All Posts
Position Paper | Enteral nutrition in preterm infants
30 Jan, 2023 | 00:54h | UTC
Conditional power: how likely is trial success?
30 Jan, 2023 | 00:52h | UTCConditional Power: How Likely Is Trial Success? – JAMA (free for a limited period)
Commentary on Twitter
JAMA Guide to Statistics and Methods article examines conditional power, calculated while a trial is ongoing and based on both the currently observed data and an assumed treatment effect for future patients. https://t.co/h9Ky9rgF61
— JAMA (@JAMA_current) January 23, 2023
RCT | Disposable elevator cap duodenoscopes reduce microbial contamination during ERCP
30 Jan, 2023 | 00:49h | UTC
Commentary on Twitter
In this RCT of 520 ERCP patients, disposable elevator cap duodenoscopes reduced persistent contamination (RR 0.34, 95% CI 0.16–0.75), with no differences in performance (technical success 94.6% vs. 90.7%, P=.13) or safety outcomes. https://t.co/km87WyxsvR
— JAMA Internal Medicine (@JAMAInternalMed) January 26, 2023
Estimated prevalence and clinical manifestations of UBA1 variants associated with VEXAS syndrome in a clinical population
30 Jan, 2023 | 00:51h | UTCEstimated Prevalence and Clinical Manifestations of UBA1 Variants Associated With VEXAS Syndrome in a Clinical Population – JAMA (free for a limited period)
Commentaries:
Study provides an estimate of people in the United States with VEXAS syndrome – News Medical
Prevalence of VEXAS Syndrome Identified in U.S. Health System – HealthDay
SR | There is insufficient evidence to recommend corticosteroids for the management of cancer‐related fatigue
30 Jan, 2023 | 00:47h | UTC
SR | Prognosis of adults and children following a first unprovoked seizure
30 Jan, 2023 | 00:45h | UTCPrognosis of adults and children following a first unprovoked seizure – Cochrane Library
Summary: Predicting a second seizure after a single unprovoked seizure – Cochrane Library
M-A | The optimal timing and intervention to reduce mortality for necrotizing pancreatitis
30 Jan, 2023 | 00:44h | UTCRelated:
Research: Endoscopic or Surgical Step-up Approach for Infected Necrotising Pancreatitis
Evidence-Based Approach to the Surgical Management of Acute Pancreatitis – The Surgery Journal
Aggressive or Moderate Fluid Resuscitation in Acute Pancreatitis – New England Journal of Medicine (link to abstract – $ for full-text)
Acute Pancreatitis: Diagnosis and Treatment – Drugs
Evidence-Based Disposition of Acute Pancreatitis – emDocs
Pancreatitis – National Institute for Health and Care Excellence
Toward nutrition improving outcome of critically ill patients: how to interpret recent feeding RCTs?
30 Jan, 2023 | 00:42h | UTC
RCT | Simple aspiration versus drainage for complete pneumothorax
30 Jan, 2023 | 00:40h | UTCSimple Aspiration Versus Drainage for Complete Pneumothorax: A Randomized Non-Inferiority Trial – Am J Respir Crit Care Med (link to abstract – $ for full-text)
Review | A clinical approach to tubulopathies in children and young adults
30 Jan, 2023 | 00:36h | UTCA clinical approach to tubulopathies in children and young adults – Pediatric Nephrology
Evaluation of systemic medications associated with surgically treated cataract among US adults
30 Jan, 2023 | 00:38h | UTCCommentary: Some systemic medications may be associated with increased cataract risk – 2 Minute Medicine
SR | Perioperative clinical practice guidelines for care of older adults living with frailty
30 Jan, 2023 | 00:34h | UTC
RCT | Effect of second-stage pushing timing on postpartum pelvic floor morbidity
30 Jan, 2023 | 00:31h | UTCEffect of Second-Stage Pushing Timing on Postpartum Pelvic Floor Morbidity: A Randomized Controlled Trial – Obstetrics & Gynecology (free for a limited period)
Commentary on Twitter
How does timing of pushing in obstetrics impact future pelvic floor health? #freearticle https://t.co/VPZgVt8JnU pic.twitter.com/gSiTGN1Vdv
— The Green Journal (@greenjrnl) January 24, 2023
Review | Impact of fatigue on anesthesia providers
30 Jan, 2023 | 00:33h | UTCImpact of fatigue on anaesthesia providers: a scoping review – British Journal of Anaesthesia
M-A | Permanent compared with absorbable suture in apical prolapse surgery
30 Jan, 2023 | 00:29h | UTCPermanent Compared With Absorbable Suture in Apical Prolapse Surgery: A Systematic Review and Meta-analysis – Obstetrics & Gynecology (free for a limited period)
Commentary on Twitter
Should you use permanent or absorbable suture for apical prolapse? https://t.co/G8nkMQgUQV pic.twitter.com/LwBwyS1WV8
— The Green Journal (@greenjrnl) January 27, 2023
RCT | Adjuvant temozolomide with or without interferon alfa in patients with newly diagnosed high-grade gliomas
30 Jan, 2023 | 00:27h | UTCCommentary: Interferon Alfa Improves Upon Standard Care in High Grade Glioma – Cancer Therapy Advisor
Commentary on Twitter
This phase 3 clinical trial demonstrated interferon alfa + temozolomide prolonged survival time in patients with newly diagnosed high-grade gliomas by median 8 months (18% vs 9% 5yr overall survival), especially with MGMT promoter unmethylated tumors. https://t.co/2yOssnF97G
— JAMA Network Open (@JAMANetworkOpen) January 27, 2023
RCT | IV ferric carboxymaltose vs. oral ferrous fumarate in anemic children with inflammatory bowel disease
30 Jan, 2023 | 00:18h | UTC
Cohort Study | Risk of malignant neoplasms of the gastrointestinal tract after blood or marrow transplant
30 Jan, 2023 | 00:23h | UTCMalignant Neoplasms of the Gastrointestinal Tract After Blood or Marrow Transplant – JAMA Oncology (link to abstract – $ for full-text)
Commentary: Risk of Subsequent Gastrointestinal Tract Malignancies After Blood or Marrow Transplantation – The ASCO Post
Commentary on Twitter
Exposure to cytarabine, etoposide and anthracyclines & chronic graft vs. host disease increase risk of colorectal, liver & esophageal cancer after BMT, providing evidence for appropriate evaluation & management in high-risk populations. https://t.co/UENFM1UWRw
— JAMA Oncology (@JAMAOnc) January 23, 2023
Guideline | Management of severe bronchiolitis in infants under 12 months admitted to a pediatric critical care unit
27 Jan, 2023 | 12:32h | UTC
Commentary on Twitter
https://twitter.com/yourICM/status/1610855347203309568
Cohort Study | Exercise volume vs. intensity and the progression of coronary atherosclerosis in middle-aged and older athletes
27 Jan, 2023 | 12:29h | UTCCommentaries:
Exercise Intensity, Not Volume, Linked to Atherosclerosis Progression in Men – TCTMD
Intense exercise encourages coronary artery calcification – News Medical
Commentary on Twitter
#OriginalResearch: MARC-2 Study reports that Very vigorous intensity exercise is associated with progression of CAC among middle-aged and older athletes @VAengevaeren @ThijsEijsvogels #AHAJournals https://t.co/rdZw3U8yxU pic.twitter.com/Uzqg1TbtEP
— Circulation (@CircAHA) January 6, 2023
Overuse of medications in low- and middle-income countries: a scoping review
27 Jan, 2023 | 12:31h | UTC
AHA Report | Heart disease and stroke statistics in the US—2023 update
27 Jan, 2023 | 12:27h | UTCNews Release: COVID toll realized: CVD deaths take big jump, especially among certain populations – American Heart Association
Commentaries:
AHA Presents Up-To-Date Statistics for Cardiovascular Disease – HealthDay
Sobering statistics from the AHA’s 2023 heart disease and stroke update – News Medical
RCT | Higher protein dosing did not improve outcomes in critically ill patients with high nutritional risk
27 Jan, 2023 | 12:24h | UTCThe effect of higher protein dosing in critically ill patients with high nutritional risk (EFFORT Protein): an international, multicentre, pragmatic, registry-based randomised trial – The Lancet (link to abstract – $ for full-text)
Commentary on Twitter (thread – click for more)
Researchers aimed to test the hypothesis that a higher dose of protein provided to critically ill patients would improve clinical outcomes.
Here's what they found 🧵 /4 https://t.co/C5JswTr82o
— The Lancet (@TheLancet) January 26, 2023
Perspective | Is it time to retire the diagnosis “hypertensive emergency”?
27 Jan, 2023 | 12:26h | UTC
RCT | Sodium bicarbonate over 2 years was not beneficial for kidney transplant recipients with metabolic acidosis
27 Jan, 2023 | 12:23h | UTCSodium bicarbonate for kidney transplant recipients with metabolic acidosis in Switzerland: a multicentre, randomised, single-blind, placebo-controlled, phase 3 trial – The Lancet (link to abstract – $ for full-text)