Chest Medicine (all articles)
Former CDC Director: A Coronavirus Pandemic is Inevitable. What Now?
26 Feb, 2020 | 07:06h | UTCFormer CDC director: A coronavirus pandemic is inevitable. What now? – CNN (free)
Related: Opinion on COVID-19 Outbreak – “Past Time to Tell the Public: “It Will Probably Go Pandemic, and We Should All Prepare Now”” (related opinions on the subject)
See also: Novel Coronavirus Disease (COVID-19) Latest Articles, Guidelines, News & Perspectives / 26 February 2020 Edition (free resources on the subject – updated daily)
Related Commentary on Twitter
#COVID19 will become a pandemic. We don’t know if it will be mild, moderate or severe, or how many countries it will reach. As we shift from the initiation phase of the pandemic to the acceleration stage, I’ve highlighted 8 things we must do for @CNN https://t.co/XAZx0jErbs
— Dr. Tom Frieden (@DrTomFrieden) February 25, 2020
Coronavirus Disease 2019 (COVID-19) Outbreak in China: Summary of a Report of 72 314 Cases from the Chinese Center for Disease Control and Prevention
25 Feb, 2020 | 06:46h | UTCCommentary: Study of 72,000 COVID-19 patients finds 2.3% death rate – CIDRAP (free)
Related Commentary on Twitter
The Chinese CDC today published the largest case series to date of #COVID19 in mainland China (72 314 cases through 2/11/20). Here are some of the data:
Case-fatality rate
• 2.3% Overall
• 14.8% age >= 80
• 8.0% age 70-79
• 49.0% in critical caseshttps://t.co/ZFR6pScCpa— JAMA (@JAMA_current) February 24, 2020
[Abstract Only] Meta-Analysis: Pharmacologic Therapies in Patients with Exacerbation of Chronic Obstructive Pulmonary Disease
25 Feb, 2020 | 06:36h | UTCPharmacologic Therapies in Patients With Exacerbation of Chronic Obstructive Pulmonary Disease: A Systematic Review With Meta-analysis – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentary: Meta-Analysis: Systemic Corticosteroids, Antibiotics Effective for COPD Exacerbations – NEJM Journal Watch (free)
Community-acquired Pneumonia in Critically Ill Very Old Patients: A Growing Problem
23 Feb, 2020 | 22:06h | UTCEditorial: Natural enemy or friend? Pneumonia in the very elderly critically ill patient (free)
Cohort Study: Frequent Use of Household Cleaning Products in Early Life Linked to Increased Risk for Childhood Wheeze and Asthma at Age 3 Years
23 Feb, 2020 | 21:44h | UTCCommentaries: Cleaning products and asthma risk: a potentially important public health concern – Canadian Medical Association Journal (free) AND Exposure to cleaning products linked to asthma and wheezing in children – Health Europa (free) AND Cleaning Products May Raise Risk of Wheezing and Asthma in Young Children – MedicalResearch.com (free)
Review: How Can We Minimize the Use of Regular Oral Corticosteroids in Asthma?
23 Feb, 2020 | 21:15h | UTCHow can we minimise the use of regular oral corticosteroids in asthma? – European Respiratory Review (free)
Review: α1-Antitrypsin Deficiency and Chronic Respiratory Disorders
23 Feb, 2020 | 21:16h | UTCα1-Antitrypsin deficiency and chronic respiratory disorders – European Respiratory Review (free)
Meta-Analysis: ALK Inhibitors for Non-small Cell Lung Cancer
21 Feb, 2020 | 10:33h | UTC
Global Burden of Disease Study: Trends and Risk Factors of Mortality and Disability-Adjusted Life Years for Chronic Respiratory Diseases
20 Feb, 2020 | 11:00h | UTCCommentary: Sharp rise in lung disease deaths over past 27 years – OnMedica (free)
Related Commentary on Twitter
There has been an increase in deaths and disability due to chronic respiratory (lung) diseases over the past three decades, finds an analysis of data from 195 countries #BMJResearch https://t.co/FEmeZ5JjEI
— The BMJ (@bmj_latest) February 20, 2020
Study: Vitamin E Acetate in Bronchoalveolar-Lavage Fluid Associated with EVALI (E-Cigarette, or Vaping, Product Use–Associated Lung Injury)
20 Feb, 2020 | 10:22h | UTCVideo Summary: Vitamin E Acetate Associated with EVALI (free)
Related Report: Syndromic Surveillance for E-Cigarette, or Vaping, Product Use–Associated Lung Injury – new England Journal of Medicine (free)
See also: The EVALI and Youth Vaping Epidemics — Implications for Public Health – New England Journal of Medicine (free) AND CDC: Vaping Lung Illness Probably Caused by Vitamin E Acetate (free resources)
[Abstract Only] Meta-Analysis: Clinical Pre‐test Probability Adjusted vs. Age‐adjusted D‐dimer Interpretation Strategy for DVT Diagnosis
20 Feb, 2020 | 08:36h | UTCClinical pre‐test probability adjusted versus age‐adjusted D‐dimer interpretation strategy for DVT diagnosis: A diagnostic individual patient data meta‐analysis – Journal of Thrombosis and Haemostasis (link to abstract – $ for full-text)
Commentary: Clinical Pre-test Prob vs. Age-adjusted D-dimer for DVT – The Meta Analysis – JournalFeed (free)
Related Studies: Diagnosis of Pulmonary Embolism with d-Dimer Adjusted to Clinical Probability – New England Journal of Medicine (link to abstract and commentary) AND Age-Adjusted D-Dimer Cutoff Levels to Rule Out Pulmonary Embolism: The ADJUST-PE Study – JAMA (free)
China Releases Largest Study on COVID-19 Outbreak with Over 44.000 Patients – Elderly and Sick are Most at Risk
19 Feb, 2020 | 10:23h | UTCThe Epidemiological Characteristics of an Outbreak of 2019 Novel Coronavirus Diseases (COVID-19) – China, 2020 – China CDC Weekly (free PDF – link via Forbes)
Commentaries: Coronavirus: Largest study suggests elderly and sick are most at risk – BBC (free) AND New Chinese Study Finds That The Elderly Are Most At Risk From The Coronavirus [Infographic] – Forbes (free) AND Expert reaction to WHO Director General’s statement on new paper from China detailing over 44,000 of their cases – Science Media Centre (free)
Guideline Synopsis: Management of Chronic Insomnia Disorder and Obstructive Sleep Apnea
18 Feb, 2020 | 08:25h | UTCCommentary: New VA/DoD guidelines address sleep-related issues in military personnel, veterans – University of Texas Health Science Center at San Antonio (free)
Observational Study: Empirical Anti-MRSA Antibiotic Therapy Does Not Improve Outcomes in Patients Hospitalized for Pneumonia
18 Feb, 2020 | 08:15h | UTCEmpirical Anti-MRSA vs Standard Antibiotic Therapy and Risk of 30-Day Mortality in Patients Hospitalized for Pneumonia – JAMA Internal Medicine (free for a limited period)
Editorial: Overuse of Broad-Spectrum Antibiotics for Pneumonia (free for a limited period)
Related Commentary on Twitter
NEW ?⚡Retrospective multicenter cohort study @JAMA_current
Empirical Anti-MRSA vs Standard Antibiotic Therapy and Risk of 30-Day Mortality in Patients Hospitalized for Pneumonia. #IDTwitter #medtwitter https://t.co/X0jWhMaUMT pic.twitter.com/FwNadOZrjx— Antibiotic Steward ? (@ABsteward) February 17, 2020
Meta-Analysis: Subglottic Secretion Drainage for Preventing Ventilator-associated Pneumonia
18 Feb, 2020 | 08:01h | UTC
Current and Future Applications of Liquid Biopsy in Nonsmall Cell Lung Cancer from Early to Advanced Stages
18 Feb, 2020 | 08:02h | UTC
Extracorporeal Membrane Oxygenation for Refractory Cardiac Arrest: A Retrospective Multicenter Study
16 Feb, 2020 | 21:02h | UTC
Basic Point‐of‐care Ultrasound Framework Based on the Airway, Breathing, and Circulation Approach for the Initial Management of Shock and Dyspnea
16 Feb, 2020 | 20:46h | UTCSource: Grupo UTIclínica – HCFMUSP
CDC Guidelines for the Treatment of Latent Tuberculosis Infection
14 Feb, 2020 | 02:22h | UTCRelated: WHO Guideline: Latent TB Infection (free) AND Study: Rifampicin is Likely to be the Safest Latent Tuberculosis Infection Treatment Option (free)
Commentary: Guidelines Updated on Treating Latent TB – NEJM Journal Watch (free)
Clinical Updates: Management of Acute and Chronic Asthma in Adults in 2020
14 Feb, 2020 | 02:06h | UTCManagement of Acute Asthma in Adults in 2020 – JAMA (free for a limited period)
Related Article: Outpatient Management of Chronic Asthma in 2020 – JAMA (free for a limited period)
Editorial: New Therapeutic Strategies for Asthma – JAMA (free for a limited period)
[Abstract Only] Randomized Trial: Plasma Exchange and Glucocorticoids in Severe ANCA-Associated Vasculitis
13 Feb, 2020 | 08:00h | UTCPlasma Exchange and Glucocorticoids in Severe ANCA-Associated Vasculitis – New England Journal of Medicine (link to abstract – $ for full-text)
Visual Abstract: Plasma Exchange and Glucocorticoids for ANCA-Associated Vasculitis (free)
Commentary: PEXIVAS: No benefit of plasma exchange in ANCA-associated vasculitis – Medicine Matters (free)
[Abstract Only] Randomized Trial: Dexamethasone for the Treatment of Acute Respiratory Distress Syndrome
12 Feb, 2020 | 07:24h | UTCDexamethasone treatment for the acute respiratory distress syndrome: a multicentre, randomised controlled trial – The Lancet Respiratory Medicine (link to abstract – $ for full-text)
Related: Meta-Analysis: Assessment of Therapeutic Interventions and Lung Protective Ventilation in Patients with Moderate to Severe Acute Respiratory Distress Syndrome (free resources on the subject)
Related Commentary on Twitter
#Dexamethasone is associated with a substantial reduction in duration of mechanical #ventilation and all-cause 60-day #mortality in patients with #ARDS
New RCT from Jesús ViIlar and colleagues https://t.co/b4sW2K0RwG pic.twitter.com/MBbeSWBo55
— The Lancet Respiratory Medicine (@LancetRespirMed) February 10, 2020
Critical Care Management of Adults with Community-acquired Severe Respiratory Viral Infection
11 Feb, 2020 | 02:25h | UTC
Systematic Review: Schistosomiasis-associated Pulmonary Arterial Hypertension
11 Feb, 2020 | 01:59h | UTC
Clinical Controversies in Anticoagulation Monitoring and Antithrombin Supplementation for ECMO
11 Feb, 2020 | 01:44h | UTC