All Posts
Review: Deep learning-enabled medical computer vision
22 Jan, 2021 | 08:18h | UTCDeep learning-enabled medical computer vision – npj Digital Medicine
Commentary on Twitter
https://twitter.com/pharmaNGS/status/1347971073221009411
Referral for disease-related visual impairment using retinal photograph-based deep learning: a proof-of-concept, model development study
22 Jan, 2021 | 08:16h | UTCInvited commentary: AI-automated referral for patients with visual impairment – The Lancet Digital Health
Commentary on Twitter
NEW Research: ‘Referral for disease-related visual impairment using #retinal photograph-based #DeepLearning: a proof-of-concept, model development study’. @snec_seri @dukenus @Astarhq @NTUsg @CUHKMedicine @SurajEye @UniHeidelberg @WestmeadInst @NUSMedicinehttps://t.co/iwCwYePLeu pic.twitter.com/Qksm3uPPVu
— The Lancet Digital Health (@LancetDigitalH) December 23, 2020
Predicting the risk of developing diabetic retinopathy using deep learning
22 Jan, 2021 | 08:15h | UTC
Commentary on Twitter
NEW Research: 'Predicting the risk of developing diabetic #retinopathy using deep learning'. #diabetes #DeepLearning @GoogleHealth @AdvClinical @RangsitU https://t.co/fstZJAWu4n pic.twitter.com/qC3AC10i7y
— The Lancet Digital Health (@LancetDigitalH) November 27, 2020
Meta-analysis: Clinical presentation, investigation findings, and treatment outcomes of spontaneous intracranial hypotension syndrome
22 Jan, 2021 | 08:12h | UTC
Commentary on Twitter
This meta-analysis offers a comprehensive and objective summary of the evidence on SIH. Spontaneous intracranial hypotension should not be excluded on the basis of a non-orthostatic headache, normal neuroimaging or normal lumbar puncture opening pressure https://t.co/BcVk2ftcs3
— JAMA Neurology (@JAMANeuro) January 4, 2021
Diagnosis and risk stratification in hypertrophic cardiomyopathy using machine learning wall thickness measurement: a comparison with human test-retest performance
22 Jan, 2021 | 08:13h | UTC
Commentary on Twitter
Superhuman AI measures #HCM wall thickness better than all tested international experts. https://t.co/zjjVaFSGoo Congratulations Rhodri and team. @LancetDigitalH #EACVI#AI #WHYCMR @SCMRorg @UCL @NHSBartsHealth @dr_manisty @JoaoLCavalcante @DesaiMilindY @s_e_petersen @chiarabd pic.twitter.com/hw9R17OYHP
— James moon (@JccmoonMoon) December 4, 2020
International consensus on a standard set of outcome measures for child and youth anxiety, depression, obsessive-compulsive disorder, and post-traumatic stress disorder
22 Jan, 2021 | 08:11h | UTCInternational consensus on a standard set of outcome measures for child and youth anxiety, depression, obsessive-compulsive disorder, and post-traumatic stress disorder – The Lancet Psychiatry (free registration required)
Commentary on Twitter (Thread – Click for more)
1) Delighted to announce the publication of our @TheLancetPsych paper presenting first international consensus on outcomes to track in routine care for children & youth with anxiety/depression. @ICHOM_ORG @mirandarwolpert #MHOutcomes.https://t.co/izFD2j9J2f pic.twitter.com/8as1npIpKE
— Karolin Krause (@KrauseKarolin) December 18, 2020
Pharmacological and non-pharmacological therapeutic strategies in difficult-to-treat rheumatoid arthritis: a systematic literature review informing the EULAR recommendations for the management of difficult-to-treat rheumatoid arthritis
22 Jan, 2021 | 08:08h | UTC
Randomized trial: Standard vs. long peripheral catheters for multiday IV therapy in children
22 Jan, 2021 | 08:05h | UTCStandard Versus Long Peripheral Catheters for Multiday IV Therapy: A Randomized Controlled Trial – Pediatrics (link to abstract – $ for full-text)
Meta-analysis: Prevalence of postural hypotension in primary, community and institutional care
22 Jan, 2021 | 08:09h | UTC
Meta-analysis: Outcomes of endotracheal suctioning in non-vigorous neonates born through meconium-stained amniotic fluid
22 Jan, 2021 | 08:04h | UTC
Commentary on Twitter
Outcomes of non-endotracheal suctioning (non-ETS) versus ETS in non-vigorous meconium-stained neonates = no difference
Published in @ADC_FN https://t.co/raRs4uj73o pic.twitter.com/AAGQiKyc5a
— Evidence-Based Neo (@EBNEO) June 25, 2020
Contradicting earlier trials, Tocilizumab did not improve outcomes, with signs of harm, in patients with severe Covid-19
21 Jan, 2021 | 01:46h | UTCCommentaries: Conflicting COVID-19 results for Roche arthritis drug show more trials needed – Reuters AND Covid-19: Arthritis drug trial for severe illness is stopped early after increase in deaths – The BMJ
Related research (study and commentaries): [Preprint] Randomized trial: Arthritis drugs improve survival in critically ill patients with Covid-19
Meta-analysis of randomized trials: Closed incision negative pressure wound therapy decreases surgical site infections compared to standard dressings after revision total joint arthroplasty, but not primary total joint arthroplasty
22 Jan, 2021 | 08:02h | UTCClosed Incision Negative Pressure Wound Therapy for Elective Hip and Knee Arthroplasty: A Systematic Review and Meta-Analysis of Randomized Controlled Trials – Journal of Arthroplasty (link to abstract – $ for full-text)
Randomized trial of Irinotecan and Cetuximab with or without Vemurafenib in BRAF-Mutant metastatic colorectal cancer
22 Jan, 2021 | 07:57h | UTCCommentary: Triple chemotherapy combination improves metastatic colorectal cancer outcomes – SWOG AND Three Drugs Top Two for BRAF+ Metastatic Colorectal Cancer – MedPage Today
Randomized trial: Benralizumab effects on health-related quality of life, exacerbation rate, lung function, and nasal polyposis symptoms for patients with severe eosinophilic asthma
22 Jan, 2021 | 07:59h | UTCOnset of effect and impact on health-related quality of life, exacerbation rate, lung function, and nasal polyposis symptoms for patients with severe eosinophilic asthma treated with benralizumab (ANDHI): a randomised, controlled, phase 3b trial – The Lancet Respiratory Medicine (link to abstract – $ for full-text)
Commentary on Twitter
NEW Research—#Benralizumab significantly reduced exacerbation risk by 49% vs placebo (RR estimate 0·51, 95% CI 0·39–0·65; p≤0·0001) over the 24-week treatment period in patients with severe eosinophilic #asthma
The ANDHI study from Tim Harrison & co https://t.co/bQwikpQZvc pic.twitter.com/sS9ab0Mo1R
— The Lancet Respiratory Medicine (@LancetRespirMed) January 4, 2021
Final overall survival results of the IDEA Collaboration: 3 vs 6 months of adjuvant chemotherapy for Stage III Colon Cancer
22 Jan, 2021 | 07:58h | UTCOriginal article: Effect of duration of adjuvant chemotherapy for patients with stage III colon cancer (IDEA collaboration): final results from a prospective, pooled analysis of six randomised, phase 3 trials – The Lancet Oncology (link to abstract – $ for full-text)
Commentary on Twitter
https://twitter.com/NatRevClinOncol/status/1334157879767568384
‘A bloody mess’: Confusion reigns over naming of new COVID variants
21 Jan, 2021 | 01:27h | UTC‘A bloody mess’: Confusion reigns over naming of new COVID variants – Nature
[Preprint] South African COVID-19 variant escapes neutralization by antibodies in COVID-19 convalescent plasma
21 Jan, 2021 | 01:28h | UTCSARS-CoV-2 501Y.V2 escapes neutralization by South African COVID-19 donor plasma – bioRxiv
Commentaries: Expert reaction to preprint reporting that the South African SARS-CoV-2 variant 501Y.V2 escapes neutralisation by COVID-19 donor plasma – Science Media Centre AND S.Africa virus strain poses ‘re-infection risk’: study – MedicalXpress
5 reasons to wear a mask even after you’re vaccinated
21 Jan, 2021 | 01:24h | UTC5 Reasons to Wear a Mask Even After You’re Vaccinated – Kaiser Health News
COVID’s toll on smell and taste: what scientists do and don’t know
21 Jan, 2021 | 01:26h | UTCCOVID’s toll on smell and taste: what scientists do and don’t know – Nature
Multi-organ point-of-care ultrasound for COVID-19 (PoCUS4COVID): international expert consensus
21 Jan, 2021 | 01:19h | UTC
Vaccinology in the post−COVID-19 era
21 Jan, 2021 | 01:24h | UTCVaccinology in the post−COVID-19 era – Proceedings of the National Academy of Sciences
Cohort study: Recipients of hematopoietic stem-cell transplantation who develop COVID-19 have poor overall survival
21 Jan, 2021 | 01:18h | UTC
Randomized trial: Similar outcomes with lower vs. higher oxygenation targets for acute hypoxemic respiratory failure
21 Jan, 2021 | 01:16h | UTCLower or Higher Oxygenation Targets for Acute Hypoxemic Respiratory Failure – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary on Twitter
Even though supplemental oxygen is used for the treatment of patients with hypoxemic respiratory failure, the most effective oxygenation targets are not known. In this randomized trial, a lower oxygenation target did not result in lower mortality than a higher target.
— NEJM (@NEJM) January 21, 2021
Allocating scarce intensive care resources during the COVID-19 pandemic: practical challenges to theoretical frameworks
21 Jan, 2021 | 01:22h | UTC
COVID-19 testing: One size does not fit all
21 Jan, 2021 | 01:21h | UTCCOVID-19 testing: One size does not fit all – Science
Commentary on Twitter
COVID-19 testing: One size does not fit all https://t.co/zduxAcrMAA An excellent article by @michaelmina_lab and Kristian Andersen discussing the differences between diagnostic testing, surveillance testing and screening testing.
— Carlos del Rio (@CarlosdelRio7) January 8, 2021


