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Meta-Analysis of Direct Oral Anticoagulants Randomized Trials: Double vs. Triple Antithrombotic Therapy in Patients with Atrial Fibrillation Following Percutaneous Coronary Intervention
22 Jan, 2020 | 09:28h | UTCRelated: Meta-analysis: Double Anti-thrombotic Therapy Safer than Triple Therapy in Patients with Atrial Fibrillation and Coronary Artery Disease (studies on the subject)
Review: Enhancing Recovery in Pediatric Major Abdominal Surgery
22 Jan, 2020 | 09:26h | UTCRelated Reviews: Review of the enhanced recovery pathway for children: perioperative anesthetic considerations – Canadian Journal of Anesthesia (free) AND Embracing change: the era for pediatric ERAS is here – Pediatric Surgery International (free) AND Preparing Enhanced Recovery After Surgery for implementation in pediatric populations – Journal of Pediatric Surgery (free)
Opinion: Our Best Weapons Against Cancer are Not Magic Bullets
22 Jan, 2020 | 09:23h | UTCOur best weapons against cancer are not magic bullets – Nature (free)
[Abstract Only] Systematic Review: No Benefit from Flexible Titration Above Minimum Licensed Dose in Prescribing Antidepressants for Major Depression
22 Jan, 2020 | 09:27h | UTCNo benefit from flexible titration above minimum licensed dose in prescribing antidepressants for major depression: systematic review – Acta Psychiatrica Scandinavica (link to abstract – $ for full-text)
Related Meta-analysis: Optimal Dose of Antidepressants in Major Depression – The Lancet Psychiatry (free study and commentaries)
Systematic Review: Treatments for Preventing Recurrence of Infection with Pseudomonas Aeruginosa in People with Cystic Fibrosis
22 Jan, 2020 | 09:22h | UTCTreatments for preventing recurrence of infection with Pseudomonas aeruginosa in people with cystic fibrosis – Cochrane Library (free)
Summary: Treatments for preventing recurrence of infection with Pseudomonas aeruginosa in people with cystic fibrosis – Cochrane Library (free)
Systematic Review: Interventions for Chronic Palmoplantar Pustulosis
22 Jan, 2020 | 09:21h | UTCInterventions for chronic palmoplantar pustulosis – Cochrane Library (free)
Summary: Treating long-term palmoplantar pustulosis (pustules on the hands and feet) – Cochrane Library (free)
Glucocorticoids in Elite Sport: Current Status, Controversies and Innovative Management Strategies
22 Jan, 2020 | 09:17h | UTC
Perspective – Childhood Obesity Is a Major Problem. Research Isn’t Helping.
22 Jan, 2020 | 09:20h | UTCChildhood Obesity Is a Major Problem. Research Isn’t Helping. – The New York Times (10 articles per month are free)
“Something is missing with many study methods.”
Cohort Study: Second-generation Antipsychotics and Pregnancy Complications
22 Jan, 2020 | 09:18h | UTC
Immune Checkpoint Inhibitor Myocarditis: Pathophysiological Characteristics, Diagnosis, and Treatment
22 Jan, 2020 | 09:15h | UTCRelated: Cardiotoxicity of immune checkpoint inhibitors – ESMO Open (free) AND Cardiotoxicity from immune checkpoint inhibitors – IJC Heart & Vasculature (free) AND Cardiovascular toxicity of immune checkpoint inhibitors in cancer patients: A review when cardiology meets immuno-oncology – Journal of the Formosan Medical Association (free) AND Immune-Checkpoint Inhibitor-Induced Fulminant Myocarditis and Cardiogenic Shock – JACC: CardioOncology (free)
Study: Concurrent Prenatal Drinking and Smoking Increases Risk for Sudden Infant Death Syndrome
22 Jan, 2020 | 09:18h | UTCCommentary: Combined prenatal smoking and drinking greatly increases SIDS risk – NIH News Releases (free)
Becoming a Parent: A Systematic Review and Meta‐analysis of Changes in BMI, Diet, and Physical Activity
22 Jan, 2020 | 09:13h | UTC
[Abstract Only] Randomized Trial: Effects of Addition of Anti-thymocyte Globulin to Standard Graft-versus-host Disease Prophylaxis in Patients with Hematological Malignancies Undergoing Transplantation from Unrelated Donor
22 Jan, 2020 | 09:16h | UTCAddition of anti-thymocyte globulin to standard graft-versus-host disease prophylaxis versus standard treatment alone in patients with haematological malignancies undergoing transplantation from unrelated donors: final analysis of a randomised, open-label, multicentre, phase 3 trial – The Lancet Haematology (link to abstract – $ for full-text)
Randomized Trial: Efficacy of Glecaprevir and Pibrentasvir in Patients with Chronic HCV Genotype 1 Patients After Treatment Failure with NS5A Inhibitor Plus Sofosbuvir Therapy
22 Jan, 2020 | 09:11h | UTCEditorial: Retreatment Options for Patients Who Failed Direct-Acting Antiviral Regimens Containing NS5A Inhibitors: Is Glecaprevir/Pibrentasvir a Valid and Robust Option? (free)
Source: EvidenceAlerts
Related Commentary on Twitter
16 weeks treatment with G/P produced sustained virologic response 12 weeks after treatment in >90% of chronic #HCV genotype 1 patients https://t.co/YGM81urXpm pic.twitter.com/g1OtzeKQsL
— Gastroenterology (@AGA_Gastro) November 27, 2019
Perspective: Telemedicine, eConsults, and Other Remote ID Clinical Services Make So Much Sense — Why Isn’t Everyone Doing it?
22 Jan, 2020 | 09:12h | UTC
[Abstract Only] Randomized Trial: Effectiveness of Mirtazapine as Add-on to Paroxetine vs. Paroxetine or Mirtazapine Monotherapy in Patients with Depression with Early Non-response to Paroxetine
22 Jan, 2020 | 09:08h | UTCEffectiveness of mirtazapine as add-on to paroxetine v. paroxetine or mirtazapine monotherapy in patients with major depressive disorder with early non-response to paroxetine: a two-phase, multicentre, randomized, double-blind clinical trial – Psychological Medicine (link to abstract – $ for full-text)
Randomized Trial: Methotrexate Effect on Immunogenicity and Long-term Maintenance of Adalimumab in Axial Spondyloarthritis
22 Jan, 2020 | 09:10h | UTC
Palliative Sedation: A Safety Net for the Relief of Refractory and Intolerable Symptoms at the End of Life
22 Jan, 2020 | 09:06h | UTC
Top 10 Best Cities for Medical Tourists in 2020
22 Jan, 2020 | 09:07h | UTCPatients Beyond Borders Announces Top 10 Best Cities for Medical Tourists in 2020 (free)
Amniotic Fluid Embolism: Principles of Early Clinical Management
22 Jan, 2020 | 09:02h | UTC
Pain and Delirium: Mechanisms, Assessment, and Management
22 Jan, 2020 | 09:04h | UTCPain and delirium: mechanisms, assessment, and management – European Geriatric Management (free)
WHO: Smoking Greatly Increases Risk of Complications After Surgery
21 Jan, 2020 | 03:15h | UTCSmoking greatly increases risk of complications after surgery – World Health Organization (free)
See also: Tobacco and Surgical outcomes: WHO Knowledge Summary
As Coronavirus Outbreak Surges In China, WHO Calls For Emergency Meeting
21 Jan, 2020 | 03:12h | UTCAs Coronavirus Outbreak Surges In China, WHO Calls For Emergency Meeting – Health Policy Watch (free)
See also: WHO calls for emergency meeting on new virus in China, as cases spread to health care workers – STAT (free) AND China Confirms New Coronavirus Spreads From Humans to Humans – The New York Times (10 articles per month are free) AND AND As virus spreads to more Chinese cities, WHO calls emergency meeting – Reuters (free)
Related: New Chinese virus ‘will have infected hundreds’ (free resources)
Podcast: Lipids Update and Cardiovascular Risk Reduction
21 Jan, 2020 | 03:10h | UTCSee also: Episode List
Synthesis Without Meta-analysis (SWiM) in Systematic Reviews: Reporting Guideline
21 Jan, 2020 | 03:11h | UTCSynthesis without meta-analysis (SWiM) in systematic reviews: reporting guideline – The BMJ (free)
Commentary: Hilary Thomson: Grasping the nettle of narrative synthesis – The BMJ Opinion (free)