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RCT: Little benefit from osteopathic manipulative treatment on activity limitations in patients with nonspecific subacute and chronic low back pain
16 Mar, 2021 | 01:39h | UTCEffect of Osteopathic Manipulative Treatment vs Sham Treatment on Activity Limitations in Patients With Nonspecific Subacute and Chronic Low Back Pain: A Randomized Clinical Trial – JAMA Internal Medicine (free for a limited period)
Visual abstract: Effect of Osteopathic Manipulative Treatment vs Sham Treatment on Activity Limitations in Patients With Nonspecific Subacute and Chronic Low Back Pain
M-A: Assessment of postnatal corticosteroids for the prevention of bronchopulmonary dysplasia in preterm neonates
16 Mar, 2021 | 01:38h | UTCAssessment of Postnatal Corticosteroids for the Prevention of Bronchopulmonary Dysplasia in Preterm Neonates: A Systematic Review and Network Meta-analysis – JAMA Pediatrics (free for a limited period)
Editorial: The Swinging Pendulum of Postnatal Corticosteroid Use (free for a limited period)
Update on the safety of COVID-19 Vaccine AstraZeneca
16 Mar, 2021 | 02:35h | UTCUpdate on the safety of COVID-19 Vaccine AstraZeneca
Related: Countries should continue AstraZeneca rollout: WHO – MedicalXpress AND Expert reaction to news that Germany has halted vaccinations with the Oxford-AstraZeneca COVID-19 vaccine – Science Media Centre AND AstraZeneca finds no evidence of increased blood clot risk from vaccine – Reuters AND Data suggest no increased risk of blood clots from the AstraZeneca vaccine. Australia shouldn’t pause its rollout – The Conversation
Commentary on Twitter
As of March 8th, Around 17 million people in the EU & UK received the vaccine , there have been 15 events of DVT & 22 events of pulmonary embolism reported among those given the vaccine,This is much lower than would be expected to occur naturally in a general population
Please RT https://t.co/tnn4brxwpp— Antibiotic Steward Bassam Ghanem 🅱️C🆔🅿️🌟 (@ABsteward) March 14, 2021
B.1.1.7 variant linked to 55% higher mortality compared to other strains of SARS-CoV-2
16 Mar, 2021 | 02:32h | UTCOriginal study: Increased mortality in community-tested cases of SARS-CoV-2 lineage B.1.1.7 – Nature
Related: Death rate 64% higher with B117 COVID variant, study finds (study and commentary)
Commentary on Twitter (thread – Click for more)
https://mobile.twitter.com/_nickdavies/status/1371441682089132032
Antibody response after SARS-CoV-2 infection and implications for immunity: A rapid living review
16 Mar, 2021 | 02:30h | UTC
ACP Practice Points: What is the antibody response and role in conferring natural immunity after SARS-CoV-2 infection?
16 Mar, 2021 | 02:29h | UTC
Assessing risk for healthcare workers during the covid-19 pandemic
16 Mar, 2021 | 02:25h | UTCAssessing risk for healthcare workers during the covid-19 pandemic – The BMJ
Commentary on Twitter
NEW #BMJEducation article discusses how employers can assess risks for healthcare workers during the #COVID19 pandemic. @Azeem_Majeed @kamleshkhunti @RaoMala @CNagpaul Amanda Griffiths https://t.co/YbpZhrLsmz pic.twitter.com/e3TU56EQqH
— The BMJ (@bmj_latest) March 15, 2021
The first 12 months of COVID-19: a timeline of immunological insights
16 Mar, 2021 | 02:22h | UTCThe first 12 months of COVID-19: a timeline of immunological insights – Nature Reviews Immunology
Commentary on Twitter
We've learned a lot on the immune response and multiple discoveries throughout the covid-19 pandemic and I can't imagine it could be better summarized than by this new @NatRevImmunol paper or these authors @CyrilPedia @florian_krammer @VirusesImmunity https://t.co/6SOSP5URFf pic.twitter.com/nOCTOzmzBY
— Eric Topol (@EricTopol) March 15, 2021
Nature Series: Preparing for the next pandemic
16 Mar, 2021 | 02:19h | UTCPreparing for the next pandemic – Nature Medicine
Commentary on Twitter
Preparing for the next pandemic. A terrific collection of more than a dozen papers out today @NatureMedicine https://t.co/oQWy6q3qYs by so many of the people and labs who have guided us through the current one, including @devisridhar @gmleunghku @Baric_Lab
— Eric Topol (@EricTopol) March 15, 2021
Cartoons that explain how the COVID vaccines work
16 Mar, 2021 | 02:13h | UTCCartoons that explain how the COVID vaccines work – KevinMD
More than half of COVID-19 patients report depressive symptoms months later, study finds
16 Mar, 2021 | 02:11h | UTCOriginal study: Association of Acute Symptoms of COVID-19 and Symptoms of Depression in Adults – JAMA Network Open
Commentary on Twitter
Survey study finds 52% of individuals with prior #COVID19 met criteria for moderate or greater symptoms of depression; more likely in younger, male, and those with more severe #COVID19 @royperlis @HarvardMed @Ognyanova @RutgersU @NorthwesternU @dellavolpe https://t.co/4krNvFb29T
— JAMA Network Open (@JAMANetworkOpen) March 13, 2021
Perspective | Prioritizing peritoneal catheter placement during the COVID-19 pandemic
16 Mar, 2021 | 02:16h | UTC
Commentary on Twitter
Individuals receiving dialysis are at high risk of COVID-19 infection, but promoting peritoneal dialysis is one potential way to substantially lower the risk. This perspective outlines how COVID-19 has changed the importance of timely PD catheter insertion https://t.co/Sy2pUShfNU pic.twitter.com/GueiogpO5b
— CJASN (@CJASN) March 12, 2021
Systematic Review: Encephalitis induced by immune checkpoint inhibitors
16 Mar, 2021 | 01:36h | UTCEncephalitis Induced by Immune Checkpoint Inhibitors: A Systematic Review – JAMA Neurology
Editorial: How I prescribe continuous renal replacement therapy
16 Mar, 2021 | 01:27h | UTCHow I prescribe continuous renal replacement therapy – Critical Care
Best practice recommendations for stroke patients with dysphagia
16 Mar, 2021 | 01:26h | UTC
The oxygen cascade during exercise in health and disease
16 Mar, 2021 | 01:28h | UTCThe Oxygen Cascade During Exercise in Health and Disease – Mayo Clinic Proceedings
M-A: Effects of influenza vaccine on mortality and cardiovascular outcomes in patients with cardiovascular disease
14 Mar, 2021 | 20:25h | UTC
Revisiting the Ten Commandments of Emergency Medicine: A Resident’s Perspective
14 Mar, 2021 | 20:26h | UTCRevisiting the Ten Commandments of Emergency Medicine: A Resident’s Perspective – Annals of Emergency Medicine (free for a limited period)
Commentary: Ten Commandments of Emergency Medicine Revisited – Journal Feed
Phase 2 RCT: Donanemab in early Alzheimer’s Disease
14 Mar, 2021 | 20:21h | UTCDonanemab in Early Alzheimer’s Disease – New England Journal of Medicine (link to abstract – $ for full-text)
Commentaries: Experimental Alzheimer’s drug could slow cognitive decline in patients, early results suggest – CNN AND Alzheimer’s study shows mixed results for Lilly’s donanemab on secondary outcomes – First World Pharma
Commentary on Twitter
In a phase 2 trial, patients with early Alzheimer’s disease who received donanemab, an antibody that targets amyloid deposits, showed a better composite score for cognition & ability to perform activities of daily living at 76 weeks than those who received placebo. #ADPD2021
— NEJM (@NEJM) March 13, 2021
Perspective | New lung cancer screening guideline comes with many caveats
14 Mar, 2021 | 20:23h | UTCNew lung cancer screening guideline comes with many caveats – Lown Institute
Original Guideline: USPSTF Statement: begin screening for lung cancer at age 50 years instead of 55 years for patients at risk (article and commentaries)
Clinical trial shows alcohol use disorder recovery can start without sobriety
14 Mar, 2021 | 20:17h | UTC
Commentary on Twitter (thread – click for more)
1/A new trial found a harm reduction treatment effective in reducing drinking in persons experiencing homelessness – from @TheLancetPsych — I was happy to write the editorial—. Press summary here: https://t.co/WoLVWqinm6
— Stefan Kertesz, MD, MSc (@StefanKertesz) March 12, 2021
Resurgence of Ebola Virus disease in Guinea linked to a survivor with virus persistence in seminal fluid for more than 500 days
14 Mar, 2021 | 20:15h | UTCCommentaries: Bombshell analysis traces new Ebola outbreak to survivor of West Africa crisis – STAT AND New Ebola outbreak likely sparked by a person infected 5 years ago – Science AND Ebola survivors can pass on the virus: we’re trying to understand what role sex plays – The Conversation AND The latest Ebola outbreak may have started with someone infected years ago – Science News
Review: Transcatheter Aortic Valve Replacement in Bicuspid Aortic Valve Stenosis
14 Mar, 2021 | 20:11h | UTCTranscatheter Aortic Valve Replacement in Bicuspid Aortic Valve Stenosis – Circulation (free for a limited period)
Commentary on Twitter
Just published in Circulation, a review article in which we discuss the current role and future of TAVR in patients with a bicuspid aortic valvehttps://t.co/nIGlZNBe0D pic.twitter.com/DuavpFoU0p
— Philippe Pibarot (@PPibarot) March 8, 2021
RCT: Efficacy of a combination of conservative therapies vs. an education comparator on clinical outcomes in thumb base osteoarthritis
14 Mar, 2021 | 20:13h | UTCEfficacy of a Combination of Conservative Therapies vs an Education Comparator on Clinical Outcomes in Thumb Base Osteoarthritis: A Randomized Clinical Trial – JAMA Internal Medicine (free for a limited period)
Commentary: Mix of treatments could be way to restore hand function in thumb-base osteoarthritis – University of Sydney
Commentary on Twitter
In people with thumb base #osteoarthritis, a combination of conservative treatments provided small beneficial effects on hand function at 6 weeks, but not pain, compared to an education control. Effects on hand function and pain were greater at 12 weeks https://t.co/lxaIubgTKT
— JAMA Internal Medicine (@JAMAInternalMed) March 9, 2021
New COVID-19 risk calculator can predict severe disease or death among hospitalized patients with COVID-19
14 Mar, 2021 | 20:54h | UTCSee calculator: Severe COVID-19 Adaptive Risk Predictor (SCARP)