Chest Medicine
Study: Convalescent Plasma Therapy in Severe COVID-19 Patients
7 Apr, 2020 | 04:14h | UTCRelated Studies: Treatment with convalescent plasma for critically ill patients with SARS-CoV-2 infection – CHEST AND Treatment of 5 Critically Ill Patients With COVID-19 With Convalescent Plasma – JAMA
COVID-19: More Opinions on Hydroxychloroquine
7 Apr, 2020 | 04:17h | UTCHydroxychloroquine Update For April 6 – Science Translational Medicine
The Debacle of Hydroxychloroquine and Azithromycin for COVID19 – Dr. John M.
Summary: wait for proper studies before prescribing.
Richard Lehman’s Covid-19 Reviews—6 April 2020
7 Apr, 2020 | 04:16h | UTCRichard Lehman’s covid-19 reviews, 6 April 2020 – The BMJ Opinion
In this weekly round-up, Richard Lehman looks at a personal selection of articles of relevance to clinicians dealing with covid-19.
NICE Publishes new COVID-19 Guidelines
6 Apr, 2020 | 01:57h | UTC- News Release: NICE publishes new COVID-19 guidelines on severe asthma, pneumonia, rheumatological disorders and symptom management – National Institute for Health and Care Excellence
- COVID-19 rapid guideline: severe asthma
- COVID-19 rapid guideline: managing suspected or confirmed pneumonia in adults in the community
- COVID-19 rapid guideline: rheumatological autoimmune, inflammatory and metabolic bone disorders
- COVID-19 rapid guideline: managing symptoms (including at the end of life) in the community
See other recent NICE Guidelines on COVID-19: COVID-19 rapid guideline: critical care in adults AND COVID-19 rapid guideline: haematopoietic stem cell transplantation AND COVID-19 rapid guideline: dialysis service delivery AND COVID-19 rapid guideline: delivery of radiotherapy AND COVID-19 rapid guideline: delivery of systemic anticancer treatments
Study: Wearing Surgical Masks in Public Could Help Slow Spreading of COVID-19
6 Apr, 2020 | 01:55h | UTCRespiratory virus shedding in exhaled breath and efficacy of face masks – Nature
Commentaries: Why wear face masks in public? Here’s what the research shows – The Conversation AND The new coronavirus might spread when people talk, but scientists say masks can help – The Telegraph AND Wearing surgical masks in public could help slow COVID-19 pandemic’s advance – University of Maryland
Related: Stability of SARS-CoV-2 in different environmental conditions – National Geographic
CDC Now Recommends Wearing Cloth Face Coverings in Public Settings
6 Apr, 2020 | 01:53h | UTCCommentaries: The CDC Now Recommends Americans Wear Face Masks – Wired AND Everyone should wear face ‘masks’ in public, CDC now recommends – Live Science AND CDC Now Recommends Americans Consider Wearing Cloth Face Coverings In Public – NPR AND The CDC now recommends everyone use cloth masks in public – Vox AND The CDC is recommending that people wear face coverings or cloth masks if they go out in public – Business Insider
“CDC recommends wearing cloth face coverings in public settings where other social distancing measures are difficult to maintain (e.g., grocery stores and pharmacies) especially in areas of significant community-based transmission.”
CDC Guideline: Use of Cloth Face Coverings to Help Slow the Spread of COVID-19
6 Apr, 2020 | 01:51h | UTCCommentary: What’s the Best Material for a Mask? – The New York Times
Study: No Benefit from Hydroxychloroquine and Azithromycin in Patients with Severe COVID-19 Infection
6 Apr, 2020 | 01:46h | UTC
COVID-19: Thrombosis, Coagulopathy and Disseminated Intravascular Coagulation
6 Apr, 2020 | 01:42h | UTCGuidelines: Practical guidance for the prevention of thrombosis and management of coagulopathy and disseminated intravascular coagulation of patients infected with COVID-19 – Thrombosis UK AND ISTH interim guidance on recognition and management of coagulopathy – Journal of Thrombosis and Haemostasis
Observational Studies: Anticoagulant treatment is associated with decreased mortality in severe coronavirus disease 2019 patients with coagulopathy – Journal of Thrombosis and Haemostasis AND Abnormal Coagulation parameters are associated with poor prognosis in patients with novel coronavirus pneumonia – Journal of Thrombosis and Haemostasis (free PDF)
Q & A: COVID-19 and Coagulopathy: Frequently Asked Questions – American Society of Hematology
COVID-19 Pneumonia: Different Respiratory Treatment for Different Phenotypes?
6 Apr, 2020 | 01:40h | UTC
Opinion: Covid-19 Does Not Lead to a “Typical” Acute Respiratory Distress Syndrome
3 Apr, 2020 | 04:14h | UTC“After considering that, all we can do ventilating these patients is “buying time” with minimum additional damage: the lowest possible PEEP and gentle ventilation. We need to be patient.”
Guide to Lung Ultrasound in COVID-19 Patients
3 Apr, 2020 | 04:02h | UTCComplete GUIDE to Lung Ultrasound in COVID-19 (Coronavirus) Patients – POCUS 101
Related: Proposal for international standardization of the use of lung ultrasound for COVID‐19 patients; a simple, quantitative, reproducible method – Journal of Ultrasound in Medicine AND Findings of lung ultrasonography of novel corona virus pneumonia during the 2019–2020 epidemic – Intensive Care Medicine AND Can Lung US Help Critical Care Clinicians in the Early Diagnosis of Novel Coronavirus (COVID-19) Pneumonia? – Radiology AND Point-of-Care Lung Ultrasound findings in novel coronavirus disease-19 pnemoniae: a case report and potential applications during COVID-19 outbreak – European Review for Medical and Pharmacological Sciences AND ACEP Guideline on COVID-19: Ultrasound Machine and Transducer Cleaning
CDC Guidance: Decontamination and Reuse of Filtering Facepiece Respirators
2 Apr, 2020 | 04:24h | UTC
Use of Hydroxychloroquine and Chloroquine During the COVID-19 Pandemic: What Every Clinician Should Know
2 Apr, 2020 | 04:21h | UTC
Evidence Review: In Patients of COVID-19, what Are the Symptoms and Clinical Features of Mild and Moderate Cases?
2 Apr, 2020 | 04:16h | UTCSee also: Other Reviews at Oxford COVID-19 Evidence Service
Use of Face Masks by the Population: The Debate Continues
2 Apr, 2020 | 04:04h | UTC- Everyone Thinks They’re Right About Masks – The Atlantic
- COMMENTARY: Masks-for-all for COVID-19 not based on sound data – CIDRAP
- You Still Probably Don’t Need A Mask For COVID-19 – Medium
- Everything you need to know about making your own face mask – Vox
- All Israelis must wear face-masks in public as virus precaution: Netanyahu – Reuters
- C.D.C. Weighs Advising Everyone to Wear a Mask – The New York Times
Pandemic Palliative Care: Beyond Ventilators and Saving Lives
1 Apr, 2020 | 05:55h | UTCPandemic palliative care: beyond ventilators and saving lives – Canadian Medical Association Journal
Commentary: A COVID-19 palliative care pandemic plan: An essential tool – Canadian Medical Association Journal
Related: The Importance of Addressing Advance Care Planning and Decisions About Do-Not-Resuscitate Orders During Novel Coronavirus 2019 (COVID-19) – JAMA AND Covid-19: The role of palliative care had to be adapted to manage this “ultra-emergency” – The BMJ Opinion AND COVID-19: decision making and palliative care – Swiss Medical Weekly AND COVID-19 pandemic: palliative care for elderly and frail patients at home and in residential and nursing homes – Swiss Medical Weekly AND End-of-life care in the Emergency Department for the patient imminently dying of a highly transmissible acute respiratory infection (such as COVID-19) – Canadian Journal of Emergency Medicine
‘Panic Prescribing’ Untested Coronavirus Treatments
1 Apr, 2020 | 05:51h | UTC- ‘Panic Prescribing’ Untested Coronavirus Treatments: A Danger To Patients Today and Tomorrow – Health Affairs
- We shouldn’t rush to use an unproven malaria drug to treat the coronavirus – STAT
- See also: Twitter Thread on the Latest Study Testing Hydroxychloroquine, by Lucas Morin
U.S. Prevalence of Underlying Health Conditions Among Patients with COVID-19
1 Apr, 2020 | 05:45h | UTCCommentaries: More than 70% of Americans hospitalized with COVID-19 had at least 1 underlying health condition, the CDC says — here’s the breakdown – Business Insider AND People With Underlying Health Conditions Are At Risk Of More Severe COVID-19, Says New CDC Report – Forbes AND Who’s Sickest From COVID-19? These Conditions Tied To Increased Risk – NPR
[Preprint] COVID-19: Hydroxychloroquine Beneficial in Small Trial
31 Mar, 2020 | 04:51h | UTC
JAMA Guideline Synopsis: Management of Critically Ill Adults With COVID-19
30 Mar, 2020 | 02:17h | UTCManagement of Critically Ill Adults With COVID-19 – JAMA
Editorial: Toward Universal Deployable Guidelines for the Care of Patients With COVID-19
Original Guideline: Surviving Sepsis Campaign: Guidelines on the Management of Critically Ill Adults with Coronavirus Disease 2019 (COVID-19) – Intensive Care Medicine
Related Summary: Surviving Sepsis Campaign: COVID-19 Recommendations – CanadiEm
Related Guideline: COVID-19 rapid guideline: critical care – National Institute for Health and Care Excellence
NICE Guideline: Venous Thromboembolic Diseases
30 Mar, 2020 | 02:27h | UTC
Primary Care & Coronavirus (COVID 19): Key Guidance, Information and Support
30 Mar, 2020 | 01:45h | UTCPrimary care & Coronavirus (COVID 19): key guidance, information and support – Medium
Related: Coronavirus disease 2019 (covid-19): a guide for UK GPs – The BMJ AND Covid-19: a remote assessment in primary care – The BMJ
Related Commentary on Twitter
I've written a blog for primary care on #coronavirus:
🗣️ Preparing, comms, diagnosis
📞 Remote consulting
😷 PPE
💊 Coding/meds
👨👨👦👦 Pt resources
🏥 Clinical advice for diff groups/ways of working
🌍 General resources
🛏️ Professional support— Dipesh Gopal (@DipeshGopal) March 28, 2020
#ACC20 – [Abstract Only] Apixaban for the Treatment of Venous Thromboembolism Associated with Cancer
30 Mar, 2020 | 01:12h | UTCApixaban for the Treatment of Venous Thromboembolism Associated with Cancer – New England Journal of Medicine (abstract Only – $ for full-text)
Commentaries: Caravaggio Trial: Apixaban Noninferior to Dalteparin in Treatment of Cancer-Associated VTE – American College of Cardiology (free) AND Apixaban, Dalteprin Shown to Have Same Bleeding Risk in Patients With Cancer – AJMC (free)
Just Presented at the 2020 American College of Cardiology Virtual Meeting (free access)
Must-see Video! Perspectives on the Pandemic with Dr. John Ioannidis
27 Mar, 2020 | 04:03h | UTCPerspectives on the Pandemic with Dr. John Ioannidis
Related Article: Editorial by John P.A. Ioannidis: COVID-19: The Harms of Exaggerated Information and Non‐evidence‐based Measures (free study and commentaries)