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UK becomes first country to authorize Pfizer/BioNTech’s Covid-19 vaccine, first shots roll out next week

3 Dec, 2020 | 08:44h | UTC

UK becomes first country to authorize Pfizer/BioNTech’s Covid-19 vaccine, first shots roll out next week – CNN

Press release: UK medicines regulator gives approval for first UK COVID-19 vaccine – Medicines and Healthcare products Regulatory Agency

See also: Covid-19: Pfizer/BioNTech vaccine judged safe for use in UK – BBC AND Expert reaction to news that the MHRA has approved the Pfizer/BioNTech COVID-19 vaccine for mass UK roll out – Science Media Centre AND UK approves Pfizer/BioNTech Covid vaccine for rollout next week – The Guardian

 


WHO Solidarity Trial: Remdesivir, hydroxychloroquine, lopinavir, and interferon regimens had little or no effect on hospitalized patients with Covid-19

3 Dec, 2020 | 08:47h | UTC

Repurposed Antiviral Drugs for Covid-19 — Interim WHO Solidarity Trial Results – New England Journal of Medicine

Audio Interview: Caring for Hospitalized Patients with Covid-19

 

Commentary on Twitter (thread – click for more)

 


Review: Cytokine Storm

3 Dec, 2020 | 08:46h | UTC

Cytokine Storm – New England Journal of Medicine

 

Commentary on Twitter

 


Randomized trial: In treatment naive early rheumatoid arthritis, a treatment based on methotrexate and low dose corticosteroids was safe and effective and non-inferior to certolizumab and tocilizumab, but not to abatacept

3 Dec, 2020 | 08:35h | UTC

Active conventional treatment and three different biological treatments in early rheumatoid arthritis: phase IV investigator initiated, randomised, observer blinded clinical trial – The BMJ

 


CDC to shorten COVID-19 quarantine to 10 days, 7 with test

3 Dec, 2020 | 08:40h | UTC

CDC to shorten COVID-19 quarantine to 10 days, 7 with test – Associated Press

Commentary: CDC Shortens Its COVID-19 Quarantine Recommendations – NPR

 


Special Report: The Covid-19 vaccines are a marvel of science. Here’s how we can make the best use of them

3 Dec, 2020 | 08:42h | UTC

The Covid-19 vaccines are a marvel of science. Here’s how we can make the best use of them – STAT

 


Meta-analysis: Oxytocin used as first‐line treatment of postpartum hemorrhage probably is more effective than misoprostol with less side‐effects. The evidence for most other uterotonic agents is limited.

3 Dec, 2020 | 08:31h | UTC

Uterotonic agents for first‐line treatment of postpartum haemorrhage: a network meta‐analysis – Cochrane Library

Summary: Which drug is best for treating excessive bleeding after childbirth? – Cochrane Library

 


Randomized trial: In areas with intense malaria transmission, postdischarge malaria chemoprevention in children recently treated for severe anemia prevented deaths and readmissions

3 Dec, 2020 | 08:33h | UTC

Malaria Chemoprevention in the Postdischarge Management of Severe Anemia – New England Journal of Medicine

Visual abstract: Malaria Chemoprevention for Management of Severe Anemia

 


Guideline for the perioperative management of hip fractures 2020

3 Dec, 2020 | 08:30h | UTC

Guideline for the management of hip fractures 2020 – Anaesthesia

 

Commentary on Twitter

 


Review: Perioperative venous thromboembolism prophylaxis

3 Dec, 2020 | 08:28h | UTC

Perioperative Venous Thromboembolism Prophylaxis – Mayo Clinic Proceedings

 


Case series: Shedding of viable SARS-CoV-2 after immunosuppressive therapy for cancer

2 Dec, 2020 | 07:31h | UTC

Shedding of Viable SARS-CoV-2 after Immunosuppressive Therapy for Cancer – New England Journal of Medicine

 


What’s the difference between viral shedding and reinfection with COVID-19?

2 Dec, 2020 | 07:29h | UTC

What’s the difference between viral shedding and reinfection with COVID-19? – The Conversation

 


Opinion: “Put an end to publication by proclamation for Covid vaccines”

2 Dec, 2020 | 07:27h | UTC

Put An End To Publication By Proclamation For Covid Vaccines – Forbes

 


One in five covid-19 patients are diagnosed with a mental illness within three months

2 Dec, 2020 | 07:24h | UTC

One in five covid-19 patients are diagnosed with a mental illness within three months – MIT Technology Review

Original study: Bidirectional associations between COVID-19 and psychiatric disorder: retrospective cohort studies of 62 354 COVID-19 cases in the USA – The Lancet Psychiatry

 

Commentary on Twitter

https://twitter.com/TheLancetPsych/status/1326158490423996417

 


CDC panel moves health workers, nursing home residents to front of COVID vaccine line

2 Dec, 2020 | 07:26h | UTC

CDC panel moves health workers, nursing home residents to front of COVID vaccine line – CIDRAP

See also: Health workers, long-term care facilities should get Covid-19 vaccine first, CDC advisory panel says – STAT

 


Two meta-analysis find ethnic minorities disproportionately affected by coronavirus

2 Dec, 2020 | 07:22h | UTC

Meta-analysis 1: Racial and Ethnic Disparities in COVID-19–Related Infections, Hospitalizations, and Deaths: A Systematic Review – Annals of Internal Medicine

Meta-analysis 2: Ethnicity and clinical outcomes in COVID-19: A systematic review and meta-analysis – EClinicalMedicine

Commentary: Ethnic minorities disproportionately affected by coronavirus, meta-study finds – Reuters

 


Global estimates of the need for rehabilitation based on the Global Burden of Disease study 2019. At least one in every three people in the world needs rehabilitation at some point in the course of their illness or injury

2 Dec, 2020 | 07:17h | UTC

Global estimates of the need for rehabilitation based on the Global Burden of Disease study 2019: a systematic analysis for the Global Burden of Disease Study 2019 – The Lancet

Commentary: The Lancet: One in three people worldwide could benefit from rehabilitation at least once in the course of their illness or injury, first global study estimates – Institute for Health Metrics and Evaluation

 


Systematic review: Outdoor transmission of SARS-CoV-2 and other respiratory viruses. “The odds of indoor transmission was very high compared to outdoors (18.7 times)”

2 Dec, 2020 | 07:19h | UTC

Outdoor Transmission of SARS-CoV-2 and Other Respiratory Viruses, a Systematic Review – The Journal of Infectious Diseases

 

Commentary on Twitter

 


IDSA 2020 Guidelines for the prevention, diagnosis and treatment of Lyme disease

1 Dec, 2020 | 08:28h | UTC

Clinical Practice Guidelines by the Infectious Diseases Society of America (IDSA), American Academy of Neurology (AAN), and American College of Rheumatology (ACR): 2020 Guidelines for the Prevention, Diagnosis and Treatment of Lyme Disease – Clinical Infectious Diseases

Commentary: IDSA, AAN, and ACR Release Guidelines for Prevention, Diagnosis, and Treatment of Lyme Disease – Infectious Diseases Society of America

 


Randomized trial: A low-fat vegan diet can reduce body weight and improve insulin sensitivity in overweight adults

2 Dec, 2020 | 07:16h | UTC

Effect of a Low-Fat Vegan Diet on Body Weight, Insulin Sensitivity, Postprandial Metabolism, and Intramyocellular and Hepatocellular Lipid Levels in Overweight Adults: A Randomized Clinical Trial – JAMA Network Open

Commentary: Plant-based diet ramps up metabolism, according to new study – Physicians Committee for Responsible Medicine

 


WHO World malaria report 2020: 20 years of global progress & challenges

1 Dec, 2020 | 08:27h | UTC

World malaria report 2020: 20 years of global progress & challenges – World Health Organization

News Release: WHO calls for reinvigorated action to fight malaria

 


Review: Hearing loss in children

2 Dec, 2020 | 07:14h | UTC

Hearing Loss in Children: A Review – JAMA (free for a limited period)

Author interview: Hearing Loss in Children

 


Cohort study: Higher dose Z-drug use in dementia is associated with increased fracture and stroke risks, similar or greater to that for higher dose benzodiazepines

1 Dec, 2020 | 08:25h | UTC

Adverse effects of Z-drugs for sleep disturbance in people living with dementia: a population-based cohort study – BMC Medicine

Commentary: The danger of Z-drugs for dementia patients – University of Exeter

 


NICE COVID-19 guideline: Prevention of thromboembolism in patients with COVID-19. “For patients who are having advanced respiratory support: consider increasing pharmacological VTE prophylaxis to an intermediate dose”

1 Dec, 2020 | 08:19h | UTC

COVID-19 rapid guideline: reducing the risk of venous thromboembolism in over 16s with COVID-19 – National Institute for Health and Care Excellence

 


Moderna released more Covid-19 vaccine results. They’re very encouraging.

1 Dec, 2020 | 08:15h | UTC

Moderna released more Covid-19 vaccine results. They’re very encouraging. – Vox

News release: Moderna Announces Primary Efficacy Analysis in Phase 3 COVE Study for Its COVID-19 Vaccine Candidate and Filing Today with U.S. FDA for Emergency Use Authorization

Commentaries: ‘Absolutely remarkable’: No one who got Moderna’s vaccine in trial developed severe COVID-19 – Science AND Moderna to submit Covid-19 vaccine to FDA as full results show 94% efficacy – STAT AND More Good News For Moderna’s COVID-19 Vaccine Candidate – NPR AND Moderna to seek emergency authorization for COVID-19 vaccine – CIDRAP

 

Commentary on Twitter

 


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