Chest Medicine
WHO Report: 9 out of 10 People Worldwide Breathe Polluted Air
4 May, 2018 | 02:08h | UTCRelated Infographics: PHE Infographics: Air pollution (free)
Updated Fact Sheets: Ambient (outdoor) air quality and health (free) AND Household air pollution and health (free)
Commentaries: Air pollution inequality widens between rich and poor nations – The Guardian (free) AND Expert reaction to new WHO global air pollution data – Science Media Centre (free)
Randomized Controlled Trial: Once-Daily Single-Inhaler Triple vs Dual Therapy in Patients with COPD
4 May, 2018 | 01:55h | UTCOnce-Daily Single-Inhaler Triple versus Dual Therapy in Patients with COPD – New England Journal of Medicine (link to abstract – $ for full-text)
Quick Take Video Summary: Single-Inhaler Triple Therapy in Patients with COPD (free)
Meta-Analysis: Direct Oral Anticoagulant vs Low-Molecular-Weight Heparin in Cancer Associated Thrombosis
4 May, 2018 | 01:59h | UTCSource: EvidenceAlerts
Summary: CHEST Guideline on Screening for Lung Cancer
4 May, 2018 | 01:54h | UTCScreening for Lung Cancer: CHEST Guideline – American College of Cardiology (free)
Original Guideline: Screening for Lung Cancer: CHEST Guideline and Expert Panel Report (free)
Summary: AHA Scientific Statement on Right Heart Failure
4 May, 2018 | 01:53h | UTCAHA Scientific Statement on Right Heart Failure – American College of Cardiology (free)
Original Guideline: Evaluation and Management of Right-Sided Heart Failure: A Scientific Statement From the American Heart Association (free PDF)
TOP Clinical Practice Guideline: Chronic Asthma
3 May, 2018 | 20:26h | UTCClinical Practice Guideline: Chronic Asthma – Toward Optimized Practice (free PDF)
See also: Summary (free PDF)
Related: see all TOP Clinical Practice Guidelines, a practical resource for Family Physicians at the point of care.
Review: Goodpasture’s syndrome (anti-GBM disease) in the ED
3 May, 2018 | 19:22h | UTCGoodpasture’s syndrome (anti-GBM disease): ED presentations, evaluation, and management – emDocs (free)
Debate: Should we Recommend e-Cigarettes to Help Smokers Quit?
27 Apr, 2018 | 01:36h | UTCShould we recommend e-cigarettes to help smokers quit? – The BMJ (free)
See also: related guidelines, reports and commentaries on e-cigarettes
“Experts debate: Should doctors recommend e-cigarettes to help smokers quit? Revelation in harm reduction or a way to keep people addicted and gateway to youth smoking?” (via @rich_hurley see Tweet)
Cohort Study: Proton‐Pump Inhibitors and Risk of Pneumonia in Older Adults
24 Apr, 2018 | 19:29h | UTCCommentary: Commonly prescribed heartburn drug linked to Pneumonia in Older Adults – University of Exeter (free)
Related: Proton Pump Inhibitors: Review of Emerging Concerns – Mayo Clinic Proceedings (free) AND Complications of Proton Pump Inhibitor Therapy – Gastroenterology (free) AND Adverse effects of proton-pump inhibitor use in older adults: a review of the evidence – Therapeutic Advances in Drug Safety (free) AND Deprescribing proton pump inhibitors: Evidence-based clinical practice guideline – Canadian Family Physician (free)
Source: Hospital Medicine Virtual Journal Club
Review: Management of Dyspnea in the Terminally Ill
24 Apr, 2018 | 18:03h | UTCManagement of Dyspnea in the Terminally Ill – CHEST (free PDF)
Source: Hospital Medicine Virtual Journal Club
Randomized Controlled Trial: Home vs Hospital Treatment of COPD Exacerbation
24 Apr, 2018 | 18:01h | UTCSource: Hospital Medicine Virtual Journal Club
Report: Role of Immunotherapy in the Treatment of Asthma
23 Apr, 2018 | 21:15h | UTCRole of Immunotherapy in the Treatment of Asthma – Agency for Healthcare Research and Quality (free)
Source: EvidenceAlerts
BTS Quality Standards for Acute Non-invasive Ventilation in Adults
20 Apr, 2018 | 01:32h | UTCRelated Guidelines: Clinical practice guidelines for the use of noninvasive positive-pressure ventilation and noninvasive continuous positive airway pressure in the acute care setting – Canadian Medical Association Journal (free) AND BTS/ICS guideline for the ventilatory management of acute hypercapnic respiratory failure in adults – Thorax (free)
Source: Critical Care Reviews Newsletter
Research: ECMO versus Prone Position in ARDS
20 Apr, 2018 | 00:51h | UTCUnproven and Expensive before Proven and Cheap: Extracorporeal Membrane Oxygenation versus Prone Position in Acute Respiratory Distress Syndrome – American Journal of Respiratory and Critical Care Medicine (link to abstract – $ for full-text)
Commentary: Few patients with ARDS in ECMO trials undergo prone positioning, though it saves lives – Univadis (free registration required)
Perspective: Smoking Even One Cigarette a Day Raises Risk for Coronary Heart Disease
18 Apr, 2018 | 01:11h | UTCSmoking even one cigarette a day raises risk for coronary heart disease – The Washington Post (a few articles per month are free) (via @DrFrieden see Tweet)
See original article: Meta-Analysis: Just One Cigarette a Day Seriously Elevates Cardiovascular Risk (free article and commentaries)
Meta-Analysis: Lung Ultrasound vs Chest Radiograph in Critically Ill Patients With Respiratory Symptoms
17 Apr, 2018 | 20:04h | UTCDiagnostic Accuracy of Chest Radiograph, and When Concomitantly Studied Lung Ultrasound, in Critically Ill Patients With Respiratory Symptoms: A Systematic Review and Meta-Analysis – Critical Care Medicine (link to abstract – $ for full-text)
Commentary: Lung ultrasound accuracy beats X-ray in critically ill patients with respiratory symptoms – Univadis (free registration required)
Report: State of Global Air 2018
18 Apr, 2018 | 00:59h | UTCState of Global Air 2018 (free report and interactive website)
Commentaries: Over 7 Billion People Face Unsafe Air: State of Global Air 2018 – Institute for Health Metrics and Evaluation (free) AND More than 95% of world’s population breathe dangerous air, major study finds – The Guardian (free) AND More than 95% of world’s population breathing unhealthy air, says new report – CNN (free)
Randomized Controlled Trial: Combination Therapy with Immunotherapy Increases Overall Survival in Patients with Lung Cancer
16 Apr, 2018 | 16:34h | UTCCommentaries: AACR 2018: Combination therapy doubles survival in metastatic lung cancer – eCancer News (free) AND Lung Cancer Patients Live Longer With Immune Therapy – New York Times (10 articles per month are free)
Case-crossover study: spikes in air pollution linked to increased risk of lower respiratory infections
14 Apr, 2018 | 18:22h | UTCShort-term Elevation of Fine Particulate Matter Air Pollution and Acute Lower Respiratory Infection – American Journal of Respiratory and Critical Care Medicine (link to abstract – $ for full-text)
Commentaries: Brief SExposure to Tiny Air Pollution Particles Triggers Childhood Lung Infections – Intermountain Medical Center, via NewsWise (free) AND Spikes in air pollution can heighten risk of chest infections, research suggests – The Guardian (free) AND Air Pollution May Pose Serious Risks to Young Children – The New York Times (10 articles per month are free) AND Short-Term Pollution Spikes Trigger Lung Infections in Young Kids – MedPage Today (free registration required)
AHA scientific statement: evaluation and management of right-sided heart failure
13 Apr, 2018 | 01:44h | UTCCommentary: Taking the Good With the Bad – Assigning Value and Blame to the Right Heart in Cardiovascular Disease (free)
Top Ten Things to Know: Evaluation and Management of Right-Sided Heart Failure (free PDF)
Research: the health, poverty, and financial consequences of a cigarette price increase
13 Apr, 2018 | 01:37h | UTCEditorial: The benefits of taxing cigarettes in middle income countries (free)
See also: To Improve Global Health, Tax the Things that are Killing Us (free policies, articles and commentaries) AND The Lancet Taskforce on NCDs and economics (free registration required for all articles and commentaries)
NCCN guideline: lung cancer screening
13 Apr, 2018 | 01:28h | UTCLung Cancer Screening, Version 3.2018, NCCN Clinical Practice Guidelines in Oncology (free)
See related guideline: Lung Cancer: Screening – U.S. Preventive Services Task Force (free)
Systematic review: honey for acute cough in children
12 Apr, 2018 | 02:33h | UTCHoney for acute cough in children – Cochrane Library (link to abstract – $ for full-text)
Summary: Honey for acute cough in children – Cochrane Library (free)
“Honey probably relieves cough symptoms to a greater extent than no treatment, diphenhydramine, and placebo, but may make little or no difference compared to dextromethorphan.”
Cohort study: childhood predictors of lung function trajectories and future COPD risk
12 Apr, 2018 | 02:04h | UTCChildhood predictors of lung function trajectories and future COPD risk: a prospective cohort study from the first to the sixth decade of life – The Lancet Respiratory Medicine (link to abstract – $ for full-text)
Related article: Lung function trajectories from pre-school age to adulthood and their associations with early life factors: a retrospective analysis of three population-based birth cohort studies – The Lancet Respiratory Medicine (link to abstract – $ for full-text)
Commentaries: Three-quarters of COPD cases are linked to childhood risk factors that are exacerbated in adulthood – The Lancet, via ScienceDaily (free) AND Early intervention may minimise later lung problems – The Melbourne Newsroom (free) AND COPD Risk Factors Evident Early in Life – NEJM Physician’s First Watch (free)
Randomized controlled trial: physiotherapy education before abdominal surgery reduces lung complications
12 Apr, 2018 | 01:16h | UTCPhysiotherapy education before major abdominal surgery reduces lung complications – NIHR Signal (free)
See original article: Preoperative physiotherapy for the prevention of respiratory complications after upper abdominal surgery: pragmatic, double blinded, multicentre randomised controlled trial – The BMJ (free)


