RCT: In critically ill immunocompromised patients with acute respiratory failure, outcomes were similar with the use of high-flow nasal oxygen alone vs. alternating with non-invasive ventilation.

High-flow nasal oxygen alone or alternating with non-invasive ventilation in critically ill immunocompromised patients with acute respiratory failure: a randomised controlled trial – The Lancet Respiratory Medicine (free registration required)

Commentary on Twitter

NEW Research—In critically ill immunocompromised patients with acute respiratory failure, the mortality rate did not differ between HFNO alone and NIV alternating with HFNO

FLORALI-IM study from Rémi Coudroy & co https://t.co/xSJfQ9yTCt

Presented today at @ISICEM #ISICEM2022 pic.twitter.com/ooHnRcVnFV

— The Lancet Respiratory Medicine (@LancetRespirMed) March 22, 2022