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M-A: Predictors of permanent pacemaker implantation in patients undergoing transcatheter aortic valve replacement.

15 Oct, 2021 | 02:19h | UTC

Predictors of Permanent Pacemaker Implantation in Patients Undergoing Transcatheter Aortic Valve Replacement ‐ A Systematic Review and Meta‐Analysis – Journal of the American Heart Association

 

Commentary on Twitter

 

Trastuzumab for early-stage, HER2-positive breast cancer: a meta-analysis of 13 864 women in seven randomized trials.

15 Oct, 2021 | 02:07h | UTC

Trastuzumab for early-stage, HER2-positive breast cancer: a meta-analysis of 13 864 women in seven randomised trials – The Lancet Oncology

 

Commentary on Twitter

https://twitter.com/NicoleKuderer/status/1423002503138795521

 

Cohort study: Among women with congenital Long QT, progestin oral contraceptives were linked to a 2.8-fold increased risk of cardiovascular events in those not receiving B-blocker therapy.

15 Oct, 2021 | 02:17h | UTC

Use of oral contraceptives in women with congenital long QT syndrome – Heart Rhythm (link to abstract – $ for full-text)

Commentary: Progestin OCs Triple CV Events in Women With Congenital Long QT – TCTMD

 

Autoimmune encephalitis–related seizures and epilepsy: diagnostic and therapeutic approaches.

15 Oct, 2021 | 02:08h | UTC

Autoimmune Encephalitis–Related Seizures and Epilepsy: Diagnostic and Therapeutic Approaches – Mayo Clinic Proceedings

 

Commentary on Twitter

 

Ray Moynihan: Ten things I wish I’d been told as a junior academic.

15 Oct, 2021 | 02:13h | UTC

Ray Moynihan: Ten things I wish I’d been told as a junior academic – The BMJ Opinion

 

Intracerebral hemorrhage: diagnosis, emergency management, and prognosis.

15 Oct, 2021 | 02:12h | UTC

Intracerebral Hemorrhage: Diagnosis, Emergency Management, and Prognosis – emDocs

 

How to be a good science communicator.

14 Oct, 2021 | 10:13h | UTC

How to be a good science communicator – Nature Medicine

 

Commentary on Twitter

 

Systematic Review: Short-term and long-term rates of postacute sequelae of SARS-CoV-2 infection.

14 Oct, 2021 | 10:15h | UTC

Short-term and Long-term Rates of Postacute Sequelae of SARS-CoV-2 Infection: A Systematic Review – JAMA Network Open

Commentaries:

Most COVID-19 survivors have symptoms 6 months on, review finds – CIDRAP

Expert reaction to systematic review on rates of postacute sequelae of SARS-CoV-2 infection (PASC) – Science Media Centre

How many people get ‘long COVID’? More than half, researchers find – Penn State

Related:

WHO Consensus: A clinical case definition of post COVID-19 condition (Long Covid).

Characterizing long COVID: a living systematic review.

Long Covid – The illness narratives.

New guidelines to help doctors manage long COVID patients published.

M-A: More than 50 long-term effects of COVID-19. (several articles on the subject)

 

Commentary on Twitter

 

Video: Merck’s Covid pill could transform treatment. Here’s how it works.

14 Oct, 2021 | 10:10h | UTC

Watch: Merck’s Covid pill could transform treatment. Here’s how it works – STAT

Related:

How antiviral pill Molnupiravir shot ahead in the COVID drug hunt.

What we know — and don’t know — about Merck’s new Covid-19 pill.

[Press release – not published yet] Merck announces oral antiviral Molnupiravir reduced the risk of hospitalization or death by approximately 50 Percent compared to placebo for patients with mild or moderate COVID-19.

Merck’s Covid-19 pill is great news but may not be a game-changer.

Video | A Pill For COVID? A Doctor Explains Molnupiravir.

 

[Preprint] In RCT with 29,949 participants, the Novavax vaccine demonstrated high overall efficacy (>90%) for the prevention of Covid-19, and all moderate-to-severe cases occurred in placebo recipients.

14 Oct, 2021 | 10:17h | UTC

Efficacy and Safety of NVX-CoV2373 in Adults in the United States and Mexico – medRxiv

Commentary: Novel vaccine demonstrates high efficacy for prevention of COVID-19 – News Medical

Related:

RCT: Novavax vaccine conferred 89.7% protection against symptomatic SARS-CoV-2 infection and 100% protection against hospitalizations or deaths.

Opinion | The mRNA vaccines are extraordinary, but Novavax is even better.

(Press release – not published yet) Novavax COVID-19 vaccine demonstrates 90% overall efficacy and 100% protection against moderate and severe disease.

RCT: Novavax vaccine is 49.4% effective against B.1.351 SARS-CoV-2 variant.

[Press release – not published yet] Novavax reports 96% efficacy against original strain of COVID-19, 86% efficacy against B.1.1.7 variant, and 55% efficacy against B1.351 variant

New COVID-19 vaccines: here’s how the promising Novavax and Johnson & Johnson jabs work

Covid-19: Novavax vaccine efficacy is 86% against UK variant and 60% against South African variant

 

Commentary on Twitter

 

WHO provides guidance to address the shortage of quality palliative care services.

14 Oct, 2021 | 09:59h | UTC

News release: WHO takes steps to address glaring shortage of quality palliative care services – World Health Organization

See Guidance:

Assessing the development of palliative care worldwide: a set of actionable indicators – World Health Organization

Quality health services and palliative care: practical approaches and resources to support policy, strategy and practice – World Health Organization

 

Commentary on Twitter (thread – click for more)

 

How Covax failed on its promise to vaccinate the world – “Covax, described as “naively ambitious” by one expert, has contributed just 5% of all vaccines administered globally”.

14 Oct, 2021 | 10:12h | UTC

How Covax failed on its promise to vaccinate the world – The Bureau of Investigative Journalism

Related:

Perspective | A beautiful idea: how COVAX has fallen short.

WHO Launches Strategy to Achieve Global Covid-19 Vaccination by mid-2022.

WHO special envoys: To beat Covid, there’s a simple lesson – no one’s safe until everyone’s safe.

Joint COVAX Statement on the Equal Recognition of Vaccines – COVAX urges all government authorities to recognize as fully vaccinated all people who have received COVID-19 vaccines that have been deemed safe and effective by WHO.

WHO COVAX Joint Statement: Call to action to equip COVAX to deliver 2 billion doses in 2021.

Covax: How will Covid vaccines be shared around the world?

 

Home Hemodialysis: Core Curriculum 2021.

14 Oct, 2021 | 09:55h | UTC

Home Hemodialysis: Core Curriculum 2021 – American Journal of Kidney Diseases

 

Commentary on Twitter

 

ASH 2021 guidelines for stem cell transplantation in patients with sickle cell disease.

14 Oct, 2021 | 09:53h | UTC

American Society of Hematology 2021 guidelines for sickle cell disease: stem cell transplantation – Blood

News release: ASH Releases New Clinical Practice Guidelines on Stem Cell Transplantation in Sickle Cell Disease

Commentary: ASH Issues Guideline on the Use of HSCT for Sickle Cell Disease – HealthDay

 

Podcast with Dr Walter Willett: CardioNutrition – Why are findings from prospective, epidemiologic cohort studies important in informing dietary recommendations?

14 Oct, 2021 | 09:49h | UTC

ACC CardiaCast: CardioNutrition – Why Are Findings From Prospective, Epidemiologic Cohort Studies Important In Informing Dietary Recommendations? – American College of Cardiology

 

Commentary on Twitter

 

RCT: Oxytocin does not improve social functioning in children with autism spectrum disorder.

14 Oct, 2021 | 09:52h | UTC

News release: Oxytocin does not improve social functioning in children with autism spectrum disorder, NIH-funded study suggests – National Institutes of Health

Original study: Intranasal Oxytocin in Children and Adolescents with Autism Spectrum Disorder – New England Journal of Medicine

 

M-A: Outcomes after transcatheter aortic valve replacement in bicuspid versus tricuspid anatomy – device success and 1-year survival rates are similar, but patients with bicuspid valves have a higher risk for periprocedural complications.

14 Oct, 2021 | 09:51h | UTC

Outcomes After Transcatheter Aortic Valve Replacement in Bicuspid Versus Tricuspid Anatomy: A Systematic Review and Meta-Analysis – JACC: Cardiovascular Interventions

 

Survey finds patients undergoing medical imaging procedures have overall limited knowledge about medical radiation.

14 Oct, 2021 | 09:46h | UTC

Patient Perceptions and Knowledge of Ionizing Radiation From Medical Imaging – JAMA Network Open

Invited commentary: It Is Time to Inform Patients of Medical Imaging Risks – JAMA Network Open

 

Podcast: Acute Pain Management for the Hospitalist.

14 Oct, 2021 | 09:47h | UTC

#299 Acute Pain Management for the Hospitalist – The Curbsiders

 

Systematic Review: Music interventions may have beneficial effects on anxiety, depression, hope, pain, and fatigue in adults with cancer.

14 Oct, 2021 | 09:43h | UTC

Music interventions for improving psychological and physical outcomes in people with cancer – Cochrane Library

 

Systematic Review: Direct oral anticoagulants (DOACs) may be beneficial for people being treated for cancer who have no therapeutic or prophylactic indication for anticoagulation.

14 Oct, 2021 | 09:44h | UTC

Oral anticoagulation in people with cancer who have no therapeutic or prophylactic indication for anticoagulation – Cochrane Library

 

Systematic Review: Ultrasound guidance for arterial (other than femoral) catheterization in adults may improve first attempt and overall success rates compared to palpation.

14 Oct, 2021 | 09:41h | UTC

Ultrasound guidance for arterial (other than femoral) catheterisation in adults – Cochrane Library

 

WHO advisers recommend 3rd COVID vaccine dose for highest-risk groups.

13 Oct, 2021 | 01:48h | UTC

WHO advisers recommend 3rd COVID vaccine dose for highest-risk groups – CIDRAP

See also: WHO advises additional COVID shot for immunocompromised people – Reuters

 

Real-world data show that filters clean COVID-causing virus from air.

13 Oct, 2021 | 01:43h | UTC

Real-world data show that filters clean COVID-causing virus from air – Nature

Original article: The removal of airborne SARS-CoV-2 and other microbial bioaerosols by air filtration on COVID-19 surge units – medRxiv

 

Commentary on Twitter

 

Opinion | COVID lesson: trust the public with hard truths.

13 Oct, 2021 | 01:47h | UTC

COVID lesson: trust the public with hard truths – Nature

 

Commentary from the author on Twitter (thread – click for more)

 

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