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UK becomes first country to authorize Pfizer/BioNTech’s Covid-19 vaccine, first shots roll out next week
3 Dec, 2020 | 08:44h | UTCPress release: UK medicines regulator gives approval for first UK COVID-19 vaccine – Medicines and Healthcare products Regulatory Agency
See also: Covid-19: Pfizer/BioNTech vaccine judged safe for use in UK – BBC AND Expert reaction to news that the MHRA has approved the Pfizer/BioNTech COVID-19 vaccine for mass UK roll out – Science Media Centre AND UK approves Pfizer/BioNTech Covid vaccine for rollout next week – The Guardian
WHO Solidarity Trial: Remdesivir, hydroxychloroquine, lopinavir, and interferon regimens had little or no effect on hospitalized patients with Covid-19
3 Dec, 2020 | 08:47h | UTCAudio Interview: Caring for Hospitalized Patients with Covid-19
Commentary on Twitter (thread – click for more)
The biggest multinational pandemic randomised trial #SOLIDARITYtrial published in the New England Journal of Medicine. https://t.co/VbpbpziFwm
WHO, trial leaders, numerous countries, hospitals, doctors, nurses, patients & many others are to be congratulated!
Key results 👇🏾 1/5 pic.twitter.com/Xe9K6EfUpc
— Kari Tikkinen (@KariTikkinen) December 2, 2020
Review: Cytokine Storm
3 Dec, 2020 | 08:46h | UTCCytokine Storm – New England Journal of Medicine
Commentary on Twitter
Cytokine storm is a prominent feature in severe #COVID19. This new @NEJM review on it is as good as it gets. By @DavidFajgenbaum @carlhjune @PennMedicine https://t.co/a4qE7xGR58 pic.twitter.com/Ul1HrnL8Ve
— Eric Topol (@EricTopol) December 2, 2020
Randomized trial: In treatment naive early rheumatoid arthritis, a treatment based on methotrexate and low dose corticosteroids was safe and effective and non-inferior to certolizumab and tocilizumab, but not to abatacept
3 Dec, 2020 | 08:35h | UTC
CDC to shorten COVID-19 quarantine to 10 days, 7 with test
3 Dec, 2020 | 08:40h | UTCCDC to shorten COVID-19 quarantine to 10 days, 7 with test – Associated Press
Commentary: CDC Shortens Its COVID-19 Quarantine Recommendations – NPR
Special Report: The Covid-19 vaccines are a marvel of science. Here’s how we can make the best use of them
3 Dec, 2020 | 08:42h | UTCThe Covid-19 vaccines are a marvel of science. Here’s how we can make the best use of them – STAT
Meta-analysis: Oxytocin used as first‐line treatment of postpartum hemorrhage probably is more effective than misoprostol with less side‐effects. The evidence for most other uterotonic agents is limited.
3 Dec, 2020 | 08:31h | UTCSummary: Which drug is best for treating excessive bleeding after childbirth? – Cochrane Library
Randomized trial: In areas with intense malaria transmission, postdischarge malaria chemoprevention in children recently treated for severe anemia prevented deaths and readmissions
3 Dec, 2020 | 08:33h | UTCVisual abstract: Malaria Chemoprevention for Management of Severe Anemia
Guideline for the perioperative management of hip fractures 2020
3 Dec, 2020 | 08:30h | UTCGuideline for the management of hip fractures 2020 – Anaesthesia
Commentary on Twitter
🔐This new @Assoc_Anaes guideline for the management of hip fractures from @IainMoppett and colleagues contains more specific recommendations about controversial areas of patient management than were made in 2011.
Available now and #FOAMed forever!
🔗https://t.co/B5cdxSx2mU pic.twitter.com/8nQiUNpdS2
— 𝘈𝘯𝘢𝘦𝘴𝘵𝘩𝘦𝘴𝘪𝘢 (@Anaes_Journal) December 2, 2020
Review: Perioperative venous thromboembolism prophylaxis
3 Dec, 2020 | 08:28h | UTCPerioperative Venous Thromboembolism Prophylaxis – Mayo Clinic Proceedings
Case series: Shedding of viable SARS-CoV-2 after immunosuppressive therapy for cancer
2 Dec, 2020 | 07:31h | UTC
What’s the difference between viral shedding and reinfection with COVID-19?
2 Dec, 2020 | 07:29h | UTCWhat’s the difference between viral shedding and reinfection with COVID-19? – The Conversation
Opinion: “Put an end to publication by proclamation for Covid vaccines”
2 Dec, 2020 | 07:27h | UTCPut An End To Publication By Proclamation For Covid Vaccines – Forbes
One in five covid-19 patients are diagnosed with a mental illness within three months
2 Dec, 2020 | 07:24h | UTC
Commentary on Twitter
https://twitter.com/TheLancetPsych/status/1326158490423996417
CDC panel moves health workers, nursing home residents to front of COVID vaccine line
2 Dec, 2020 | 07:26h | UTCCDC panel moves health workers, nursing home residents to front of COVID vaccine line – CIDRAP
Two meta-analysis find ethnic minorities disproportionately affected by coronavirus
2 Dec, 2020 | 07:22h | UTCMeta-analysis 1: Racial and Ethnic Disparities in COVID-19–Related Infections, Hospitalizations, and Deaths: A Systematic Review – Annals of Internal Medicine
Meta-analysis 2: Ethnicity and clinical outcomes in COVID-19: A systematic review and meta-analysis – EClinicalMedicine
Commentary: Ethnic minorities disproportionately affected by coronavirus, meta-study finds – Reuters
Global estimates of the need for rehabilitation based on the Global Burden of Disease study 2019. At least one in every three people in the world needs rehabilitation at some point in the course of their illness or injury
2 Dec, 2020 | 07:17h | UTC
Systematic review: Outdoor transmission of SARS-CoV-2 and other respiratory viruses. “The odds of indoor transmission was very high compared to outdoors (18.7 times)”
2 Dec, 2020 | 07:19h | UTC
Commentary on Twitter
Outdoor Transmission of SARS-CoV-2 and Other Respiratory Viruses, a Systematic Review https://t.co/lmWQNgpIfd Existing evidence supports the wide-held belief that the the risk of #SARSCoV2 transmission is lower outdoors (< 10%).
— Carlos del Rio (@CarlosdelRio7) December 1, 2020
IDSA 2020 Guidelines for the prevention, diagnosis and treatment of Lyme disease
1 Dec, 2020 | 08:28h | UTC
Randomized trial: A low-fat vegan diet can reduce body weight and improve insulin sensitivity in overweight adults
2 Dec, 2020 | 07:16h | UTCCommentary: Plant-based diet ramps up metabolism, according to new study – Physicians Committee for Responsible Medicine
WHO World malaria report 2020: 20 years of global progress & challenges
1 Dec, 2020 | 08:27h | UTCWorld malaria report 2020: 20 years of global progress & challenges – World Health Organization
News Release: WHO calls for reinvigorated action to fight malaria
Review: Hearing loss in children
2 Dec, 2020 | 07:14h | UTCHearing Loss in Children: A Review – JAMA (free for a limited period)
Author interview: Hearing Loss in Children
Cohort study: Higher dose Z-drug use in dementia is associated with increased fracture and stroke risks, similar or greater to that for higher dose benzodiazepines
1 Dec, 2020 | 08:25h | UTCCommentary: The danger of Z-drugs for dementia patients – University of Exeter
NICE COVID-19 guideline: Prevention of thromboembolism in patients with COVID-19. “For patients who are having advanced respiratory support: consider increasing pharmacological VTE prophylaxis to an intermediate dose”
1 Dec, 2020 | 08:19h | UTC
Moderna released more Covid-19 vaccine results. They’re very encouraging.
1 Dec, 2020 | 08:15h | UTCModerna released more Covid-19 vaccine results. They’re very encouraging. – Vox
Commentaries: ‘Absolutely remarkable’: No one who got Moderna’s vaccine in trial developed severe COVID-19 – Science AND Moderna to submit Covid-19 vaccine to FDA as full results show 94% efficacy – STAT AND More Good News For Moderna’s COVID-19 Vaccine Candidate – NPR AND Moderna to seek emergency authorization for COVID-19 vaccine – CIDRAP
Commentary on Twitter
Moderna has announced the final results of the 30,000-person efficacy trial for its #COVID19 vaccine candidate, reporting that the vaccine had 100% efficacy against severe disease. https://t.co/Cgg0I5nv9r
— News from Science (@NewsfromScience) November 30, 2020


