Chest Medicine
[Abstract Only] Randomized Trial: Similar Outcomes with Liberal vs. Conservative Oxygen Therapy for Acute Respiratory Distress Syndrome
12 Mar, 2020 | 08:20h | UTCLiberal or Conservative Oxygen Therapy for Acute Respiratory Distress Syndrome – New England Journal of Medicine (link to abstract – $ for full-text)
Visual Abstract: Oxygen Therapy in ARDS (free)
Related Randomized Trial: Similar Outcomes with Conservative Oxygen Therapy vs. Usual Oxygen Therapy During Mechanical Ventilation (link to abstract and commentaries)
Meta-Analysis: Perioperative Interventions for Prevention of Postoperative Pulmonary Complications
12 Mar, 2020 | 08:18h | UTC
“Less is More” in Mechanical Ventilation
12 Mar, 2020 | 08:12h | UTC“Less is More” in mechanical ventilation – Intensive Care Medicine (free)
ESA/ESICM Guideline: Noninvasive Respiratory Support in the Hypoxemic Peri-operative/Periprocedural Patient
8 Mar, 2020 | 20:44h | UTC
[Abstract Only] Adjunctive Strategies Underused in Moderate to Severe ARDS, International Study Finds
8 Mar, 2020 | 20:41h | UTCOriginal Study: Patterns of use of adjunctive therapies in patients with early moderate- severe Acute Respiratory Distress syndrome: Insights from the LUNG SAFE Study – CHEST (link to abstract – $ for full-text)
Meta-Analysis: T-piece vs. Pressure Support Ventilation as Spontaneous Breathing Trials in Critically Ill Patients
8 Mar, 2020 | 20:43h | UTC
Related Commentary on Twitter
#CritCare #OpenAccesshttps://t.co/bC8CLs77Hz#Mechanicalventilation is often required in critical patients, but several problems can impair the successful separation of the patient from the #ventilator#FOAMed #FOAMcc #BMC #CriticalCare #ICU #SBT #breathing #systematic #review pic.twitter.com/jDd5xp95Ru
— Critical Care (@Crit_Care) March 8, 2020
Coronavirus Disease 2019 (COVID-19): A Guide for UK GPs
6 Mar, 2020 | 10:27h | UTCCoronavirus disease 2019 (covid-19): a guide for UK GPs – The BMJ (free)
See also: Latest Research on the COVID-19 Outbreak (free resources)
Related Commentary on Twitter
When should you suspect covid-19 infection and what should you do?
This #BMJEducation article offers a practical guide for GPs and others working in UK primary care on when to suspect covid-19 and how to respond https://t.co/yFwSYw267F #COVID19
— The BMJ (@bmj_latest) March 6, 2020
8 Things to Know About E-cigarettes
6 Mar, 2020 | 10:25h | UTC8 things to know about e-cigarettes – Public Health Matters (free)
Related Report: Vaping in England: evidence update March 2020 – Public Health England (free)
FDA Safety Alert: Montelukast May Cause Serious Mental Health Side Effects
6 Mar, 2020 | 10:22h | UTCCommentary: Montelukast to Get Boxed Warning – NEJM Journal Watch (free)
[Abstract Only] Observational Study Suggests Flu Vaccine May Not Decrease Hospitalization or Mortality Among Elderly Persons
4 Mar, 2020 | 08:27h | UTCThe Effect of Influenza Vaccination for the Elderly on Hospitalization and Mortality: An Observational Study With a Regression Discontinuity Design – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentaries: Flu vaccine may not decrease hospitalization or mortality among elderly persons – American College of Physicians (free) AND Expert reaction to study looking at the flu vaccine and hospitalisation and mortality in older people – Science Media Centre (free) AND Isolated flu vaccination of elderly may not decrease hospitalization or mortality rates – ACP Internist (free)
State of the Art Review: Current and Future Treatments for Tuberculosis
3 Mar, 2020 | 07:59h | UTCCurrent and future treatments for tuberculosis – The BMJ (free for a limited period)
Related Commentary on Twitter
Tuberculosis is currently the leading cause of death globally from a single infectious agent. What is the current state of TB treatment and how might ongoing clinical trials change guidelines in the coming years? #BMJEducation https://t.co/U9gdkdrm5Y
— The BMJ (@bmj_latest) March 2, 2020
Podcast: Pulmonary Nodules and Lung Cancer Screening
3 Mar, 2020 | 07:34h | UTC
COVID-19—New Insights on a Rapidly Changing Epidemic
1 Mar, 2020 | 19:45h | UTCCOVID-19—New Insights on a Rapidly Changing Epidemic – JAMA (free)
See also: Latest Developments in the COVID-19 Outbreak (several resources on the subject)
Study: Clinical Characteristics of Coronavirus Disease 2019 in China
1 Mar, 2020 | 19:50h | UTCClinical Characteristics of Coronavirus Disease 2019 in China – New England Journal of Medicine (free)
Editorial: Covid-19 — Navigating the Uncharted – New England Journal of Medicine (free)
Related Commentaries: Responding to Covid-19 — A Once-in-a-Century Pandemic? – New England Journal of Medicine (free) AND Escaping Pandora’s Box — Another Novel Coronavirus – New England Journal of Medicine (free)
See also: Latest Developments in the COVID-19 Outbreak (several resources on the subject)
Essentials for Radiologists on COVID-19: An Update—Radiology Scientific Expert Panel
1 Mar, 2020 | 19:26h | UTCEssentials for Radiologists on COVID-19: An Update—Radiology Scientific Expert Panel – Radiology (free)
Related: COVID-19: Chest CT May be the Best Screening Tool for Diagnosis in Epidemic Areas (free studies on the subject) AND Radiological findings from 81 patients with COVID-19 pneumonia in Wuhan, China: a descriptive study – The Lancet Infectious Diseases (free) AND Imaging and clinical features of patients with 2019 novel coronavirus SARS-CoV-2 – European Journal of Nuclear Medicine and Molecular Imaging (free PDF) AND Chest CT Findings in Patients with Corona Virus Disease 2019 and its Relationship with Clinical Features – Investigative Radiology (free PDF) AND 2019 Novel Coronavirus (COVID-19) Pneumonia: Serial Computed Tomography Findings – Korean Journal of Radiology (free PDF) AND Chest Radiographic and CT Findings of the 2019 Novel Coronavirus Disease (COVID-19): Analysis of Nine Patients Treated in Korea – Korean Journal of Radiology (free PDF)
See also: Latest Developments and Research in the COVID-19 Outbreak (several resources on the subject)
Podcast: Airway Management of COVID-19
1 Mar, 2020 | 19:07h | UTCEMCrit Wee – Airway Management of COVID-19 (free audio)
Related: Practical recommendations for critical care and anesthesiology teams caring for novel coronavirus (2019-nCoV) patients – Canadian Journal of Anesthesia (free) AND Severe SARS-CoV-2 infections: practical considerations and management strategy for intensivists – Intensive Care Medicine (free) AND Coronavirus (2019-nCoV): evidence relevant to critical care – Cochrane Library (free articles) AND Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: a single-centered, retrospective, observational study – The Lancet Respiratory Medicine (free) AND Critical care response to a hospital outbreak of the 2019-nCoV infection in Shenzhen, China – Critical Care (free) AND Preparing for the Most Critically Ill Patients With COVID-19: The Potential Role of Extracorporeal Membrane Oxygenation – JAMA (free) AND Critical care management of adults with community-acquired severe respiratory viral infection – Intensive Care Medicine (free)
See also: Latest Developments in the COVID-19 Outbreak
Severe SARS-CoV-2 Infections: Practical Considerations and Management Strategy for Intensivists
27 Feb, 2020 | 08:36h | UTCRelated: Intensive care during the coronavirus epidemic – Intensive Care Medicine (free) AND How to face the novel coronavirus infection during the 2019–2020 epidemic: the experience of Sichuan Provincial People’s Hospital – Intensive Care Medicine (free) AND Critical care management of adults with community-acquired severe respiratory viral infection – Intensive Care Medicine (free) AND Coronavirus epidemic: preparing for extracorporeal organ support in intensive care – The Lancet Respiratory medicine (free) AND Preparing for the Most Critically Ill Patients With COVID-19: The Potential Role of Extracorporeal Membrane Oxygenation – JAMA (free)
Related Commentary on Twitter
Severe SARS-CoV-2 infections: practical considerations and management strategy for intensivists@yourICM #FOAMed https://t.co/E35YQ7wsyW pic.twitter.com/UWGokAFVJf
— Adrian Wong (@avkwong) February 26, 2020
COVID-19: Chest CT May be the Best Screening Tool for Diagnosis in Epidemic Areas
27 Feb, 2020 | 08:38h | UTCCommentary: CT provides best diagnosis for COVID-19 – Radiological Society of North America (free)
Related Articles: Sensitivity of Chest CT for COVID-19: Comparison to RT-PCR – Radiology (free) AND Coronavirus Outbreak: What the Department of Radiology Should Know – Journal of the American College of Radiology (free) AND Coronavirus Disease 2019 (COVID-19): A Perspective from China – Radiology (free) AND Chest CT Findings in Coronavirus Disease-19 (COVID-19): Relationship to Duration of Infection – Radiology (free) AND Outbreak of novel coronavirus (COVID-19): What is the role of radiologists? – European Radiology (free) AND Chest CT for Typical 2019-nCoV Pneumonia: Relationship to Negative RT-PCR Testing – Radiology (free) AND Pre- and Posttreatment Chest CT Findings: 2019 Novel Coronavirus (2019-nCoV) Pneumonia – Radiology (free)
Former CDC Director: A Coronavirus Pandemic is Inevitable. What Now?
26 Feb, 2020 | 07:06h | UTCFormer CDC director: A coronavirus pandemic is inevitable. What now? – CNN (free)
Related: Opinion on COVID-19 Outbreak – “Past Time to Tell the Public: “It Will Probably Go Pandemic, and We Should All Prepare Now”” (related opinions on the subject)
See also: Novel Coronavirus Disease (COVID-19) Latest Articles, Guidelines, News & Perspectives / 26 February 2020 Edition (free resources on the subject – updated daily)
Related Commentary on Twitter
#COVID19 will become a pandemic. We don’t know if it will be mild, moderate or severe, or how many countries it will reach. As we shift from the initiation phase of the pandemic to the acceleration stage, I’ve highlighted 8 things we must do for @CNN https://t.co/XAZx0jErbs
— Dr. Tom Frieden (@DrTomFrieden) February 25, 2020
Coronavirus Disease 2019 (COVID-19) Outbreak in China: Summary of a Report of 72 314 Cases from the Chinese Center for Disease Control and Prevention
25 Feb, 2020 | 06:46h | UTCCommentary: Study of 72,000 COVID-19 patients finds 2.3% death rate – CIDRAP (free)
Related Commentary on Twitter
The Chinese CDC today published the largest case series to date of #COVID19 in mainland China (72 314 cases through 2/11/20). Here are some of the data:
Case-fatality rate
• 2.3% Overall
• 14.8% age >= 80
• 8.0% age 70-79
• 49.0% in critical caseshttps://t.co/ZFR6pScCpa— JAMA (@JAMA_current) February 24, 2020
[Abstract Only] Meta-Analysis: Pharmacologic Therapies in Patients with Exacerbation of Chronic Obstructive Pulmonary Disease
25 Feb, 2020 | 06:36h | UTCPharmacologic Therapies in Patients With Exacerbation of Chronic Obstructive Pulmonary Disease: A Systematic Review With Meta-analysis – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentary: Meta-Analysis: Systemic Corticosteroids, Antibiotics Effective for COPD Exacerbations – NEJM Journal Watch (free)
Community-acquired Pneumonia in Critically Ill Very Old Patients: A Growing Problem
23 Feb, 2020 | 22:06h | UTCEditorial: Natural enemy or friend? Pneumonia in the very elderly critically ill patient (free)
Cohort Study: Frequent Use of Household Cleaning Products in Early Life Linked to Increased Risk for Childhood Wheeze and Asthma at Age 3 Years
23 Feb, 2020 | 21:44h | UTCCommentaries: Cleaning products and asthma risk: a potentially important public health concern – Canadian Medical Association Journal (free) AND Exposure to cleaning products linked to asthma and wheezing in children – Health Europa (free) AND Cleaning Products May Raise Risk of Wheezing and Asthma in Young Children – MedicalResearch.com (free)
Review: How Can We Minimize the Use of Regular Oral Corticosteroids in Asthma?
23 Feb, 2020 | 21:15h | UTCHow can we minimise the use of regular oral corticosteroids in asthma? – European Respiratory Review (free)
Review: α1-Antitrypsin Deficiency and Chronic Respiratory Disorders
23 Feb, 2020 | 21:16h | UTCα1-Antitrypsin deficiency and chronic respiratory disorders – European Respiratory Review (free)