Chest Medicine
New Study Does Not Support the Idea that BCG Vaccination Protects Against COVID-19
14 May, 2020 | 10:12h | UTCSARS-CoV-2 Rates in BCG-Vaccinated and Unvaccinated Young Adults – JAMA
Related: BCG Against Coronavirus: Less Hype And More Evidence, Please – Forbes AND Does BCG vaccination protect against acute respiratory infections and COVID-19? A rapid review of current evidence – CEBM University of Oxford AND Bacille Calmette-Guérin (BCG) vaccination and COVID-19 – World Health Organization
Review: Pulmonary Complications Associated with Veno-arterial ECMO
14 May, 2020 | 02:22h | UTC
ERS Guideline: Withdrawal of Inhaled Corticosteroids in COPD
14 May, 2020 | 02:17h | UTC
Research Round-up: COPD
14 May, 2020 | 02:20h | UTCResearch round-up: COPD – Nature
Related: Should physicians still be prescribing steroid inhalers as a first-line treatment for COPD? – Nature AND Redefining the diagnostic criteria for COPD – Nature
See other articles from the series: Nature Outlook on COPD
Cohort Study: Pulmonary Rehabilitation Linked to Improved Survival After Hospitalization for COPD
14 May, 2020 | 02:14h | UTCAssociation Between Initiation of Pulmonary Rehabilitation After Hospitalization for COPD and 1-Year Survival Among Medicare Beneficiaries – JAMA (free for a limited period)
Editorial: Pulmonary Rehabilitation and Improved Survival for Patients With COPD (free for a limited period)
Interpreting a Covid-19 Test Result
13 May, 2020 | 02:18h | UTCPractice Pointer: Interpreting a covid-19 test result – The BMJ
Related: Interpreting Diagnostic Tests for SARS-CoV-2 – JAMA
New Clinical Risk Score to Predict the Occurrence of Critical Illness in Hospitalized Patients With COVID-19
13 May, 2020 | 02:14h | UTCSee also: Calculation Tool For Predicting Critical-ill COVID-19 At Admission
Related Preprint Study (just published): Development and validation of the COVID-19 severity index (CSI): a prognostic tool for early respiratory decompensation – medRxiv AND Calculation Tool: https://covidseverityindex.org/
Study Commentary – Virus Wars: Return of Lopinavir/Ritonavir (Along with Ribavirin and Interferon)
13 May, 2020 | 02:12h | UTCVirus Wars: Return of Lopinavir/Ritonavir (along with ribavirin and interferon) – PulmCrit
Original Article: Triple Therapy Antiviral Combination Seems Promising for COVID-19 in Open-label, Randomized, Phase 2 Trial (study and commentaries)
Hydroxychloroquine in Patients with COVID-19: A Systematic Review and Meta-analysis
13 May, 2020 | 01:53h | UTC“While initial studies with hydroxychloroquine showed some ray of hope, recent studies that have emerged found either no benefit or a possible harm in COVID-19.”
Remdesivir in COVID-19: A Critical Review of Pharmacology, Pre-clinical and Clinical Studies
13 May, 2020 | 01:50h | UTC“While the first double-blind, randomized-controlled trial (DBRCT) found no significant benefit with remdesivir compared to placebo, preliminary reports from another DBRCT showed a significant faster recovery, without any difference in mortality.”
The FDA has Authorized the use of Remdesivir: But There’s no Good Evidence it Reduces Mortality in Covid-19
13 May, 2020 | 01:49h | UTC
Observational Study: Hydroxychloroquine, Azithromycin, or Both Not Associated with Lower In-hospital Mortality
12 May, 2020 | 03:39h | UTC
Coagulation Abnormalities and Thrombosis in Patients with COVID-19
12 May, 2020 | 03:16h | UTCCoagulation abnormalities and thrombosis in patients with COVID-19 – The Lancet
Related Commentary on Twitter
Good to see these welcome recommendations today for diagnosis of clotting and its prevention in patients with severe #COVID19 @TheLancetHaem https://t.co/RrtXSIu2Ne by @MarcelLevi @JerroldLevy and colleagues pic.twitter.com/dU17RIj1f2
— Eric Topol (@EricTopol) May 11, 2020
Perspective: Which COVID-19 Antivirals Actually Work?
12 May, 2020 | 03:18h | UTCPerspective: Which COVID-19 Antivirals Actually Work? – Forbes
Related: Hong Kong Doctors See Progress In Treatment Of COVID-19 – Forbes
Frequency of Medical Reversal Among Published Randomized Controlled Trials Assessing Cardiopulmonary Resuscitation
12 May, 2020 | 03:08h | UTCRelated: Medical Reversals in Family Practice: A Review – Current Therapeutic Research AND Meta-Research: A Comprehensive Review of Randomized Trials Leading to “Medical Reversals” in Three Medical Journals
Triple Therapy Antiviral Combination Seems Promising for COVID-19 in Open-label, Randomized, Phase 2 Trial
11 May, 2020 | 00:42h | UTCCommentaries: Interferon beta-1b for COVID-19 – The Lancet AND New triple antiviral drug combination shows early promise for treating COVID-19 in phase 2 randomized trial – The Lancet AND A Drug Cocktail Hastens Recovery in Some Coronavirus Patients – The New York Times AND Triple drug therapy helps coronavirus patients recover more quickly, study finds – CNN AND Triple antiviral drug shows early promise in COVID-19 trial – Reuters AND Expert reaction to a study about a phase 2 trial of a triple antiviral drug combination treatment for COVID-19 – Science Media Centre
Preliminary Study Evaluates Interleukin-1 Blockade for Patients with Severe Covid-19
11 May, 2020 | 00:34h | UTCCommentaries: Expert reaction to study looking at use of arthritis drug anakinra in hospitalised patients with severe COVID-19 – Science Media Centre AND Small study of patients with severe COVID-19 treated with the arthritis drug anakinra finds clinical improvements – The Lancet
The Emerging Long-term Complications of Covid-19, Explained
11 May, 2020 | 00:27h | UTCThe emerging long-term complications of Covid-19, explained – Vox
Related: Coronavirus: Sickest patients face long recovery – BBC AND Surviving Covid-19 May Not Feel Like Recovery for Some – New England Journal of Medicine
Large Observational Study Finds Hydroxychloroquine Provides no Benefit in Hospitalized Patients with Covid-19
8 May, 2020 | 10:41h | UTCEditorial: The Urgency of Care during the Covid-19 Pandemic — Learning as We Go
Treatment of Community-Acquired Pneumonia During the COVID-19 Pandemic
8 May, 2020 | 10:35h | UTC
COVID-19 in Older People: A Rapid Clinical Review
8 May, 2020 | 10:22h | UTCCOVID-19 in Older People: A Rapid Clinical Review – Age and Ageing
IDSA Guidelines on the Diagnosis of COVID-19
7 May, 2020 | 09:33h | UTCInfectious Diseases Society of America Guidelines on the Diagnosis of COVID-19
Related IDSA Coronavirus Guidelines: Part 1: Treatment and Management AND Part 2: Infection Prevention
Interpreting Diagnostic Tests for SARS-CoV-2
7 May, 2020 | 09:28h | UTCInterpreting Diagnostic Tests for SARS-CoV-2 – JAMA
Autopsies Find High Incidence of Venous Thromboembolism in Patients with Covid-19
7 May, 2020 | 09:18h | UTCRelated Study: Pathological evidence of pulmonary thrombotic phenomena in severe COVID-19 – Journal of Thrombosis and Haemostasis
Observational Study: Anticoagulation Linked to Increased Survival Among Hospitalized Patients with COVID-19
7 May, 2020 | 09:16h | UTCCommentaries: Giving blood thinners to severely ill Covid-19 patients is gaining ground – STAT AND Blood thinners may improve survival among hospitalized COVID-19 patients – Mount Sinai Hospital AND Anticoagulation Associated With Improved Outcomes in Hospitalized COVID-19 Patients – American College of Cardiology AND Expert reaction to study looking at blood thinners in hospitalised patients with COVID-19 – Science Media Centre