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Cohort Study: Selected patients with Covid-19 can be safely discharged on home oxygen, with low mortality and readmission rates

5 Apr, 2021 | 01:52h | UTC

Mortality and Readmission Rates Among Patients With COVID-19 After Discharge From Acute Care Setting With Supplemental Oxygen – JAMA Network Open

Video: Home Oxygen Instructions for Discharged Patients With COVID-19

Commentaries: Covid-19: Ambulatory Management with Home Oxygen Results in Low Mortality, Low Readmissions – Physician’s Weekly AND Mortality, readmission low with COVID-19 discharge on home oxygen – HealthDay

 

Commentaries on Twitter

 


M-A: Secondary prevention of variceal bleeding in adults with previous esophageal variceal bleeding due to decompensated liver cirrhosis

5 Apr, 2021 | 01:17h | UTC

Secondary prevention of variceal bleeding in adults with previous oesophageal variceal bleeding due to decompensated liver cirrhosis: a network meta‐analysis – Cochrane Library

Summary: Prevention of rebleeding from enlarged veins in the food pipe (oesophagus) resulting from advanced liver disease – Cochrane Library

 


How mRNA Technology Could Change the World

5 Apr, 2021 | 01:36h | UTC

How mRNA Technology Could Change the World – The Atlantic (a few articles per month are free)

 


Lamotrigine May Increase Risk for Heart Arrhythmias, FDA Warns

5 Apr, 2021 | 01:12h | UTC

Lamotrigine May Increase Risk for Heart Arrhythmias, FDA Warns – NEJM Journal Watch

FDA Safety Communication: Lamictal (lamotrigine): Drug Safety Communication – Studies Show Increased Risk of Heart Rhythm Problems in Patients with Heart Disease

Related commentary: Epileptologists Push Back on FDA’s New Cardiac Warning for Lamotrigine – Neurology Today

 


Recent progress in the treatment of cancer in children

5 Apr, 2021 | 01:15h | UTC

Recent progress in the treatment of cancer in children – CA: A Cancer Journal for Clinicians

 


Cohort Study: DOACs Safe, Effective in Subset of Valvular AF Patients

5 Apr, 2021 | 01:10h | UTC

DOACs Safe, Effective in Subset of Valvular AF Patients – TCTMD

Original study: Effectiveness and Safety of Direct Oral Anticoagulants Versus Warfarin in Patients With Valvular Atrial Fibrillation: A Population-Based Cohort Study – Annals of Internal Medicine

 


Cohort study: High thrombotic risk in cancer patients receiving immunotherapy

5 Apr, 2021 | 01:08h | UTC

High thrombotic risk in cancer patients receiving immunotherapy – Medical University of Vienna

Original study: Incidence, risk factors, and outcomes of venous and arterial thromboembolism in immune checkpoint inhibitor therapy – Blood

 


Ebola Virus Transmission Initiated by Relapse of Systemic Ebola Virus Disease

5 Apr, 2021 | 01:05h | UTC

Ebola Virus Transmission Initiated by Relapse of Systemic Ebola Virus Disease – New England Journal of Medicine

Related: Resurgence of Ebola Virus disease in Guinea linked to a survivor with virus persistence in seminal fluid for more than 500 days

 

Commentary on Twitter

 


RCT: Postoperative pain control is improved with Methadone + Ketamine vs. Methadone alone in spinal surgical patients

5 Apr, 2021 | 00:49h | UTC

Perioperative Methadone and Ketamine for Postoperative Pain Control in Spinal Surgical Patients: A Randomized, Double-blind, Placebo-controlled Trial – Anesthesiology (link to abstract – $ for full-text)

 

Commentary on Twitter

 


Early outcomes after lung transplantation for severe COVID-19: a series of the first consecutive cases from four countries

5 Apr, 2021 | 01:49h | UTC

Early outcomes after lung transplantation for severe COVID-19: a series of the first consecutive cases from four countries – The Lancet Respiratory Medicine

Commentary: Criteria for selecting COVID-19 patients for lung lung transplantation – Medical University of Vienna

 

Commentary on Twitter

 


Perspective | Concerns about SARS-CoV-2 evolution should not hold back efforts to expand vaccination

5 Apr, 2021 | 01:39h | UTC

Concerns about SARS-CoV-2 evolution should not hold back efforts to expand vaccination – Nature

 

Commentary on Twitter

 


Exceedingly rare side effects reported with AstraZeneca vaccine in the UK – 22 cases of cerebral venous sinus thrombosis with low levels of platelets out of 18 million vaccinated individuals

5 Apr, 2021 | 01:45h | UTC

Covid-19: Seven UK blood clot deaths after AstraZeneca vaccine – BBC

Original report: Coronavirus vaccine – weekly summary of Yellow Card reporting – Medicines and Healthcare products Regulatory Agency

Related opinion: Undermining the AstraZeneca jab is a dangerous act of political folly – The Guardian

“Based on current experience, the expected benefits of both COVID-19 vaccines in preventing COVID-19 and its serious complications far outweigh any known side effects”

 


Using the COVID-19 pandemic to reimagine global health teaching in high-income countries

5 Apr, 2021 | 01:38h | UTC

Using the COVID-19 pandemic to reimagine global health teaching in high-income countries – BMJ Global Health

 

Commentary on Twitter

 


Opinion | The Antiscience Movement Is Escalating, Going Global and Killing Thousands

5 Apr, 2021 | 01:34h | UTC

The Antiscience Movement Is Escalating, Going Global and Killing Thousands – Scientific American

 


Opinion | How to lose friends and alienate people? On the problems of vaccine passports

5 Apr, 2021 | 01:42h | UTC

How to lose friends and alienate people? On the problems of vaccine passports – The BMJ Opinion

Related: Resistance from health experts and business owners could doom ‘vaccine passports’ even before they launch – STAT AND How Vaccine Passports Will Worsen Inequities In Global Health – Microbiology AND Vaccine certificates: does the end justify the means? – The Lancet Microbe AND Covid-19 vaccine passports will harm sustainable development – The BMJ Opinion AND Covid-19 vaccine passports and vaccine hesitancy: freedom or control? – The BMJ Opinion AND “Vaccine Passport” Certification — Policy and Ethical Considerations – New England Journal of Medicine AND Interim position paper: considerations regarding proof of COVID-19 vaccination for international travellers – World Health Organization

 

Commentary on Twitter

 


Many hospitalized Covid-19 patients are given antibiotics. That’s a problem

5 Apr, 2021 | 01:33h | UTC

Many hospitalized Covid-19 patients are given antibiotics. That’s a problem – STAT

 


What we know so far about the effort to vaccinate children

5 Apr, 2021 | 01:31h | UTC

What we know so far about the effort to vaccinate children – National Geographic

 


RCT: Upadacitinib vs. Adalimumab for Psoriatic Arthritis

5 Apr, 2021 | 00:57h | UTC

Trial of Upadacitinib and Adalimumab for Psoriatic Arthritis – New England Journal of Medicine (link to abstract – $ for full-text)

 


RCT: Lumasiran, an RNAi Therapeutic for Primary Hyperoxaluria Type 1

5 Apr, 2021 | 01:01h | UTC

Lumasiran, an RNAi Therapeutic for Primary Hyperoxaluria Type 1 – New England Journal of Medicine (link to abstract – $ for full-text)

 


RCT: Efficacy and safety of a dexamethasone intracanalicular insert in patients with allergic conjunctivitis

5 Apr, 2021 | 00:54h | UTC

Phase 3 Randomized Study of Efficacy and Safety of a Dexamethasone Intracanalicular Insert in Patients With Allergic Conjunctivitis – American Journal of Ophthalmology (link to abstract – $ for full-text)

 


M-A: Similar oncological outcomes with laparoscopic vs. open rectal cancer resections

5 Apr, 2021 | 00:43h | UTC

Oncological outcomes of laparoscopic versus open rectal cancer resections: meta-analysis of randomized clinical trials – British Journal of Surgery

 


Guideline for elective cesarean section: updated systematic review and procedure‐specific postoperative pain management recommendations

2 Apr, 2021 | 09:09h | UTC

PROSPECT guideline for elective caesarean section: updated systematic review and procedure‐specific postoperative pain management recommendations – Anaesthesia

 


RCT: Comparison of two delayed strategies for renal replacement therapy initiation for severe acute kidney injury – waiting too long can be deleterious

2 Apr, 2021 | 09:17h | UTC

Comparison of two delayed strategies for renal replacement therapy initiation for severe acute kidney injury (AKIKI 2): a multicentre, open-label, randomised, controlled trial – The Lancet (link to abstract – $ for full-text)

 


Preliminary study finds a low-calorie diet and mild exercise may improve survival for young people with leukemia

2 Apr, 2021 | 09:12h | UTC

Caloric and nutrient restriction to augment chemotherapy efficacy for acute lymphoblastic leukemia: the IDEAL trial – Blood Advances

Commentary: Low-calorie diet and mild exercise improve survival for young people with leukemia – University of California, Los Angeles (UCLA)

 


Randomized controlled trial compared three antiretroviral regimens started in pregnant women with HIV

2 Apr, 2021 | 09:15h | UTC

Efficacy and safety of dolutegravir with emtricitabine and tenofovir alafenamide fumarate or tenofovir disoproxil fumarate, and efavirenz, emtricitabine, and tenofovir disoproxil fumarate HIV antiretroviral therapy regimens started in pregnancy (IMPAACT 2010/VESTED): a multicentre, open-label, randomised, controlled, phase 3 trial – The Lancet (link to abstract – $ for full-text)

Commentary: ART in pregnant women living with HIV – The Lancet

 


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