All Posts
RCT | Intravenous iron did not significantly reduce hospital admissions in patients with heart failure and iron deficiency.
7 Nov, 2022 | 12:48h | UTCCommentaries:
IRONMAN Misses but Lends Support to IV Iron Repletion in HF – TCTMD
Cohort Study | Preoperative hemodialysis timing and postoperative mortality in patients with end-stage kidney disease.
7 Nov, 2022 | 12:46h | UTCAssociation Between Preoperative Hemodialysis Timing and Postoperative Mortality in Patients With End-stage Kidney Disease – JAMA (free for a limited period)
Editorial: Optimal Timing of Hemodialysis Before Surgery – JAMA (free for a limited period)
Commentary from the author on Twitter (thread – click for more)
1/
In @JAMA_current, we asked: Is the timing of hemodialysis before surgery associated with postoperative mortality?The answer: YES
Here’s what we found:https://t.co/ZQl0SHZpAn
— Vikram Fielding-Singh, MD, JD (@vikramfs) November 3, 2022
Expert consensus | Use of sponge-assisted endoluminal vacuum therapy for the treatment of colorectal anastomotic leaks.
7 Nov, 2022 | 12:42h | UTC
Commentary on Twitter
https://twitter.com/BjsOpen/status/1585594658863939586
Consensus Paper | State-of-the-art CT and MR imaging and assessment of atherosclerotic carotid artery disease.
7 Nov, 2022 | 12:44h | UTC
Guidelines for empirical antibacterial therapy of sepsis in adults.
7 Nov, 2022 | 12:40h | UTC
Updated systematic review on cannabis and other plant-based treatments for chronic pain.
7 Nov, 2022 | 12:39h | UTCRelated:
Systematic Review: Cannabis-based products for chronic pain.
Podcast: #338 LIVE! Medical Cannabis: Is it still dope? – The Curbsiders
M-A: Birth outcomes of neonates exposed to marijuana in utero.
Cannabis-related allergies: an international overview and consensus recommendations.
Review: Cannabis-based medicines and medical cannabis for chronic neuropathic pain.
Cannabis products are being sold as sleep remedies – here’s the evidence about their effectiveness.
Guideline: Medical cannabis or cannabinoids for chronic pain.
NICE Guideline: Cannabis-Based Medicinal Products
Short Review: Drug Interactions with Cannabinoids
Meta-Analysis: Cannabinoids Not Effective for Cancer-Related Pain
Review: Considerations for cannabinoids in perioperative care by anesthesiologists.
Review: Cannabis-based Medicines and the Perioperative Physician
Perspective: If You Smoke Pot, Your Anesthesiologist Needs To Know
RCT | Effectiveness of tonsillectomy vs. modified uvulopalatopharyngoplasty in patients with tonsillar hypertrophy and sleep apnea.
7 Nov, 2022 | 12:36h | UTCEffectiveness of Tonsillectomy vs Modified Uvulopalatopharyngoplasty in Patients With Tonsillar Hypertrophy and Obstructive Sleep Apnea: The TEAMUP Randomized Clinical Trial – JAMA Otolaryngology—Head & Neck Surgery (free for a limited period)
RCT | Efficacy of a digital behavioral therapeutic application to improve glycemic control in adults with Type 2 DM.
7 Nov, 2022 | 12:33h | UTCCommentary: Smartphone-delivered CBT improves glycemic control in people with type 2 diabetes – medwire News
M-A | Association of intraventricular fibrinolysis with clinical outcomes in intracerebral hemorrhage.
7 Nov, 2022 | 12:31h | UTCAssociation of Intraventricular Fibrinolysis With Clinical Outcomes in Intracerebral Hemorrhage: An Individual Participant Data Meta-Analysis – Stroke (free for a limited period)
Commentary on Twitter
#STROKE #IntraventricularFibrinolysis is associated with better functional outcomes and reduced mortality in #ICH patients with #IVH, with treatment effect linked to an early time window <48h #MetaAnalysis https://t.co/hRQJ9w5ppv @WendyZiai @GuidoFalconeMD @sheth_kevin pic.twitter.com/INeDIIHCBw
— Stroke AHA/ASA (@StrokeAHA_ASA) September 30, 2022
RCT | Efficacy of prune juice containing sorbitol, pectin, and polyphenol in chronic constipation.
7 Nov, 2022 | 12:34h | UTCPrune Juice Containing Sorbitol, Pectin, and Polyphenol Ameliorates Subjective Complaints and Hard Feces While Normalizing Stool in Chronic Constipation: A Randomized Placebo-Controlled Trial – American Journal of Gastroenterology (free for a limited period)
Commentary on Twitter
In the 📕#RedJournal — Prune Juice Containing Sorbitol, Pectin, and Polyphenol Ameliorates Subjective Complaints and Hard Feces While Normalizing Stool in Chronic Constipation: A Randomized Placebo-Controlled Trial
Koyama, et al.👉 https://t.co/IFnZTfnw8I@AmCollegeGastro pic.twitter.com/C244dAWNIa
— AJG – The American Journal of Gastroenterology (@AmJGastro) October 19, 2022
RCT | Naltrexone-bupropion and behavior therapy, alone and combined, for binge-eating disorder.
7 Nov, 2022 | 12:27h | UTCNews Release: People With Binge-eating Disorder Benefit From Specific Behavioral Therapy and Medication – Yale School of Medicine
Commentary: Behavioral Therapy Plus Naltrexone-Bupropion Combination May Reduce Binge Eating – Psychiatric News Alert
RCT | Efficacy of drug-eluting stent vs. bare metal stent for symptomatic femoropopliteal peripheral artery disease.
7 Nov, 2022 | 12:29h | UTCEfficacy of a Drug-Eluting Stent Versus Bare Metal Stents for Symptomatic Femoropopliteal Peripheral Artery Disease: Primary Results of the EMINENT Randomized Trial – Circulation (free for a limited period)
Commentary on Twitter
https://twitter.com/CircAHA/status/1585005809955651584
RCT | Low-dose immunotherapy (nivolumab) may improve outcomes when added to chemotherapy for head and neck cancer.
7 Nov, 2022 | 12:26h | UTCLow-Dose Immunotherapy in Head and Neck Cancer: A Randomized Study – Journal of Clinical Oncology (link to abstract – $ for full-text)
Commentary from the author on Twitter
Low-Dose Immunotherapy has made immunotherapy more accessible, and has brought down the cost of therapy from 60-80 lakhs to below 5.0 lakhs per year. Hugh cost saving. A step towards atmanirbhar Bharat. @PMOIndia @TOIIndiaNews @ndtv @ZeeNews @the_hindu https://t.co/c0WuC9Wlfk
— Dr (Prof). Vijay Patil (@DrVijayPatil11) October 21, 2022
Post-trial follow-up | Long-term outcomes with stereotactic radiosurgery vs. whole-brain RT for resected brain metastasis.
7 Nov, 2022 | 12:22h | UTCAssociation of Long-term Outcomes With Stereotactic Radiosurgery vs Whole-Brain Radiotherapy for Resected Brain Metastasis: A Secondary Analysis of The N107C/CEC.3 (Alliance for Clinical Trials in Oncology/Canadian Cancer Trials Group) Randomized Clinical Trial – JAMA Oncology (link to abstract – $ for full-text)
Commentary: Survivors face less late cognitive deterioration after stereotactic radiosurgery than WBRT – medwire News
Original Study: Postoperative stereotactic radiosurgery compared with whole brain radiotherapy for resected metastatic brain disease (NCCTG N107C/CEC·3): a multicentre, randomised, controlled, phase 3 trial – The Lancet Oncology (link to abstract – $ for full-text)
Commentary on Twitter
In pts w limited brain mets after surgical resection, secondary analysis of rand phase 3 trial shows more patients declined significantly in 1 or more cognitive tests with whole brain radiation therapy (WBRT) vs stereotactic radiosurgery (SRS) https://t.co/6nSCO5kSpW #BTSM
— JAMA Oncology (@JAMAOnc) October 22, 2022
Crossover RCT | Efficacy of low-dose Empagliflozin as an adjunct to hybrid closed-loop insulin therapy in adults with Type 1 DM.
7 Nov, 2022 | 12:24h | UTCLow-Dose Empagliflozin as Adjunct to Hybrid Closed-Loop Insulin Therapy in Adults With Suboptimally Controlled Type 1 Diabetes: A Randomized Crossover Controlled Trial – Diabetes Care (link to abstract – $ for full-text)
Review | Early appropriate diagnostics and treatment of MDR Gram-negative infections.
7 Nov, 2022 | 12:19h | UTCRelated:
Commentary on Twitter
This is a ⚡fantastic article⚡
by super 🌟s Dr. Bassetti & @davidvanduin @jac_amr
We really need more adoption to RDTs coupled with stewardship programs
Early appropriate diagnostics and treatment of MDR Gram-negative infections #IDTwitter #MedEd https://t.co/h6eOvK2iH8 pic.twitter.com/WBjogJ6IYu— Antibiotic Steward Bassam Ghanem 🅱️C🆔🅿️🌟 (@ABsteward) September 14, 2022
Under a https://creativecommons.org/licenses/by/4.0/ license
Review | The threat of multidrug-resistant/extensively drug-resistant Gram-negative respiratory infections.
7 Nov, 2022 | 12:17h | UTCRelated:
Review | How and when to manage respiratory infections out of hospital.
7 Nov, 2022 | 12:15h | UTCHow and when to manage respiratory infections out of hospital – European Respiratory Review
M-A | Prevalence, risk factors and treatments for post-COVID-19 breathlessness.
7 Nov, 2022 | 12:14h | UTC
Review | Clinical significance of the neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio in acute exacerbations of COPD.
7 Nov, 2022 | 12:11h | UTC
Review | Non-Aspergillus mold lung infections.
7 Nov, 2022 | 11:51h | UTCNon-Aspergillus mould lung infections – European Respiratory Review
Review | Respiratory viruses: their importance and lessons learned from COVID-19.
7 Nov, 2022 | 11:54h | UTC
A multinational Delphi consensus to end the COVID-19 public health threat.
4 Nov, 2022 | 14:01h | UTCA multinational Delphi consensus to end the COVID-19 public health threat – Nature
Phase 2 RCT | Single-dose Psilocybin for a treatment-resistant episode of major depression.
4 Nov, 2022 | 13:57h | UTCSingle-Dose Psilocybin for a Treatment-Resistant Episode of Major Depression – New England Journal of Medicine (link to abstract – $ for full-text)
Commentaries:
Largest trial to date shows that psilocybin reduces depression symptoms – King’s College London
Related:
Research: “Magic mushrooms” for treatment-resistant depression
Commentary on Twitter
A single 25-mg dose of psilocybin was more effective than a 1-mg dose at alleviating treatment-resistant depression over a period of 3 weeks. The effect was attenuated at 12 weeks. https://t.co/sM1mISArvb pic.twitter.com/9YRaxfcpNT
— NEJM (@NEJM) November 2, 2022
RCT | Once-weekly Semaglutide effective for weight loss in adolescents with obesity.
4 Nov, 2022 | 13:59h | UTCOnce-Weekly Semaglutide in Adolescents with Obesity – New England Journal of Medicine (link to abstract – $ for full-text)
Commentaries:
STEP TEENS: High-dose semaglutide weight loss benefits shown in adolescents – medwire News
Trial Shows Weight-Loss Drug Works in Teens – HealthDay
Commentary on Twitter
In this trial, adolescents with obesity assigned to weekly subcutaneous semaglutide plus lifestyle intervention had a greater reduction in BMI than those who received lifestyle intervention alone. https://t.co/yiFseP38xa pic.twitter.com/uRqkFfon1s
— NEJM (@NEJM) November 2, 2022