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Safety of ezetimibe in lipid-lowering treatment: systematic review and meta-analysis of randomized controlled trials and cohort studies.

6 May, 2022 | 10:59h | UTC

Safety of ezetimibe in lipid-lowering treatment: systematic review and meta-analysis of randomised controlled trials and cohort studies – BMJ Medicine

PCSK9 inhibitors and ezetimibe for the reduction of cardiovascular events: a clinical practice guideline with risk-stratified recommendations – The BMJ

PCSK9 inhibitors and ezetimibe with or without statin therapy for cardiovascular risk reduction: a systematic review and network meta-analysis – The BMJ

Commentary on Twitter

Read a new #systematicreview and meta-analysis of RCTs and cohort studies on the safety of #Ezetimibe in lipid-lowering treatment. ▶️ https://t.co/mr4H5MfVdP #VisualAbstract #RapidRecommendations @bmj_latest @theMAGICapp pic.twitter.com/OLg0HZr8D3

— BMJMedicine (@BMJMedicine) May 5, 2022

Long COVID: aiming for a consensus.

6 May, 2022 | 11:03h | UTC

Long COVID: aiming for a consensus – The Lancet Respiratory Medicine

Commentary on Twitter

There is an urgent need for unification of terminology for the sequelae of #SARSCoV2 infection to ensure that research is directed towards and translated into interventional trials to improve outcomes

NEW Comment—#LongCOVID: aiming for a consensushttps://t.co/dZO4rBVCSY pic.twitter.com/H5ezqL0RLb

— The Lancet Respiratory Medicine (@LancetRespirMed) May 5, 2022

Position statement on acute oxygen use in adults: ‘swimming between the flags’.

6 May, 2022 | 10:56h | UTC

Thoracic Society of Australia and New Zealand Position Statement on Acute Oxygen Use in Adults: ‘Swimming between the flags’ – Respirology

Long-term mortality and health-related quality of life of lower versus higher oxygenation targets in ICU patients with severe hypoxaemia – Intensive Care Medicine

Oxygen Targets During Mechanical Ventilation in the ICU: A Systematic Review and Meta-Analysis – Critical Care Explorations

Effect of Low-Normal vs High-Normal Oxygenation Targets on Organ Dysfunction in Critically Ill Patients: A Randomized Clinical Trial – JAMA

Lower or Higher Oxygenation Targets for Acute Hypoxemic Respiratory Failure – New England Journal of Medicine

Guideline Summary: New guidance on the perioperative management of diabetes.

6 May, 2022 | 10:55h | UTC

New guidance on the perioperative management of diabetes – Clinical Medicine Journal

Original Guideline: Perioperative Care of People with Diabetes Undergoing Surgery

Perioperative Evaluation and Management of Endocrine Disorders – Mayo Clinic Proceedings

Recent advances in diabetes treatments and their perioperative implications – Current Opinion in Anesthesiology

Perioperative Management of Oral Glucose-lowering Drugs in the Patient with Type 2 Diabetes – Anesthesiology

Intravenous contrast medium extravasation: systematic review and updated ESUR Contrast Media Safety Committee Guidelines.

6 May, 2022 | 10:53h | UTC

Intravenous contrast medium extravasation: systematic review and updated ESUR Contrast Media Safety Committee Guidelines – European Radiology

A Canadian national guideline on the neoadjuvant treatment of invasive breast cancer, including patient assessment, systemic therapy, and local management principles.

6 May, 2022 | 10:52h | UTC

A Canadian national guideline on the neoadjuvant treatment of invasive breast cancer, including patient assessment, systemic therapy, and local management principles – Breast Cancer Research and Treatment

Left ventricular remodeling post-myocardial infarction: pathophysiology, imaging, and novel therapies.

6 May, 2022 | 10:50h | UTC

Left ventricular remodelling post-myocardial infarction: pathophysiology, imaging, and novel therapies – European Heart Journal

Systematic Review: Cannabis and cannabinoids for symptomatic treatment for people with multiple sclerosis.

6 May, 2022 | 10:47h | UTC

Cannabis and cannabinoids for symptomatic treatment for people with multiple sclerosis – Cochrane Library

Summary: Cannabis and cannabinoids for people with multiple sclerosis – Cochrane Library

Commentary on Twitter

💚A UK survey found that 1 in 5 people with #MS reported they used #Cannabis to manage symptoms.
🤔 Does it work? Are there harms?
📚 Cochrane systematic review looks at 25 RCTs ➡️ https://t.co/HCt6Cx3suo #MedicalMarijuana #MultipleSclerosis pic.twitter.com/wjDTXXEciM

— The Cochrane Library (@CochraneLibrary) May 5, 2022

M-A: Wearable cuffless blood pressure monitoring devices.

6 May, 2022 | 10:48h | UTC

Wearable Cuffless Blood Pressure Monitoring Devices: A Systematic Review and Meta-Analysis – European Heart Journal – Digital Health

Commentary on Twitter

Wearable cuffless blood pressure monitoring devices: a systematic review and meta-analysis https://t.co/UP2M81OuzB #EHJDigital @BruiningNico @rafavidalperez @pauldub67 @clara_chow pic.twitter.com/8ouQvSH8mQ

— European Society of Cardiology Journals (@ESC_Journals) May 4, 2022

Systematic Review: Clinical practice guideline recommendations on tapering and discontinuing antidepressants for depression.

6 May, 2022 | 10:37h | UTC

Clinical practice guideline recommendations on tapering and discontinuing antidepressants for depression: a systematic review – Therapeutic Advances in Psychopharmacology

Discontinuing antidepressants: Pearls and pitfalls.

Review | Newer generation antidepressants and withdrawal effects: reconsidering the role of antidepressants and helping patients to stop.

RCT: Maintenance vs. discontinuation of antidepressants in patients who felt well enough to discontinue antidepressant therapy.

A method for tapering antipsychotic treatment that may minimize the risk of relapse

Systematic Review: Managing Antidepressant Discontinuation

Randomized controlled trial: preventive cognitive therapy for prevention of depressive recurrence

M-A: Continuation of antidepressants vs. sequential psychological interventions to prevent relapse in depression.

Global inequalities in the double burden of malnutrition and associations with globalization: a multilevel analysis of Demographic and Healthy Surveys from 55 low-income and middle-income countries, 1992–2018.

6 May, 2022 | 10:38h | UTC

Global inequalities in the double burden of malnutrition and associations with globalisation: a multilevel analysis of Demographic and Healthy Surveys from 55 low-income and middle-income countries, 1992–2018 – The Lancet Global Health

Commentary: Associations between country-level macroeconomic factors and the double burden of malnutrition – The Lancet Global Health

Commentary from the author on Twitter (thread – click for more)

https://twitter.com/e_seferidi/status/1491354228581105665

Giving people money with no strings attached is good for their health, dozens of studies indicate.

6 May, 2022 | 10:44h | UTC

Giving people money with no strings attached is good for their health, dozens of studies indicate – The Conversation

Review: Pharmacologic management of persistent pain in cancer survivors.

6 May, 2022 | 10:34h | UTC

Pharmacologic Management of Persistent Pain in Cancer Survivors – Drugs

Review: Overcoming Stenotrophomonas maltophilia resistance for a more rational therapeutic approach.

6 May, 2022 | 10:31h | UTC

Overcoming Stenotrophomonas maltophilia Resistance for a More Rational Therapeutic Approach – Open Forum Infectious Diseases

Review: Non-invasive testing and surrogate markers in invasive fungal diseases.

6 May, 2022 | 10:29h | UTC

Non-invasive Testing and Surrogate Markers in Invasive Fungal Diseases – Open Forum Infectious Diseases

Is Artificial Intelligence (AI) a pipe dream? Why legal issues present significant hurdles to ai autonomy.

6 May, 2022 | 10:32h | UTC

Is Artificial Intelligence (AI) a Pipe Dream? Why Legal Issues Present Significant Hurdles to AI Autonomy – American Journal of Radiology

First-line salvage treatment options for germ cell tumor patients failing stage-adapted primary treatment.

6 May, 2022 | 10:27h | UTC

First-line salvage treatment options for germ cell tumor patients failing stage-adapted primary treatment – World Journal of Urology

M-A: Body position for preventing ventilator-associated pneumonia for critically ill patients.

6 May, 2022 | 10:23h | UTC

Body position for preventing ventilator-associated pneumonia for critically ill patients: a systematic review and network meta-analysis – Journal of Intensive Care

Mobile phone-based interventions for mental health: A systematic meta-review of 14 meta-analyses of randomized controlled trials.

6 May, 2022 | 10:25h | UTC

Mobile phone-based interventions for mental health: A systematic meta-review of 14 meta-analyses of randomized controlled trials – PLOS Digital Health

Review: Outcomes of Enhanced Recovery after Surgery (ERAS) in gynecologic oncology.

6 May, 2022 | 10:22h | UTC

Outcomes of Enhanced Recovery after Surgery (ERAS) in Gynecologic Oncology: A Review – Current Oncology

Review: Advances in radiation oncology for the treatment of cervical cancer.

6 May, 2022 | 10:20h | UTC

Advances in Radiation Oncology for the Treatment of Cervical Cancer – Current Oncology

Perspective | Does glycemic index matter for weight loss and obesity prevention? Examination of the evidence on “fast” compared with “slow” carbs.

6 May, 2022 | 10:19h | UTC

Perspective: Does Glycemic Index Matter for Weight Loss and Obesity Prevention? Examination of the Evidence on “Fast” Compared with “Slow” Carbs – Advances in Nutrition

Ten tips to optimize vasopressors use in the critically ill patient with hypotension.

5 May, 2022 | 11:07h | UTC

Ten tips to optimize vasopressors use in the critically ill patient with hypotension – Intensive Care Medicine (if the link is paywalled, try this one)

Commentary on Twitter

Vasopressors in #ICU
1️⃣set MAP/DBP goals
2️⃣individualize
3️⃣may⬇️+ve fluid balance
4️⃣reassess fluid status/CO
5️⃣change mechanism as 2 line
6️⃣high doses?? hydrocortisone
7️⃣vasopressin in RV failure
8️⃣no MAX dose
9️⃣EN can be initiated
🔟can be safe in PVC
🖇 https://t.co/v6Q9nfy5KY pic.twitter.com/8YEDaOQBOQ

— Intensive Care Medicine (@yourICM) May 4, 2022