All Posts
RCT: Apixaban is not superior to the standard of care (vitamin K antagonist or antiplatelet therapy if anticoagulation is indicated or not, respectively) after transcatheter aortic valve implantation.
20 May, 2022 | 10:59h | UTCApixaban vs. standard of care after transcatheter aortic valve implantation: the ATLANTIS trial – European Heart Journal (link to abstract – $ for full-text)
Related:
Variation in the estimated prevalence of multimorbidity: systematic review and meta-analysis of 193 international studies.
20 May, 2022 | 10:58h | UTC
Commentary on Twitter
Our meta-analysis led by Iris Szu-Szu & Bruce Guthrie
Prevalence of multimorbidity = 42.4%
No difference in prevalence between low-income or middle-income countries
Future studies should use a common core conditions to improve comparabilityhttps://t.co/FdjJ2P4dtN pic.twitter.com/DP3IeWI5sR
— Prof Kamlesh Khunti (@kamleshkhunti) May 19, 2022
RCT: Elacestrant (oral selective estrogen receptor degrader) vs. standard endocrine therapy for estrogen receptor–positive, human epidermal growth factor receptor 2–negative advanced breast cancer.
20 May, 2022 | 10:55h | UTC
M-A: Comparison of Amitriptyline with other FDA–approved treatments for fibromyalgia.
20 May, 2022 | 10:49h | UTC
M-A: Management of asymptomatic severe aortic stenosis.
20 May, 2022 | 10:54h | UTCManagement of asymptomatic severe aortic stenosis: a systematic review and meta-analysis – openheart
Commentaries on Twitter
Management of asymptomatic severe aortic stenosis: a systematic review and meta-analysis @justvick @vass_vassiliou @MarcDweck @jhfrudd https://t.co/eFJbT3AiPn pic.twitter.com/g2GwKvlODW
— Open Heart (@Open_HeartBMJ) May 18, 2022
Our latest work led by #WIC @justvick on earlier surgery in asymptomatic aortic stenosis @Open_HeartBMJ inc all RCT & observational studies – huge suggestion that ‘earlier the better!’ https://t.co/u56LffOjAD great collaboration with @MarcDweck @jhfrudd @HEARTinMagnet #epeeps pic.twitter.com/WlKn1e6c9S
— Vass Vassiliou (@vass_vassiliou) May 18, 2022
Age distribution of all-cause mortality among children younger than 5 years in low- and middle-income countries.
20 May, 2022 | 10:46h | UTC
Association of extreme heat with all-cause mortality in the contiguous US, 2008-2017.
20 May, 2022 | 10:48h | UTC
Commentary on Twitter
1/ Out now in @JAMANetworkOpen. @petegroen
@rm_werner and I demonstrate the association between extreme heat days and all-cause mortality across the contiguous US.@PennLDI https://t.co/s6rPMN7qUD— Sameed Khatana, MD MPH (@SameedKhatana) May 19, 2022
Systematic Review: Landscaping the evidence of intimate partner violence and postpartum depression.
20 May, 2022 | 10:44h | UTC
RCT: Tenecteplase vs. alteplase for the management of acute ischemic stroke.
20 May, 2022 | 10:43h | UTCTenecteplase versus alteplase for the management of acute ischaemic stroke in Norway (NOR-TEST 2, part A): a phase 3, randomised, open-label, blinded endpoint, non-inferiority trial – The Lancet Neurology (link to abstract – $ for full-text)
Hemoperfusion: technical aspects and state of the art.
20 May, 2022 | 10:41h | UTCHemoperfusion: technical aspects and state of the art – Critical Care
Routine use of indirect calorimetry in critically ill patients: pros and cons.
20 May, 2022 | 10:39h | UTCRoutine use of indirect calorimetry in critically ill patients: pros and cons – Critical Care
Overview of complications in cirrhosis.
20 May, 2022 | 10:37h | UTCOverview of Complications in Cirrhosis – Journal of Clinical and Experimental Hepatology
Review: Management of refractory variceal bleed in cirrhosis.
20 May, 2022 | 10:36h | UTC
Systematic Review | Post-stroke dysphagia: prognosis and treatment.
20 May, 2022 | 10:33h | UTC
Systematic Review: Percutaneous transluminal angioplasty and stenting for vertebral artery stenosis.
20 May, 2022 | 10:28h | UTCPercutaneous transluminal angioplasty and stenting for vertebral artery stenosis – Cochrane Library
Summary: Endovascular treatment for vertebral artery stenosis – Cochrane Library
Systematic Review: Antibiotics for the induction and maintenance of remission in ulcerative colitis.
20 May, 2022 | 10:29h | UTCAntibiotics for the induction and maintenance of remission in ulcerative colitis – Cochrane Library
Summary: The use of antibiotics in the treatment of ulcerative colitis – Cochrane Library
Network meta-analysis of different intravenous glucocorticoid regimes for the treatment of Graves’ orbitopathy.
20 May, 2022 | 10:34h | UTC
Systematic Review: Immediate versus delayed postabortion insertion of contraceptive implant.
20 May, 2022 | 10:26h | UTCImmediate versus delayed postabortal insertion of contraceptive implant – Cochrane Library
Systematic Review: Pain management for medical abortion before 14 weeks’ gestation.
20 May, 2022 | 10:25h | UTCPain management for medical abortion before 14 weeks’ gestation – Cochrane Library
Summary: Pain management for medical abortion before 14 weeks’ gestation – Cochrane Library
UK, Spain, Portugal report more monkeypox cases.
19 May, 2022 | 11:15h | UTCUK, Spain, Portugal report more monkeypox cases – CIDRAP
See also:
U.S. monkeypox case reported, as Spain, Portugal report infections in growing outbreak – STAT
Monkeypox – United Kingdom of Great Britain and Northern Ireland – World Health Organization
Monkeypox cases confirmed in England – latest updates – UK Health Security Agency
Seven Confirmed Monkeypox Cases in UK Includes Sexually Transmitted Cluster – Health Policy Watch
European outbreak of monkeypox: what you need to know – The Conversation
Rare monkeypox outbreak in U.K., Europe and U.S.: What is it and should we worry – NPR
Monkeypox cases under investigation in Canada as outbreak spreads in Europe, U.S. – CBC News
Commentary on Twitter
On the rare monkeypox outbreak in Europe!
Health officials have little clue where people caught the virus. And there's concern the virus may be spreading through the community – undetected – and possibly through a new route of transmission #IDTwitter https://t.co/KOQ8rM2nW9— Antibiotic Steward Bassam Ghanem 🅱️C🆔🅿️🌟 (@ABsteward) May 18, 2022
Pollution and health: a progress update.
19 May, 2022 | 11:12h | UTCPollution and health: a progress update – The Lancet Planetary Health
Commentaries:
One in six killed by pollution worldwide, study finds – CNN
Pollution responsible for one in six deaths across planet, scientists warn – The Guardian
Commentary on Twitter
Pollution resulted in more than 9 million deaths and major losses in economic output in 2019, and there’s been little progress since 2015. Read more in the new update to the Lancet Commission on pollution and health. #SolvePollution #PollutionCommissionhttps://t.co/JQqCiS9s2e pic.twitter.com/hNoePKtRew
— The Lancet Planetary Health (@TheLancetPlanet) May 18, 2022
The pandemic’s true health cost: how much of our lives has COVID stolen?
19 May, 2022 | 11:09h | UTCThe pandemic’s true health cost: how much of our lives has COVID stolen? – Nature
Commentary on Twitter
What's missed by our fixation on hospitalization and death metrics for the pandemic—the disability toll—the impact by disability-adjusted life years (DALYs) https://t.co/dFWNuVah3z@HollyElse @Nature #LongCovid pic.twitter.com/Fql0a4ObLH
— Eric Topol (@EricTopol) May 18, 2022
Discovery reveals blocking inflammation may lead to chronic pain.
19 May, 2022 | 11:06h | UTCNews Release: Discovery reveals blocking inflammation may lead to chronic pain – McGill University
Original Study: Acute inflammatory response via neutrophil activation protects against the development of chronic pain – Science Translational Medicine
Commentary on Twitter
Challenging medical dogma:
A very important new report suggests that non-steroidal inflammatory medications for acute pain can lead to chronic painhttps://t.co/Z8yjFFBCkK @ScienceTM https://t.co/YGjkXbvNTa pic.twitter.com/f4xVezAhau— Eric Topol (@EricTopol) May 18, 2022
Results of two cases of pig-to-human kidney xenotransplantation.
19 May, 2022 | 11:11h | UTCResults of Two Cases of Pig-to-Human Kidney Xenotransplantation – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary on Twitter
Genetically modified pig kidney xenografts were transplanted into two brain-dead human recipients. The xenografts functioned immediately, showed no evidence of acute rejection over a period of 54 hours. https://t.co/gWlpX1dCTC pic.twitter.com/Zp5XdA4QH5
— NEJM (@NEJM) May 18, 2022
Opinion | Does Paxlovid help people who have been vaccinated against Covid-19? Show us the data!
19 May, 2022 | 11:07h | UTCDoes Paxlovid help people who have been vaccinated against Covid-19? Show us the data! – STAT