Chest Medicine (all articles)
Triple Therapy Antiviral Combination Seems Promising for COVID-19 in Open-label, Randomized, Phase 2 Trial
11 May, 2020 | 00:42h | UTCCommentaries: Interferon beta-1b for COVID-19 – The Lancet AND New triple antiviral drug combination shows early promise for treating COVID-19 in phase 2 randomized trial – The Lancet AND A Drug Cocktail Hastens Recovery in Some Coronavirus Patients – The New York Times AND Triple drug therapy helps coronavirus patients recover more quickly, study finds – CNN AND Triple antiviral drug shows early promise in COVID-19 trial – Reuters AND Expert reaction to a study about a phase 2 trial of a triple antiviral drug combination treatment for COVID-19 – Science Media Centre
Preliminary Study Evaluates Interleukin-1 Blockade for Patients with Severe Covid-19
11 May, 2020 | 00:34h | UTCCommentaries: Expert reaction to study looking at use of arthritis drug anakinra in hospitalised patients with severe COVID-19 – Science Media Centre AND Small study of patients with severe COVID-19 treated with the arthritis drug anakinra finds clinical improvements – The Lancet
The Emerging Long-term Complications of Covid-19, Explained
11 May, 2020 | 00:27h | UTCThe emerging long-term complications of Covid-19, explained – Vox
Related: Coronavirus: Sickest patients face long recovery – BBC AND Surviving Covid-19 May Not Feel Like Recovery for Some – New England Journal of Medicine
Large Observational Study Finds Hydroxychloroquine Provides no Benefit in Hospitalized Patients with Covid-19
8 May, 2020 | 10:41h | UTCEditorial: The Urgency of Care during the Covid-19 Pandemic — Learning as We Go
Treatment of Community-Acquired Pneumonia During the COVID-19 Pandemic
8 May, 2020 | 10:35h | UTC
COVID-19 in Older People: A Rapid Clinical Review
8 May, 2020 | 10:22h | UTCCOVID-19 in Older People: A Rapid Clinical Review – Age and Ageing
IDSA Guidelines on the Diagnosis of COVID-19
7 May, 2020 | 09:33h | UTCInfectious Diseases Society of America Guidelines on the Diagnosis of COVID-19
Related IDSA Coronavirus Guidelines: Part 1: Treatment and Management AND Part 2: Infection Prevention
Interpreting Diagnostic Tests for SARS-CoV-2
7 May, 2020 | 09:28h | UTCInterpreting Diagnostic Tests for SARS-CoV-2 – JAMA
Autopsies Find High Incidence of Venous Thromboembolism in Patients with Covid-19
7 May, 2020 | 09:18h | UTCRelated Study: Pathological evidence of pulmonary thrombotic phenomena in severe COVID-19 – Journal of Thrombosis and Haemostasis
Observational Study: Anticoagulation Linked to Increased Survival Among Hospitalized Patients with COVID-19
7 May, 2020 | 09:16h | UTCCommentaries: Giving blood thinners to severely ill Covid-19 patients is gaining ground – STAT AND Blood thinners may improve survival among hospitalized COVID-19 patients – Mount Sinai Hospital AND Anticoagulation Associated With Improved Outcomes in Hospitalized COVID-19 Patients – American College of Cardiology AND Expert reaction to study looking at blood thinners in hospitalised patients with COVID-19 – Science Media Centre
Reducing Risks from Coronavirus Transmission in the Home—The Role of Viral Load
7 May, 2020 | 09:01h | UTCReducing risks from coronavirus transmission in the home—the role of viral load – The BMJ
Commentaries: Can we do more to protect people at home when a family member has coronavirus? – University of Bristol AND Coronavirus: Exposure to higher ‘viral load’ when infected could make victims more severely ill – Yahoo News
Opinion – Awake Proning for COVID-19
6 May, 2020 | 03:53h | UTCAwake Proning for COVID-19 – PulmCrit
Tests in Recovered Patients Found to be False Positives, Not Reinfections
6 May, 2020 | 03:48h | UTCTests in recovered patients found false positives, not reinfections, experts say – The Korea Herald
See also: Recovered patients who tested positive for COVID-19 likely not reinfected – Live Science AND South Korea says recovered coronavirus patients who tested positive again did not relapse: Tests picked up ‘dead virus fragments’ – Business Insider
Systematic Review: Chloroquine and Hydroxychloroquine as a Treatment for COVID‐19
6 May, 2020 | 03:44h | UTC“Pending further results from more extensive studies with more stringent study parameters, clinicians should defer from routine use of HCQ and CQ.”
Despite Anticoagulation, Patients with Severe SARS-CoV-2 Infection are at Increased Risk of Developing Thrombosis
6 May, 2020 | 03:40h | UTC
Proposal for a COVID-19 Imaging Reporting and Data System (COVID-RADS)
5 May, 2020 | 04:46h | UTC
Cohort Study: Respiratory Pathophysiology of Mechanically Ventilated Patients with COVID-19
3 May, 2020 | 22:25h | UTCCommentary: PulmCrit – Is COVID-19 ARDS, pseudoARDS, L, or H? Physiology data from Boston – PulmCrit
Related Commentary on Twitter
COVID-19 patients do not fall into distinct "phenotypes" of high and low compliance. They exhibit a continuum of compliance, mostly low, and entirely consistent with non-COVID ARDS cohorts.
https://t.co/KiHjWvIjX3 pic.twitter.com/g7FuhrlL49
— Robert Dickson (@robertpdickson) April 30, 2020
Short Review: Coagulopathy Associated with COVID-19
3 May, 2020 | 22:09h | UTCCoagulopathy associated with COVID-19 – Canadian Medical Association Journal
FDA Issues Emergency Use Authorization for the Use of Remdesivir to Treat COVID-19
3 May, 2020 | 22:03h | UTCSee also: Remdesivir: A Non-Antiviral Antiviral Drug? – Forbes
CO-RADS – A Categorical CT Assessment Scheme for Patients with Suspected COVID-19
1 May, 2020 | 03:48h | UTC
Study: Within 19 Days After Symptom Onset, 100% of Patients Test Positive for IGG
1 May, 2020 | 03:33h | UTCAntibody responses to SARS-CoV-2 in patients with COVID-19 – Nature Medicine
Commentary: Expert reaction to antibody response in COVID-19 patients – Science Media Centre
Small Observational Study Suggests Prophylactic LMWH Can Prevent COVID‐19 Disseminated Intravascular Coagulopathy
1 May, 2020 | 03:26h | UTCCOVID‐19 Coagulopathy in Caucasian patients – British Journal of Haematology
Treatment Considerations for COVID-19: A Critical Review of the Evidence
1 May, 2020 | 03:20h | UTC
Perspective: Urging Caution on Remdesivir
1 May, 2020 | 03:07h | UTCUrging Caution On Remdesivir – Forbes
Related: About Remdesivir and About “Game-Changers” – Science Translational Medicine AND Conflicting Remdesivir Trial Results Released; Experts Urge More Research – Health Policy Watch AND Is remdesivir a miracle drug to cure coronavirus? Don’t get your hopes up yet – The Conversation AND PulmCrit- First placebo-controlled RCT on remdesivir for COVID-19 – PulmCrit AND Remdesivir: the antiviral drug is being touted as a possible coronavirus treatment – but will it work? – The Guardian
“While I have enormous respect for the Institutes and their leaders, releasing the preliminary news without sharing the data behind it is highly irresponsible.”
Clinical Determinants for Fatality of 44,672 Patients with COVID-19
1 May, 2020 | 02:48h | UTCClinical determinants for fatality of 44,672 patients with COVID-19 – Critical Care