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WHO Pauses Hydroxychloroquine Arm Of COVID-19 Clinical Trial Due to Safety Concerns

26 May, 2020 | 09:35h | UTC

WHO Pauses Hydroxychloroquine Arm Of COVID-19 Clinical Trial – After Lancet Study Finds Higher Mortality Rate Among Patients Getting The Drug – Health Policy Watch

See also: WHO halts hydroxychloroquine trial for coronavirus amid safety fears – The Guardian AND WHO Halts Hydroxychloroquine Trial Over Safety Concerns – NPR

 


Opinion: The ‘Just Stay Home’ Message Will Backfire

26 May, 2020 | 09:33h | UTC

The ‘Just Stay Home’ Message Will Backfire – The Atlantic

“We need less extreme and more nuanced recommendations for navigating life during the pandemic.”

 

Related Commentary on Twitter

 


Analysis of Traumatic Brain Injury Lesions on Head CT Using Deep Learning

26 May, 2020 | 09:23h | UTC

Multiclass semantic segmentation and quantification of traumatic brain injury lesions on head CT using deep learning: an algorithm development and multicentre validation study – The Lancet Digital Health

Commentaries: Deep learning: a turning point in acute neurology – The Lancet Digital Health

AI successfully used to identify different types of brain injuries – University of Cambridge AND Deep learning automatically measures key features of TBI – Health Imaging

 


COVID-19 Disease and Ophthalmology: An Update

26 May, 2020 | 09:30h | UTC

COVID-19 Disease and Ophthalmology: An Update – Ophthalmology and Therapy

Related: Characteristics of Ocular Findings of Patients With Coronavirus Disease

 


Clinical Guidance: Intravenous Fluid Therapy in the Perioperative and Critical Care Setting

26 May, 2020 | 09:28h | UTC

Intravenous fluid therapy in the perioperative and critical care setting: Executive summary of the International Fluid Academy (IFA) – Annals of Intensive Care

 


[Abstract Only] Meta-Analysis: Helicobacter Pylori Eradication Therapy to Prevent Gastric Cancer

26 May, 2020 | 09:21h | UTC

Helicobacter pylori eradication therapy to prevent gastric cancer: systematic review and meta-analysis – Gut (abstract only – $ for full-text)

 


Systematic Review Shows Evidence is Inconclusive on the Use of Non‐nutritive Sweeteners for Diabetes Mellitus

26 May, 2020 | 09:27h | UTC

Non‐nutritive sweeteners for diabetes mellitus – Cochrane Library

Summary: Non-nutritive sweeteners for diabetes mellitus – Cochrane Library

 


Chest Trauma: Current Recommendations for Rib Fractures, Pneumothorax, and Other Injuries

26 May, 2020 | 09:18h | UTC

Chest Trauma: Current Recommendations for Rib Fractures, Pneumothorax, and Other Injuries – Current Anesthesiology Reports

 


Remdesivir for the Treatment of Covid-19 — Preliminary Report

25 May, 2020 | 02:06h | UTC

Remdesivir for the Treatment of Covid-19 — Preliminary Report – New England Journal of Medicine

Commentaries: Preliminary report on NIAID trial of remdesivir – PulmCrit AND Peer-reviewed data shows remdesivir for COVID-19 improves time to recovery – National Institutes of Health AND Covid-19 study details benefits of treatment with remdesivir, and also its limitations – STAT

 

Related Commentary on Twitter (Thread – Click for more)

 


Perspective: The World May Be Overestimating the Power of Vaccines

25 May, 2020 | 01:55h | UTC

The world needs Covid-19 vaccines. It may also be overestimating their power – STAT

 


Hydroxychloroquine and Chloroquine for Covid-19: Large Observational Analysis Finds No Benefit and Possible Harm

25 May, 2020 | 02:03h | UTC

Hydroxychloroquine or chloroquine with or without a macrolide for treatment of COVID-19: a multinational registry analysis – The Lancet

Commentaries: Chloroquine or hydroxychloroquine for COVID-19: why might they be hazardous? – The Lancet AND What a big new study on malaria drugs as Covid-19 treatments tells us — and what it doesn’t – STAT AND Hydroxychloroquine May Cause More Harm Than Benefit To COVID-19 Patients, Says New Lancet Study – Health Policy Watch

 


Opinion: Why Countries Should Stop Using Anti-malarial Drugs for COVID-19

25 May, 2020 | 02:02h | UTC

Why countries should stop using anti-malarial drugs for COVID-19 – The Conversation

 


[Preprint] Meta-Analysis: Susceptibility to and Transmission of COVID-19 Amongst Children and Adolescents Compared with Adults

25 May, 2020 | 01:52h | UTC

Susceptibility to and transmission of COVID-19 amongst children and adolescents compared with adults: a systematic review and meta-analysis – medRxiv

Commentaries: Children appear half as likely to catch COVID-19 as adults – London School of Hygiene & Tropical Medicine AND Expert reaction to systematic review preprint looking at susceptibility to SARS-CoV-2 infection in children and adolescents compared with adults – Science Media Centre

 


Editorial – SARS-CoV2 Vaccines: Slow is Fast

25 May, 2020 | 01:54h | UTC

SARS-CoV2 vaccines: Slow is fast – Science

 


Promising Early Results with New Vaccine from China in Phase I Trial

25 May, 2020 | 01:57h | UTC

Safety, tolerability, and immunogenicity of a recombinant adenovirus type-5 vectored COVID-19 vaccine: a dose-escalation, open-label, non-randomised, first-in-human trial – The Lancet

Commentaries: First human trial of COVID-19 vaccine finds it is safe and induces rapid immune response – The Lancet AND Early Study Of Covid-19 Vaccine Developed In China Sees Mixed Results – Forbes AND Coronavirus Vaccine Shows Promising Early Results in China – The New York Times AND A Chinese biotech just published the first human data for its coronavirus vaccine candidate, supporting further trials – Business Insider AND Experts skeptical after researchers report positive vaccine results – CNN AND Two COVID-19 Vaccine Candidates Induce Immune Response In Healthy Volunteers – Health Policy Watch

 


SARS-CoV-2 RNA in Wastewater Anticipated COVID-19 Occurrence in a Low Prevalence Area

25 May, 2020 | 01:47h | UTC

SARS-CoV-2 RNA in wastewater anticipated COVID-19 occurrence in a low prevalence area – Water Research

Related: New Research Examines Wastewater to Detect Community Spread of Covid-19

 


Study: 10 of 60 Patients Treated for COVID-19 Persisted with Positive RT-PCR Results from 4 to 24 Days After Hospital Discharge

25 May, 2020 | 01:50h | UTC

Coronavirus Disease 2019 Test Results After Clinical Recovery and Hospital Discharge Among Patients in China – JAMA Network Open

Commentaries: Expert reaction to study on PCR testing results from 60 people after clinical recovery from COVID-19 – Science Media Centre AND 16% of recovered patients test positive for COVID-19 weeks after discharge: study – UPI

 


Systematic Review: Ventilation Techniques and Risk for Transmission of Coronavirus Disease, Including COVID-19

25 May, 2020 | 01:40h | UTC

Ventilation Techniques and Risk for Transmission of Coronavirus Disease, Including COVID-19: A Living Systematic Review of Multiple Streams of Evidence – Annals of Internal Medicine

 


Meta-Analysis: Corticosteroids May Reduce Mortality for Patients with COVID-19 and ARDS

25 May, 2020 | 01:45h | UTC

Efficacy and safety of corticosteroids in COVID-19 based on evidence for COVID-19, other coronavirus infections, influenza, community-acquired pneumonia and acute respiratory distress syndrome: a systematic review and meta-analysis – Canadian Medical Association Journal

Related: Early Short Course Corticosteroids in Hospitalized Patients with COVID-19 – Clinical Infectious Diseases

 


Clinical Guidance: Thromboembolism and Anticoagulant Therapy During the COVID-19 Pandemic

25 May, 2020 | 01:43h | UTC

Thromboembolism and anticoagulant therapy during the COVID-19 pandemic: interim clinical guidance from the anticoagulation forum – Journal of Thrombosis and Thrombolysis

Related: Coagulation abnormalities and thrombosis in patients with COVID-19 – The Lancet AND COVID-19 and its implications for thrombosis and anticoagulation – Blood AND Prevention and Treatment of Venous Thromboembolism Associated with Coronavirus Disease 2019 Infection: A Consensus Statement before Guidelines – Thrombosis and Haemostasis AND Thrombosis and COVID-19: FAQs For Current Practice – American College of Cardiology

 


Cloth Masks May Prevent Transmission of COVID-19: An Evidence-Based, Risk-Based Approach

25 May, 2020 | 01:42h | UTC

Cloth Masks May Prevent Transmission of COVID-19: An Evidence-Based, Risk-Based Approach – Annals of Internal Medicine

 


WHO: At Least 80 million Children Under One at Risk of Diseases Such as Diphtheria, Measles and Polio as COVID-19 Disrupts Routine Vaccination Efforts

25 May, 2020 | 01:34h | UTC

At least 80 million children under one at risk of diseases such as diphtheria, measles and polio as COVID-19 disrupts routine vaccination efforts, warn Gavi, WHO and UNICEF – World Health Organization

Commentaries: WHO warns millions of children at risk as Covid-19 pandemic disrupts routine vaccinations – STAT AND Polio and Measles Could Surge After Disruption of Vaccine Programs – The New York Times

Related: Indirect Effects of the COVID-19 Pandemic on Maternal and Child Mortality in Low-income and Middle-income Countries

 


Updated CDC School Reopening Guidelines

25 May, 2020 | 01:38h | UTC

CDC School Reopening Guidelines – Centers for Disease Control and Prevention

Commentaries: Everyone Needs To Stop Freaking Out About CDC School Reopening Guidelines – Forbes AND What the CDC guidelines for reopening schools recommend, including mask wearing and closing playgrounds – Business Insider

 


CDC: The Coronavirus ‘Does Not Spread Easily’ From Contaminated Surfaces

25 May, 2020 | 01:39h | UTC

CDC: The coronavirus ‘does not spread easily’ from contaminated surfaces – Business Insider

See also: 6 feet away isn’t enough. Covid-19 risk involves other dimensions, too. – Vox AND Coronavirus Does Not Spread Easily on Surfaces, C.D.C. Says – The New York Times AND CDC Advice On Surface Spread Of COVID-19 ‘Has Not Changed,’ Agency Says – NPR

 


[Abstract Only] Randomized Trial: Haloperidol Effective for the Treatment of Headache in the Emergency Department

25 May, 2020 | 01:33h | UTC

Treatment of Headache in the Emergency Department: Haloperidol in the Acute Setting (THE-HA Study): A Randomized Clinical Trial – The Journal of Emergency Medicine

 


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