Allergy & Immunology
[Abstract Only] Randomized Trial: Ruxolitinib Cream for Treatment of Vitiligo
12 Jul, 2020 | 23:58h | UTCRuxolitinib cream for treatment of vitiligo: a randomised, controlled, phase 2 trial – The Lancet
Related Commentary on Twitter
NEW—Treatment with ruxolitinib cream was associated with substantial repigmentation of vitiligo lesions up to 52 weeks of treatment, and all doses were well tolerated: finding from a randomised, controlled, phase 2 trial https://t.co/Td5nlsMcYI pic.twitter.com/CHvtspGstQ
— The Lancet (@TheLancet) July 10, 2020
Developing a SARS-CoV-2 Vaccine at Warp Speed
7 Jul, 2020 | 08:59h | UTCDeveloping a SARS-CoV-2 Vaccine at Warp Speed – JAMA
Related Video: Coronavirus Vaccine Development – JAMA
Study Addresses Clinical Validity and Utility of Serum Antibodies to SARS-CoV-2
7 Jul, 2020 | 08:55h | UTC
Podcast: A Clinical Pharmacologist’s Perspective on Penicillin Allergy
7 Jul, 2020 | 08:43h | UTCA Clinical Pharmacologist’s Perspective on Penicillin Allergy – JAMA
Editorial: Is a “Cytokine Storm” Relevant to COVID-19?
1 Jul, 2020 | 07:59h | UTCIs a “Cytokine Storm” Relevant to COVID-19? – JAMA Internal Medicine
Related Commentary on Twitter
NEW @JAMAInternalMed
Is a “Cytokine Storm” Relevant to #COVID19 ?
"Although the term cytokine storm conjures up dramatic imagery and has captured the attention of the mainstream and scientific media, the current data do not support its use"https://t.co/0NuCUHdBdq— Antibiotic Steward Bassam Ghanem 🅱️C🆔🅿️🌟 (@ABsteward) June 30, 2020
[Preprint] Immunity to COVID-19 is Probably Higher than Tests Have Shown
30 Jun, 2020 | 08:04h | UTCImmunity to COVID-19 is probably higher than tests have shown – Karolinska Institutet
Original Study: Robust T cell immunity in convalescent individuals with asymptomatic or mild COVID-19 – bioRxiv
Studies: Childhood Multisystem Inflammatory Syndrome — A New Challenge in the Pandemic
30 Jun, 2020 | 07:57h | UTCStudy 1: Multisystem Inflammatory Syndrome in U.S. Children and Adolescents – New England Journal of Medicine
Study 2: Multisystem Inflammatory Syndrome in Children in New York State – New England Journal of Medicine
Commentaries: Worrisome details noted in kids with COVID inflammatory syndrome – CIDRAP AND Researchers report nearly 300 cases of inflammatory syndrome tied to Covid-19 in kids – STAT
Opinion – Coronavirus: Could it be Burning out After 20% of a Population is Infected?
30 Jun, 2020 | 08:00h | UTCCoronavirus: could it be burning out after 20% of a population is infected? – The Conversation
Covid-19 Antibody Tests: A Briefing
26 Jun, 2020 | 09:17h | UTCCovid-19 antibody tests: a briefing – The BMJ
Commentary: Coronavirus: Antibody test lacks ‘proper assessment’ – BBC
Systematic Review: Antibody Tests for Identification of Current and Past Infection with SARS‐CoV‐2
26 Jun, 2020 | 09:19h | UTCAntibody tests for identification of current and past infection with SARS‐CoV‐2 – Cochrane Library
News Release: New Cochrane review assesses how accurate antibody tests are for detecting COVID-19 – Cochrane Library
Commentaries: New Cochrane review assesses how accurate antibody tests are for detecting COVID-19 – Wiley AND Expert reaction to Cochrane Review of antibody tests for SARS-CoV-2 – Science Media Centre AND Covid-19: Timing is critical for antibody tests, finds Cochrane review – The BMJ
Perspective: “I’m a Viral Immunologist. Here’s What Antibody Tests for Covid-19 Tell Us”
26 Jun, 2020 | 09:15h | UTCI’m a viral immunologist. Here’s what antibody tests for Covid-19 tell us – The Guardian
[Preprint] Intrafamilial Exposure to SARS-CoV-2 Induces Cellular Immune Response without Seroconversion
25 Jun, 2020 | 08:21h | UTCCommentary: Exposure to SARS-CoV-2 can induce virus-specific T cell responses without seroconversion – News Medical
A Compendium Answering 150 Questions on COVID‐19 and SARS‐CoV‐2
23 Jun, 2020 | 08:38h | UTCA compendium answering 150 questions on COVID‐19 and SARS‐CoV‐2 – Allergy
Study: Coronavirus Antibodies Can Disappear After a Few Months
21 Jun, 2020 | 23:46h | UTCClinical and immunological assessment of asymptomatic SARS-CoV-2 infections – Nature Medicine
Commentaries: Chinese study: Antibodies in COVID-19 patients fade quickly – CIDRAP AND Coronavirus antibodies may disappear 2 to 3 months after people recover, a new study found – Business Insider AND New insights can change everything we know about coronavirus antibodies – BGR – News Beezer AND Expert reaction to study looking at the immune response of 37 asymptomatic people with confirmed SARS-CoV-2 infection – Science Media Centre AND You May Have Antibodies After Coronavirus Infection. But Not for Long – The New York Times
The Science Behind the Search for a Covid-19 Vaccine
17 Jun, 2020 | 02:37h | UTCThe Science Behind the Search for a Covid-19 Vaccine – University of Melbourne
COVID-19 Vaccine Development Pipeline Gears Up
5 Jun, 2020 | 04:59h | UTCCOVID-19 vaccine development pipeline gears up – The Lancet
Perspective: Why a Vaccine May Not be Enough to End the Pandemic
4 Jun, 2020 | 04:54h | UTCWhy a vaccine may not be enough to end the pandemic – Vox
[Abstract Only] Analysis: Milk Allergy Guidelines May Cause Overdiagnosis in Babies and Children
3 Jun, 2020 | 03:33h | UTCMilk Allergy Guidelines may Cause Overdiagnosis in Babies and Children – Imperial College London
Original Study: Assessment of Evidence About Common Infant Symptoms and Cow’s Milk Allergy – JAMA Pediatrics (link to abstract – $ for full-text)
Cohort Study: Fexofenadine use During Pregnancy Does Not Appear to Be Associated with Increased Risk of Adverse Fetal Outcomes
3 Jun, 2020 | 03:31h | UTCAssociation Between Fexofenadine Use During Pregnancy and Fetal Outcomes – JAMA Pediatrics (free for a limited period)
SARS-CoV-2 Infection Protects Against Rechallenge in Rhesus Macaques
21 May, 2020 | 09:27h | UTCSARS-CoV-2 infection protects against rechallenge in rhesus macaques – Science
Related Study: DNA vaccine protection against SARS-CoV-2 in rhesus macaques – Science
Commentaries: Infection With SARS-CoV-2 Protects Against Re-infection – At Least in Rhesus Macaques – Technology Networks AND Prototype Vaccine Protects Monkeys From Coronavirus – The New York Times
Serology for SARS-CoV-2: Apprehensions, Opportunities, and the Path Forward
20 May, 2020 | 09:53h | UTCSerology for SARS-CoV-2: Apprehensions, opportunities, and the path forward – Science Immunology
Case Series: Hyperinflammatory Shock in Children During COVID-19 Pandemic
7 May, 2020 | 09:21h | UTCHyperinflammatory shock in children during COVID-19 pandemic – The Lancet
Commentaries: Researchers report “unprecedented cluster” of inflammatory problems in children amid pandemic – CNN AND Expert reaction to report on 8 children with hyperinflammatory shock during the COVID-19 pandemic – Science Media Centre AND Mysterious inflammatory syndrome in children potentially linked to COVID-19 reported in Montreal – National Post AND A New Coronavirus Threat to Children – The New York Times AND What to Know About Kawasaki Disease, the Pediatric Inflammatory Condition Possibly Linked to COVID-19 – TIME AND Kawasaki Disease—The Latest Weird Illness From Coronavirus – Forbes
Study: Development and Validation of a Penicillin Allergy Clinical Decision Rule
17 Mar, 2020 | 08:37h | UTCDevelopment and Validation of a Penicillin Allergy Clinical Decision Rule – JAMA Internal Medicine (free for a limited period)
FDA Safety Alert: Montelukast May Cause Serious Mental Health Side Effects
6 Mar, 2020 | 10:22h | UTCCommentary: Montelukast to Get Boxed Warning – NEJM Journal Watch (free)
[Abstract Only] Randomized Trial: Metformin May Reduce Metabolic Complications and Inflammation in Patients on Systemic Glucocorticoid Therapy
27 Feb, 2020 | 08:34h | UTCMetformin to reduce metabolic complications and inflammation in patients on systemic glucocorticoid therapy: a randomised, double-blind, placebo-controlled, proof-of-concept, phase 2 trial – The Lancet Diabetes & Endocrinology (link to abstract – $ for full-text)
Commentaries: Metformin could mitigate glucocorticoid-related complications – Medicine Matters (free) AND Metabolic effects of glucocorticoids reversed with metformin – Healio (free registration required) AND Diabetes Drug May Benefit Long-Term Steroid Users – MedPage Today (free registration required)