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New Cochrane Handbook for Systematic Reviews of Interventions
3 Oct, 2019 | 01:35h | UTCCochrane Handbook for Systematic Reviews of Interventions – Version 6, 2019 – Cochrane Library (free chapters)
Cochrane News Releases: New Cochrane Handbook for Systematic Reviews of Interventions (free) What you need to know about the new Cochrane Handbook (free)
Study: Vaping-Associated Lung Injury Represents a Form of Airway-centered Chemical Pneumonitis
3 Oct, 2019 | 01:15h | UTCPathology of Vaping-Associated Lung Injury – New England Journal of Medicine (free)
Commentaries: Vaping-related lung injuries resemble chemical burns, study finds – STAT (free) AND U.S. doctors rule out pneumonia due to inhaled oil as cause of vaping injuries – Reuters (free) AND Lung Damage From Vaping Resembles Chemical Burns, Report Says – The New York Times (10 articles per month are free)
Related: CDC Report: 76.9% of Patients with Vaping-related Lung Illnesses Used a THC-Containing Product (free) AND Preliminary Report: Pulmonary Illness Related to E-Cigarette Use (free)
Related Commentary on Twitter
New letter describes 17 patients, all of whom vaped, who had lung biopsies after presenting with symptoms and bilateral pulmonary opacities that led to a clinical diagnosis of #vaping-associated lung injury. https://t.co/n5rF2OOOwq
— NEJM (@NEJM) October 2, 2019
Meta-Analysis: Carotid Artery Stenting vs. Carotid Endarterectomy
3 Oct, 2019 | 01:12h | UTC
Study: Antidepressant use During Pregnancy Linked to Increased Risk of Gestational Diabetes
3 Oct, 2019 | 01:08h | UTCCommentaries: Antidepressants linked to heightened pregnancy related diabetes risk – BMJ (free) AND Antidepressants linked to risk of gestational diabetes – OnMedica (free) AND Antidepressants are linked to a higher gestational diabetes risk in a new study – CNN (free)
Systematic Review: Association of Antidepressant Use with Adverse Health Outcomes
3 Oct, 2019 | 01:03h | UTCAssociation of Antidepressant Use With Adverse Health Outcomes: A Systematic Umbrella Review – JAMA Psychiatry (free for a limited period)
Editorial: Selective Serotonin Reuptake Inhibitor Use During Pregnancy—Associated With but Not Causative of Autism in Offspring (free for a limited period)
Commentaries: Antidepressant medications appear to be generally safe,study suggests – Linköping University (free) AND Expert reaction to study on association of antidepressant use with adverse health outcomes – Science Media Centre (free)
How to Improve Healthcare Improvement—an essay by Mary Dixon-Woods
2 Oct, 2019 | 22:24h | UTCHow to improve healthcare improvement—an essay by Mary Dixon-Woods – The BMJ (free)
Consensus Statement: Unmet Therapeutic, Educational and Scientific Needs in Parathyroid Disorders
2 Oct, 2019 | 22:25h | UTC
[Abstract Only] Randomized Trial: Low-FODMAP Diet is Safe and Effective for Managing Persistent Gut Symptoms in Patients with Inflammatory Bowel Disease
2 Oct, 2019 | 22:23h | UTCEffects of Low-FODMAP Diet on Symptoms, Fecal Microbiome, and Markers of Inflammation in Patients With Quiescent Inflammatory Bowel Disease in a Randomized Trial – Gastroenterology (link to abstract – $ for full-text)
Commentary: FODMAPs diet relieves symptoms of inflammatory bowel disease – King’s College London (free)
ATS/IDSA Guideline: Diagnosis and Treatment of Adults with Community-acquired Pneumonia
2 Oct, 2019 | 02:14h | UTCNews Release: ATS/IDSA publishes clinical guideline on community acquired pneumonia – American Thoracic Society (free)
See also: Executive Summary (free PDF)
Study: Male Infertility Linked to Increased Risk of Prostate Cancer
2 Oct, 2019 | 22:20h | UTCEditorial: Male infertility linked to risk of prostate cancer (free)
Commentaries: Assisted reproduction and risk of prostate cancer for men – The BMJ Opinion (free) AND Fathering children by assisted reproduction linked to increased risk of prostate cancer – The BMJ (free) AND Male infertility linked to prostate cancer risk – BBC (free) AND Male infertility linked to increased prostate cancer risk – NHS Choices (free)
[Abstract Only] Randomized Trial: Monoclonal Antibody for Patients with Severe Chronic Rhinosinusitis with Nasal Polyps
2 Oct, 2019 | 22:17h | UTCEfficacy and safety of dupilumab in patients with severe chronic rhinosinusitis with nasal polyps (LIBERTY NP SINUS-24 and LIBERTY NP SINUS-52): results from two multicentre, randomised, double-blind, placebo-controlled, parallel-group phase 3 trials – The Lancet (link to abstract – $ for full-text)
Related Commentary on Twitter
NEW Research—Efficacy & safety of dupilumab in patients w/ severe chronic #rhinosinusitis w/ #nasalpolyps (LIBERTY NP SINUS-24 & LIBERTY NP SINUS-52): results from two multicentre, randomised, double-blind, placebo-controlled, parallel-group phase 3 trials https://t.co/YH5khPeHxz pic.twitter.com/PR12UBV6Kf
— The Lancet (@TheLancet) September 20, 2019
Review: Health Problems in Healthcare Workers
2 Oct, 2019 | 22:19h | UTCHealth problems in healthcare workers: A review – Journal of Family Medicine and Primary Care (free)
Related: Whole-system approaches to improving the health and wellbeing of healthcare workers: A systematic review – PLOS One (free) AND Healthcare Staff Wellbeing, Burnout, and Patient Safety: A Systematic Review – PLOS One (free)
Guidelines for the Surgical Management of Chronic Lateral Ankle Instability
2 Oct, 2019 | 22:21h | UTC
Consensus Statement: Concussion Management in Combat Sports
2 Oct, 2019 | 22:18h | UTC
[Abstract Only] Meta-Analysis: Povidone-iodine 1% is the Most Effective Vaginal Antiseptic for Preventing Post-cesarean Endometritis
2 Oct, 2019 | 22:16h | UTCPovidone-iodine 1% is the most effective vaginal antiseptic for preventing post-cesarean endometritis: a systematic review and network meta-analysis – American Journal of Obstetrics & Gynecology (link to abstract – $ for full-text)
Source: EvidenceAlerts
AL Amyloidosis for the Cardiologist and Oncologist: Epidemiology, Diagnosis, and Management
2 Oct, 2019 | 22:15h | UTCRelated: Cardiac Amyloidosis: Updates in Imaging (several reviews on the subject)
Meta-Analysis: Healthy Dietary Patterns and Incidence of Chronic Kidney Disease
2 Oct, 2019 | 02:12h | UTCCommentaries: A healthy diet may help prevent kidney disease – American Society of Nephrology (free) AND Healthy Diet May Prevent CKD, Albuminuria – Renal & Urology News (free) AND Patient Voice: Diet Patterns and Kidney Disease – Clinical Journal of the American Society of Nephrology (free)
Systematic Review: Can People Stop Smoking by Cutting Down the Amount they Smoke First?
2 Oct, 2019 | 01:51h | UTCSmoking reduction interventions for smoking cessation – Cochrane Library (free)
Summary: Can people stop smoking by cutting down the amount they smoke first? – Cochrane Library (free)
Review: Chronic Kidney Disease Diagnosis and Management
2 Oct, 2019 | 02:06h | UTCChronic Kidney Disease Diagnosis and Management: A Review – JAMA (free for a limited period)
Special Issue: Obstetric Anesthesia
2 Oct, 2019 | 02:08h | UTCObstetric Anaesthesia – Update in Anaesthesia (free articles)
– Homepage
– Obstetric anaesthesia in resource limited settings
– General anesthesia for elective cesarean section in resource-limited settings
– Obstetric spinal anaesthesia
– Management of total spinal block in obstetrics
– Labour epidural troubleshooting
– Establishing an epidural service for labour analgesia in a variable resource environment
– Emergency management of maternal collapse and arrest
– Pre-eclampsia – prevention, diagnosis and management
– Placental pathology: a review of placenta previa, placental abruption and placenta accreta
– Anaesthetic implications of morbid obesity in pregnancy
– Update in obstetric trauma management
– Update in obstetric maternal sepsis
– Obstetric and foetal physiology
– Anaesthesia for non obstetric surgery during pregnancy
Source: Critical Care Reviews Newsletter
Meat’s Bad for You! No, It’s Not! How Experts See Different Things in the Data
2 Oct, 2019 | 02:02h | UTCMeat’s Bad for You! No, It’s Not! How Experts See Different Things in the Data – The New York Times (10 articles per month are free)
See also: Is eating beef healthy? The new fight raging in nutrition science, explained. – Vox (free)
Original Article: Guideline: It Is NOT Necessary to Reduce Red and Processed Meat Consumption (free guideline and commentaries)
[Abstract Only] Cohort Study: Cool Running Water First Aid Decreases Skin Grafting Requirements in Pediatric Burns
2 Oct, 2019 | 01:53h | UTCCool Running Water First Aid Decreases Skin Grafting Requirements in Pediatric Burns: A Cohort Study of Two Thousand Four Hundred Ninety-five Children – Annals of Emergency Medicine (link to abstract – $ for full-text)
Commentary: Simple Cool Running Water Reduces Burn Severity in Children – Journal Feed (free)
Guidelines for Diagnostic Flexible Bronchoscopy in Adults
2 Oct, 2019 | 01:33h | UTCRelated Guidelines: British Thoracic Society guideline for diagnostic flexible bronchoscopy in adults: accredited by NICE – Thorax (free) AND ERS statement: interventional bronchoscopy in children – European Respiratory Journal (free)
Randomized Trial: Conflicting Results in Small Trial Testing Vitamin C for Sepsis and Severe Acute Respiratory Failure, Further Trials are Required
2 Oct, 2019 | 02:04h | UTCEffect of Vitamin C Infusion on Organ Failure and Biomarkers of Inflammation and Vascular Injury in Patients With Sepsis and Severe Acute Respiratory Failure: The CITRIS-ALI Randomized Clinical Trial – JAMA (free for a limited period)
Editorial: Is High-Dose Vitamin C Beneficial for Patients With Sepsis? (free)
Commentary: ‘Tantalizing’ Results For A Test Of Vitamin C For Sepsis – NPR (free)
In exploratory analyses that did not adjust for multiple comparisons, 3 secondary outcomes (out of 46 examined) were significantly different between groups. At day 28, mortality was 46.3% (38/82) in the placebo group vs 29.8% (25/84) in the vitamin C group (P = .03). The number of ICU-free days to day 28 was 10.7 in the vitamin C group vs 7.7 in the placebo group (P = .03). The number of hospital-free days in the vitamin C group vs the placebo group was 22.6 vs 15.5, respectively (P = .04).
[Abstract Only] Randomized Trial: Triple Therapy Inhaler for Uncontrolled Asthma
2 Oct, 2019 | 01:45h | UTCSingle inhaler extrafine triple therapy in uncontrolled asthma (TRIMARAN and TRIGGER): two double-blind, parallel-group, randomised, controlled phase 3 trials – The Lancet (link to abstract – $ for full-text)
Commentaries: Asthma 3-in-1 Therapy May Improve Lung Function, Study Shows – The New York Times (10 articles per month are free) AND Triple-Therapy Inhaler Tied to Better Lung Function in Asthma – NEJM Journal Watch (free)