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#ESCCongress – Meta-analysis of randomized trials | Angiotensin receptor blockers and Beta-blockers in Marfan syndrome: an individual patient data meta-analysis of randomized trials.
30 Aug, 2022 | 12:15h | UTCNews Release: Drug combination may delay need for surgery in patients with Marfan syndrome – TCTMD
Commentary: ARBs Halve Rate of Aortic Root Enlargement in Marfan: Meta-analysis – TCTMD
#ESCCongress – M-A | Patients with heart failure benefit from dapagliflozin regardless of ejection fraction.
30 Aug, 2022 | 12:14h | UTCNews Release: Patients with heart failure benefit from dapagliflozin regardless of ejection fraction – European Society of Cardiology
Related:
Consensus Statement | Lipoprotein(a) in atherosclerotic cardiovascular disease and aortic stenosis.
30 Aug, 2022 | 12:10h | UTC
Commentary on Twitter
Lipoprotein(a) in atherosclerotic CV and aortic stenosis – a European Atherosclerosis Society consensus statement https://t.co/Bzzpd3Bx8M
#EHJ #ESCCongress #ESCYoung @escardio @ehj_ed @rladeiraslopes pic.twitter.com/ZcqaPe581K
— European Society of Cardiology Journals (@ESC_Journals) August 29, 2022
#ESCCongress | Study shows long-term Evolocumab appears to be safe in patients with established atherosclerotic cardiovascular disease.
30 Aug, 2022 | 12:12h | UTCNews Release: Long-term evolocumab therapy leads to further reductions in cardiovascular events – European Society of Cardiology
Original Article: Evolocumab and Clinical Outcomes in Patients with Cardiovascular Disease – New England Journal of Medicine
Commentary on Twitter
#OriginalResearch SimPub #ESCCongress: In this open-label extension of #FOURIER RCT, long-term evolocumab therapy for >8 yrs was associated w/ persistently low rates and greater reduction in MACE compared w/ delayed treatment initiation among patients w… https://t.co/9g97s4MZSt pic.twitter.com/y5uN53gdKo
— Circulation (@CircAHA) August 29, 2022
Consensus statement on intraoperative and postoperative interventions to reduce pulmonary complications after esophagectomy.
30 Aug, 2022 | 12:09h | UTC
#ESCCongress | In critically ill patients with COVID-19, full-dose anticoagulation reduced thrombotic events but increased the risk of bleeding.
30 Aug, 2022 | 12:12h | UTCNews Release: Trial supports full-dose anticoagulation to prevent blood clots in COVID-19 patients – European Society of Cardiology
Related:
Anticoagulants for people hospitalised with COVID‐19 – Cochrane Library
Commentary on Twitter
#OriginalResearch SimPub #ESCCongress: In the #COVID-PACT 2×2 factorial RCT, full-dose prophylactic anticoagulation, but not the addition of clopidogrel, reduced thrombotic complications but w/ increased bleeding among critically-ill patients w/ COVID-19 https://t.co/UNxFCIC5B9 pic.twitter.com/p5LGmpCGeL
— Circulation (@CircAHA) August 29, 2022
Guidelines | Treatment of symptomatic gallstone disease.
30 Aug, 2022 | 12:09h | UTC
Guideline | Management of medication overuse and medication overuse headache.
30 Aug, 2022 | 12:08h | UTC
RCT | Patient preference and treatment satisfaction with a port delivery system for Ranibizumab vs. intravitreal injections in patients with neovascular age-related macular degeneration.
30 Aug, 2022 | 12:06h | UTCCommentary: Port Delivery System Preferred Over Intravitreal Injection for Patients with nAMD – HCPLive
Commentary on Twitter
In the phase 3 Archway trial, mean overall treatment satisfaction scores were high in port delivery system & intravitreal injection arms; pts with neovascular AMD preferred treatment via the PDS with ranibizumab vs previous intravitreal injections https://t.co/NYf0aKpKaD
— JAMA Ophthalmology (@JAMAOphth) August 25, 2022
Meta analysis of randomized trials | Association of PD-L1 expression and other variables with benefit from immune checkpoint inhibition in advanced gastroesophageal cancer.
30 Aug, 2022 | 12:07h | UTCAssociation of PD-L1 Expression and Other Variables With Benefit From Immune Checkpoint Inhibition in Advanced Gastroesophageal Cancer: Systematic Review and Meta-analysis of 17 Phase 3 Randomized Clinical Trials – JAMA Oncology (free for a limited period)
Commentary on Twitter
In this meta-analysis of >11,000 patients with advanced gastroesophageal cancer, tissue PD-L1 expression — more than other variables besides microsatellite-high — identified varying degrees of benefit from immunotherapy-containing therapy. https://t.co/oUEDIEqLFj
— JAMA Oncology (@JAMAOnc) August 25, 2022
Single-center RCT | Effectiveness of intrarectal povidone-iodine cleansing plus formalin disinfection of the needle tip in decreasing infectious complications after transrectal prostate biopsy.
30 Aug, 2022 | 12:05h | UTCEffectiveness of Intrarectal Povidone-Iodine Cleansing plus Formalin Disinfection of the Needle Tip in Decreasing Infectious Complications after Transrectal Prostate Biopsy: A Randomized Controlled Trial – The Journal of Urology (link to abstract – $ for full-text)
Review | Therapeutic payload delivery to the myocardium: Evolving strategies and obstacles.
30 Aug, 2022 | 12:04h | UTCTherapeutic payload delivery to the myocardium: Evolving strategies and obstacles – JTCVS Open
Review | Invasive and noninvasive cardiovascular monitoring options for cardiac surgery.
30 Aug, 2022 | 12:03h | UTCInvasive and noninvasive cardiovascular monitoring options for cardiac surgery – JTCVS Open
Meta-analysis of observational studies | In patients with hepatocellular carcinoma, intraoperative blood salvage during liver transplantation appears safe.
30 Aug, 2022 | 12:03h | UTC
Salt substitutes vs. regular salt: a quick look.
30 Aug, 2022 | 12:02h | UTCSalt substitutes vs. regular salt: a quick look – Evidently Cochrane
Original Study: Replacing salt with low‐sodium salt substitutes (LSSS) for cardiovascular health in adults, children and pregnant women – Cochrane Library
Related:
Effects of salt substitutes on clinical outcomes: a systematic review and meta-analysis – Heart (link to abstract – $ for full-text)
RCT: Reduced-sodium added-potassium salt substitute reduces blood pressure in hypertensive patients
Potassium Enriched Salt Substitution Could Prevent a Large Number of Cardiovascular Deaths
Commentary on Twitter
https://twitter.com/CochraneLibrary/status/1563130897159028737
M-A | Utility of the Ages and Stages Questionnaire to identify developmental delay in children aged 12 to 60 months.
30 Aug, 2022 | 12:00h | UTCUtility of the Ages and Stages Questionnaire to Identify Developmental Delay in Children Aged 12 to 60 Months: A Systematic Review and Meta-analysis – JAMA Pediatrics (free for a limited period)
Case series of acute cholecystitis associated with the use of Glucagon-Like Peptide-1 Receptor agonists reported to the US Food and Drug Administration.
30 Aug, 2022 | 11:59h | UTCAcute Cholecystitis Associated With the Use of Glucagon-Like Peptide-1 Receptor Agonists Reported to the US Food and Drug Administration – JAMA Internal Medicine (free for a limited period)
RCT | Colorectal Endoscopic Stenting Trial (CReST) for obstructing left-sided colorectal cancer.
30 Aug, 2022 | 11:58h | UTC
Cohort Study | Outcomes of patients with sporadic non-functioning pancreatic neuroendocrine neoplasms no larger than 2 cm under active surveillance.
30 Aug, 2022 | 11:57h | UTC
Development and external validation of DISPAIR fistula risk score for clinically relevant postoperative pancreatic fistula risk after distal pancreatectomy.
30 Aug, 2022 | 11:56h | UTC
M-A | Midodrine for the prevention of vasovagal syncope.
30 Aug, 2022 | 11:56h | UTCRelated: RCT: Midodrine can reduce the recurrence of vasovagal syncope.
Cohort Study | Comparing kidney health outcomes in children, adolescents, and adults with focal segmental glomerulosclerosis.
30 Aug, 2022 | 11:53h | UTC
Commentary on Twitter
https://twitter.com/JAMANetworkOpen/status/1562922771730305030
M-A | Urban-rural differences in hypertension prevalence in low-income and middle-income countries, 1990–2020.
30 Aug, 2022 | 11:55h | UTCNews Release: Study shows urban-rural differences in hypertension prevalence in low-income and middle-income countries – News Medical
Commentary on Twitter
🚨paper alert! In LMICs, is #hypertension more prevalent in urban or rural areas?
Nearly 300 studies from 66 LMICs (>19 million participants) revealed that the rate of change from 1990-2022 appears greater in rural.
It has been so nice contributing to this tremendous work!🤩 https://t.co/EjbRpf83HJ
— Adna Curto (@adna_otti) August 27, 2022
Study shows an increasing incidence of hypertensive disorders in pregnancy.
30 Aug, 2022 | 11:52h | UTCCommentaries:
Increased incidence of hypertensive disorders of pregnancy in young Americans – News Medical
Hypertensive Disorders in Pregnancy on the Rise – AJMC
Commentary on Twitter
Independent birth cohort effect on rates of hypertensive disorders of pregnancy higher incidence in younger generations and persistent racial and ethnic disparities. Increased awareness even among young pregnant people is needed. #OAResearch https://t.co/wNwIZTYLHZ
— JAMA Network Open (@JAMANetworkOpen) August 24, 2022
#ESCCongress – RCT | In patients with severe ischemic left ventricular systolic dysfunction under optimal medical therapy, revascularization by PCI did not improve outcomes.
29 Aug, 2022 | 12:38h | UTCPercutaneous Revascularization for Ischemic Left Ventricular Dysfunction – New England Journal of Medicine (link to abstract – $ for full-text)
News Release: Coronary stenting does not benefit patients with severe left ventricular dysfunction – European Society of Cardiology
Commentary on Twitter
REVIVED-BCIS2: In patients with a low left ventricular ejection fraction and viable myocardium, PCI did not reduce the incidence of death from any cause or hospitalization for heart failure. #ESCCongress https://t.co/XtZlkJ7GAf pic.twitter.com/6uMNemzkyN
— NEJM (@NEJM) August 27, 2022