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ESC position paper on diagnosis & treatment of cardiac amyloidosis published today simultaneously at EHJ & EJHF. https://t.co/ad7xn7c1MY https://t.co/pZ6tOWICpn @escardio @ESC_Journals @ehj_ed @MarcoMetra
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— Pablo Garcia-Pavia (@dr_pavia) April 7, 2021

Phase 2 RCT: Inhaled budesonide shows promise for the treatment of early COVID-19

12 Apr, 2021 | 01:24h | UTC

Inhaled budesonide in the treatment of early COVID-19 (STOIC): a phase 2, open-label, randomised controlled trial – The Lancet Respiratory Medicine

Commentary: Early treatment with inhaled budesonide to prevent clinical deterioration in patients with COVID-19 – The Lancet Respiratory Medicine

Commentary on Twitter

NEW Research— Early administration of inhaled budesonide reduced the likelihood of needing urgent medical care and reduced time to recovery after early #COVID19

RCT from Mona Bafadhel & colleagues https://t.co/6cJogJs7rp pic.twitter.com/C1dhmTcexP

— The Lancet Respiratory Medicine (@LancetRespirMed) April 10, 2021

RCT: New shorter regimens of benznidazole monotherapy and in combination with fosravuconazole for treatment of Chagas disease

8 Apr, 2021 | 08:47h | UTC

New regimens of benznidazole monotherapy and in combination with fosravuconazole for treatment of Chagas disease (BENDITA): a phase 2, double-blind, randomised trial – The Lancet Infectious Diseases

Commentary: Chagas disease: Shorter treatment just as effective as longer one, according to study in Bolivia published by The Lancet – Drugs for Neglected Diseases Initiative

Perspective: Special diets might boost the power of drugs to vanquish cancers

8 Apr, 2021 | 08:43h | UTC

Special diets might boost the power of drugs to vanquish cancers – Science

NICE Guideline: Assessment and Management of Chronic Pain in Over 16s

8 Apr, 2021 | 08:54h | UTC

Chronic pain (primary and secondary) in over 16s: assessment of all chronic pain and management of chronic primary pain – National Institute for Health and Care Excellence

News release: NICE recommends range of effective treatments for people with chronic primary pain and calls on healthcare professionals to recognise and treat a person’s pain as valid and unique to them

[Preprint] CoronaVac is 50% effective for reducing symptomatic SARS-CoV-2 infection after the first dose in the setting of high P.1 variant transmission in Brazil

9 Apr, 2021 | 03:36h | UTC

Effectiveness of CoronaVac in the setting of high SARS-CoV-2 P.1 variant transmission in Brazil: A test-negative case-control study – medRxiv

Commentary on Twitter (thread – click for more)

New 50% efficacy study of Brazil-predominant vaccine CoronaVac (by Sinovac) in Manaus 🇧🇷 among healthcare workers when #P1 ~75% dominant. Not a trial, but the study found a 1st dose >=14-days efficacy of 50% on symptomatic #COVID19, ~32% if +asymptomatic. https://t.co/YMmZ3mmSDI pic.twitter.com/jwx5R627ys

— Eric Feigl-Ding (@DrEricDing) April 8, 2021

Commentary | Distinguishing the real from the hyperglycemia: does COVID-19 induce diabetes?

9 Apr, 2021 | 03:28h | UTC

Distinguishing the real from the hyperglycaemia: does COVID-19 induce diabetes? – The Lancet Diabetes & Endocrinology

The NIH COVID-19 Treatment Guidelines Panel’s Statement on the Emergency Use Authorization of Anti-SARS-CoV-2 Monoclonal Antibodies for the Treatment of COVID-19

9 Apr, 2021 | 03:35h | UTC

The COVID-19 Treatment Guidelines Panel’s Statement on the Emergency Use Authorization of Anti-SARS-CoV-2 Monoclonal Antibodies for the Treatment of COVID-19 – NIH COVID-19 Treatment Guidelines

Editorial by Dr. Antony Fauci: The story behind COVID-19 vaccines

9 Apr, 2021 | 03:32h | UTC

The story behind COVID-19 vaccines – Science

Large study finds 1 in 3 Covid-19 survivors have subsequent mental health and neurological conditions

8 Apr, 2021 | 09:14h | UTC

6-month neurological and psychiatric outcomes in 236 379 survivors of COVID-19: a retrospective cohort study using electronic health records – The Lancet Psychiatry

Commentaries: 1 in 3 Covid-19 patients are diagnosed with a neuropsychiatric condition in the next six months, large study finds – STAT AND A longer look at COVID-19 and neuropsychiatric outcomes – The Lancet Psychiatry AND Largest study to date suggests link between COVID-19 infection and subsequent mental health and neurological conditions – The Lancet AND Covid-19: One in three has neurological or psychiatric condition diagnosed after covid infection, study finds – The BMJ AND One in three survivors of severe Covid diagnosed with mental health condition – The Guardian AND Covid-19 linked to depression and dementia, study suggests – BBC AND Expert reaction to observational study looking at neurological and psychiatric outcomes 6 months after COVID-19 – Science Media Centre AND 1 in 3 COVID Survivors Struggle With Mental Health Issues Months Later – HealthDay

Commentary on Twitter (thread – click for more)

📍HUGE STUDY—One in 3 #COVID19 survivors received a neurological diagnosis within 6 months of infection—1 in 8 with first ever diagnosis, says study of 230,000 patient records. Also COVID patients had higher risk of dementia, anxiety, Parkinson’s vs flu.🧵https://t.co/BlhtUrOsvL pic.twitter.com/ZAcHZviGKR

— Eric Feigl-Ding (@DrEricDing) April 7, 2021

Audio Interview: Antibody Responses to Natural Infection and Vaccination

9 Apr, 2021 | 03:30h | UTC

Audio Interview: Antibody Responses to Natural Infection and Vaccination – New England Journal of Medicine

Cohort study: One in ten have long-term effects 8 months following mild COVID-19

8 Apr, 2021 | 09:12h | UTC

One in ten have long-term effects 8 months following mild COVID-19 – Karolinska Institutet

Original study: Symptoms and Functional Impairment Assessed 8 Months After Mild COVID-19 Among Health Care Workers – JAMA

Commentary on Twitter

#LongCovid in #Frontline: JAMA

Worrisome! N=323 COVID+ #Healthcare Workers vs. N=1072 w no COVID. At 8 mos, up to 4x risk of fxnl impairment in work, social & home life. REAL ongoing suffering in low-risk humans after #COVID.https://t.co/EwZWdW4ZtL #medtwitter #nurse pic.twitter.com/tofIx4p647

— WesElyMD (@WesElyMD) April 7, 2021