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Randomized Trial: Laparoscopic Cholecystectomy vs. Percutaneous Catheter Drainage for Acute Cholecystitis in High Risk Patients

11 Oct, 2018 | 21:32h | UTC

Laparoscopic cholecystectomy versus percutaneous catheter drainage for acute cholecystitis in high risk patients (CHOCOLATE): multicentre randomised clinical trial – The BMJ (free)

“Laparoscopic cholecystectomy compared with percutaneous catheter drainage reduced the rate of major complications in high risk patients with acute cholecystitis.”

 


Meta-Analysis: Statins Not Benefitial for Noncardiovascular Outcomes

11 Oct, 2018 | 21:31h | UTC

Statins and Multiple Noncardiovascular Outcomes: Umbrella Review of Meta-analyses of Observational Studies and Randomized Controlled Trials – Annals of Internal Medicine (link to abstract – $ for full-text)

Commentaries: Statin Benefits: Yes for CVD but No for Everything Else, Says New Review – TCTMD (free) AND Statins’ benefits beyond heart health aren’t clear-cut, analysis says – CNN (free)

 


ESMO Updated Clinical Practice Guidelines

11 Oct, 2018 | 20:12h | UTC

Supplement: ESMO Updated Clinical Practice Guidelines – European Society of Medical Oncology (free)

 


New ADA Guideline: Management of Hyperglycemia in Type 2 Diabetes

11 Oct, 2018 | 20:13h | UTC

Management of Hyperglycemia in Type 2 Diabetes, 2018. A Consensus Report by the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD) – Diabetes Care (free PDF)

Commentaries: New Consensus Report from the American Diabetes Association® (ADA) and the European Association for the Study of Diabetes (EASD) Calls for Paradigm Shift to Patient-Centered Care for Type 2 Diabetes – American Diabetes Association (free) AND New EASD-ADA consensus guidelines on managing hyperglycaemia in type 2 diabetes launched at EASD meeting – Diabetologia (free)

Related Guidelines: WHO Guideline: Medicines for the Treatment of Diabetes in Low-Resource Settings (free guideline and commentaries) AND Pharmacologic Glycemic Management of Type 2 Diabetes in Adults – Canadian Journal of Diabetes (free) ADA 2018 Standards of Medical Care in Diabetes (free guideline and commentaries) AND ACP Guideline: Hemoglobin A1c Targets for Glycemic Control in Type 2 Diabetes (free guideline and commentaries)

 


Perspective: What the Tests Don’t Show

11 Oct, 2018 | 20:11h | UTC

What the tests don’t show – The Washington Post (a few articles per month are free)

“Many doctors are surprisingly bad at reading test results and/or fail to grasp how false positives work. This is putting patients at risk” (via @pash22 see Tweet)

 


Perspective: Why Employers Should Stop Giving Away Snacks

11 Oct, 2018 | 20:10h | UTC

Why Employers Should Stop Giving Away Snacks – Pacific Standart (free)

Source: Global Health NOW Newsletter

 


Study: Outpatient Antibiotics Widely Prescribed Without an Infection Diagnosis

11 Oct, 2018 | 20:10h | UTC

Outpatient antibiotics widely prescribed without an infection diagnosis – CIDRAP (free)

Related Commentary: Study Finds Almost Half of Antibiotic Prescriptions Written Without a Diagnosis – Pharmacy Times (free)

 


COPD Guidelines: A Review of the 2018 GOLD Report

11 Oct, 2018 | 20:07h | UTC

COPD Guidelines: A Review of the 2018 GOLD Report – Mayo Clinic Proceedings (free)

Related: Highlights from the New GOLD COPD Guidelines (free guideline and commentaries)

 


Review: The Diagnosis and Treatment of Anxiety Disorders

11 Oct, 2018 | 20:09h | UTC

The Diagnosis and Treatment of Anxiety Disorders – Deutsches Ärzteblatt international (free)

 


Review: Cardiovascular Disease and COPD

11 Oct, 2018 | 20:08h | UTC

Cardiovascular disease and COPD: dangerous liaisons? – European Respiratory Review (free)

 


Randomized Trial: Effectiveness of Online vs In-Person Care for Adults With Psoriasis

11 Oct, 2018 | 20:06h | UTC

Effectiveness of Online vs In-Person Care for Adults With Psoriasis: A Randomized Clinical Trial – JAMA Network Open (free)

Commentary: Treating psoriasis in the future could be as easy as going online – USC News (free)

 


Randomized Trial: Closed-Loop Insulin Delivery in Suboptimally Controlled Type 1 Diabetes

11 Oct, 2018 | 20:06h | UTC

Closed-loop insulin delivery in suboptimally controlled type 1 diabetes: a multicentre, 12-week randomised trial – The Lancet (free)

Commentaries: Enlarging the loop: closed-loop insulin delivery for type 1 diabetes – The Lancet (free) AND Hybrid Closed Loop System Aid for Tighter Glucose Control – MedPage Today (free registration required)

 


CDC Report: Sexually Transmitted Disease Surveillance 2017

11 Oct, 2018 | 20:04h | UTC

Sexually Transmitted Disease Surveillance 2017 – Centers for Disease Control and Prevention (free)

Commentaries: Sexually transmitted infections are at an all-time high. Urgent action is needed – STAT (free)

 


Perspective: Move To Population Health Hits Hospital Finances

11 Oct, 2018 | 20:03h | UTC

Move To Population Health Hits Hospital Finances – Forbes (free)

 


European Position Statement on Diagnosis, and Treatment of Meniere’s Disease

11 Oct, 2018 | 20:03h | UTC

European Position Statement on Diagnosis, and Treatment of Meniere’s Disease – The Journal of International Advanced Otology (free PDF)

 


Outcome Reporting Bias in Trials: A Methodological Approach for Assessment and Adjustment in Systematic Reviews

11 Oct, 2018 | 20:02h | UTC

Outcome reporting bias in trials: a methodological approach for assessment and adjustment in systematic reviews – The BMJ (free)

 


Meta-Analysis: Association of Levels of Physical Activity With Risk of Parkinson Disease

11 Oct, 2018 | 20:02h | UTC

Association of Levels of Physical Activity With Risk of Parkinson Disease: A Systematic Review and Meta-analysis – JAMA Network Open (free)

Commentaries: Physical Activity and Parkinson Disease Risk: An Intriguing Link – JAMA Network Open (free) AND Physical Activity Could Reduce Risk of Parkinson disease, esp. in Men – MedicalResearch.com (free)

 


Study: Incidence of Progression of Persistent Non-Dysplastic Barrett’s Esophagus to Malignancy

11 Oct, 2018 | 20:01h | UTC

Incidence of Progression of Persistent Non-Dysplastic Barrett’s Esophagus to Malignancy – Clinical Gastroenterology and Hepatology (link to abstract – $ for full-text)

Commentary: Patients with stable Barrett’s esophagus may need less surveillance, study finds – ACP Gastroenterology (free)

 


Perspective: An Endless One-sided Confidence in Pip-tazo?

11 Oct, 2018 | 20:00h | UTC

An endless one-sided confidence in Pip-tazo? – Reflections on Infection Prevention and Control (free)

Original Trial: Randomized Trial: Piperacillin-Tazobactam vs for Patients With E coli or Klebsiella pneumoniae Bloodstream Infection and Ceftriaxone Resistance (link to abstract and commentaries)

 


Study: Acceleration of BMI in Early Childhood and Risk of Sustained Obesity

5 Oct, 2018 | 02:45h | UTC

Acceleration of BMI in Early Childhood and Risk of Sustained Obesity – New England Journal of Medicine (link to abstract – $ for full-text)

Quick Take Video Summary: Childhood BMI Acceleration and Sustained Obesity (free)

Commentary: BMI in Early Childhood and Sustained Obesity – American College of Cardiology (free)

 


Perspective: Given Their Potential for Harm, It’s Time to Focus on the Safety of Supplements

5 Oct, 2018 | 02:41h | UTC

Given Their Potential for Harm, It’s Time to Focus on the Safety of Supplements – JAMA (free for a limited period) (via @NUNESDOC)

“About 23 000 visits to emergency departments each year can be attributed to adverse events from dietary supplements.”

 


Meta-Analysis: Effects of Vitamin D Supplementation on Musculoskeletal Health

5 Oct, 2018 | 02:44h | UTC

Effects of vitamin D supplementation on musculoskeletal health: a systematic review, meta-analysis, and trial sequential analysis – The Lancet Diabetes & Endocrinology (link to abstract – $ for full-text)

Commentaries: The Lancet Diabetes & Endocrinology: Vitamin D supplementation in adults does not prevent fractures, falls or improve bone mineral density – The Lancet (free) AND Vitamin D supplements don’t help bone health, major study concludes – The Guardian (free) AND Millions of Americans take vitamin D. Most should just stop – VOX (free)

Related: Vitamin D, the Sunshine Supplement, Has Shadowy Money Behind It (free commentaries and NICE Guideline) AND Vitamin D Not Linked to Fracture Risk (free study and commentaries)

 


Study: Effect of Lorcaserin on Prevention and Remission of Type 2 Diabetes in Overweight and Obese Patients

5 Oct, 2018 | 02:38h | UTC

Effect of lorcaserin on prevention and remission of type 2 diabetes in overweight and obese patients (CAMELLIA-TIMI 61): a randomised, placebo-controlled trial – The Lancet (link to abstract – $ for full-text)

Commentaries: Weight loss drug shows positive effect on diabetes – Brigham and Women’s Hospital (free) AND Weight Loss Drug Helped Prevent Diabetes in Overweight People – MedPage Today (free registration required)

Related Article: Cardiovascular Safety of Lorcaserin in Overweight or Obese Patients (link to abstract and commentaries)

 


Clinical Update: Immune Checkpoint Inhibitor Toxicity in 2018

5 Oct, 2018 | 02:42h | UTC

Immune Checkpoint Inhibitor Toxicity in 2018 – JAMA (free for a limited period)

Related Guidelines: Management of Immune-Related Adverse Events in Patients Treated With Immune Checkpoint Inhibitor Therapy: American Society of Clinical Oncology Clinical Practice Guideline (free) AND Managing toxicities associated with immune checkpoint inhibitors: consensus recommendations from the Society for Immunotherapy of Cancer (SITC) Toxicity Management Working Group (free)

Related Review: New drugs, new toxicities: severe side effects of modern targeted and immunotherapy of cancer and their management – Critical Care (free)

 


Report: The Future of Healthcare

5 Oct, 2018 | 02:39h | UTC

The future of healthcare – The Economist (free PDF)

 


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