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No evidence yet to suggest Covid vaccine booster is needed, CDC group says.
25 Jun, 2021 | 10:29h | UTCNo evidence yet to suggest Covid vaccine booster is needed, CDC group says – NBC News
Related opinion: 7 Reasons Why We Should Not Need Boosters for COVID-19 – by Monica Ghandi, MD
Long Covid: Half of young adults with COVID-19 have persistent symptoms 6 months after, study finds.
25 Jun, 2021 | 10:33h | UTCOriginal Study: Long COVID in a prospective cohort of home-isolated patients – Nature Medicine
Commentary on Twitter
Analysis of a prospectively enrolled cohort of patients with #SARSCoV2 infections reveals a high proportion who experienced #LongCovid symptoms at 6 months, despite being relatively young and having only mild to moderate acute #COVID19 symptoms https://t.co/fuW2QpfJog
— Nature Medicine (@NatureMedicine) June 23, 2021
Opinion | The mRNA vaccines are extraordinary, but Novavax is even better.
25 Jun, 2021 | 10:24h | UTCThe mRNA Vaccines Are Extraordinary, but Novavax Is Even Better – The Atlantic
Commentary on Twitter
https://twitter.com/hildabast/status/1408175034879733761
RCT: Doxycycline for 7 days superior to single-dose azithromycin for the treatment of rectal chlamydia infection.
25 Jun, 2021 | 10:19h | UTCAzithromycin or Doxycycline for Asymptomatic Rectal Chlamydia trachomatis – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: Doxycycline Superior to Azithromycin for Asymptomatic Rectal Chlamydia in Men – Physician’s Weekly
Commentary on Twitter
Doxycycline is 20% more efficacious than azithromycin for the treatment of rectal chlamydia. Check out the results of our RCT published today in @NEJM.
Azithromycin or Doxycycline for Asymptomatic Rectal Chlamydia trachomatis | NEJM https://t.co/qpjo8VTg8u
— Jane Hocking (@JHocking01) June 23, 2021
Delta COVID variant fuels global surges, complicates reopenings.
25 Jun, 2021 | 10:23h | UTCDelta COVID variant fuels global surges, complicates reopenings – CIDRAP
Perspective | Are Chinese COVID vaccines underperforming? a dearth of real-life studies leaves unanswered questions.
25 Jun, 2021 | 10:26h | UTCRelated: WHO approval of Chinese CoronaVac COVID vaccine will be crucial to curbing pandemic. AND Brazilian town experiment shows mass vaccination can wipe out COVID-19.
Selected issues in sport-related concussion for the team physician: a consensus statement – “Current evidence suggests strict rest after SRC slows recovery and increases the probability of prolonged symptoms”.
25 Jun, 2021 | 10:15h | UTCNews release: Strict Rest Slows Recovery after Sports-Related Concussions – American College of Sports Medicine
IDSA 2021 focused update guidelines on the management of Clostridioides difficile infection in adults.
25 Jun, 2021 | 10:17h | UTCNews release: IDSA And SHEA Release New Guidelines for Managing Clostridium Difficile Infection – Infectious Diseases Society of America
Commentary on Twitter
🆕🔥🔥🔥Clinical Practice Guideline @IDSAInfo @SHEA_Epi 2021 Focused Update Guidelines on Management of CDI in Adults
Major update💥:for patients with an initial CDI episode, guidelines suggest using fidaxomicin rather than a standard course of vancomycin https://t.co/2iqcoTHqLL pic.twitter.com/2uzZamvkkr— Antibiotic Steward Bassam Ghanem 🅱️C🆔🅿️🌟 (@ABsteward) June 24, 2021
Perspective | Why are people with obesity more vulnerable to COVID?
25 Jun, 2021 | 10:21h | UTCWhy Are People with Obesity More Vulnerable to COVID? – Scientific American
CDC advisory panel backs use of dengue vaccine in high-risk areas, despite delivery challenges.
25 Jun, 2021 | 10:13h | UTC
Review | Myocardial perfusion and viability imaging in coronary artery disease: clinical value in diagnosis, prognosis and therapeutic guidance.
25 Jun, 2021 | 10:12h | UTC
Evidence-based clinical practice guidelines for management of colorectal polyps.
25 Jun, 2021 | 10:11h | UTC
Three doses of an mRNA Covid-19 vaccine in solid-organ transplant recipients can improve the immunogenicity of the vaccine.
24 Jun, 2021 | 10:32h | UTC
Another study shows a single dose of an mRNA vaccine has maximal effects in those with past infection.
24 Jun, 2021 | 10:38h | UTCPrimary, Recall, and Decay Kinetics of SARS-CoV-2 Vaccine Antibody Responses – ACS Nano
Related: France recommends single dose of vaccine if previous Covid infection detected. AND [Preprint] More data showing a single-dose SARS-CoV-2 mRNA vaccine may be enough in individuals with previous COVID-19. AND Another study shows a single dose of mRNA vaccine may be enough for patients with previous Covid-19
Commentary on Twitter
Prior covid? Unless it's a severe case, one-dose mRNA vaccine adds considerable protection and nothing added by 2nd dose. This is now concordant w/ >20 studieshttps://t.co/8Qpuw193zk @acsnano pic.twitter.com/TJNbl8HPy9
— Eric Topol (@EricTopol) June 23, 2021
Effect of Vaccination on Household Transmission of SARS-CoV-2 in England – “the likelihood of household transmission was approximately 40 to 50% lower in households of index patients who had been vaccinated 21 days or more before testing positive than in households of unvaccinated index patients”.
24 Jun, 2021 | 09:52h | UTCRelated: Study in England showed one dose of COVID-19 vaccine can cut household transmission by up to half – This protection is on top of the reduced risk of a vaccinated person developing symptomatic infection, which is around 60 to 65% after the first dose AND Covid-19 vaccination prevents transmission from vaccinated to unvaccinated household members.
Report: SARS-CoV-2 variants and vaccines.
24 Jun, 2021 | 10:33h | UTCSARS-CoV-2 Variants and Vaccines – New England Journal of Medicine
Perspective | Delta variant triggers dangerous new phase in the pandemic.
24 Jun, 2021 | 10:43h | UTCDelta variant triggers dangerous new phase in the pandemic – Science
Analysis | Future of covid-19 vaccine pricing: lessons from influenza – “Routine use of covid-19 vaccines could strain health budgets if pricing follows the pattern seen with influenza vaccines”.
24 Jun, 2021 | 09:50h | UTCFuture of covid-19 vaccine pricing: lessons from influenza – The BMJ
Commentary on Twitter
https://twitter.com/hildabast/status/1407469629459468289
CDC: mRNA vaccines are likely linked to cases of myocarditis and pericarditis – 1,226 cases of myocarditis or pericarditis have been reported mostly in people under 30.
24 Jun, 2021 | 09:51h | UTCSee also: Experts: mRNA COVID-19 vaccines likely tied to heart inflammation – CIDRAP
Related: Case series: 7 cases of myocarditis following mRNA-based COVID-19 vaccination. AND Case series: clinical and cardiac magnetic resonance imaging findings of 4 cases of myocarditis following mRNA-based COVID-19 vaccination. AND Case series: symptomatic acute myocarditis in 7 adolescents following mRNA COVID-19 vaccination. AND CDC says heart inflammation cases were higher than expected in 16- to 24-year-olds after second Covid vaccine shot, but still rare. AND Israel reports link between rare cases of heart inflammation and COVID-19 vaccination in young men. AND CDC is investigating several reports that teenagers and young adults may have developed myocarditis after receiving mRNA vaccines. Most cases were mild, more often in males than females, more often following dose 2 than dose 1, and typically, within 4 days after vaccination.
Review | My Treatment Approach to Clostridioides difficile Infection.
24 Jun, 2021 | 09:47h | UTCMy Treatment Approach to Clostridioides difficile Infection – Mayo Clinic Proceedings
Recommendations for the management of incidental pancreatic findings in adults.
24 Jun, 2021 | 09:48h | UTCRelated: Diagnosis and Surveillance of Incidental Pancreatic Cystic Lesions: 2017 Consensus Recommendations of the Korean Society of Abdominal Radiology – Korean Journal of Radiology AND Cohort Study: Incidence, Prevalence and 5-year Pancreatic-related Mortality of Pancreatic Cysts AND Meta-Analysis: Incidental Findings on MRI of Apparently Asymptomatic Adults AND Prevalence and outcomes of incidental imaging findings: umbrella review AND Incidental anarchy – The BMJ Opinion
Opinion | A strategy to reduce the carbon footprint of clinical trials.
24 Jun, 2021 | 09:45h | UTCA strategy to reduce the carbon footprint of clinical trials – The Lancet
Viewpoint | Progress in Pharmacotherapy for Obesity.
24 Jun, 2021 | 09:46h | UTCProgress in Pharmacotherapy for Obesity – JAMA (free for a limited period)
See also: Semaglutide’s Success Could Usher in a “New Dawn” for Obesity Treatment – JAMA (free for a limited period)
Audio clinical review: Semaglutide for Weight Loss
Youth running consensus statement: minimizing risk of injury and illness in youth runners.
24 Jun, 2021 | 09:42h | UTC
Systematic review: low‐dose oral misoprostol probably has many benefits over other methods for labor induction.
24 Jun, 2021 | 09:44h | UTCLow‐dose oral misoprostol for induction of labour – Cochrane Library