All Posts
Systematic Review: Prophylactic antiemetics for adults receiving intravenous opioids in the acute care setting.
23 May, 2022 | 01:29h | UTC
Drugs for agitation in people with dementia: benefits and risks.
23 May, 2022 | 01:25h | UTCDrugs for agitation in people with dementia: benefits and risks – Evidently Cochrane
Original Study: Antipsychotics for agitation and psychosis in people with Alzheimer’s disease and vascular dementia – Cochrane Library
Commentary on Twitter (thread – click for more)
https://twitter.com/CochraneUK/status/1527579340350935045
Preventing dementia: what’s the evidence?
23 May, 2022 | 01:27h | UTCPreventing dementia: what’s the evidence? – Evidently Cochrane
Cohort Study: Association of thyroid hormone treatment intensity with cardiovascular mortality.
23 May, 2022 | 01:23h | UTCCommentaries:
Thyroid Hormone Treatment Intensity and Cardiovascular Mortality – American College of Cardiology
Thyroid Hormone Treatment Intensity May Be Modifiable Risk Factor for CV Mortality – HCP Live
Commentary on Twitter
In this cohort study of US Veterans on thyroid hormone therapy, both exogenous hyperthyroidism and hypothyroidism contributed to the increased risk of cardiovascular mortality after adjusting for demographic and traditional cardiovascular risk factors. https://t.co/NO4776Ia4m
— JAMA Network Open (@JAMANetworkOpen) May 12, 2022
12 plagues of AI in healthcare: a practical guide to current issues with using machine learning in a medical context.
23 May, 2022 | 01:21h | UTC
Definitions and standardized endpoints for treatment of coronary bifurcations.
23 May, 2022 | 01:18h | UTCDefinitions and Standardized Endpoints for Treatment of Coronary Bifurcations – EuroIntervention
Commentary on Twitter
https://twitter.com/DFCapodanno/status/1526917363311968257
QRS micro-fragmentation as a mortality predictor.
23 May, 2022 | 01:19h | UTCQRS micro-fragmentation as a mortality predictor – European Heart Journal
Editorial: The fractionated QRS complex for cardiovascular risk assessment – European Heart Journal
Commentary on Twitter
QRS micro-fragmentation as a mortality predictor: discover more in EHJ! https://t.co/P0gkPFpIs8#EKG #QRS #fragmentation #prediction #outcome #cardiotwitter @escardio @ESC_Journals pic.twitter.com/8IAIL3fXFF
— EHJ Editor-in-Chief (@ehj_ed) February 22, 2022
Under a https://creativecommons.org/licenses/by/4.0/ license
Observational study suggests hepatic arterial infusion pump chemotherapy may be an alternative to resection for patients with multifocal intrahepatic cholangiocarcinoma.
23 May, 2022 | 00:52h | UTCComparison of Hepatic Arterial Infusion Pump Chemotherapy vs Resection for Patients With Multifocal Intrahepatic Cholangiocarcinoma – JAMA Surgery (link to abstract – $ for full-text)
Commentaries:
Treating iCCA With Chemo Pump Can Be as Effective as Surgery, JAMA Study Finds – AJMC
Commentaries on Twitter
https://twitter.com/JAMASurgery/status/1524872044827000836
https://twitter.com/SyedAAhmad5/status/1527034049721663489
Feasibility of whole genome and transcriptome profiling in pediatric and young adult cancers.
23 May, 2022 | 01:16h | UTCCommentaries:
Commentary from the author on Twitter (thread – click for more)
Feasibility of clinical whole genome and transcriptome sequencing (WGTS) in oncology. A 🧵 on our latest study published in Nature Communications today:https://t.co/6007GkYDAc
— Elli Papaemmanuil, PhD (@PapaemmanuilLab) May 18, 2022
Viewpoint: The imperative for diversity and inclusion in clinical trials and health research participation.
23 May, 2022 | 00:49h | UTC
Review: Tympanostomy tubes for children with acute otitis media.
23 May, 2022 | 00:46h | UTCTympanostomy tubes for children with acute otitis media – Canadian Family Physician
Cohort Study: Clinical features and natural history of preadolescent nonsyndromic hypertrophic cardiomyopathy.
23 May, 2022 | 00:45h | UTCCommentary: Clinical Features and Course of Preadolescent Hypertrophic Cardiomyopathy – American College of Cardiology
Review: Allergic asthma is a risk factor for human cardiovascular diseases.
23 May, 2022 | 00:48h | UTCAllergic asthma is a risk factor for human cardiovascular diseases – Nature Cardiovascular Research
Commentary on Twitter
A Review in @NatureCVR discusses how asthma and allied allergic conditions may contribute to the prevalence, incidence and progression of cardiovascular diseases and vice versa. https://t.co/6kRj9LvOfa pic.twitter.com/Ydq8X2k1rY
— Nature Portfolio (@NaturePortfolio) May 18, 2022
Low-flow acute kidney injury: the pathophysiology of prerenal azotemia, abdominal compartment syndrome, and obstructive uropathy.
23 May, 2022 | 00:43h | UTC
Identification of high-risk multiple myeloma with a plasma cell leukemia-like transcriptomic profile.
23 May, 2022 | 00:41h | UTC
Commentary on Twitter
A transcriptomic primary plasma cell leukaemia classifier comprising 53 genes had a sensitivity of 93% in pts with newly-diagnosed MM. Multivariate analysis confirmed the prognostic performance of this classifier vs the International Staging System: https://t.co/bD45PQG9bl #MMSM
— NatureRevClinOncol (@NatRevClinOncol) April 7, 2022
Cohort Study: Effect of awake craniotomy in glioblastoma in eloquent areas.
23 May, 2022 | 00:40h | UTCEffect of awake craniotomy in glioblastoma in eloquent areas (GLIOMAP): a propensity score-matched analysis of an international, multicentre, cohort study – the Lancet Oncology (link to abstract – $ for full-text)
Commentary: Neurologic and Survival Outcomes After Awake Craniotomy for Glioblastoma – The ASCO Post
Commentary on Twitter
In matched cohort of patients with glioblastoma, awake craniotomy resulted in fewer neurological deficits at 3 mo and 6 mo post-surgery than asleep resection, and longer mOS (17.0 mo versus 14.0 mo; P =0.0005), and mPFS (9.0 mo versus 7.3 mo; P = 0.006) https://t.co/S1fdRTxYDg
— NatureRevClinOncol (@NatRevClinOncol) May 19, 2022
AHA Scientific Statement: Preventing and managing falls in adults with cardiovascular disease.
20 May, 2022 | 11:20h | UTCNews Release: Statement addresses ways to prevent heart-related risks for falling – American Heart Association
Commentary: AHA News: Falls Can Be a Serious, Poorly Understood Threat to People With Heart Disease – HealthDay
WHO: 2022 Progress report on the Global Action Plan for Healthy Lives and Well-being for All.
20 May, 2022 | 11:17h | UTC
Commentary on Twitter (thread – click for more)
Progress on the health-related SDGs is further off track – countries have achieved only about one-fourth of what is needed to achieve the SDG health targets by 2030: Global Action Plan for Healthy Lives & Well-being for All #SDG3GAP progress report.
More https://t.co/HF8LO5UbVo pic.twitter.com/kGXoMTHnnh
— World Health Organization (WHO) (@WHO) May 18, 2022
WHO validates 11th vaccine for COVID-19.
20 May, 2022 | 11:16h | UTCWHO validates 11th vaccine for COVID-19 – World Health Organization
Commentary on Twitter
WHO issued an emergency use listing for CONVIDECIA, a vaccine manufactured by CanSino Biologics, China, adding to a growing portfolio of #COVID19 vaccines validated by WHO https://t.co/QdpHiasT2p pic.twitter.com/2B54FwiNDl
— World Health Organization (WHO) (@WHO) May 19, 2022
Covid-19: Second boosters may benefit at-risk groups but have “minimal” impact for others, says WHO.
20 May, 2022 | 11:08h | UTCOriginal Statement: Interim statement on the use of additional booster doses of Emergency Use Listed mRNA vaccines against COVID-19 – World Health Organization
Related recommendations:
COVID-19 evidence: a Cochrane round-up.
20 May, 2022 | 11:14h | UTCCOVID-19 evidence: a Cochrane round-up – Cochrane Library
Systematic Review: Thoracic imaging tests for the diagnosis of COVID‐19.
20 May, 2022 | 11:13h | UTCThoracic imaging tests for the diagnosis of COVID‐19 – Cochrane Library
Summary: How accurate is chest imaging for diagnosing COVID-19? – Cochrane Library
M-A: Antibiotic duration for community acquired pneumonia in outpatient children in high-income countries – treatment duration of 3–5 days is equally effective and safe vs. 7–10 days.
20 May, 2022 | 11:10h | UTCRelated:
Antibiotics for Pediatric Pneumonia: Might Less Be Enough? – Annals of Emergency Medicine
Commentary on Twitter
Antibiotic treatment duration for community acquired pneumonia in outpatient children in high-income countries – a systematic review and meta-analysis https://t.co/HxKywgCiXS
A short AB treatment of 3–5 days was equally effective and safe compared to the longer – 7–10 days— Dr. Alex 💊🩺🎮 (@DrAlexxx78) May 17, 2022
Cytomegalovirus blood reactivation in COVID-19 critically ill patients: risk factors and impact on mortality.
20 May, 2022 | 11:06h | UTC
Commentary on Twitter
CMV reactivation in #COVID19 critically ill pts:
🦠frequent! >20% in this study
🧪risk depends on severity of illness/occurrence of secondary bacterial infections in #ICU
🏥 prolonged hospital stay & higher mortality but independent association lacking.
📎 https://t.co/N8JVD1GyPQ pic.twitter.com/KYRtLmxtJg— Intensive Care Medicine (@yourICM) May 18, 2022
SCAI guidelines for the management of patent foramen Ovale.
20 May, 2022 | 11:01h | UTCSCAI Guidelines for the Management of Patent Foramen Ovale – JSCAI
Editorial: New SCAI Guidelines: Trying to Close the Holes in the PFO Literature – JSCAI
Commentary: PFO Closure Guidelines Address Older Adults, Trial-Excluded Groups— Document acknowledges skimpy evidence – MedPage Today (free registration required)
Related:
Advances in the management of cardioembolic stroke associated with patent foramen ovale – The BMJ
Heterogeneity of Treatment Effects in an Analysis of Pooled Individual Patient Data From Randomized Trials of Device Closure of Patent Foramen Ovale After Stroke – JAMA (link to abstract – $ for full-text)