All Posts
Consensus statement: Diagnosis, treatment, and follow-up of heart failure patients by general practitioners
17 Jan, 2021 | 21:48h | UTC
Review: Gastroesophageal reflux disease
17 Jan, 2021 | 21:52h | UTCGastroesophageal Reflux Disease: A Review – JAMA (free for a limited period)
Randomized trial: Inhaled Treprostinil in pulmonary hypertension due to interstitial lung disease
17 Jan, 2021 | 21:47h | UTCCommentaries: Inhaled Treprostinil Beneficial in Pulmonary Hypertension – HealthDay
Commentary on Twitter
Patients with pulmonary hypertension due to interstitial lung disease were randomly assigned to inhale treprostinil or placebo. At 16 weeks, there was a significant improvement in exercise capacity with inhaled treprostinil as compared with placebo, assessed by a 6-minute walk.
— NEJM (@NEJM) January 14, 2021
Long-term safety of fecal microbiota transplantation for recurrent Clostridioides difficile infection
17 Jan, 2021 | 21:50h | UTCLong-term Safety of Fecal Microbiota Transplantation for Recurrent Clostridioides difficile Infection – Gastroenterology (link to abstract – $ for full-text)
Commentary: Fecal Transplants Safe Long Term for Recurrent C. Diff — But new-onset conditions post-fecal microbiota transplantation need further study – MedPage Today (free registration required)
Systematic review: Insufficient evidence to recommend Trypanocidal drugs for late-stage, symptomatic Chagas disease
17 Jan, 2021 | 21:44h | UTCSummary: Trypanocidal drugs for late-stage, symptomatic Chagas disease – Cochrane Library
Meta-analysis: Safety and efficacy of dexmedetomidine in acutely ill adults requiring non-invasive ventilation
17 Jan, 2021 | 21:42h | UTCSafety and efficacy of dexmedetomidine in acutely ill adults requiring non-invasive ventilation: a systematic review and meta-analysis of randomized trials – CHEST (link to abstract – $ for full-text)
Review: Anesthetic management of conduction disturbances following transcatheter aortic valve replacement
17 Jan, 2021 | 21:39h | UTC
Commentary on Twitter
Conduction disturbances remain common following transcatheter aortic valve replacement (#TAVR). Anesthetic Management of Conduction Disturbances following Transcatheter Aortic Valve Replacement: A Review of the 2020 ACC Expert Consensus Decision Pathway. https://t.co/s7e2MEJFAI pic.twitter.com/VqUcdUEehp
— Journal of Cardiothoracic and Vascular Anesthesia (@JCVAonline) December 26, 2020
Meta-analysis: Effect of ultra-short-acting β-blockers on mortality in patients with persistent tachycardia despite initial resuscitation
17 Jan, 2021 | 21:41h | UTCEffect of ultra-short-acting β-blockers on mortality in patients with persistent tachycardia despite initial resuscitation: a systematic review and meta-analysis of randomized controlled trials – CHEST (link to abstract – $ for full-text)
Observational study: Among patients hospitalized with Covid-19 not receiving mechanical ventilation, transfusion of plasma with higher anti–SARS-CoV-2 IgG antibody levels is linked to lower risk of death than transfusion of plasma with lower antibody levels
15 Jan, 2021 | 08:59h | UTCEditorial: (A Little) Clarity on Convalescent Plasma for Covid-19 – New England Journal of Medicine
Commentaries: Expert reaction to study looking at convalescent plasma antibody levels and risk of death from COVID-19 – Science Media Centre AND Antibody-rich convalescent plasma may lower risk of COVID death – CIDRAP
Opinion: RCTs don’t justify using convalescent plasma or antibody cocktails
15 Jan, 2021 | 08:58h | UTCRCTs don’t justify using convalescent plasma or antibody cocktails – PulmCrit
[Preprint] Past COVID-19 infection provides some immunity but people may still carry and transmit virus
15 Jan, 2021 | 09:02h | UTCSee also: Covid-19: Past infection provides 83% protection for five months but may not stop transmission, study finds – The BMJ AND COVID reinfections are unusual — but could still help the virus to spread – Nature AND COVID-19 infection gives some immunity, but virus can still be spread, study finds – Reuters AND Expert reaction to a preprint from the SIREN study looking at SARS-CoV-2 infection rates in antibody positive healthcare workers – Science Media Centre
Nutrition in cancer care: A brief, practical guide with a focus on clinical practice
17 Jan, 2021 | 21:37h | UTC
Perspective: Ivermectin for COVID-19 — Breakthrough Treatment or Hydroxychloroquine Redux?
15 Jan, 2021 | 08:51h | UTCRelated video: Ivermectin For COVID-19 | A Doctor Explains – ZDoggMD
NIH Guideline Statement: “there are insufficient data to recommend either for or against the use of ivermectin for the treatment of COVID-19”
15 Jan, 2021 | 08:53h | UTC
Covid-19 Vaccine — Frequently Asked Questions
15 Jan, 2021 | 08:49h | UTCCovid-19 Vaccine — Frequently Asked Questions – New England Journal of Medicine
Progression of myopia in school-aged children after COVID-19 home confinement
15 Jan, 2021 | 08:55h | UTCProgression of Myopia in School-Aged Children After COVID-19 Home Confinement – JAMA Ophthalmology
Commentaries: 2020 as the Year of Quarantine Myopia – JAMA Ophthalmology AND How Does Home Confinement Impact Children’s Eyesight? – AJMC AND COVID-19: Home Quarantine Linked to Increase in Myopia Among Younger Children – NEJM Journal Watch AND Vision problems arise in young school kids in COVID-19 quarantine – CIDRAP
Interview: 2020 as the Year of Quarantine Myopia
COVID-19 measures also suppress flu—for now
15 Jan, 2021 | 08:46h | UTCCOVID-19 measures also suppress flu—for now – Science
Meta-analysis of randomized trials: patients adhering to a low carbohydrate diet for six months may experience remission of diabetes without adverse consequences
15 Jan, 2021 | 08:43h | UTCCommentary: Short term low carbohydrate diet linked to remission of type 2 diabetes – The BMJ
Short term low carbohydrate diet linked to remission of type 2 diabetes in new #BMJResearch. But further trials are needed to determine longer term effects, say researchers @methodsnerd et al.
Includes a #VisualAbstract by @will_s_t #BMJInfographichttps://t.co/qihKAib11U pic.twitter.com/3rPH0ZrSGL— The BMJ (@bmj_latest) January 14, 2021
Covid-19: When to start invasive ventilation is “the million dollar question”
15 Jan, 2021 | 08:48h | UTCCovid-19: When to start invasive ventilation is “the million dollar question” – The BMJ
Commentary on Twitter
Options for ventilating covid-19 patients have expanded since the first wave of the pandemic, but doctors are unsure of the best management pathway because evidence is lacking, reports @ingridtorjesenhttps://t.co/iKldASmahF
— The BMJ (@bmj_latest) January 14, 2021
Randomized trial: Naltrexone-Bupropion combination may help some people (13.6% vs. 2.5% with placebo) with methamphetamine use disorder
15 Jan, 2021 | 08:39h | UTCBupropion and Naltrexone in Methamphetamine Use Disorder – New England Journal of Medicine (link to abstract – $ for full-text)
Commentaries: Combination of two drugs can help treat methamphetamine addiction for some, new clinical trial data shows – STAT AND Naltrexone-Bupropion Combination May Help People With Methamphetamine Use Disorder – Psychiatric News Alert
Covid-19 deaths are the highest they’ve ever been — and the more infectious variants could make things much worse
15 Jan, 2021 | 08:45h | UTC
Meta-analysis of randomized trials: SGLT-2 inhibitors and GLP-1 receptor agonists reduce cardiovascular and renal outcomes in type 2 diabetes
15 Jan, 2021 | 08:41h | UTCCalculator based on the results: interactive decision support tool for outcomes
Cohort study: Even small amounts of alcohol consumption linked to increased risk of atrial fibrillation
15 Jan, 2021 | 08:40h | UTCEditorial: Alcohol consumption, atrial fibrillation, and cardiovascular disease: finding the right balance
A new mandate highlights costs, benefits of making all scientific articles free to read
15 Jan, 2021 | 08:30h | UTCA new mandate highlights costs, benefits of making all scientific articles free to read – Science
Related: Open-access Science Funders Announce Price Transparency Rules for Publishers (several resources on the subject)
Dietary Guidelines for Americans, 2020-2025
15 Jan, 2021 | 08:31h | UTCDietary Guidelines for Americans, 2020-2025 – United States Department of Agriculture
Commentary: U.S. Diet Guidelines Sidestep Scientific Advice to Cut Sugar and Alcohol – The New York Times