All Posts
Position Statement on Endomyocardial Biopsy.
23 Jul, 2021 | 10:33h | UTC
Commentary on Twitter
🚨A must read – out now in JCF: Position Statement on Endomyocardial Biopsy 🫀 – @HFSA @escardio @ESCardioNews #CardioTwitter #FunctionNotFailure #HeartSuccess @rcstarling @MRMehraMD @BiykemB @Filippatos @robmentz @dranulala https://t.co/33FPZDBviN pic.twitter.com/VJEzGLIRIg
— Journal of Cardiac Failure (@JCardFail) July 21, 2021
Opinion | Expanding evidence for clinical care of older adults: beyond clinical trial traditions and finding new approaches.
23 Jul, 2021 | 10:31h | UTCExpanding Evidence for Clinical Care of Older Adults: Beyond Clinical Trial Traditions and Finding New Approaches – JAMA (free for a limited period)
Review: Ethics in extracorporeal life support.
23 Jul, 2021 | 10:29h | UTCEthics in extracorporeal life support: a narrative review – Critical Care
RCT: Dolutegravir or Darunavir in combination with Zidovudine or Tenofovir to treat HIV.
23 Jul, 2021 | 10:25h | UTCDolutegravir or Darunavir in Combination with Zidovudine or Tenofovir to Treat HIV – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: Dolutegravir Confirmed as Effective Second-Line HIV Therapy; Recycling Tenofovir Noninferior to Zidovudine – Medscape (free registration required)
An ESPGHAN Position Paper on the use of breath testing in pediatric gastroenterology.
23 Jul, 2021 | 10:26h | UTC
Survey finds 8% of researchers have falsified or fabricated data.
23 Jul, 2021 | 10:28h | UTC8% of researchers in Dutch survey have falsified or fabricated data – Nature
Original study and commentaries: Landmark research integrity survey finds questionable practices are surprisingly common.
Related: Opinion | Time to assume that health research is fraudulent until proven otherwise? AND How a Data Detective Exposed Suspicious Medical Trials
Study shows AstraZeneca and Pfizer vaccines are effective against Delta variant, but both doses are needed.
22 Jul, 2021 | 11:16h | UTCCommentaries: Study Finds Pfizer And AstraZeneca Vaccines Effective Against The Delta Variant — As Long As You Get Both Doses – Forbes AND Pfizer’s COVID-19 vaccine works very well against the Delta variant — but only after 2 doses – Insider
Related: [Preprint] 2 doses of Covid vaccines (Pfizer-BioNTech or Oxford-AstraZeneca) highly effective against hospitalization from Delta variant. AND Reduced sensitivity of SARS-CoV-2 variant Delta to antibody neutralization. AND Should I get my second AstraZeneca dose? Yes, it almost doubles your protection against Delta.
Commentary on Twitter
https://twitter.com/hildabast/status/1417964189566472195
Consensus Statement: Best practices in the clinical management of progressive supranuclear palsy and corticobasal syndrome.
23 Jul, 2021 | 10:22h | UTCCommentary: Treatment guide for neurodegenerative disorders – Johns Hopkins University
Review: The hemostatic and thrombotic complications of liver disease.
23 Jul, 2021 | 10:23h | UTCThe Hemostatic and Thrombotic Complications of Liver Disease – European Journal of Haematology
COVID-19 antibodies persist at least nine months after infection – “98.8 percent of people infected in February/March showed detectable levels of antibodies in November”.
22 Jul, 2021 | 11:14h | UTCNews release: COVID-19 antibodies persist at least nine months after infection – Imperial College London
Original study: SARS-CoV-2 antibody dynamics and transmission from community-wide serological testing in the Italian municipality of Vo’ – Nature Communications
AAP Policy Statement | Incorporate cardiac risk screening for all youths at least every 3 years.
23 Jul, 2021 | 10:19h | UTCNews release: Policy: Incorporate cardiac risk screening for all youths at least every 3 years – American Academy of Pediatrics
Policy Statement: Sudden Death in the Young: Information for the Primary Care Provider – Pediatrics
RCT: Dapagliflozin in patients with cardiometabolic risk factors hospitalized with COVID-19 – safe, but no statistically significant risk reduction in organ dysfunction or death.
22 Jul, 2021 | 11:08h | UTCCommentary: Dapagliflozin in patients with COVID-19: truth or dare – The Lancet Diabetes & Endocrinology
Should children get COVID vaccines? What the science says.
22 Jul, 2021 | 11:06h | UTCShould children get COVID vaccines? What the science says – Nature
Opinion | The benefits of a COVID vaccine far outweigh the small risk of treatable heart inflammation.
22 Jul, 2021 | 10:57h | UTC
Analysis finds benefits of COVID-19 vaccination outweigh risks of rare cases of myocarditis.
22 Jul, 2021 | 11:05h | UTCNews release: Study finds benefits of COVID-19 vaccination outweigh risks of rare cases of myocarditis – American Heart Association
Original study: Myocarditis with COVID-19 mRNA Vaccines – Circulation
Commentary: Myocarditis and COVID-19 Vaccines: New Review Tackles Knowns, Unknowns – TCTMD
Commentary on Twitter
Just published ahead of print- Myocarditis with Covid mRNA Vaccines https://t.co/mc2yrr5pDV Mechanisms, benefit of COVID-19 mRNA vaccination over low risk, management strategies – review of all myocarditis cases published to date, CDC&other reports @PeterHotez @ishannovation
— BiykemBozkurt (@BiykemB) July 20, 2021
WHO Guidelines for the management of symptomatic sexually transmitted infections.
22 Jul, 2021 | 10:54h | UTCNews release: Launch WHO guidelines for the management of symptomatic sexually transmitted infection – World Health Organization
Commentary on Twitter
Great see @WHO new guidelines #STIs https://t.co/SgkCtcMDbv BUT hope last edition w syndromic management. Must deliver diagnostic capacity LMICs pic.twitter.com/B7ugeUpIRG
— Michael Marks (@dr_michaelmarks) July 17, 2021
Opinion | Kids aren’t just littler adults – here’s why they need their own clinical trials for a COVID-19 vaccine.
22 Jul, 2021 | 10:55h | UTC
RCT: Sintilimab plus a bevacizumab biosimilar versus sorafenib in unresectable hepatocellular carcinoma.
22 Jul, 2021 | 10:47h | UTCSintilimab plus a bevacizumab biosimilar (IBI305) versus sorafenib in unresectable hepatocellular carcinoma (ORIENT-32): a randomised, open-label, phase 2–3 study – The Lancet Oncology (link to abstract – $ for full-text)
Commentary on Twitter
In a phase III trial involving 571 pts with unresectable HCC, the anti-PD-1 mAb sintilimab + the bevacizumab biosimilar IBI305 improved PFS (median 4.6 vs 2.8 months with sorafenib; HR 0.56, P <0.0001) & OS (median NR vs 10.4 months; HR 0.57, P <0.0001), https://t.co/UF43FGdMMy
— NatureRevClinOncol (@NatRevClinOncol) June 22, 2021
Review: The routes of administration for acute postoperative pain medication.
22 Jul, 2021 | 10:46h | UTCThe Routes of Administration for Acute Postoperative Pain Medication – Pain and Therapy
Oncology Medical Home: ASCO and COA Standards – “The OMH model is a system of care delivery that features coordinated, efficient, accessible, and evidence-based care and includes a process for measurement of outcomes to facilitate continuous quality improvement”.
22 Jul, 2021 | 10:49h | UTCOncology Medical Home: ASCO and COA Standards – JCO Oncology Practice
Commentary: Oncology Organizations Release New Standards for Medical Home Care – Pharmacy Times
Systematic review: Breast Reconstruction After Mastectomy.
22 Jul, 2021 | 10:45h | UTCBreast Reconstruction After Mastectomy – Agency for Healthcare Research and Quality
RCT: Progressive exercise compared with best practice advice, with or without corticosteroid injection, for the treatment of patients with rotator cuff disorders.
22 Jul, 2021 | 10:42h | UTCCommentaries: Optimising treatment for patients with rotator cuff disorders – The Lancet (free registration required)
Commentary on Twitter (thread – click for more)
The much-anticipated GRASP trial for rotator cuff pain has just been published showing steroid injections have a small short-lasting benefit, and that physio led exercise was no better than patient led exercise… Here's my short Twitter review… 1/12 https://t.co/1TFYGoAi7X
— The Sp⚽️rts Physio (@AdamMeakins) July 13, 2021
Review: Personalized mechanical ventilation in acute respiratory distress syndrome.
22 Jul, 2021 | 10:40h | UTCPersonalized mechanical ventilation in acute respiratory distress syndrome – Critical Care
Related: M-A of randomized trials: In patients with acute respiratory distress syndrome, there was no difference in mortality between higher vs. lower positive end-expiratory pressure strategies. AND Seminar | Acute respiratory distress syndrome. AND Short review: Diagnosis and management of acute respiratory distress syndrome
RCT: Immediate oral refeeding in patients with mild and moderate acute pancreatitis.
22 Jul, 2021 | 10:32h | UTCImmediate Oral Refeeding in Patients With Mild and Moderate Acute Pancreatitis: A Multicenter, Randomized Controlled Trial (PADI trial) – Annals of Surgery (link to abstract – $ for full-text)
Guideline on the management of IgE-mediated food allergies.
22 Jul, 2021 | 10:34h | UTCUpdate of the S2k guideline on the management of IgE-mediated food allergies – Allergologie Select