All Posts
Cohort Study | Stopping immunotherapy in patients that are progression-free at 2 years seems feasible in advanced NSCLC
21 Jun, 2023 | 13:19h | UTCAssociation Between Duration of Immunotherapy and Overall Survival in Advanced Non–Small Cell Lung Cancer – JAMA Oncology (link to abstract – $ for full-text)
Commentary on Twitter
Study of patients with #NSCLC showed no survival difference between 2-yr fixed duration vs indefinite #immunotherapy, suggesting that IO can be d/c at 2 yrs. @PennCancer @flatironhealth @lovasunMD @Ron_cology @CharuAggarwalMD #ASCO23 https://t.co/EWyneghc8a pic.twitter.com/HkyIwwtJiM
— JAMA Oncology (@JAMAOnc) June 4, 2023
Review | Traumatic hemorrhage and chain of survival
21 Jun, 2023 | 13:17h | UTC
RCT | Rituximab and MMF combo improves lung function vs. MMF in interstitial lung disease with NSIP pattern, but may increase infection risk
21 Jun, 2023 | 13:16h | UTCRituximab and mycophenolate mofetil combination in patients with interstitial lung disease (EVER-ILD): a double-blind, randomised, placebo-controlled trial – European Respiratory Journal (link to abstract – $ for full-text)
Commentary on Twitter
ERJ: Rituximab plus MMF is associated with benefits in lung function and progression-free survival compared with MMF plus placebo after 24 weeks of treatment. The safety profile of rituximab plus MMF was similar to that of MMF plus placebo. https://t.co/Mv0IuzLljz pic.twitter.com/1igrt6uDK4
— ERS publications (@ERSpublications) June 11, 2023
Review | Glomerular hematuria and the utility of urine microscopy
21 Jun, 2023 | 13:14h | UTC
Commentary on Twitter
Glomerular Hematuria and the Utility of Urine Microscopy: A Reviewhttps://t.co/SsibhaJqnY (FREE)
@MLReynoldsMD @AmyMottl @ANCAUNC @VDereBean pic.twitter.com/kEhmKSL2Ij
— AJKD (@AJKDonline) June 11, 2023
Review | Ultrasonographic assessment of diaphragmatic function in the management of patients with acute respiratory failure
21 Jun, 2023 | 13:12h | UTC
Review | Pulmonary rehabilitation and physical interventions
21 Jun, 2023 | 13:11h | UTCPulmonary rehabilitation and physical interventions – European Respiratory Review
Commentary on Twitter
ERR: Pulmonary rehabilitation that includes individualised exercise training is effective in patients with stable COPD and those who have suffered an exacerbation. Remaining challenges are to increase uptake and access to and personalisation of programmes. https://t.co/NSoASus6TW pic.twitter.com/JRl7dCOZrm
— ERS publications (@ERSpublications) June 12, 2023
The foot in diabetes – a reminder of an ever-present risk
21 Jun, 2023 | 13:10h | UTCThe foot in diabetes – a reminder of an ever-present risk – Clinical Medicine Journal
Related: Guideline Series | Prevention and management of diabetes-related foot disease
RCT | Use of lumbar drains improves 6-month outcomes in patients with aneurysmal subarachnoid hemorrhage
20 Jun, 2023 | 12:55h | UTCSee also: Visual Abstract
Commentary on Twitter
In this trial, among patients with aneurysmal subarachnoid hemorrhage, lumbar drainage improved clinical neurological outcomes at 6 months. https://t.co/SZjuQoGoku pic.twitter.com/szKcZaPL9K
— JAMA Neurology (@JAMANeuro) June 18, 2023
RCT | In chronic subdural hematoma, dexamethasone fails to match surgery for functional outcomes
20 Jun, 2023 | 12:53h | UTCDexamethasone versus Surgery for Chronic Subdural Hematoma – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: Dexamethasone Compared to Burr-Hole Drainage for Chronic Subdural Hematoma – HealthDay
RCT | No superior recovery with minithoracotomy over sternotomy in mitral valve repair
20 Jun, 2023 | 12:51h | UTCMinithoracotomy vs Conventional Sternotomy for Mitral Valve Repair: A Randomized Clinical Trial – JAMA (free for a limited period)
See also: Visual Abstract
Opinion | Strategic masking to protect patients from all respiratory viral infections
20 Jun, 2023 | 12:50h | UTCStrategic Masking to Protect Patients from All Respiratory Viral Infections – New England Journal of Medicine (link to abstract – $ for full-text)
RCT | Thrice-weekly oral iron shows non-inferiority and fewer gastrointestinal effects in treating iron-deficiency anemia
20 Jun, 2023 | 12:48h | UTCA randomized controlled trial of thrice-weekly versus thrice-daily oral ferrous fumarate treatment in adult patients with iron-deficiency anemia – Ann Hematol (if the link is paywalled, try this one)
Guideline | Management of patients with primary spontaneous pneumothorax
20 Jun, 2023 | 12:46h | UTC
Scientific Statement | Hormones and aging
20 Jun, 2023 | 12:45h | UTCNews Release: Endocrine Society Scientific Statement distinguishes normal aging from endocrine disease – Endocrine Society
Guidelines for the management of trigeminal neuralgia
20 Jun, 2023 | 12:43h | UTCGuidelines for the management of trigeminal neuralgia – Cleveland Clinic Journal of Medicine
Review | Measuring exhaled nitric oxide when diagnosing and managing asthma
20 Jun, 2023 | 12:41h | UTC
Cohort Study | Five-year safety and efficacy of leadless pacemakers
20 Jun, 2023 | 12:40h | UTCFive-year safety and efficacy of leadless pacemakers in a Dutch cohort – Heart Rhythm
RCT | Hemostatic powder provides better control of gastrointestinal tumor bleeding than standard endoscopic treatment
20 Jun, 2023 | 12:39h | UTCHemostatic powder vs. standard endoscopic treatment for gastrointestinal tumor bleeding: A multicenter randomized trial – Gastroenterology (link to abstract – $ for full-text)
Consensus Paper | Management of febrile neutropenia in pediatric hematology and oncology patients
20 Jun, 2023 | 12:38h | UTC
Review | Updates in immunohistochemistry for hematopoietic and lymphoid neoplasms
20 Jun, 2023 | 12:36h | UTC
RCT | Avapritinib superior to placebo in reducing symptoms, mast-cell burden in indolent systemic mastocytosis patients
20 Jun, 2023 | 12:34h | UTCAvapritinib versus Placebo in Indolent Systemic Mastocytosis – NEJM Evidence
Commentary on Twitter
“…in this 24-week blinded phase of the PIONEER trial, avapritinib demonstrated superiority to placebo in improving symptoms in patients with moderate to severe symptomatic ISM [indolent systemic mastocytosis]….”#Oncology #ClinicalTrials @StanfordDeptMed @ProfMaurer
— NEJM Evidence (@NEJMEvidence) June 15, 2023
Guideline | Screening and diagnosis of significant hemoglobinopathies
20 Jun, 2023 | 12:32h | UTC
Podcast | Inpatient cirrhosis management
20 Jun, 2023 | 12:30h | UTC# 398:Live! From SHM: Inpatient Cirrhosis Management – The Curbsiders
M-A | Stenting or angioplasty show little to no improvement over best medical practice in acute DVT treatment
20 Jun, 2023 | 12:29h | UTC
SR | Triage and diagnostic accuracy of online symptom checkers
20 Jun, 2023 | 12:27h | UTC