All Posts
Review: Mortality Prediction Models in the Adult Critically Ill
23 Jan, 2020 | 02:04h | UTC
[Abstract Only] Study: Patients with Myocardial Infarction and Low-Normal (90% to 94%) Oxygen Saturation Do Not Benefit from Oxygen Therapy
23 Jan, 2020 | 02:07h | UTCCommentary: Oxygen of No Benefit, Even in MI Patients With Low-Normal Saturation – TCTMD (free)
Related: Systematic Review: Higher vs. Lower Fraction of Inspired Oxygen or Targets of Arterial Oxygenation for Adults Admitted to the Intensive Care Unit (several studies on the subject)
[Abstract Only] Randomized Trial: Polypectomy During the Insertion Phase vs. During Withdrawal Phase of Colonoscopy
23 Jan, 2020 | 02:03h | UTCClinical importance of cold polypectomy during the insertion phase in the left side of the colon and rectum: a multicenter randomized controlled trial (PRESECT STUDY) – Gastrointestinal Endoscopy (link to abstract – $ for full-text)
ASCO Guideline: Molecular Biomarkers in Localized Prostate Cancer
23 Jan, 2020 | 02:00h | UTCMolecular Biomarkers in Localized Prostate Cancer: ASCO Guideline – Journal of Clinical Oncology (free)
Evidence-based Guidelines on the Therapeutic use of Repetitive Transcranial Magnetic Stimulation
23 Jan, 2020 | 02:05h | UTC
Study: Efficacy of Azithromycin in Severe Asthma from the AMAZES Randomized Trial
23 Jan, 2020 | 01:58h | UTCEfficacy of azithromycin in severe asthma from the AMAZES randomised trial – ERJ Open Research (free)
Original Study: Effect of azithromycin on asthma exacerbations and quality of life in adults with persistent uncontrolled asthma (AMAZES): a randomised, double-blind, placebo-controlled trial – The Lancet (link to abstract and commentary)
ASCO Guideline: Lung Cancer Surveillance After Definitive Curative-Intent Therapy
23 Jan, 2020 | 02:01h | UTC
[Abstract Only] Randomized Controlled Trial of Advance Care Planning Video Decision Aid for the General Population
23 Jan, 2020 | 01:53h | UTCRandomized Controlled Trial of Advance Care Planning Video Decision Aid for the General Population – Journal of Pain and Symptom Management (link to abstract – $ for full-text)
Systematic Review: Tonsillectomy for Periodic Fever, Aphthous Stomatitis, Pharyngitis and Cervical Adenitis Syndrome
23 Jan, 2020 | 01:57h | UTCTonsillectomy for periodic fever, aphthous stomatitis, pharyngitis and cervical adenitis syndrome (PFAPA) – Cochrane Library (free)
Summary: Tonsillectomy for PFAPA syndrome (a rare cause of recurrent fever, mouth ulcers, sore throat and swollen neck glands) – Cochrane Library (free)
[Abstract Only] Meta-Analysis: Endovascular vs. Open Repair for Abdominal Aortic Aneurysm
23 Jan, 2020 | 01:55h | UTCEndovascular vs. Open Repair for Abdominal Aortic Aneurysm: Systematic Review and Meta-analysis of Updated Peri-operative and Long Term Data of Randomised Controlled Trials – European Journal of Vascular & Endovascular Surgery (link to abstract – $ for full-text)
Consensus Guidelines for Perioperative Management of Patients for Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy
23 Jan, 2020 | 01:52h | UTC
Summary: Current AATS Guidelines on Surgical Treatment of Infective Endocarditis
23 Jan, 2020 | 01:54h | UTCOriginal Guideline: 2016 The American Association for Thoracic Surgery (AATS) consensus guidelines: Surgical treatment of infective endocarditis: Executive summary (free)
Related Guidelines: Infective Endocarditis in Adults: Diagnosis, Antimicrobial Therapy, and Management of Complications: A Scientific Statement for Healthcare Professionals From the American Heart Association (free) AND 2015 ESC Guidelines for the management of infective endocarditis (free)
[Abstract Only] Randomized Trial: Fenfluramine Hydrochloride for the Treatment of Seizures in Dravet Syndrome
23 Jan, 2020 | 01:49h | UTCFenfluramine hydrochloride for the treatment of seizures in Dravet syndrome: a randomised, double-blind, placebo-controlled trial – The Lancet (link to abstract – $ for full-text)
Commentaries: Drug could reduce frequency of seizures for children with Dravet Syndrome – The Lancet (free) AND Old drug offers new hope for children with devastating disorder – World Pharma News (free)
Review: Lifetime Cardiovascular Management of Patients with Previous Kawasaki Disease
23 Jan, 2020 | 01:51h | UTCLifetime cardiovascular management of patients with previous Kawasaki disease – Heart (free)
Randomized Trial: Treatments for Neovascular Age-Related Macular Degeneration Compared
23 Jan, 2020 | 01:50h | UTC
[Abstract Only] Randomized Trial: Cabazitaxel vs. Abiraterone or Enzalutamide in Metastatic Prostate Cancer
23 Jan, 2020 | 01:48h | UTCCabazitaxel versus Abiraterone or Enzalutamide in Metastatic Prostate Cancer – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: ESMO 2019: Cabazitaxel vs Abiraterone or Enzalutamide in Previously Treated Metastatic Castration-Resistant Prostate Cancer – The ASCO Post (free)
Related Commentary on Twitter
#VisualAbstract: Cabazitaxel in Metastatic Prostate Cancer. See more NEJM Visual Abstracts now: pic.twitter.com/nUeb6dqRYi
— NEJM (@NEJM) December 26, 2019
ACR/NKF Consensus Statement: “The Risk of Acute Kidney Injury Developing in Patients with Reduced Kidney Function Following Exposure to Intravenous Iodinated Contrast Media has Been Overstated”
22 Jan, 2020 | 09:44h | UTCCommentary: Risk of kidney injury in contrast CT imaging overstated, experts say – UPI (free)
Related: Another Study Questions the Association of Contrast Use and Acute Kidney Injury (studies on the subject)
Position Paper: Diagnosis and Risk Stratification of Chest Pain Patients in the Emergency Department
22 Jan, 2020 | 09:43h | UTCDiagnosis and risk stratification of chest pain patients in the emergency department: focus on acute coronary syndromes. A position paper of the Acute Cardiovascular Care Association – European Heart Journal: Acute Cardiovascular Care (free for a limited period)
AHA Recommendations: Prehospital Activation of Hospital Resources in Patients with Suspected ST‐Segment–Elevation Myocardial Infarction
22 Jan, 2020 | 09:42h | UTC
WHO Q & A – E-cigarettes: How Risky Are They?
22 Jan, 2020 | 09:39h | UTCE-cigarettes: how risky are they? – World Health Organization (free)
Related Commentary on Twitter (Thread – Click for More)
E-cigarettes are harmful to health and are not safe.
They are particularly risky when used by adolescents. Nicotine is highly addictive & young people’s brains develop up to their mid-twenties. Exposure to nicotine can have long-lasting, damaging effects.https://t.co/S8ZHoux45e pic.twitter.com/mkx0d5GCpW— World Health Organization (WHO) (@WHO) January 21, 2020
CDC: First Travel-related Case of 2019 Novel Coronavirus Detected in United States
22 Jan, 2020 | 09:40h | UTCSee also: US detects first novel coronavirus case, in traveler – CIDRAP (free) AND China virus toll rises to nine as pandemic fears grow – Reuters (free) AND First US case of Wuhan coronavirus confirmed by CDC – CNN (free) AND How quickly does the Wuhan virus spread? – Nature (free)
[Abstract Only] Meta-Analysis: Treatment of Uncomplicated Acute Diverticulitis Without Antibiotics May be Safe
22 Jan, 2020 | 09:31h | UTCTreatment of Uncomplicated Acute Diverticulitis Without Antibiotics: A Systematic Review and Meta-analysis – Diseases of the Colon & Rectum (link to abstract – $ for full-text)
Related: Randomized Trial: Antibiotic Avoidance Associated with Similar Long-term Outcomes in Uncomplicated Diverticulitis (randomized trials on the subject)
Randomized Trial: Hydroxyethyl Starch vs. Saline for Volume Replacement Therapy in High-Risk Patients Undergoing Major Abdominal Surgery
22 Jan, 2020 | 09:36h | UTCEffect of Hydroxyethyl Starch vs Saline for Volume Replacement Therapy on Death or Postoperative Complications Among High-Risk Patients Undergoing Major Abdominal Surgery: The FLASH Randomized Clinical Trial – JAMA (free for a limited period)
Editorial: Hydroxyethyl Starch for Fluid Replacement Therapy in High-Risk Surgical Patients: Context and Caution (free for a limited period)
Related Cochrane Review: Colloids vs Crystalloids for Fluid Resuscitation in Critically Ill People (free)
Related Commentary on Twitter
FLASH trial published today in @JAMA_current, comparing saline versus HES in high risk surgical patients.https://t.co/5xet1jOtEA
Our accompanying editorial, which hopefully helps to contextualizing the results can be found at:https://t.co/Ebl9ieG5Sp— Fernando Zampieri (@f_g_zampieri) January 21, 2020
Randomized Trial: Renal Denervation + Catheter Ablation Reduces Recurrence Compared to Catheter Ablation Alone in Patients with Paroxysmal Atrial Fibrillation and Hypertension
22 Jan, 2020 | 09:34h | UTCEffect of Renal Denervation and Catheter Ablation vs Catheter Ablation Alone on Atrial Fibrillation Recurrence Among Patients with Paroxysmal Atrial Fibrillation and Hypertension: The ERADICATE-AF Randomized Clinical Trial – JAMA (free for a limited period)
Editorial: Improving Outcomes in Patients With Atrial Fibrillation and Hypertension (free for a limited period)
Managing Clinical Uncertainty: A Teachable Moment
22 Jan, 2020 | 09:33h | UTCManaging Clinical Uncertainty: A Teachable Moment – JAMA Internal Medicine (free for a limited period)