All Posts
SARS-CoV-2 vaccines: Much accomplished, much to learn
20 Jan, 2021 | 01:51h | UTCSARS-CoV-2 Vaccines: Much Accomplished, Much to Learn – Annals of Internal Medicine
Commentary on Twitter
New, from Dr. Fauci & colleagues
SARS-CoV-2 Vaccines: Much Accomplished, Much to Learn https://t.co/yguZOquGJF pic.twitter.com/OIBouGS6dr
— Ilan Schwartz is on🦋 (@GermHunterMD) January 18, 2021
What we now know — and don’t know — about the coronavirus variants
20 Jan, 2021 | 01:41h | UTCWhat we now know — and don’t know — about the coronavirus variants – STAT
Related: Covid-19: What new variants are emerging and how are they being investigated? – The BMJ
Perspective: Covid-19 vaccine guidance for those who are lactating is based on faulty assumptions, experts say
20 Jan, 2021 | 01:40h | UTC
Randomized trial: Endovascular treatment alone noninferior to intravenous alteplase plus endovascular treatment on functional independence in patients with acute ischemic stroke
20 Jan, 2021 | 01:35h | UTCEffect of Endovascular Treatment Alone vs Intravenous Alteplase Plus Endovascular Treatment on Functional Independence in Patients With Acute Ischemic Stroke: The DEVT Randomized Clinical Trial – JAMA (free for a limited period)
Related study: Effect of Mechanical Thrombectomy Without vs With Intravenous Thrombolysis on Functional Outcome Among Patients With Acute Ischemic Stroke: The SKIP Randomized Clinical Trial – JAMA (free for a limited period)
Editorial: Intravenous Thrombolysis Before Endovascular Thrombectomy for Acute Ischemic Stroke – JAMA (free for a limited period)
Video: Thrombolysis Before Thrombectomy for Stroke
Systematic review on prophylaxis for COVID-19: Hydroxychloroquine does not work, little evidence regarding other drugs
20 Jan, 2021 | 01:38h | UTCProphylaxis for COVID-19: a systematic review – Clinical Microbiology and Infection
USPSTF Statement: Interventions for tobacco smoking cessation in adults
20 Jan, 2021 | 01:32h | UTCEditorial: A Comprehensive Approach to Increase Adult Tobacco Cessation – JAMA
Author Interview: USPSTF Recommendation: Tobacco Cessation in Adults
JAMA Patient Page: Interventions to Promote Tobacco Cessation
Perspective – Sugar-sweetened beverage taxes: Lessons to date and the future of taxation
20 Jan, 2021 | 01:28h | UTCSugar-sweetened beverage taxes: Lessons to date and the future of taxation – PLOS Medicine
Related: Meta-Analysis: Impact of Sugar‐sweetened Beverage Taxes on Purchases and Dietary Intake (free study and resources on the subject)
Guideline synopsis: Initiating Pharmacologic Treatment in Tobacco-Dependent Adults
20 Jan, 2021 | 01:31h | UTCInitiating Pharmacologic Treatment in Tobacco-Dependent Adults – JAMA (free for a limited period)
Author Interview: Pharmacologic Management of Tobacco Cessation
An epidemic of overdiagnosis: Melanoma diagnoses sky rocket
20 Jan, 2021 | 01:30h | UTCAn epidemic of overdiagnosis: Melanoma diagnoses sky rocket – Brigham and Women’s Hospital AND Does Screening for Skin Cancer Result in Melanoma Overdiagnosis? – Univadis
Original study: The Rapid Rise in Cutaneous Melanoma Diagnoses ($)
Related: Overdiagnosis: what it is and what it isn’t – BMJ Evidence Based Medicine (free) AND Overdiagnosis across medical disciplines: a scoping review – The BMJ Open (free) AND Too much medical care: bad for you, bad for health care systems – STAT News (free) AND Screening: How overdiagnosis and other harms can undermine the benefits – Health News Review (free) AND Overdiagnosis: causes and consequences in primary health care – Canadian Family Physician (free) AND Five warning signs of overdiagnosis – The Conversation (free) AND What is overdiagnosed cancer? And why does it matter? – Croakey (free) AND Blame rising cancer overdiagnosis on ‘irrational exuberance’ for early detection – STAT (free) AND Preventing overdiagnosis and the harms of too much sport and exercise medicine – British Journal of Sports Medicine (free)
Meta-analysis: Early initiation of renal replacement therapy is not associated with survival benefit in critically ill patients with acute kidney injury
20 Jan, 2021 | 01:25h | UTC
Meta-analysis: Inconclusive evidence regarding a benefit of systematic early mobilization in mechanically ventilated adult ICU patients
20 Jan, 2021 | 01:24h | UTC
Science family of journals announces change to open-access policy
20 Jan, 2021 | 01:23h | UTCScience family of journals announces change to open-access policy – Nature
See also: A new mandate highlights costs, benefits of making all scientific articles free to read – Science
Related: Open-access Science Funders Announce Price Transparency Rules for Publishers (several resources on the subject)
Meta-analysis: Comparison of the loop technique with incision and drainage for skin and soft tissue abscesses
20 Jan, 2021 | 01:22h | UTC
Commentary on Twitter
Loop drainage technique (LDT) vs conventional I&D (CID) for cutaneous abscess
8 studies (n=910)
CID failed in 69/487 pts (14%)
LDT failed in 35/423 pts (8%)
OR 2.02 (95% CI 1.29 to 3.18) https://t.co/JVRZWFfyUe@MGottliebMD @GillianMD1 @AcademicEmerMed @SAEMonline #AEM pic.twitter.com/HJfnou4NYc— Gary D Peksa 💊 🌱 (@garyDpeksa) October 15, 2020
Epidural corticosteroid injections for sciatica: An abridged Cochrane systematic review and meta-analysis
20 Jan, 2021 | 01:16h | UTCSource: EvidenceAlerts
Randomized Trial of Focused Ultrasound Subthalamotomy for Parkinson’s Disease
20 Jan, 2021 | 01:20h | UTC
Post-resuscitation shock: Recent advances in pathophysiology and treatment
20 Jan, 2021 | 01:18h | UTC
Role of imaging in visceral vascular emergencies
20 Jan, 2021 | 01:14h | UTCRole of imaging in visceral vascular emergencies – Insights into Imaging
Systematic review: Insufficient evidence of benefit from immediate‐release methylphenidate for attention deficit hyperactivity disorder (ADHD) in adults
20 Jan, 2021 | 01:11h | UTCIR methylphenidate for attention deficit hyperactivity disorder (ADHD) in adults – Cochrane Library
Original study: Immediate‐release methylphenidate for attention deficit hyperactivity disorder (ADHD) in adults – Cochrane Library
Systematic review: Intra-articular ketamine for postoperative analgesia
20 Jan, 2021 | 01:13h | UTC
Commentary on Twitter
What is the impact of intra-articular ketamine for postoperative analgesia?https://t.co/61ECP4EOZ2#physiatry #rehab #painmanagement #ketamine pic.twitter.com/wEQhUvyd8E
— AJPM&R (@AJPMRjournal) November 16, 2020
Systematic review: Does adding iron to wheat flour reduce anemia and increase iron levels in the general population?
20 Jan, 2021 | 01:10h | UTCOriginal study: Wheat flour fortification with iron and other micronutrients for reducing anaemia and improving iron status in populations – Cochrane Library
Study: Similar length of hospital stay with laparoscopic vs. open gastrectomy for gastric cancer
20 Jan, 2021 | 01:05h | UTCLength of Hospital Stay With Laparoscopic vs Open Gastrectomy for Gastric Cancer – The ASCO Post
Meta-analysis: Bisphosphonates or RANK‐ligand‐inhibitors for men with prostate cancer and bone metastases
20 Jan, 2021 | 01:09h | UTC
WHO chief warns against ‘catastrophic moral failure’ in COVID-19 vaccine access
19 Jan, 2021 | 01:58h | UTCWHO chief warns against ‘catastrophic moral failure’ in COVID-19 vaccine access – United Nations
Commentaries: Vaccine nationalism puts world on brink of ‘catastrophic moral failure’: WHO chief – Reuters AND Covid vaccine: WHO warns of ‘catastrophic moral failure’ – BBC
IDH inhibitor Ivosidenib improves overall survival in previously treated patients with cholangiocarcinoma
20 Jan, 2021 | 01:08h | UTC
Postsurgical disease recurrence in stage I to III colorectal cancer may be predicted by ctDNA
20 Jan, 2021 | 01:07h | UTCCommentaries: Postsurgical Disease Recurrence in Stage I to III Colorectal Cancer May Be Predicted by ctDNA – The ASCO Post AND Liquid Biopsy Predicts Colon Cancer Relapse Months Before CT – MedPage Today (free registration required)