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Review: Comfort during non-invasive ventilation.

12 May, 2022 | 08:07h | UTC

Comfort During Non-invasive Ventilation – Frontiers in Medicine

Nonregistration, discontinuation, and nonpublication of randomized trials: A repeated metaresearch analysis.

12 May, 2022 | 08:08h | UTC

Nonregistration, discontinuation, and nonpublication of randomized trials: A repeated metaresearch analysis – PLOS Medicine

Review: Mucus clearance strategies in mechanically ventilated patients.

12 May, 2022 | 08:06h | UTC

Mucus Clearance Strategies in Mechanically Ventilated Patients – Frontiers in Physiology

M-A: Evaluation of HIV treatment outcomes with reduced frequency of clinical encounters and antiretroviral treatment refills.

12 May, 2022 | 08:04h | UTC

Evaluation of HIV treatment outcomes with reduced frequency of clinical encounters and antiretroviral treatment refills: A systematic review and meta-analysis – PLOS Medicine

M-A: Effectiveness of physiotherapy interventions for back care and the prevention of non-specific low back pain in children and adolescents.

12 May, 2022 | 08:02h | UTC

Effectiveness of physiotherapy interventions for back care and the prevention of non-specific low back pain in children and adolescents: a systematic review and meta-analysis – BMC Musculoskeletal Disorders

Commentary on Twitter

Research published in #BMCMusculoSkeletDisord reports that physical exercise, postural hygiene and physical activity are the most effective preventive physiotherapy interventions to improve back care and prevent low back pain in children and adolescents. https://t.co/YEb3xxDHVD

— BMC (@BioMedCentral) April 16, 2022

M-A: Comparative impact of pharmacological therapies on cluster headache management.

12 May, 2022 | 08:01h | UTC

Comparative Impact of Pharmacological Therapies on Cluster Headache Management: A Systematic Review and Network Meta-Analysis – Journal of Clinical Medicine

M-A: More evidence on cash transfers and child nutritional outcomes.

12 May, 2022 | 07:59h | UTC

More evidence on cash transfers and child nutritional outcomes: a systematic review and meta-analysis – BMJ Global Health

Commentary on Twitter

https://twitter.com/Ugentilini/status/1509943611181441031

Interstitial lung disease in infancy and early childhood: a clinicopathological primer.

12 May, 2022 | 07:54h | UTC

Interstitial lung disease in infancy and early childhood: a clinicopathological primer – European Respiratory Review

M-A: Systemic immunomodulatory treatments for atopic dermatitis.

12 May, 2022 | 07:56h | UTC

Systemic Immunomodulatory Treatments for Atopic Dermatitis: Update of a Living Systematic Review and Network Meta-analysis – JAMA Dermatology

Commentary: Living review compares treatments for atopic dermatitis – HealthDay

Commentary on Twitter:

This systematic review and meta-analysis provides up-to-date comparative evidence of new and old systemic treatments for atopic dermatitis, like biologics and JAK inhibitors. https://t.co/ihqQWlihc7 @aaron_drucker

— JAMA Dermatology (@JAMADerm) March 16, 2022

Endometrial scratch to increase live birth rates in women undergoing first-time in vitro fertilization: RCT and systematic review.

12 May, 2022 | 07:53h | UTC

Endometrial scratch to increase live birth rates in women undergoing first-time in vitro fertilisation: RCT and systematic review – Health Technology Assessment

Survey: Despite insufficient evidence of benefit, many fertility specialists still perform endometrial scratching before in vitro fertilization.

Endometrial scratching: what’s the latest evidence? – “we are uncertain whether endometrial injury has an effect on the probability of getting pregnant and having a baby”.

A Randomized Trial of Endometrial Scratching before In Vitro Fertilization – New England Journal of Medicine

M-A: Chemoradiotherapy followed by active surveillance vs. standard esophagectomy for esophageal cancer.

12 May, 2022 | 07:51h | UTC

Chemoradiotherapy Followed by Active Surveillance Versus Standard Esophagectomy for Esophageal Cancer: A Systematic Review and Individual Patient Data Meta-analysis – Annals of Surgery (link to abstract – $ for full-text)

Systematic Review: Prevention of peripheral distal polyneuropathy in patients with diabetes.

12 May, 2022 | 07:58h | UTC

Prevention of Peripheral Distal Polyneuropathy in Patients with Diabetes: A Systematic Review – Journal of Clinical Medicine

RCT: Early vs. expectant artificial rupture of membranes following Foley catheter ripening.

12 May, 2022 | 07:50h | UTC

Early vs expectant artificial rupture of membranes following Foley catheter ripening: a randomized controlled trial – American Journal of Obstetrics & Gynecology (link to abstract – $ for full-text)

Commentary on Twitter

Early vs expectant artificial rupture of membranes following Foley catheter ripening: a randomized controlled trial #SMFM22 https://t.co/BqQ7024Rvs pic.twitter.com/9wvE8ii1ES

— AJOG (@AJOG_thegray) February 28, 2022

USPSTF recommends against screening for COPD in asymptomatic adults.

11 May, 2022 | 11:26h | UTC

Screening for Chronic Obstructive Pulmonary Disease: US Preventive Services Task Force Reaffirmation Recommendation Statement – JAMA

Editorial: Screening for Chronic Obstructive Pulmonary Disease: Challenges and Opportunities – JAMA

Evidence Report: Screening for Chronic Obstructive Pulmonary Disease: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force – JAMA

Patient Page: Screening for Chronic Obstructive Pulmonary Disease – JAMA

Author Interview: USPSTF Recommendation: Screening for Chronic Obstructive Pulmonary Disease – JAMA

Commentary: USPSTF Continues to Recommend Against COPD Screening in Asymptomatic Adults – AJMC

Commentary on Twitter

The 🇺🇸 USPSTF, again, recommends against screening for #COPD jn asymptomatic adults: ‘using a reaffirmation process, the USPSTF concludes with moderate certainty that screening for COPD in asymptomatic adults has no net benefit’. https://t.co/msBtDBKngx

— John Hurst (@ProfHurst) May 10, 2022

Use of novel strategies to develop guidelines for management of pyogenic osteomyelitis in adults: a WikiGuidelines group consensus statement.

11 May, 2022 | 11:23h | UTC

Use of Novel Strategies to Develop Guidelines for Management of Pyogenic Osteomyelitis in Adults: A WikiGuidelines Group Consensus Statement – JAMA Network Open

Commentary: A new approach to medical guidelines, taking inspiration from Wikipedia – University of Michigan

Commentary on Twitter

This consensus statement & systematic review uses a WikiGuidelines methodology for clinical guideline development (precluding recommendations based on low-quality data/opinion), addressing 7 questions regarding osteomyelitis management. @BradSpellberg https://t.co/MVjkzC5rdf

— JAMA Network Open (@JAMANetworkOpen) May 10, 2022

Study suggests tailoring diabetes screening by race and ethnicity may lead to earlier diagnosis.

11 May, 2022 | 11:19h | UTC

Commentary: Tailoring diabetes screening by race, ethnicity may lead to earlier diagnosis – ACP Internist

News Release: Screening Some Sooner May Reduce Racial and Ethnic Disparities in Diabetes Diagnosis, Researchers Show – Beth Israel Deaconess Medical Center

Original Study: Diabetes Screening by Race and Ethnicity in the United States: Equivalent Body Mass Index and Age Thresholds – Annals of Internal Medicine (link to abstract – $ for full-text)

Commentary from the author on Twitter (thread – click for more)

1/In her 40s, my mother, an Indian American, was diagnosed with diabetes, though she was not indicated for screening

This led me to ask…do we appropriately screen for diabetes by race/ethnicity?

Now answered in @AnnalsofIM with⭐️mentor @kardiologykazi https://t.co/xTM9WmIbaL pic.twitter.com/IK5v76KMxh

— Rahul Aggarwal (@RahulAggarwalMD) May 9, 2022

AHA: Call to action for cardiovascular disease in women: epidemiology, awareness, access, and delivery of equitable health care.

11 May, 2022 | 11:22h | UTC

Call to Action for Cardiovascular Disease in Women: Epidemiology, Awareness, Access, and Delivery of Equitable Health Care: A Presidential Advisory From the American Heart Association – Circulation

News Release: Investment, action urged to improve access, quality and equity in women’s heart health – American Heart Association

Phase 2 RCT: A fourth dose of an mRNA Covid-19 vaccine increases cellular and humoral immunity against SARS-CoV-2.

11 May, 2022 | 11:14h | UTC

Safety, immunogenicity, and reactogenicity of BNT162b2 and mRNA-1273 COVID-19 vaccines given as fourth-dose boosters following two doses of ChAdOx1 nCoV-19 or BNT162b2 and a third dose of BNT162b2 (COV-BOOST): a multicentre, blinded, phase 2, randomised trial – The Lancet Infectious Diseases

Commentaries:

What a second booster dose of mRNA COVID-19 vaccines tells us – The Lancet Infectious Diseases

Covid: Fourth-dose jab trial shows good boost – BBC

Commentary on Twitter (thread – click for more)

The results of the @CovBoost fourth dose booster substudy are now online in @TheLancetInfDis

We demonstrated fourth doses of covid vaccines were safe and well tolerated and boost antibody levels above their peak following a third dosehttps://t.co/zGi0iNCAcL

— Alasdair Munro (@apsmunro) May 10, 2022