Cardiology (all articles)
Study: Evaluation of a Common Prescribing Cascade of Calcium Channel Blockers and Diuretics in Older Adults with Hypertension
25 Feb, 2020 | 06:42h | UTCEvaluation of a Common Prescribing Cascade of Calcium Channel Blockers and Diuretics in Older Adults With Hypertension – JAMA Internal Medicine (free for a limited period)
Commentary: Antihypertensive Prescribing Cascades as High-Priority Targets for Deprescribing – JAMA Internal Medicine (free for a limited period)
Related Commentary on Twitter
Prescribing cascades occur when a second medicine is prescribed to counteract the effects of the first medicine. This @JAMAInternalMed article is the strongest empiric evidence I have seen that these cascades are very real #geriatrics https://t.co/KmJ2nhLlXM
— Ken Covinsky (@geri_doc) February 24, 2020
JAMA Patient Page: Aspirin for Prevention of Cardiovascular Disease
25 Feb, 2020 | 06:07h | UTCAspirin for Prevention of Cardiovascular Disease – JAMA (free)
Related: Aspirin for primary prevention of cardiovascular disease: a meta-analysis with a particular focus on subgroups – BMC Medicine (free) AND Acetylsalicylic acid for primary prevention of cardiovascular events – Canadian Family Physician (free) AND Evidence evolving on aspirin as prevention – ACP Internist (free) AND Benefits and Harms of Aspirin for Primary Prevention of Cardiovascular Disease – Annals of Internal Medicine (link to abstract and commentaries) AND Aspirin for Primary Prevention: Is This the End of the Road? (selection of resources on the subject)
Cohort Study: The Associations of Major Foods and Fiber with Risks of Ischemic and Hemorrhagic Stroke
25 Feb, 2020 | 06:34h | UTCThe associations of major foods and fibre with risks of ischaemic and haemorrhagic stroke: a prospective study of 418 329 participants in the EPIC cohort across nine European countries – European Heart Journal (free for a limited period)
Commentaries: Study of 418,000 Europeans finds different foods linked to different types of stroke – European Society of Cardiology (free) AND Expert reaction to study looking at foods and stroke risk – Science Media Centre (free)
Related Commentary on Twitter
Associations in #diet and stroke in >418,000 Europeans from 9 countries w/ ~13 year follow up https://t.co/8WqqzoPO22 @escardio @tammy_tong @Oxford_NDPH @MRC_Epid et al
(usual caveats) but note risk w/ eggs, red meat; poss benefit of dairy products, fiber, fruit & vegetables pic.twitter.com/3ubKmkxzvX— Eric Topol (@EricTopol) February 24, 2020
[Abstract Only] Meta-Analysis: Lower vs. Standard INR Targets in Atrial Fibrillation
25 Feb, 2020 | 06:04h | UTCLower versus Standard INR Targets in Atrial Fibrillation: A Systematic Review and Meta-Analysis of Randomized Controlled Trials – Thrombosis and Haemostasis (link to abstract – $ for full-text)
Source: EvidenceAlerts
AHA Scientific Statement: Sudden Cardiac Arrest Survivorship
23 Feb, 2020 | 22:19h | UTC
Meta-Analysis: Comparison of Cardiovascular Events Among Users of Different Classes of Antihypertension Medications
23 Feb, 2020 | 22:10h | UTC
Position Statement: Antithrombotic Therapy in Patients with Acute Coronary Syndrome Complicated by Cardiogenic Shock or Out-of-hospital Cardiac Arrest
23 Feb, 2020 | 21:47h | UTC
Practical Considerations for the Use of Sodium-Glucose Co-Transporter 2 Inhibitors in Heart Failure
23 Feb, 2020 | 21:46h | UTC
Cohort Study: Aromatase Inhibitors and the Risk of Cardiovascular Outcomes in Women with Breast Cancer
21 Feb, 2020 | 10:35h | UTCAromatase Inhibitors and the Risk of Cardiovascular Outcomes in Women With Breast Cancer: A Population-Based Cohort Study – Circulation (free for a limited period)
[Abstract Only] Observational Study: Effects of Pre-Hospital Administration of Epinephrine in Pediatric Patients with Out-of-Hospital Cardiac Arrest
20 Feb, 2020 | 08:21h | UTCPre-Hospital Administration of Epinephrine in Pediatric Patients With Out-of-Hospital Cardiac Arrest – Journal of the American College of Cardiology (link to abstract – $ for full-text)
Commentaries: Epinephrine for Pediatric OHCA Mirrors PARAMEDIC2 – JournalFeed (free) AND Getting to the heart of epinephrine use in pediatric cardiac arrest patients – Osaka University (free)
Related Study: Randomized Trial: Epinephrine in Out-of-Hospital Cardiac Arrest (free study and commentaries)
Meta-Analysis: Effects of Percutaneous Coronary Intervention on Death and Myocardial Infarction Stratified by Stable and Unstable Coronary Artery Disease
19 Feb, 2020 | 10:21h | UTCEditorial: The ISCHEMIA Trial Meets the Rashomon Effect: Lessons for Clinical Practice (free for a limited period)
Related Commentary on Twitter
🔺meta-analysis on effects of percutaneous coronary intervention in stable & unstable CAD;includes ISCHEMIA trial
🔺PCI prevents death, cardiac death,&MI in pts w unstable CAD
🔺For pts w stable CAD,PCI shows🚫evidence of an effect on any of these outcomes https://t.co/zsEWWuVPmL pic.twitter.com/y0WLwIIVef— Circ: CQO (@CircOutcomes) February 18, 2020
Studies: Little Benefit from Polygenic Risk Score vs. Clinical Risk Score for Predicting Cardiovascular Risk
19 Feb, 2020 | 10:19h | UTCPredictive Accuracy of a Polygenic Risk Score Compared with a Clinical Risk Score for Incident Coronary Heart Disease – JAMA (free for a limited period)
Related Study: Predictive Accuracy of a Polygenic Risk Score–Enhanced Prediction Model vs a Clinical Risk Score for Coronary Artery Disease – JAMA (free for a limited period)
Editorial: Do Polygenic Risk Scores Improve Patient Selection for Prevention of Coronary Artery Disease? (free)
Commentary: Gene tests for heart disease risk have limited benefit – Imperial College London (free)
Investigation: “Heart doctors ‘held back stent death data’”
19 Feb, 2020 | 08:27h | UTCHeart doctors ‘held back stent death data’ – BBC (free)
Related: BBC Investigation on the Reporting of the EXCEL Trial Raises Concerns Over the Safety of Stents for Left Main Disease in Patients at Low Risk for Surgery (free investigation, video, and commentaries) AND EACTS Calls for Independent Left Main CAD Evidence Review, Urges ESC Input – TCTMD (free) AND Changing Evidence, Changing Practice – European Association of Cardio-Thoracic Surgery (free)
Cluster Randomized Trial: Effect of Salt Substitution on Community-wide Blood Pressure and Hypertension Incidence
18 Feb, 2020 | 08:24h | UTCEffect of salt substitution on community-wide blood pressure and hypertension incidence – Nature Medicine (free for a limited period)
Commentaries Before Publication at #ESCCongress: Community-based salt substitution programme lowers blood pressure – European Society of Cardiology (free) AND Community-Level Salt-Swapping Strategy Pays Dividends in Peru – TCTMD (free)
Related Commentary on Twitter
What happens when you replace salt with 25% KCl (+75% NaCl) in many villages in Peru?https://t.co/hL053MXjHq
A small reduction in blood pressure and 51% reduced risk of developing hypertension@NatureMedicine by @jjaimemiranda @cronicasperu
@CayetanoHeredia and colleagues pic.twitter.com/gqBtbJN47k— Eric Topol (@EricTopol) February 17, 2020
Large Observational Study Suggests Hydrochlorothiazide may be as Effective as Chlortalidone with Less Adverse Effects
18 Feb, 2020 | 08:17h | UTCComparison of Cardiovascular and Safety Outcomes of Chlorthalidone vs Hydrochlorothiazide to Treat Hypertension – JAMA Internal Medicine (free for a limited period)
Commentary: Hypertension Treatments with Chlorthalidone vs HCTZ: Cardiac and Safety Outcomes – MedicalResearch.com (free)
2020 Focused Update of the 2017 ACC Expert Consensus Decision Pathway on the Management of Mitral Regurgitation
16 Feb, 2020 | 21:41h | UTCSee also: Mitral Regurgitation Management Focused Update: Key Points – American College of Cardiology (free)
Extracorporeal Membrane Oxygenation for Refractory Cardiac Arrest: A Retrospective Multicenter Study
16 Feb, 2020 | 21:02h | UTC
Low-density Lipoproteins Cause Atherosclerotic Cardiovascular Disease: Pathophysiological, Genetic, and Therapeutic Insights
16 Feb, 2020 | 20:57h | UTCLow-density lipoproteins cause atherosclerotic cardiovascular disease: pathophysiological, genetic, and therapeutic insights: a consensus statement from the European Atherosclerosis Society Consensus Panel – European Heart Journal (free for a limited period)
Comparing American and European Guidelines for the Initial Diagnosis of Stable Ischemic Heart Disease: A Paradigm Shift from Exercise ECG Testing to Imaging-based Modalities
16 Feb, 2020 | 20:58h | UTC
Angina: Contemporary Diagnosis and Management
16 Feb, 2020 | 20:47h | UTCAngina: contemporary diagnosis and management – Heart (free)
Basic Point‐of‐care Ultrasound Framework Based on the Airway, Breathing, and Circulation Approach for the Initial Management of Shock and Dyspnea
16 Feb, 2020 | 20:46h | UTCSource: Grupo UTIclínica – HCFMUSP
Observational Study: Higher Risk of Death and Major Bleeding with Intravascular Microaxial Left Ventricular Assist Device vs. Intra-aortic Balloon Pump Among Patients with Acute MI Complicated by Cardiogenic Shock
12 Feb, 2020 | 07:27h | UTCAssociation of Use of an Intravascular Microaxial Left Ventricular Assist Device vs Intra-aortic Balloon Pump With In-Hospital Mortality and Major Bleeding Among Patients With Acute Myocardial Infarction Complicated by Cardiogenic Shock – JAMA (free for a limited period)
Editorial: Microaxial Left Ventricular Assist Devices: In Search of an Appropriate Indication (free for a limited period)
Commentary: High-tech pump may increase risk of death and bleeding, study finds – Yale News (free)
Related Commentary on Twitter (Thread – Click for More)
Major paper published by @JAMA_current today that uses real-world data to examine outcomes among patients undergoing PCI for AMI who received mechanical circulatory support, comparing the Impella to IABP (and to medical therapy) (1/9) https://t.co/EsoRfSj1eH
— Joseph Ross (@jsross119) February 10, 2020
Review: Cardiovascular Safety Considerations in the Treatment of Neurogenic Orthostatic Hypotension
11 Feb, 2020 | 02:01h | UTC
Study: Lower GI-bleeding in Anticoagulated Patients with Atrial Fibrillation Should Always Raise Suspicion of Colorectal Cancer
9 Feb, 2020 | 20:47h | UTCCommentary: GI Bleeding and Colorectal Cancer Risk in Anticoagulated AF Patients – American College of Cardiology (free) AND GI bleeding often mistaken as side effect of blood thinners when it could indicate cancer – Cardiovascular Business (free)
Opinion: “Abolish the Tilt Table Test for the Workup of Syncope!”
9 Feb, 2020 | 20:41h | UTCAbolish the Tilt Table Test for the Workup of Syncope! – Circulation (free for a limited period)


