Cardiology (all articles)
Respiratory effect of beta-blockers in people with asthma and cardiovascular disease
11 Apr, 2017 | 15:48h | UTCRespiratory effect of beta-blockers in people with asthma and cardiovascular disease: population-based nested case control study – BMC Medicine (free) (RT @atscommunity)
Cardioselective beta-blockers, mostly atenolol and bisoprolol in this cohort, were not associated with increased risk of moderate or severe asthma exacerbations. In contrast, non-selective beta-blockers, mostly sotalol and carvedilol in this cohort, were associated with increased risk.
Multivitamins are probably a waste of money
12 Apr, 2017 | 15:50h | UTCVitamins and the Failure of Free-Market Health – The Atlantic (free)
“The booming dietary-supplement industry is plagued by outlandish claims, undermining credible science, and seeding confusion”.
Effect of Baseline Nutritional Status on Long-term Multivitamin Use and Cardiovascular Disease Risk – JAMA Cardiology (link to abstract – $ required for full-text)
See also: Multivitamins may not improve heart health in men – UPI (free) AND Other recent commentary on multivitamins: Multivitamins a waste of money and just create ‘very expensive urine’ – The Guardian (free)
“Multivitamin use does not prevent major CV disease events in men, regardless of baseline nutritional status” (RT @CaulfieldTim)
Hypertension Canada’s 2017 Guidelines
10 Apr, 2017 | 16:10h | UTC
Achieved blood pressure and cardiovascular outcomes in high-risk patients
11 Apr, 2017 | 15:44h | UTC
Achieved blood pressure and cardiovascular outcomes in high-risk patients: results from ONTARGET and TRANSCEND trials – The Lancet (link to abstract – $ required for full-text) (RT @AnilMakam “Lower achieved blood pressure in high risk patients for cardiovascular disease do WORSE” see Tweets)
In high-risk patients, patients who achieved a systolic blood pressure < 120 mmHg or a diastolic blood pressure < 70 mmHg had HIGHER risk of complications. “These data suggest that the lowest blood pressure possible is not necessarily the optimal target for high-risk patients”
Surgical or Transcatheter Aortic-Valve Replacement in Intermediate-Risk Patients
10 Apr, 2017 | 16:08h | UTCSurgical or Transcatheter Aortic-Valve Replacement in Intermediate-Risk Patients – New England Journal of Medicine (link to abstract – $ required for full text)
Quick Take Video Summary: SURTAVI Study: TAVR versus Open Surgery (free)
See this and other highlights from the American College of Cardiology’s 66th Annual Scientific Session (some articles are no longer free)
This innovative technology seems to be useful for patients with aortic stenosis at high risk for surgery. In this new study, it was noninferior to surgery at 2 years of follow-up in old patients (averaged nearly 80 years) at intermediate risk. Longer follow up data will be important to see if it is a suitable alternative for younger patients.
Benefits of Endovascular Treatment for Stroke Last at Least 2 Years
7 Apr, 2017 | 15:51h | UTCBenefits of Endovascular Treatment for Stroke Last at Least 2 Years – Physician’s First Watch (free)
Original article abstract ($ required for full-text): Two-Year Outcome after Endovascular Treatment for Acute Ischemic Stroke – New England Journal of Medicine
Singapore Ministry of Health Clinical Practice Guidelines: Lipids
7 Apr, 2017 | 15:24h | UTCSingapore Ministry of Health Clinical Practice Guidelines: Lipids (free PDF)
Inhaled Corticosteroids May Raise Women’s Risk of the Metabolic Syndrome
6 Apr, 2017 | 15:10h | UTCInhaled Corticosteroids May Raise Women’s Risk of the Metabolic Syndrome – NewsWise (free)
See also: Inhaled Corticosteroid Use May Up Metabolic Syndrome Risk – MPR (free)
This study was presented at #ENDO2017 and hasn’t been published yet.
Australian Clinical Guidelines for the Management of Acute Coronary Syndromes
6 Apr, 2017 | 15:08h | UTC
Can low-dose aspirin can reduce risk of death from cancer?
6 Apr, 2017 | 15:07h | UTCLow-dose aspirin can reduce risk of death from cancer, research says – CNN (free)
Not so fast: CNN claims aspirin can reduce cancer death risk, falling into observational study trap – HealthNewsReviews (free)
See also: Final Recommendation Statement: Aspirin Use to Prevent Cardiovascular Disease and Colorectal Cancer – U.S. Preventive Services Task Force (free)
Prognosis of undiagnosed chest pain
5 Apr, 2017 | 21:44h | UTCPrognosis of undiagnosed chest pain: linked electronic health record cohort study – The BMJ (free)
See also: Patients with Undiagnosed Chest Pain Still at Cardiovascular Risk – Physician’s First Watch (free)
“Chest pain rarely harmless. Even if undiagnosed 6 months after first presentation linked to increased cardiac events.” (RT @pascalmeier74)
American College of Radiology (ACR) Appropriateness Criteria Adds Topics
4 Apr, 2017 | 21:19h | UTCACR Appropriateness Criteria Adds Topics, Covers More Clinical Variants Than Ever Before (free)
Browse Appropriateness Criteria Topics (free)
Source: Newswise
This comprehensive guide from American College of Radiology (ACR) covers 230 topics with more than 1,100 clinical indications and has just been updated. It is a very useful resource for doctors in all specialties to guide which exam is most appropriate in each clinical situation.
Cardiometabolic Abnormalities Among Normal-Weight Persons From Five Racial/Ethnic Groups
5 Apr, 2017 | 14:59h | UTCCardiometabolic Abnormalities Among Normal-Weight Persons From Five Racial/Ethnic Groups in the United States: A Cross-sectional Analysis of Two Cohort Studies – Annals of Internal Medicine (link to abstract – $ required for full-text)
Sources: Certain Racial/Ethnic Groups More Likely to Have Cardiometabolic Abnormalities at Normal Weight – Physician’s First Watch (free) AND Cardiovascular Risk High Among Some Normal Weight Minorities – Medscape (free registration required)
Compared with whites, all racial/ethnic minority groups had higher prevalence of metabolic abnormalities, with a high prevalence even in persons with normal weight. The prevalence of metabolic abnormalities in whites with a BMI of 25 kg/m2 corresponded to the prevalence in BMI values of 22.9 kg/m2 in African Americans, 21.5 kg/m2 in Hispanics, 20.9 kg/m2 in Chinese Americans, and 19.6 kg/m2 in South Asians.
Insomnia associated with increased risk of heart attack and stroke
4 Apr, 2017 | 21:17h | UTCSource: Insomnia associated with increased risk of heart attack and stroke – EurekAlert (free) (RT @CaulfieldTim)
Anemia and blood transfusion in the critically ill patient with cardiovascular disease
3 Apr, 2017 | 19:14h | UTC
History of Periodontitis and Edentulism as Predictors of Cardiovascular Disease, Stroke, and Mortality
31 Mar, 2017 | 18:59h | UTCHistory of Periodontitis Diagnosis and Edentulism as Predictors of Cardiovascular Disease, Stroke, and Mortality in Postmenopausal Women – Journal of the American Heart Association (free) (RT @kamleshkhunti)
Press release: Gum disease, tooth loss may increase postmenopausal women’s risk of death – American Heart Association Rapid Access Journal Report (free)
History of periodontal disease was associated with a 12 percent higher risk of death from any cause and loss of all natural teeth was associated with a 17 percent higher risk of death from any cause.
Non–Vitamin K Antagonist Oral Anticoagulants in Patients With Atrial Fibrillation and Valvular Heart Disease
30 Mar, 2017 | 17:27h | UTCSource: SciCombinator
Except for patients with moderate/severe mitral stenosis or mechanical heart valves, who were excluded in most trials, high-dose NOACs was as effective and safe for patients with valvular heart disease as for patients without valvular disorders.
HERDOO2 rule to guide treatment duration for women with unprovoked venous thrombosis
29 Mar, 2017 | 17:07h | UTCSource: Richard Lehman’s weekly review
HERDOO2 rule stands for Hyperpigmentation, Edema, or Redness in either leg; D-dimer level ≥250 μg/L; Obesity with body mass index ≥30; or Older age, ≥65 years. The authors concluded that women with a first unprovoked VTE event and none or one of the HERDOO2 criteria have a low risk (3.0% per patient year) of recurrent VTE and can safely discontinue anticoagulants after completing short term treatment.
The year in cardiology 2016: peripheral circulation
29 Mar, 2017 | 17:00h | UTCThe year in cardiology 2016: peripheral circulation – European Heart Journal (free)
Diagnosis of chronic thromboembolic pulmonary hypertension
28 Mar, 2017 | 16:41h | UTCReview: Diagnosis of chronic thromboembolic pulmonary hypertension – European Respiratory Review (free)
Revised Framingham Stroke Risk Profile
27 Mar, 2017 | 00:48h | UTCRevised Framingham Stroke Risk Profile to Reflect Temporal Trends – Circulation (free)
“A revised Framingham Stroke Risk Profile more accurate at predicting contemporary stroke risk”.
“Instant classic paper on stroke risk prediction?! Will patients be interested in this?” (RT @MaryCushmanMD)
Alcohol and cardiovascular disease
27 Mar, 2017 | 00:46h | UTCEditorial: Alcohol and cardiovascular disease (free)
See also: Alcohol and the Heart: Moderation Still Best – Generally higher risks seen with no or heavy drinking – MedPage Today (free registration required)
Dairy consumption and risk of hypertension
23 Mar, 2017 | 16:56h | UTCContradicting evidence from previous observational studies, dairy consumption was not associated with lower blood pressure.