All Posts | Links Medicus - Free Medical News & Perspective

M-A | Effect of breathwork on stress and mental health

15 Jan, 2023 | 20:28h | UTC

Effect of breathwork on stress and mental health: A meta-analysis of randomised-controlled trials – Scientific Reports

Commentary: Review and meta-analysis suggests breathwork may be effective for improving stress and mental health – News Medical

Commentary on Twitter

A meta-analysis in @SciReports shows that breathwork may be effective for improving stress and mental health. The authors also call for nuanced research approaches with low risk-of-bias study designs to avoid a miscalibration between hype and evidence. https://t.co/iTLGE2AsPT pic.twitter.com/SM5FBL2idK

— Nature Portfolio (@NaturePortfolio) January 12, 2023

Cohort Study | Trends in antipsychotic prescribing to children and adolescents in England

15 Jan, 2023 | 20:26h | UTC

Trends in antipsychotic prescribing to children and adolescents in England: cohort study using 2000–19 primary care data – The Lancet Psychiatry

News Release: Researchers reveal worrying rise in antipsychotic prescriptions for children and young people – University of Manchester

Commentary on Twitter

https://twitter.com/TheLancetPsych/status/1613086964848156672

UK National case series of group A streptococcus pleural empyema in children: clinical and microbiological features

15 Jan, 2023 | 20:24h | UTC

National case series of group A streptococcus pleural empyema in children: clinical and microbiological features – The Lancet Infectious Diseases

Commentary from the author on Twitter (thread – click for more)

huge amount of recent interest in invasive group A streptococcus (iGAS) infection in children
but up until now little patient-level clinical data on this spike in cases
we hope our case series @TheLancetInfDis will help address this knowledge gap https://t.co/75kV7FVmST 1/n pic.twitter.com/ytKyRu8MYi

— Thomas Christie Williams (@Williams_T_C) January 10, 2023

ESMO Guideline | Venous thromboembolism in cancer patients

15 Jan, 2023 | 20:21h | UTC

Venous thromboembolism in cancer patients: ESMO Clinical Practice Guideline – Annals of Oncology

Cancer-associated venous thromboembolism – Nature Reviews Disease Primers

Infographic: Cancer-associated venous thromboembolism – Nature Reviews Disease Primers

NCCN Guideline: Cancer-Associated Venous Thromboembolic Disease.

ASH 2021 guidelines for prevention and treatment of venous thromboembolism in patients with cancer

Review: venous and arterial thromboembolism in patients with cancer.

M-A: Extended thromboprophylaxis after hospital discharge for medically ill patients with cancer – Extended thromboprophylaxis is not associated with a reduced rate of venous thromboembolic events and is associated with increased risk of hemorrhage

Systematic review: Primary prophylaxis for venous thromboembolism in ambulatory cancer patients receiving chemotherapy

AHA Scientific Statement | Palliative care across the life span for children with heart disease

15 Jan, 2023 | 20:19h | UTC

Palliative Care Across the Life Span for Children With Heart Disease: A Scientific Statement From the American Heart Association – Circulation: Cardiovascular Quality and Outcomes

Top Things to Know: Palliative Care Across Lifespan for Children With Heart Disease – American Heart Association

Commentary: Palliative Care Across the Lifespan for Children with Heart Disease – American Heart Association

M-A | Transfusion guidelines in traumatic brain injury

15 Jan, 2023 | 20:15h | UTC

Transfusion Guidelines in Traumatic Brain Injury: A Systematic Review and Meta-Analysis of the Currently Available Evidence – Neurotrauma Reports

Consensus Paper | Revision of classification system for reporting on skin biopsies of melanocytic lesions

15 Jan, 2023 | 20:17h | UTC

Revision of the Melanocytic Pathology Assessment Tool and Hierarchy for Diagnosis Classification Schema for Melanocytic Lesions: A Consensus Statement – JAMA Network Open

Commentaries:

Classification system for reporting on skin biopsies of melanocytic lesions – University of California – Los Angeles Health Sciences

MPATH-Dx Version 2.0 Simplifies Classification of Melanoma – HealthDay

Commentary on Twitter

American and international #dermatopathologists revise Melanocytic Pathology Assessment Tool and Hierarchy for Diagnosis schema. MPATH-Dx V2.0 improves standardized diagnostic reporting and patient management of #melanoma. https://t.co/G0fluzq5fs

— JAMA Network Open (@JAMANetworkOpen) January 12, 2023

RCT | Ecopipam for Tourette Syndrome

15 Jan, 2023 | 20:09h | UTC

Ecopipam for Tourette Syndrome: A Randomized Trial – Pediatrics

Commentary: Ecopipam May Reduce Tics in Children With Tourette Syndrome – Psychiatric News Alert

Commentary on Twitter

Ecopipam, a selective D1-like receptor antagonist, is in development for children & adolescents with Tourette syndrome. Can ecopipam achieve a clinically meaningful reduction in tics without the disadvantages of D2-like receptor antagonists? https://t.co/GXxnPsP74C #Pediatrics pic.twitter.com/14fwu4npJi

— AAP Pediatrics (@aap_peds) January 11, 2023

SR | Baclofen for alcohol use disorder

15 Jan, 2023 | 20:11h | UTC

Baclofen for alcohol use disorder – Cochrane Library

Summary: Baclofen for alcohol use disorder – Cochrane Library

Synopsis | Endocrine Society hypercalcemia of malignancy guidelines

15 Jan, 2023 | 22:13h | UTC

Endocrine Society Hypercalcemia of Malignancy Guidelines – JAMA Oncology (free for a limited period)

Original article: Guideline | Treatment of hypercalcemia of malignancy in adults

RCT | Lebrikizumab in combination with topical corticosteroids in adolescents and adults with moderate-to-severe atopic dermatitis

15 Jan, 2023 | 20:07h | UTC

Efficacy and Safety of Lebrikizumab in Combination With Topical Corticosteroids in Adolescents and Adults With Moderate-to-Severe Atopic Dermatitis: A Randomized Clinical Trial (ADhere) – JAMA Dermatology

Commentary on Twitter

Does blocking the IL-13 cytokine w/ lebrikizumab combined w/ topical therapy provide clinical benefit in atopic eczema? This study reflecting real-world use patterns suggests a benefit. https://t.co/apUvYO3Jqv

— JAMA Dermatology (@JAMADerm) January 13, 2023

RCT | MRI–guided vs. CT–guided stereotactic body radiotherapy for prostate cancer

15 Jan, 2023 | 20:05h | UTC

Magnetic Resonance Imaging–Guided vs Computed Tomography–Guided Stereotactic Body Radiotherapy for Prostate Cancer: The MIRAGE Randomized Clinical Trial – JAMA Oncology

News Release: MRI-guided radiotherapy produces fewer side effects and better quality of life for patients with localized prostate cancer – University of California

Commentary from the author on Twitter (thread – click for more)

Pleased to share the primary endpoint results of the randomized phase III MIRAGE trial evaluating whether aggressive margin reduction with MRI-guidance leads to reduced toxicity in the context of prostate SBRT, out today in @JAMAOncology https://t.co/5ZKElUR4uk (1/n)

— Amar Kishan (@AmarUKishan) January 12, 2023

RCT | In patients undergoing cardiac surgery, intravenous high-dose selenium did not reduce morbidity or mortality

15 Jan, 2023 | 20:00h | UTC

Effect of High-Dose Selenium on Postoperative Organ Dysfunction and Mortality in Cardiac Surgery Patients: The SUSTAIN CSX Randomized Clinical Trial – JAMA Surgery

Commentary on Twitter

In this study, high-dose sodium selenite was not effective in reducing the development of organ dysfunction and death in high-risk cardiac surgery patients. @CStoppe @CriticalCa https://t.co/H3HR1u1HhU

— JAMA Surgery (@JAMASurgery) January 12, 2023

M-A | Outcomes and complications of pars plana vitrectomy for tractional retinal detachment in people with diabetes

15 Jan, 2023 | 20:02h | UTC

Outcomes and Complications of Pars Plana Vitrectomy for Tractional Retinal Detachment in People With Diabetes: A Systematic Review and Meta-analysis – JAMA Ophthalmology

Commentary: Pars Plana Vitrectomy Associated with High Retinal Reattachment, but Low Final Vision – HCP Live

Commentary on Twitter

Study findings suggest that pars plana vitrectomy is associated with high anatomic reattachment but limited final vision postoperatively, which may be useful for the counseling of patients with diabetic tractional retinal detachment. https://t.co/Comj3VOpUF

— JAMA Ophthalmology (@JAMAOphth) January 12, 2023

M-A | Costs and clinical benefits of enhanced recovery after surgery (ERAS) in pancreaticoduodenectomy

15 Jan, 2023 | 19:58h | UTC

Costs and clinical benefits of enhanced recovery after surgery (ERAS) in pancreaticoduodenectomy: an updated systematic review and meta-analysis – Journal of Cancer Research and Clinical Oncology

Guidelines for Perioperative Care for Pancreatoduodenectomy: Enhanced Recovery After Surgery (ERAS) Recommendations 2019 – World Journal of Surgery

Complete List of Enhanced Recovery After Surgery (ERAS) Society Guidelines

Top 100 Most-Cited Articles on Enhanced Recovery After Surgery: A Bibliometric Analysis and Visualized Study – Frontiers in Surgery

Crossover RCT | Preliminary study showed closed-loop insulin delivery might improve glycemic control in some adults with Type 2 DM

15 Jan, 2023 | 19:56h | UTC

Fully automated closed-loop insulin delivery in adults with type 2 diabetes: an open-label, single-center, randomized crossover trial – Nature Medicine

News Release: Artificial pancreas successfully trialed for use by type 2 diabetes patients – University of Cambridge

Commentary: Artificial Pancreas Device May Help Folks With Type 2 Diabetes – HealthDay

RCT | Cosmetic results and side effects of accelerated partial-breast irradiation vs. whole-breast irradiation for low-risk invasive carcinoma of the breast

15 Jan, 2023 | 19:53h | UTC

Cosmetic Results and Side Effects of Accelerated Partial-Breast Irradiation Versus Whole-Breast Irradiation for Low-Risk Invasive Carcinoma of the Breast: The Randomized Phase III IRMA Trial – Journal of Clinical Oncology (link to abstract – $ for full-text)

Commentary from the author on Twitter

5yr results of the phase 3 #IRMAtrial: EBRT #APBI b.i.d. associated with slightly increased rate of moderate soft tissue and bone toxicity and a slightly inferior cosmesis, though overall toxicity was in an acceptable range @JCO_ASCO #BCSM @OncoAlert https://t.co/8LHE2ut3t2

— Bruno Meduri (@brunomeduri) January 9, 2023