All Posts
Systematic Review | Anti‐IL‐5 therapies for asthma.
14 Jul, 2022 | 12:40h | UTCAnti‐IL‐5 therapies for asthma – Cochrane Library
RCT | Erythropoietin not beneficial for hypoxic-ischemic encephalopathy in newborns.
14 Jul, 2022 | 12:42h | UTCTrial of Erythropoietin for Hypoxic–Ischemic Encephalopathy in Newborns – New England Journal of Medicine (link to abstract – $ for full-text)
Review | Cardiovascular disease in myeloproliferative neoplasms.
14 Jul, 2022 | 12:38h | UTC
How to treat renal cell carcinoma: the current treatment landscape and cardiovascular toxicities.
14 Jul, 2022 | 12:35h | UTC
Cohort Study | Prediction models for celiac disease development in children from high-risk families.
14 Jul, 2022 | 12:31h | UTC
Randomized crossover trial | AI reduces miss rate of precancerous polyps in colorectal cancer screening.
14 Jul, 2022 | 12:29h | UTCNews Release: AI reduces miss rate of precancerous polyps in colorectal cancer screening – Mayo Clinic
Original Study: Impact of Artificial Intelligence on Miss Rate of Colorectal Neoplasia – Gastroenterology
Prevalence of cardiovascular disease in patients with potentially curable malignancies: a national registry dataset analysis.
14 Jul, 2022 | 12:33h | UTC
RCT | Effects of the short stitch technique for midline abdominal closure on incisional hernia.
14 Jul, 2022 | 12:27h | UTC
Review | Anesthesia for tracheal resection and anastomosis.
14 Jul, 2022 | 12:25h | UTC
Review | Neonatal acute kidney injury.
14 Jul, 2022 | 12:21h | UTCNeonatal Acute Kidney Injury – Frontiers in Pediatrics
RCT | Effect of ultrasonography-guided corticosteroid injection vs. placebo added to exercise therapy for Achilles tendinopathy.
14 Jul, 2022 | 12:18h | UTCCommentary: Trial Backs Steroid Shots for Stubborn Achilles Tendon Pain — Corticosteroid bests placebo when combined with resistance exercise therapy – MedPage Today (free registration required)
Commentary on Twitter
In this RCT, corticosteroid injections + exercise therapy was more effective for patients with long-standing Achilles tendinopathy compared to placebo injections + exercise therapy. https://t.co/nkTH0OYL4a
— JAMA Network Open (@JAMANetworkOpen) July 11, 2022
Review | Temporary mechanical circulatory support: devices, outcomes, and future directions.
14 Jul, 2022 | 12:23h | UTC
The Global Retinoblastoma Outcome Study | A prospective, cluster-based analysis of 4,064 patients from 149 countries.
14 Jul, 2022 | 12:16h | UTCInvited Commentary: Retinoblastoma as a lens for correctable disparities worldwide – The Lancet Global Health
M-A | Risk of developing gallbladder cancer in patients with gallbladder polyps detected on Trans-Abdominal ultrasound.
14 Jul, 2022 | 12:14h | UTCRisk of developing gallbladder cancer in patients with gallbladder polyps detected on Trans-Abdominal ultrasound: a systematic review and Meta-Analysis – British Journal of Radiology (link to abstract – $ for full-text)
Related:
Critical Analysis of the Updated Guidelines for Management of Gallbladder Polyps – Annals of Surgical Oncology (if the link is paywalled, try this one)
RCT | Gemcitabine vs. Nab-paclitaxel combined with cisPlatin as first-line treatment in patients with metastatic triple-negative breast cancer.
14 Jul, 2022 | 12:10h | UTC
Commentary on Twitter
Gemcitabine or nab-paclitaxel in combination with cisplatin as first-line treatment in patients with metastatic triple-negative breast cancer: results of a randomized phase 3 trial.https://t.co/RKZYdLRbHq#CancerResearch @natrescancer pic.twitter.com/CrCOCJ2HMu
— Nature Communications (@NatureComms) July 13, 2022
Single-arm study | Long-term benefits of Tagraxofusp for patients with blastic plasmacytoid dendritic cell neoplasm.
14 Jul, 2022 | 12:13h | UTCRelated Study: Tagraxofusp in Blastic Plasmacytoid Dendritic-Cell Neoplasm – New England Journal of Medicine
RCT | Endovascular thrombectomy NOT noninferior to standard bridging thrombolytic with endovascular thrombectomy within 4.5 h of stroke onset.
13 Jul, 2022 | 11:57h | UTCEndovascular thrombectomy versus standard bridging thrombolytic with endovascular thrombectomy within 4·5 h of stroke onset: an open-label, blinded-endpoint, randomised non-inferiority trial – The Lancet (link to abstract – $ for full-text)
Related Study: Thrombectomy alone versus intravenous alteplase plus thrombectomy in patients with stroke: an open-label, blinded-outcome, randomised non-inferiority trial – The Lancet (link to abstract – $ for full-text)
Commentary on Twitter
Two new RCTs show we shouldn't skip bridging intravenous thrombolysis in eligible thrombectomy patients: DIRECT-SAFE (n=293) & SWIFT DIRECT (n=408) @TheLancet @SNISinfo@cvsection https://t.co/Tks14TlaVFhttps://t.co/WaTPn34diy pic.twitter.com/Gcddws8oDf
— Babak Jahromi MD PhD FRCSC (@babaksjahromi) July 9, 2022
RCT | Thrombectomy alone NOT noninferior to intravenous alteplase plus thrombectomy in patients with stroke.
13 Jul, 2022 | 11:55h | UTCThrombectomy alone versus intravenous alteplase plus thrombectomy in patients with stroke: an open-label, blinded-outcome, randomised non-inferiority trial – The Lancet (link to abstract – $ for full-text)
Related Study: Endovascular thrombectomy versus standard bridging thrombolytic with endovascular thrombectomy within 4·5 h of stroke onset: an open-label, blinded-endpoint, randomised non-inferiority trial – The Lancet (link to abstract – $ for full-text)
Commentary on Twitter
Two new RCTs show we shouldn't skip bridging intravenous thrombolysis in eligible thrombectomy patients: DIRECT-SAFE (n=293) & SWIFT DIRECT (n=408) @TheLancet @SNISinfo@cvsection https://t.co/Tks14TlaVFhttps://t.co/WaTPn34diy pic.twitter.com/Gcddws8oDf
— Babak Jahromi MD PhD FRCSC (@babaksjahromi) July 9, 2022
RCT | Myosin inhibition in patients with obstructive hypertrophic cardiomyopathy referred for septal reduction therapy.
13 Jul, 2022 | 11:52h | UTC
Fever therapy in febrile adults: systematic review with meta-analyses and trial sequential analyses.
13 Jul, 2022 | 11:51h | UTC
Clinical prediction models for mortality in patients with covid-19: external validation and individual participant data meta-analysis.
13 Jul, 2022 | 11:49h | UTC
M-A | Home oxygen for moderate hypoxemia in chronic obstructive pulmonary disease.
13 Jul, 2022 | 11:47h | UTCHome oxygen for moderate hypoxaemia in chronic obstructive pulmonary disease: a systematic review and meta-analysis – The Lancet Respiratory Medicine (link to abstract – $ for full-text)
Commentary on Twitter
Home oxygen probably makes little or no difference to 3-year mortality in pts with #COPD and moderate hypoxaemia
Systematic review & meta-analysis from Yves Lacasse & colleagues https://t.co/8wDrkEd1LH pic.twitter.com/UoOqW7hngT
— The Lancet Respiratory Medicine (@LancetRespirMed) July 11, 2022
RCT | Neutropenic versus regular diet for acute leukemia induction chemotherapy.
13 Jul, 2022 | 11:45h | UTCNeutropenic versus regular diet for acute leukaemia induction chemotherapy: randomised controlled trial – BMJ Supportive & Palliative Care (link to abstract – $ for full-text)
Related:
Association between the dietary regimen and infection-related complications in neutropenic high-risk patients with cancer – European Journal of Cancer (link to abstract – $ for full-text)
Neutropenic diets to prevent cancer infections: updated systematic review and meta-analysis – BMJ Supportive & Palliative Care (link to abstract – $ for full-text)
Things We Do For No Reason: Neutropenic Diet – Journal of Hospital Medicine (PDF)
Cohort Study | Risk and timing of noncardiac surgery after transcatheter aortic valve implantation.
13 Jul, 2022 | 11:43h | UTCCommentaries:
Surgery After TAVR: Waiting a Month or More Not Really Better— Prosthesis-patient mismatch, paravalvular regurgitation the bigger issues for surgical candidates – MedPage Today (free registration required)
Commentaries on Twitter
https://twitter.com/JAMANetworkOpen/status/1545120466326749186
https://twitter.com/preopconsult/status/1546167570771894272
ESC Consensus Statement | Digital health in older adults for the prevention and management of cardiovascular diseases and frailty.
13 Jul, 2022 | 11:42h | UTC