTC

The 103,200-arm acceleration dataset in the UK Biobank revealed a landscape of human sleep phenotypes – Proceedings of the National Academy of Sciences

Commentary: Half a million nights’ sleep reveal 16 kinds of snoozer – Nature

 

More data suggests reduced risks of hospitalization and death due to SARS-CoV-2 Omicron compared to the Delta variant.

18 Mar, 2022 | 09:36h | UTC

Comparative analysis of the risks of hospitalisation and death associated with SARS-CoV-2 omicron (B.1.1.529) and delta (B.1.617.2) variants in England: a cohort study – The Lancet

Invited Commentary: Omicron: fewer adverse outcomes come with new dangers – The Lancet

 

Commentary on Twitter

 

M-A: Awake prone positioning for non-intubated patients with COVID-19-related acute hypoxemic respiratory failure.

18 Mar, 2022 | 09:32h | UTC

Awake prone positioning for non-intubated patients with COVID-19-related acute hypoxaemic respiratory failure: a systematic review and meta-analysis – The Lancet Respiratory Medicine

Invited Commentary: The pandemic and the great awakening in the management of acute hypoxaemic respiratory failure – The Lancet Respiratory Medicine

Related:

[Preprint] RCT: In hypoxic but not critically ill patients with COVID-19, an intervention to increase prone positioning did not improve outcomes.

RCT: Awake prone positioning reduces the need for intubation in patients with COVID-19.

RCT: Awake prone positioning in patients with hypoxemic respiratory failure due to COVID-19 – no difference in intubation rates compared to standard care.

M-A: Prone positioning of nonintubated patients with Covid-19 improve oxygenation variables without any reported serious adverse events – randomized trials with patient-relevant outcomes such as the need for intubation or mortality rates are required

 

Among health care workers, a fourth dose vaccine effectiveness against any SARS-CoV-2 Omicron variant infection was 30% for the Pfizer–BioNTech and 11% for the Moderna.

17 Mar, 2022 | 09:12h | UTC

Efficacy of a Fourth Dose of Covid-19 mRNA Vaccine against Omicron – New England Journal of Medicine

Related: [Preprint] Fourth dose of COVID vaccine offers only slight boost against Omicron infection.

 

Treatments for moderate to severe COVID-19: Cochrane evidence.

17 Mar, 2022 | 09:19h | UTC

Treatments for moderate to severe COVID-19: Cochrane evidence – Evidently Cochrane

 

Effectiveness of the Sputnik V, AstraZeneca, and Sinopharm vaccines for the risk of infection and death due to COVID-19 in people older than 60 years in Argentina.

17 Mar, 2022 | 09:10h | UTC

Effectiveness of rAd26-rAd5, ChAdOx1 nCoV-19, and BBIBP-CorV vaccines for risk of infection with SARS-CoV-2 and death due to COVID-19 in people older than 60 years in Argentina: a test-negative, case-control, and retrospective longitudinal study – The Lancet

Commentary: Evaluating COVID-19 vaccines in the real world – The Lancet

 

Treatments for mild COVID-19: Cochrane evidence.

17 Mar, 2022 | 09:17h | UTC

Treatments for mild COVID-19: Cochrane evidence – Cochrane Library

 

Denmark proposes ban on selling cigarettes to people born after 2010.

17 Mar, 2022 | 09:04h | UTC

Denmark proposes ban on selling cigarettes to people born after 2010 – euronews

Related: New Zealand to ban smoking for next generation in bid to outlaw habit by 2025 – “New legislation means the legal smoking age will increase every year, to create a smoke-free generation of New Zealanders”.

 

Commentary on Twitter

 

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