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Coronary Heart Disease

RCT | A double-dose influenza vaccination during hospitalization for acute coronary syndrome did not improve outcomes compared to standard-dose outpatient vaccination.

13 Sep, 2022 | 13:19h | UTC

Influenza vaccination strategy in acute coronary syndromes: the VIP-ACS trial – European Heart Journal

 

Commentary on Twitter

 

RCT | Effects of Nicorandil administration on infarct size in patients with ST‐Segment–Elevation Myocardial Infarction undergoing primary percutaneous coronary intervention.

11 Sep, 2022 | 22:37h | UTC

Effects of Nicorandil Administration on Infarct Size in Patients With ST‐Segment–Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention: The CHANGE Trial – Journal of the American Heart Association

 

Study suggests many stable patients with ST-Elevation Myocardial Infarction may not require routine admission to a cardiac intensive care unit following PCI reperfusion.

8 Sep, 2022 | 14:45h | UTC

Incidence and Predictors of Adverse Events Among Initially Stable ST‐Elevation Myocardial Infarction Patients Following Primary Percutaneous Coronary Intervention – Journal of the American Heart Association

 

#ESCCongress | Study shows long-term Evolocumab appears to be safe in patients with established atherosclerotic cardiovascular disease.

30 Aug, 2022 | 12:12h | UTC

Long-Term Evolocumab in Patients with Established Atherosclerotic Cardiovascular Disease – Circulation

News Release: Long-term evolocumab therapy leads to further reductions in cardiovascular events – European Society of Cardiology

Original Article: Evolocumab and Clinical Outcomes in Patients with Cardiovascular Disease – New England Journal of Medicine

 

Commentary on Twitter

 

#ESCCongress – RCT | In patients with severe ischemic left ventricular systolic dysfunction under optimal medical therapy, revascularization by PCI did not improve outcomes.

29 Aug, 2022 | 12:38h | UTC

Percutaneous Revascularization for Ischemic Left Ventricular Dysfunction – New England Journal of Medicine (link to abstract – $ for full-text)

News Release: Coronary stenting does not benefit patients with severe left ventricular dysfunction – European Society of Cardiology

Commentary: DANCAVAS: CV Screening Did Not Significantly Reduce Incidence of Death in Older Males – American College of Cardiology

 

Commentary on Twitter

 

#ESCCongress – RCT | Routine functional testing is not better than standard care in high-risk patients after percutaneous coronary intervention.

29 Aug, 2022 | 12:32h | UTC

Routine Functional Testing or Standard Care in High-Risk Patients after PCI – New England Journal of Medicine (link to abstract – $ for full-text)

 

Commentary on Twitter

 

#ESCCongress | In patients within 6 months of a myocardial infarction, a polypill containing aspirin, ramipril, and atorvastatin resulted in a lower risk of major adverse cardiovascular events compared to usual care.

29 Aug, 2022 | 12:27h | UTC

Polypill Strategy in Secondary Cardiovascular Prevention – New England Journal of Medicine (link to abstract – $ for full-text)

News Release: Polypill reduces cardiovascular events in heart attack patients compared to usual care – European Society of Cardiology

Commentaries:

SECURE: Treatment With Polypill Significantly Lowers Risk of Major CV Events – American College of Cardiology

Polypill Strategy Lowers Adverse CV Event Risk in Secondary Prevention – HCPLive

Related: M-A: Polypills with and without aspirin substantially reduce cardiovascular disease, myocardial infarction, stroke, revascularization, and cardiovascular death in primary cardiovascular disease prevention. (several studies on the subject)

 

[News release – not published yet] #ESCCongress – RCT | Allopurinol does not improve cardiovascular outcomes in ischemic heart disease patients.

29 Aug, 2022 | 12:15h | UTC

Allopurinol does not improve cardiovascular outcomes in ischaemic heart disease patients – European Society of Cardiology

Commentary:

ALL-HEART: Gout Drug Allopurinol No Help in CV Prevention – TCTMD

No improvement with allopurinol for patients with ischemic heart disease: ALL-HEART – Cardiology Now

 

Vasospastic angina: a contemporary review of its pathophysiology, diagnosis and management.

25 Aug, 2022 | 11:53h | UTC

Vasospastic Angina: A Contemporary Review of its Pathophysiology, Diagnosis and Management – Heart International

 

Commentary on Twitter

 

M-A | Association of dual antiplatelet therapy with ticagrelor with vein graft failure after coronary artery bypass graft surgery.

10 Aug, 2022 | 15:32h | UTC

Association of Dual Antiplatelet Therapy With Ticagrelor With Vein Graft Failure After Coronary Artery Bypass Graft Surgery: A Systematic Review and Meta-analysis – JAMA (free for a limited period)

Editorial: Balancing the Risks and Benefits of Antiplatelet Therapy After Coronary Artery Bypass Graft Surgery – JAMA (free for a limited period)

Author Interview: Coronary Artery Bypass Surgery in 2022 – JAMA

News Release: Two-medication strategy offers both benefit and risk after coronary artery bypass surgery – Weill Cornell Medicine

 

Systematic Review | Smoking cessation for secondary prevention of cardiovascular disease.

9 Aug, 2022 | 12:42h | UTC

Smoking cessation for secondary prevention of cardiovascular disease – Cochrane Library

Summary: Does stopping smoking make people with heart disease less likely to have another heart attack? – Cochrane Library

 

Is the contemporary care of older persons with acute coronary syndrome evidence-based?

8 Aug, 2022 | 11:48h | UTC

Is the contemporary care of the older persons with acute coronary syndrome evidence-based? – European Heart Journal Open

 

Commentary from the author on Twitter

 

RCT | External support for saphenous vein grafts in coronary artery bypass surgery.

26 Jul, 2022 | 11:44h | UTC

External Support for Saphenous Vein Grafts in Coronary Artery Bypass Surgery: A Randomized Clinical Trial – JAMA Cardiology (link to abstract – $ for full-text)

Commentary: In CABG patients, external graft support devices fail to prolong patency of saphenous vein graft: JAMA – Medical Dialogues

 

Commentary on Twitter

 

Open-label RCT | Moderate-intensity statin plus ezetimibe is noninferior to high-intensity statin monotherapy in patients with atherosclerotic cardiovascular disease.

20 Jul, 2022 | 12:32h | UTC

Long-term efficacy and safety of moderate-intensity statin with ezetimibe combination therapy versus high-intensity statin monotherapy in patients with atherosclerotic cardiovascular disease (RACING): a randomised, open-label, non-inferiority trial – The Lancet (link to abstract – $ for full-text)

 

Position Paper | Post-discharge and long-term follow-up after an acute coronary syndrome.

18 Jul, 2022 | 11:22h | UTC

Post-discharge and long-term follow-up after an acute coronary syndrome: International Collaborative Group of CNCF position paper – Archives of Medical Science

 

Commentary on Twitter

 

Coronary Artery Disease Reporting and Data System (CAD-RADS 2.0) reporting system for patients undergoing coronary CT angiography.

14 Jul, 2022 | 12:49h | UTC

CAD-RADSTM 2.0 2022 Coronary Artery Disease – Reporting and Data System An Expert Consensus Document of the Society of Cardiovascular Computed Tomography (SCCT), the American College of Cardiology (ACC), the American College of Radiology (ACR) and the North America Society of Cardiovascular Imaging (NASCI) – Journal of Cardiovascular Computed Tomography

Commentary: SCCT Releases New Expert Consensus Document on CAD Reporting – American College of Cardiology

 

Secondary analysis of a RCT | Duration of antiplatelet therapy after complex percutaneous coronary intervention in patients at high bleeding risk.

11 Jul, 2022 | 12:06h | UTC

Duration of antiplatelet therapy after complex percutaneous coronary intervention in patients at high bleeding risk: a MASTER DAPT trial sub-analysis – European Heart Journal

Commentaries:

EuroPCR 2022: Short DAPT shows benefit for high-bleeding risk patients regardless of PCI complexity – CardiovascularNews

One-Month DAPT Enough for Complex PCI if Bleeding Risk High – Medscape (free registration required)

 

Commentary on Twitter

 

RCT | Distal radial vs. conventional radial access for coronary angiography and intervention.

5 Jul, 2022 | 11:54h | UTC

Distal Versus Conventional Radial Access for Coronary Angiography and Intervention: The DISCO RADIAL Trial – JACC Cardiovascular Interventions

Editorial: Less Is More, But Not Always: Distal Transradial Access for Radial Artery Occlusion Prevention

Commentaries:

DISCO RADIAL: Distal Radial and Transradial Access Similar When Performed With Rigorous Hemostasis – American College of Cardiology

Distal radial access not better than conventional approach in preventing radial arterial occlusion, DISCO RADIAL Trial – Medical Dialogues

Distal Radial Access Doesn’t Lower Risk of Occlusion: DISCO RADIAL – TCTMD

Fancy Coronary Access Technique Disappoints in Preventing Radial Artery Occlusions — Distal radial approach did result in easier hemostasis, however – MedPage Today (free registration required)

 

Commentary on Twitter

Guideline Synopsis | Evaluation and diagnosis of chest pain.

4 Jul, 2022 | 12:49h | UTC

Evaluation and Diagnosis of Chest Pain – JAMA (free for a limited period)

Original Guideline:

2021 AHA/ACC/ASE/CHEST/SAEM/SCCT/SCMR Guideline for the Evaluation and Diagnosis of Chest Pain: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines – Journal of the American College of Cardiology

News Release: First-Ever Guideline Focused Solely on Chest Pain Evaluation, Diagnosis Released

Guideline Hub: Guideline for the Evaluation and Diagnosis of Chest Pain

Key Points: 2021 AHA/ACC Chest Pain Guideline – American College of Cardiology

Commentary: New Chest Pain Guidelines Out at Last: Most Tests Have a Role – TCTMD

Cohort Study: B‐Type Natriuretic Peptide and long‐term cardiovascular mortality in patients with coronary heart disease.

1 Jul, 2022 | 11:04h | UTC

B‐Type Natriuretic Peptide and Long‐Term Cardiovascular Mortality in Patients With Coronary Heart Disease – Journal of the American Heart Association

 

RCT: Prothrombin complex concentrate vs. plasma for post–cardiopulmonary bypass coagulopathy and bleeding.

30 Jun, 2022 | 10:50h | UTC

Prothrombin Complex Concentrate vs Plasma for Post–Cardiopulmonary Bypass Coagulopathy and Bleeding: A Randomized Clinical Trial – JAMA Surgery (free for a limited period)

 

Commentary on Twitter

https://twitter.com/JAMASurgery/status/1542176079728738305

 

RCT: Effectiveness and safety of early initiation of poststernotomy cardiac rehabilitation exercise training.

23 Jun, 2022 | 12:59h | UTC

Effectiveness and Safety of Early Initiation of Poststernotomy Cardiac Rehabilitation Exercise Training: The SCAR Randomized Clinical Trial – JAMA Cardiology (free for a limited period)

 

Commentary on Twitter

 

M-A: Early versus delayed complete revascularization in patients presenting with ST-segment elevation myocardial infarction and multivessel disease.

23 Jun, 2022 | 10:11h | UTC

Early versus delayed complete revascularisation in patients presenting with ST-segment elevation myocardial infarction and multivessel disease: a systematic review and meta-analysis of randomised controlled trials – openheart

 

Cohort Study: Association between short-term, chronic localized and chronic widespread pain and risk for cardiovascular disease.

22 Jun, 2022 | 11:18h | UTC

The association between short-term, chronic localized and chronic widespread pain and risk for cardiovascular disease in the UK Biobank – European Journal of Preventive Cardiology

 

Safety of bariatric surgery in patients with previous acute coronary events or heart failure: nationwide cohort study.

21 Jun, 2022 | 10:44h | UTC

Safety of bariatric surgery in patients with previous acute coronary events or heart failure: nationwide cohort study – BJS Open

 

Commentary on Twitter

 

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