Cardiology (all articles)
[Abstract Only] Randomized Trial: Similar Five-Year Outcomes after PCI or CABG for Left Main Coronary Disease
30 Sep, 2019 | 00:44h | UTCFive-Year Outcomes after PCI or CABG for Left Main Coronary Disease – New England Journal of Medicine (link to abstract – $ for full-text)
Commentaries: EXCEL at 5 Years: PCI for Left Main CAD Still Noninferior to CABG – TCTMD (free) AND EXCEL: No Significant Outcome Differences in PCI vs CABG for Left Main Coronary Disease at Five Years – American College of Cardiology (free)
Related Meta-Analysis: All-cause mortality and major cardiovascular outcomes comparing percutaneous coronary angioplasty versus coronary artery bypass grafting in the treatment of unprotected left main stenosis: a meta-analysis of short-term and long-term randomised trials – OpenHeart (free) AND Percutaneous Coronary Intervention vs Coronary Artery Bypass Grafting in Patients With Left Main Coronary Artery Stenosis: A Systematic Review and Meta-analysis – JAMA Cardiology (free) AND Percutaneous Coronary Intervention Using Drug-Eluting Stents Versus Coronary Artery Bypass Grafting for Unprotected Left Main Coronary Artery Stenosis: A Meta-Analysis of Randomized Trials – Circulation: Cardiovascular Interventions (free) AND Percutaneous intervention versus coronary artery bypass graft surgery in left main coronary artery stenosis: a systematic review and meta-analysis – BMC Medicine (free) AND Mortality after coronary artery bypass grafting versus percutaneous coronary intervention with stenting for coronary artery disease: a pooled analysis of individual patient data – The Lancet (link to abstract – $ for full-text)
Related Commentary on Twitter
In an RCT, 1905 patients with left main coronary artery disease were assigned to either PCI or CABG. At five years, rates of the composite of death, stroke, or MI were not significantly different between the two groups. See the EXCEL trial. #TCT2019 https://t.co/wlpE5FPTwT
— NEJM (@NEJM) September 28, 2019
[Abstract Only] Randomized Trial: Standard Valsalva vs. Modified Valsalva for Cardioversion of SVT
30 Sep, 2019 | 00:14h | UTCStandard Valsalva vs Modified Valsalva for Cardioversion of SVT? – REBELEM (free)
Original Study: A multicenter randomized controlled trial of a modified Valsalva maneuver for cardioversion of supraventricular tachycardias – The American Journal of Emergency Medicine (link to abstract – $ for full-text)
Related Study: Postural modification to the standard Valsalva manoeuvre for emergency treatment of supraventricular tachycardias (REVERT): a randomised controlled trial – The Lancet (free), Commentaries: Supraventricular tachycardia: back to basics – The Lancet (free) AND The REVERT Trial: A Modified Valsalva Maneuver to Convert SVT – REBELEM (free)
Systematic Review: Beta-blockers to Prevent Death or Serious Events After Non-Cardiac Surgery
27 Sep, 2019 | 08:30h | UTCPerioperative beta‐blockers for preventing surgery‐related mortality and morbidity in adults undergoing non‐cardiac surgery – Cochrane Library (free)
Summary: Beta-blockers to prevent death or serious events after surgery not involving the heart – Cochrane Library (free)
[Abstract Only] Randomized Trial: Dual Antiplatelet Therapy vs. Monotherapy with a P2Y12 Inhibitor in High-Risk Patients after PCI
27 Sep, 2019 | 08:25h | UTCTicagrelor with or without Aspirin in High-Risk Patients after PCI – New England Journal of Medicine (link to abstract – $ for full-text)
Commentaries: Ticagrelor With Aspirin or Alone in High-Risk Patients After Coronary Intervention – TWILIGHT – American College of Cardiology (free) AND TWILIGHT: Ticagrelor Monotherapy Lowers Bleeding Without Increasing Ischemic Events – TCTMD (free)
Meta-analysis: Therapies for Preventing Cardiotoxicity in Patients Undergoing Chemotherapy
26 Sep, 2019 | 08:35h | UTC
Related Commentary on Twitter
Efficacy of Neurohormonal Therapies to Prevent Cardiotoxicity in Pts w/ Cancer
Featured in Inaugural Issue @JACCJournals
#JACCCardioOnc w/@Hirji1987 @ambarish4786Meta-analysis (n=17): ~4% attenuation of LVEF decline, unmet need for large powered RCTshttps://t.co/TCC4NnxQli pic.twitter.com/G1yLF4b83T
— Muthu Vaduganathan (@mvaduganathan) September 24, 2019
Guideline Synopsis: Prevention and Management of Venous Thromboembolism
25 Sep, 2019 | 08:33h | UTCPrevention and Management of Venous Thromboembolism – JAMA (free for a limited period)
Clinical Review Audio: An Update on the Diagnosis and Treatment of Venous Thromboembolic Disease (free)
Original American Society of Hematology 2018 Guidelines: Prophylaxis for hospitalized and nonhospitalized medical patients (free) AND Diagnosis of venous thromboembolism (free) AND Optimal management of anticoagulation therapy (free) AND Treatment of pediatric venous thromboembolism (free) AND Venous thromboembolism in the context of pregnancy (free) AND Heparin-induced thrombocytopenia (free)
Cohort Study: Preeclampsia and Cardiovascular Disease
25 Sep, 2019 | 08:09h | UTCPreeclampsia and Cardiovascular Disease in a Large UK Pregnancy Cohort of Linked Electronic Health Records: A CALIBER Study – Circulation (free for a limited period)
Commentary: Hypertension during pregnancy can increase later risk of heart disease – King’s College London (free)
Related: Cohort Study: Cardiovascular Disease After Hypertensive Disorders of Pregnancy Largely Explained by Conventional Cardiovascular Risk Factors (recent studies on the subject)
Consensus Recommendations for Ambulatory Blood Pressure Monitoring
24 Sep, 2019 | 08:26h | UTCRelated Reviews: Role of Ambulatory and Home Blood Pressure Monitoring in Clinical Practice: A Narrative Review – Annals of Internal Medicine (free) AND Ambulatory Blood Pressure Monitoring in Clinical Practice: A Review – American Journal of Medicine (free)
KDIGO Controversies Conference: Chronic Kidney Disease and Valvular Heart Disease
24 Sep, 2019 | 08:25h | UTC
Systematic Review: Perioperative Beta‐blockers in Adults Undergoing Cardiac Surgery
24 Sep, 2019 | 08:12h | UTCPerioperative beta‐blockers for preventing surgery‐related mortality and morbidity in adults undergoing cardiac surgery – Cochrane Library (free)
Summary: Beta-blockers to prevent death or serious events after heart surgery – Cochrane Library (free)
Related: Perioperative beta‐blockers for preventing surgery‐related mortality and morbidity – Cochrane Library (free)
Podcast: Dominate Perioperative Medication Management
24 Sep, 2019 | 08:14h | UTC#174 Dominate Perioperative Medication Management – The Curbsiders Internal Medicine Podcast (free)
Related Episode: #135 Perioperative Medicine: Assess & Optimize Risk (free)
See also: Episode List
Position Paper: Physical Activity for Patients with heart failure
24 Sep, 2019 | 07:53h | UTC
Prevention of Cardiac Surgery-Associated Acute Kidney Injury: A Review of Current Strategies
24 Sep, 2019 | 07:52h | UTC
[Abstract Only] Randomized Trial: SGLT2 Inhibitor Improves Outcomes in Patients with Heart Failure Even in the Absence of Diabetes
20 Sep, 2019 | 08:27h | UTCDapagliflozin in Patients with Heart Failure and Reduced Ejection Fraction – New England Journal of Medicine (link to abstract – $ for full-text)
Related 2019 ESC Congress News Release, Before Publication: Randomized Trial: SGLT2 inhibitors Seems Beneficial for Heart Failure Even in Nondiabetics (free commentaries)
Commentaries: SGLT2 Inhibitor Dapagliflozin Lowers Risk for Worsening Heart Failure – NEJM Journal Watch (free) AND New research shows dapagliflozin used to treat diabetes can also treat heart failure, in patients with and without diabetes (the DAPA-HF Study) – Diabetologia (free)
Cohort Study: Metformin Linked to Reduced Risk of Cardiovascular Events Compared to Sulfonylurea Among Patients with Diabetes and Reduced Kidney Function
20 Sep, 2019 | 08:19h | UTCAssociation of Treatment With Metformin vs Sulfonylurea With Major Adverse Cardiovascular Events Among Patients With Diabetes and Reduced Kidney Function – JAMA (free for a limited period)
Commentaries: Metformin Superior for Lowering CV Risk in Diabetics Who Progress to CKD – Renal & Urology News (free) AND Metformin Monotherapy Benefits Heart Even in Early CKD – MedPage Today (free registration required)
Related Commentary on Twitter
Monotherapy treatment with #metformin, compared with a #sulfonylurea, was associated with a lower risk of MACE among patients with diabetes and reduced kidney function https://t.co/Z1EZAjOOET
— JAMA (@JAMA_current) September 19, 2019
Meta-Analysis: Transcatheter vs. Surgical Aortic Valve Replacement in Low-Risk Patients
20 Sep, 2019 | 08:07h | UTCTranscatheter Versus Surgical Aortic Valve Replacement in Low-Risk Patients – Journal of the American College of Cardiology (link to abstract – $ for full-text)
Commentaries: Meta-Analysis of TAVR vs. SAVR in Low-Risk Patients – American College of Cardiology (free) AND TAVR Survival Surpasses SAVR in Low-Risk Patients: Meta-analysis – Medscape (free registration required)
“The one clear unknown that everyone points to is valve durability” (form Medscape)
“longer follow-up regarding valve degeneration will be needed to confirm TAVR as the preferred treatment for low-risk patients with severe AS.” (from American College of Cardiology)
[Abstract Only] Randomized Trial: Polypill for Cardiovascular Disease Prevention in an Underserved Population
19 Sep, 2019 | 08:19h | UTCPolypill for Cardiovascular Disease Prevention in an Underserved Population – New England Journal of Medicine (link to abstract – $ for full-text)
Commentaries: Polypill Drops BP, LDL Cholesterol in a Disadvantaged US Population – TCTMD (free) AND One daily combo pill helps lower heart disease risk in study of underserved patients – American Heart Association (free) AND Fixed Dose Combination Polypill Can Reduce Barriers to Cardiovascular Care – MedicalResearch.com (free) AND One pill with four drugs may lower heart risks in poor population – Reuters (free) AND All-in-One Pill Reduces Blood Pressure, Cholesterol Levels in U.S. Study – Vanderbilt University Medical Center (free)
Related Randomized Trial: Effectiveness of Polypill for Primary and Secondary Prevention of Cardiovascular Diseases (link to abstract and commentaries)
See also: Clinical Impact of the Polypill for Cardiovascular Prevention in Latin America: A Consensus Statement of the Inter-American Society of Cardiology – Global Heart (free) AND Perspective: The Polypill and the Long Journey to Major Impact (opinion and reviews on the subject) AND Research: Low-Dose ‘Triple Pill’ Lowers Blood Pressure More Than Usual Care (free commentaries)
[Abstract Only] Study: Benefits and Harms of Aspirin for Primary Prevention of Cardiovascular Disease
18 Sep, 2019 | 08:36h | UTCPersonalized Prediction of Cardiovascular Benefits and Bleeding Harms From Aspirin for Primary Prevention: A Benefit–Harm Analysis – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentaries: Aspirin may benefit some people without cardiovascular disease, new analysis finds – ACP Internist (free) AND Some Adults Without Heart Disease May Benefit From Aspirin – MedicalResearch.com (free) AND Expert reaction to study looking at benefits and harms of aspirin in people without cardiovascular disease – Science Media Centre (free)
[Abstract Only] Cohort Study: Complete vs. Staged Repair of Tetralogy of Fallot in Neonates
18 Sep, 2019 | 01:06h | UTCComplete vs. Staged Repair of Tetralogy of Fallot in Neonates – American College of Cardiology (free)
Original Study: 2-Year Outcomes After Complete or Staged Procedure for Tetralogy of Fallot in Neonates – Journal of the American College of Cardiology (link to abstract – $ for full-text)
Scientific Statement: Review of Current Evidence and Clinical Recommendations on the Effects of Low-carbohydrate and Very-low-carbohydrate (Including Ketogenic) Diets for the Management of Body Weight and Other Cardiometabolic Risk Factors
17 Sep, 2019 | 07:25h | UTC
Cohort Study: Lower Carbohydrate Diets and All-cause and Cause-specific Mortality
17 Sep, 2019 | 07:19h | UTCCommentary: Lower Carbohydrate Diets, All-Cause and Cause-Specific Mortality – American College of Cardiology (free)
EHRA/EAPCI Expert Consensus Statement on Catheter-based Left Atrial Appendage Occlusion
17 Sep, 2019 | 01:08h | UTC
ACC Consensus Decision Pathway for Heart Failure Hospitalizations
16 Sep, 2019 | 02:24h | UTCKey Points to Remember: ACC Consensus Decision Pathway for Heart Failure Hospitalizations – American College of Cardiology (free)
[Abstract Only] Study: High Prevalence of Obstructive Sleep Apnea in Patients with Resistant Hypertension
16 Sep, 2019 | 02:18h | UTCPrevalence, Characteristics and Association of Obstructive Sleep Apnea with Blood Pressure Control in Patients with Resistant Hypertension – Annals of the American Thoracic Society (link to abstract – $ for full-text)
Commentaries: Most patients with resistant hypertension have sleep apnoea – OnMedica (free) AND More Severe OSA Leads to Higher Blood Pressure in Patients with Resistant Hypertension – American Thoracic Society (free) AND Obstructive Sleep Apnea Common in Patients with Resistant Hypertension – MedicalResearch.com (free)
ACE inhibitors and ARBs: Managing Potassium and Renal Function
16 Sep, 2019 | 02:14h | UTCEditorial: ACE inhibitor and ARB therapy: Practical recommendations (free)