All Posts | Links Medicus - Free Medical News & Perspective

State-of-the-art review of lung imaging in cystic fibrosis with recommendations for pulmonologists and radiologists.

1 Apr, 2022 | 08:19h | UTC

State-of-the-art review of lung imaging in cystic fibrosis with recommendations for pulmonologists and radiologists from the “iMAging managEment of cySTic fibROsis” (MAESTRO) consortium – European Respiratory Review

Practice review: Evidence-based management approaches for patients with severe chronic obstructive pulmonary disease (COPD).

1 Apr, 2022 | 08:29h | UTC

Evidence-based management approaches for patients with severe chronic obstructive pulmonary disease (COPD): A practice review – Palliative Medicine

Practice review: Evidence-based and effective management of fatigue in patients with advanced cancer.

1 Apr, 2022 | 08:26h | UTC

Practice review: Evidence-based and effective management of fatigue in patients with advanced cancer – Palliative Medicine

Review: The use of virtual care in patients with hematologic malignancies.

1 Apr, 2022 | 08:18h | UTC

The Use of Virtual Care in Patients with Hematologic Malignancies: A Scoping Review – Current Oncology

WHO Global genomic surveillance strategy for pathogens with pandemic and epidemic potential 2022–2032.

31 Mar, 2022 | 08:45h | UTC

Global genomic surveillance strategy for pathogens with pandemic and epidemic potential 2022–2032 – World Health Organization

News Release: WHO releases 10-year strategy for genomic surveillance of pathogens – World Health Organization

Commentary on Twitter (thread – click for more)

🆕 Today @WHO published the Global Genomic Surveillance Strategy for Pathogens with Pandemic and Epidemic Potential (2022–2032)

Ambitious, comprehensive, strategic and necessary.

Short thread ⬇️https://t.co/98NMgMhbL6

— Maria Van Kerkhove (@mvankerkhove) March 30, 2022

WHO recommendations on maternal and newborn care for a positive postnatal experience.

31 Mar, 2022 | 08:47h | UTC

WHO recommendations on maternal and newborn care for a positive postnatal experience – World Health Organization

News Release: WHO urges quality care for women and newborns in critical first weeks after childbirth – World Health Organization

Commentary: Postnatal care: WHO highlights urgency of physical and mental support – The BMJ

Study Commentary: Older women with breast cancer chose less aggressive treatment when they used a decision aid.

1 Apr, 2022 | 08:16h | UTC

Older women with breast cancer chose less aggressive treatment when they used a decision aid – National Institute for Health Research

Original Study: Bridging the age gap in breast cancer: cluster randomized trial of two decision support interventions for older women with operable breast cancer on quality of life, survival, decision quality, and treatment choices – British Journal of Surgery

Commentary on Twitter

Open access in May's BJS: Bridging the age gap in breast cancer: two decision support interventions for older women with operable breast cancer https://t.co/s70uEVyAxU @AmyLightnerMD @bplwijn @des_winter @ksoreide @MalinASund @evanscolorectal @nfmkok @robhinchliffe1 @young_bjs pic.twitter.com/IUuiUldUTS

— BJS (@BJSurgery) June 11, 2021

RCT: Early treatment with ivermectin does not improve outcomes in patients with Covid-19.

31 Mar, 2022 | 08:41h | UTC

Effect of Early Treatment with Ivermectin among Patients with Covid-19- New England Journal of Medicine

Commentary: Ivermectin does not prevent COVID-19 hospitalization, a new study says – NPR

Commentary on Twitter

Ivermectin: the largest randomized, double-blind trial yet conducted, with early treatment, indicates there is no difference compared with placebo. It doesn't work. Period. https://t.co/wiFygjRgkk
just published @NEJM pic.twitter.com/uZ0mMZnO0E

— Eric Topol (@EricTopol) March 30, 2022

RCT: Early outpatient treatment with convalescent plasma reduces the risk of hospitalization in patients with Covid-19.

31 Mar, 2022 | 08:39h | UTC

Early Outpatient Treatment for Covid-19 with Convalescent Plasma – New England Journal of Medicine

Commentaries:

Study finds convalescent plasma can be effective early COVID-19 therapy – Johns Hopkins University School of Medicine

Early Use of High-Titer Plasma Reduced COVID Hospitalizations— Randomized trial that influenced indication shows benefits in a mostly unvaccinated population – MedPage Today (free registration required)

Commentary on Twitter

https://twitter.com/NEJM/status/1509278140433981444

USPSTF Draft Recommendation Statement: the current evidence is insufficient to recommend screening for obstructive sleep apnea in asymptomatic individuals.

31 Mar, 2022 | 08:42h | UTC

Draft Recommendation Statement: Obstructive Sleep Apnea in Adults: Screening – US Preventive Services Task Force

Commentary: USPSTF: Evidence Lacking for OSA Screening in Asymptomatic Adults – HealthDay

RCT: Single-incision mini-slings for stress urinary incontinence in women.

31 Mar, 2022 | 08:35h | UTC

Single-Incision Mini-Slings for Stress Urinary Incontinence in Women – New England Journal of Medicine (link to abstract – $ for full-text)

Commentary: Single-incision mini-slings effective for stress urinary incontinence in women – Healio (free registration required)

Commentary on Twitter

For stress urinary incontinence in women, mini-slings were noninferior to midurethral slings with respect to patient-reported success at 15 months. https://t.co/Ag5p2u2WZW pic.twitter.com/PcajqXTiLW

— NEJM (@NEJM) March 30, 2022

Risk of SARS-CoV-2 reinfections in children: a prospective national surveillance study in England.

31 Mar, 2022 | 08:29h | UTC

Risk of SARS-CoV-2 reinfections in children: a prospective national surveillance study between January, 2020, and July, 2021, in England – The Lancet Child & Adolescent Health

Invited Commentary: Importance of understanding the reinfection risk of COVID-19 in children – The Lancet Child & Adolescent Health

Commentary on Twitter

Everything we know about #SARSCoV2 tells us that first infection reduces (but doesn’t eliminate) the risk & SEVERITY of further infections, even with new variants. Here is our paper showing this with delta reinfections in kids (work on omicron reinfections in progress)👇 https://t.co/3gDPBHRu18

— Shamez Ladhani (@ShamezLadhani) March 30, 2022

Meta-analysis of randomized trials: Clopidogrel is better than aspirin for the secondary prevention of cardiovascular events.

31 Mar, 2022 | 08:31h | UTC

P2Y₁₂ Inhibitor versus Aspirin Monotherapy for Secondary Prevention of Cardiovascular Events: Meta-Analysis of Randomized Trials – European Heart Journal Open

Commentary: Clopidogrel Superior to ‘Divine’ Aspirin Monotherapy in Secondary Prevention – TCTMD

Commentary on Twitter

Happy to share our paper in @ESC_Journals. In this meta-analysis of randomized trials, we found that as compared with aspirin, P2Y12i was associated with 11% and 19% reduction in MACE and MI respectively. https://t.co/Y3Gstzgfu6

— Devika Aggarwal (@devikagg) March 30, 2022

Case-control study: In children 5 to 11 years of age, the Pfizer vaccine showed an effectiveness of 68% against hospitalization caused by the Omicron variant.

31 Mar, 2022 | 08:37h | UTC

BNT162b2 Protection against the Omicron Variant in Children and Adolescents – New England Journal of Medicine

Commentary: COVID vaccination of children age 5-11 cut omicron hospitalizations by 68% – Children’s Hospital Boston

Commentary on Twitter

BNT162b2 vaccination reduced the risk of omicron-associated hospitalization by two thirds among children 5 to 11 years of age. https://t.co/mQcchQqbtH pic.twitter.com/Qzy8qKg1wC

— NEJM (@NEJM) March 30, 2022

M-A: Psychological interventions for chronic, non-specific low back pain.

31 Mar, 2022 | 08:20h | UTC

Psychological interventions for chronic, non-specific low back pain: systematic review with network meta-analysis – The BMJ

News Release: Study sheds light on psychological therapies for chronic low back pain – British Medical Journal

RCT: Effect of tacrolimus vs. intravenous cyclophosphamide on complete or partial response in patients with lupus nephritis.

31 Mar, 2022 | 08:18h | UTC

Effect of Tacrolimus vs Intravenous Cyclophosphamide on Complete or Partial Response in Patients With Lupus Nephritis: A Randomized Clinical Trial – JAMA Network Open

Commentary on Twitter

In this RCT, oral tacrolimus was noninferior to intravenous cyclophosphamide for initial therapy of active lupus nephritis, with a more favorable safety profile. https://t.co/scz7lahVRU

— JAMA Network Open (@JAMANetworkOpen) March 30, 2022

A Narrative Review on the approach to antimicrobial use in ventilated patients with multidrug resistant organisms in respiratory samples—to treat or not to treat?

31 Mar, 2022 | 08:27h | UTC

A Narrative Review on the Approach to Antimicrobial Use in Ventilated Patients with Multidrug Resistant Organisms in Respiratory Samples—To Treat or Not to Treat? That Is the Question – Antibiotics

Commentary on Twitter

https://twitter.com/ABsteward/status/1508917245740818438

Association of computed tomography screening with lung cancer stage shift and survival in the United States: quasi-experimental study.

31 Mar, 2022 | 08:23h | UTC

Association of computed tomography screening with lung cancer stage shift and survival in the United States: quasi-experimental study – The BMJ

Editorial: Screening high risk populations for lung cancer

News Release: US lung cancer screening linked to earlier diagnosis and better survival – British Medical Journal

Screening for Lung Cancer: CHEST Guideline and Expert Panel Report.

USPSTF Statement: begin screening for lung cancer at age 50 years instead of 55 years for patients at risk

Meta-analysis: Lung cancer screening using low-dose computed tomography reduces lung cancer–specific mortality, albeit with a tradeoff of likely overdiagnosis

Commentary on Twitter

Increases in the early detection of lung cancer since 2014 in the US have saved an estimated 10,100 lives, but screening rates are still extremely low and disparities in access to lung cancer screening continue to exist, say researchers https://t.co/j58LfcGCKU

— The BMJ (@bmj_latest) March 31, 2022