Chest Medicine (all articles) | Page 131 of 169 | Links Medicus Content Curation & Alerts in Medicine

Loss of Smell and Taste Could be a Sign of COVID-19

23 Mar, 2020 | 01:11h | UTC

Position Statement: Loss of sense of smell as marker of COVID-19 infection – ENT-UK

IDSA Statement: COVID-19 Prioritization of Diagnostic Testing

20 Mar, 2020 | 11:01h | UTC

COVID-19 Prioritization of Diagnostic Testing – Infectious Diseases Society of America (free PDF)

Summary: IDSA Statement On COVID-19 Testing Recommendations – Infectious Diseases Society of America (free)

Editorial by John P.A. Ioannidis: COVID-19: The Harms of Exaggerated Information and Non‐evidence‐based Measures

23 Mar, 2020 | 01:08h | UTC

Coronavirus disease 2019: the harms of exaggerated information and non‐evidence‐based measures – European Journal of Clinical Investigation (free PDF)

Rebuttal 1: We know enough now to act decisively against Covid-19. Social distancing is a good place to start – STAT (free)

Rebuttal 2: A Rebuttal to “A Fiasco in the Making?” – Hilda Bastian (Free)

New Preliminary Studies with Hydroxychloroquine:

20 Mar, 2020 | 10:57h | UTC

Hydroxychloroquine and azithromycin as a treatment of COVID-19: results of an open label non-randomized clinical trial – International Journal of Antimicrobial Agents (free PDF)

This was an open-label study with only 42 patients without patient-relevant endpoints. The 6 patients that received Hydroxychloroquine + Azithromycin achieved more efficient virus elimination than control patients.

New in Vitro Study: Hydroxychloroquine, a less toxic derivative of chloroquine, is effective in inhibiting SARS-CoV-2 infection in vitro – Cell Discovery (free)

CDC Guideline: Strategies for Optimizing the Supply of Facemasks

20 Mar, 2020 | 11:03h | UTC

Strategies for Optimizing the Supply of Facemasks – Centers for Disease Control and Prevention (free)

Video: Coronavirus Update with Anthony Fauci, MD

19 Mar, 2020 | 11:04h | UTC

Coronavirus Update with Anthony Fauci, MD – March 18, 2020 – JAMA (free)

Podcast: New Research on Possible Treatments for Covid-19

19 Mar, 2020 | 10:57h | UTC

Interview with Dr. Eric Rubin and Dr. Lindsey Baden on new research on possible treatments for Covid-19 – New England Journal of Medicine (free)

State of the Art Review: Management of ANCA Associated Vasculitis

19 Mar, 2020 | 10:54h | UTC

Management of ANCA associated vasculitis – The BMJ (free)

Interim Guidance: Clinical Management of Severe Acute Respiratory Infection When Novel Coronavirus (nCoV) Infection is Suspected

16 Mar, 2020 | 08:01h | UTC

Clinical management of severe acute respiratory infection when novel coronavirus (nCoV) infection is suspected – World Health Organization (free PDF)

Related Commentary on Twitter

Updated #COVID19 clinical guidance covers:
?Early case recognition
?Guidance for care of children, pregnant women, adults & older people
?Managing cases
?Infection prevention & control
?Sample collection & an update on investigational therapeutics
?https://t.co/ZVaiu2C19V pic.twitter.com/yyOzIbtbEO

— World Health Organization (WHO) (@WHO) March 15, 2020

Critical Care Utilization for the COVID-19 Outbreak in Lombardy, Italy: Early Experience and Forecast During an Emergency Response

16 Mar, 2020 | 07:55h | UTC

Critical Care Utilization for the COVID-19 Outbreak in Lombardy, Italy: Early Experience and Forecast During an Emergency Response – JAMA (free)

[Abstract Only] Randomized Trial: Similar Outcomes with Liberal vs. Conservative Oxygen Therapy for Acute Respiratory Distress Syndrome

12 Mar, 2020 | 08:20h | UTC

Liberal or Conservative Oxygen Therapy for Acute Respiratory Distress Syndrome – New England Journal of Medicine (link to abstract – $ for full-text)

Visual Abstract: Oxygen Therapy in ARDS (free)

Related Randomized Trial: Similar Outcomes with Conservative Oxygen Therapy vs. Usual Oxygen Therapy During Mechanical Ventilation (link to abstract and commentaries)

Meta-Analysis: Perioperative Interventions for Prevention of Postoperative Pulmonary Complications

12 Mar, 2020 | 08:18h | UTC

Perioperative interventions for prevention of postoperative pulmonary complications: systematic review and meta-analysis – The BMJ (free)

“Less is More” in Mechanical Ventilation

12 Mar, 2020 | 08:12h | UTC

“Less is More” in mechanical ventilation – Intensive Care Medicine (free)

ESA/ESICM Guideline: Noninvasive Respiratory Support in the Hypoxemic Peri-operative/Periprocedural Patient

8 Mar, 2020 | 20:44h | UTC

Noninvasive respiratory support in the hypoxaemic peri-operative/periprocedural patient: A joint ESA/ESICM guideline – European Journal of Anaesthesiology (free)

[Abstract Only] Adjunctive Strategies Underused in Moderate to Severe ARDS, International Study Finds

8 Mar, 2020 | 20:41h | UTC

Adjunctive strategies underused in moderate to severe ARDS, international study finds – ACP Internist (free)

Original Study: Patterns of use of adjunctive therapies in patients with early moderate- severe Acute Respiratory Distress syndrome: Insights from the LUNG SAFE Study – CHEST (link to abstract – $ for full-text)

Meta-Analysis: T-piece vs. Pressure Support Ventilation as Spontaneous Breathing Trials in Critically Ill Patients

8 Mar, 2020 | 20:43h | UTC

Comparison of T-piece and pressure support ventilation as spontaneous breathing trials in critically ill patients: a systematic review and meta-analysis – Critical Care (free)

Related Commentary on Twitter

#CritCare #OpenAccess https://t.co/bC8CLs77Hz #Mechanicalventilation is often required in critical patients, but several problems can impair the successful separation of the patient from the #ventilator #FOAMed #FOAMcc #BMC #CriticalCare #ICU #SBT #breathing #systematic #review pic.twitter.com/jDd5xp95Ru

— Critical Care (@Crit_Care) March 8, 2020

Coronavirus Disease 2019 (COVID-19): A Guide for UK GPs

6 Mar, 2020 | 10:27h | UTC

Coronavirus disease 2019 (covid-19): a guide for UK GPs – The BMJ (free)

See also: Latest Research on the COVID-19 Outbreak (free resources)

Related Commentary on Twitter

When should you suspect covid-19 infection and what should you do?

This #BMJEducation article offers a practical guide for GPs and others working in UK primary care on when to suspect covid-19 and how to respond https://t.co/yFwSYw267F #COVID19

— The BMJ (@bmj_latest) March 6, 2020

8 Things to Know About E-cigarettes

6 Mar, 2020 | 10:25h | UTC

8 things to know about e-cigarettes – Public Health Matters (free)

FDA Safety Alert: Montelukast May Cause Serious Mental Health Side Effects

6 Mar, 2020 | 10:22h | UTC

FDA requires Boxed Warning about serious mental health side effects for asthma and allergy drug montelukast (Singulair); advises restricting use for allergic rhinitis – U.S. Food & Drug Administration (free)

Commentary: Montelukast to Get Boxed Warning – NEJM Journal Watch (free)

[Abstract Only] Observational Study Suggests Flu Vaccine May Not Decrease Hospitalization or Mortality Among Elderly Persons

4 Mar, 2020 | 08:27h | UTC

The Effect of Influenza Vaccination for the Elderly on Hospitalization and Mortality: An Observational Study With a Regression Discontinuity Design – Annals of Internal Medicine (link to abstract – $ for full-text)

Commentaries: Flu vaccine may not decrease hospitalization or mortality among elderly persons – American College of Physicians (free) AND Expert reaction to study looking at the flu vaccine and hospitalisation and mortality in older people – Science Media Centre (free) AND Isolated flu vaccination of elderly may not decrease hospitalization or mortality rates – ACP Internist (free)

State of the Art Review: Current and Future Treatments for Tuberculosis

3 Mar, 2020 | 07:59h | UTC

Current and future treatments for tuberculosis – The BMJ (free for a limited period)

Related Commentary on Twitter

Tuberculosis is currently the leading cause of death globally from a single infectious agent. What is the current state of TB treatment and how might ongoing clinical trials change guidelines in the coming years? #BMJEducation https://t.co/U9gdkdrm5Y

— The BMJ (@bmj_latest) March 2, 2020