All Posts
RCT | Laser no better than sham treatment for genitourinary syndrome of menopause
8 Feb, 2023 | 12:17h | UTCLaser versus sham for genitourinary syndrome of menopause: A randomised controlled trial – BJOG (link to abstract – $ for full-text)
Invited commentary: Laser therapy for genitourinary syndrome of menopause: Emperor’s new clothes or a meaningful advance? – BJOG
Related:
M-A | Carbon dioxide laser vs. vaginal estrogen for genitourinary syndrome of menopause.
Perspective: From vaginal laser treatment to spa breaks – it’s the great menopause gold rush.
M-A | Dual antiplatelet therapy duration after percutaneous coronary intervention in high bleeding risk
8 Feb, 2023 | 12:16h | UTCDual antiplatelet therapy duration after percutaneous coronary intervention in high bleeding risk: a meta-analysis of randomized trials – European Heart Journal (link to abstract – $ for full-text)
Commentary on Twitter
Dual antiplatelet therapy duration after percutaneous coronary intervention in high bleeding risk: a meta-analysis of randomised trials https://t.co/bIX3fAuOEU @escardio #EHJ #ESCYoung #cardiotwitter @ehj_ed @rladeiraslopes pic.twitter.com/WuzOckXpFX
— European Society of Cardiology Journals (@ESC_Journals) December 20, 2022
M-A | Efficacy of treatments for children, adolescents, and young adults with Tourette’s syndrome
8 Feb, 2023 | 12:13h | UTCComparative efficacy, tolerability, and acceptability of pharmacological interventions for the treatment of children, adolescents, and young adults with Tourette’s syndrome: a systematic review and network meta-analysis – The Lancet Child & Adolescent Health (link to abstract – $ for full-text)
Commentary on Twitter
Treatment recommendations are inconsistent for #Tourette syndrome.
New network meta-analysis by @luis_farhat & team shows that #antipsychotics are the most efficacious, while α-2 agonists are also more efficacious than placebohttps://t.co/awYHWUJA3v
— The Lancet Child & Adolescent Health (@LancetChildAdol) December 19, 2022
Machine learning-based marker for coronary artery disease: derivation and validation in two longitudinal cohorts
8 Feb, 2023 | 12:14h | UTCMachine learning-based marker for coronary artery disease: derivation and validation in two longitudinal cohorts – The Lancet (link to abstract – $ for full-text)
News Release: Digital marker for coronary artery disease built by researchers at Mount Sinai
Commentary: Machine learning used to generate a new holistic model for coronary artery disease – News Medical
Commentary from the author on Twitter (thread – click for more)
Christmas came early… my first paper of my postdoc is officially published @TheLancet!! https://t.co/pozEyRKkD0
This was a wild journey with the @DoGenetics lab to build a digital marker for heart disease using AI + electronic health records🫀🤖 Here's why:
1/🧵— Iain S. Forrest, PhD (@IainSForrest) December 21, 2022
Cohort Study | Risk of primary hematologic cancers following incident non-metastatic breast cancer
8 Feb, 2023 | 12:11h | UTC
RCT | Efficacy of a loading dose of IV salbutamol in children with severe acute asthma admitted to a PICU
8 Feb, 2023 | 12:10h | UTC
Cohort Study | Perinatal predictors of clinical instability at birth in late-preterm and term infants
8 Feb, 2023 | 12:09h | UTC
SR | Sodium assessment in neonates, infants, and children
8 Feb, 2023 | 12:01h | UTC
Guideline | Assessment and management of complex fractures
7 Feb, 2023 | 14:19h | UTCFractures (complex): assessment and management – National Institute for Health and Care Excellence
Guideline | Delirium: prevention, diagnosis and management in hospital and long-term care
7 Feb, 2023 | 14:21h | UTC
SR | Calcium and vitamin D supplements do not increase bone mineral density or prevent fractures in premenopausal women
7 Feb, 2023 | 14:18h | UTCCalcium and vitamin D for increasing bone mineral density in premenopausal women – Cochrane Library
Summary: Calcium and vitamin D for improving bone health in healthy premenopausal women – Cochrane Library
SR | The current evidence does not support a role for Vitamin D in the management of asthma
7 Feb, 2023 | 14:16h | UTCVitamin D for the management of asthma – Cochrane Library
Commentary: Vitamin D for asthma: new evidence, new message – Evidently Cochrane
Review | Diagnosis and management of autoimmune hepatitis
7 Feb, 2023 | 14:14h | UTCDiagnosis and management of autoimmune hepatitis – The BMJ
Evaluation of a 12-gene pharmacogenetic panel to prevent adverse drug reactions
7 Feb, 2023 | 14:13h | UTCA 12-gene pharmacogenetic panel to prevent adverse drug reactions: an open-label, multicentre, controlled, cluster-randomised crossover implementation study – The Lancet (link to abstract – $ for full-text)
News Releases:
Matching medication to DNA leads to 30% fewer side effects – University of Liverpool
Genetic analysis can reduce adverse drug reactions by 30 per cent – Karolinska Institutet
Commentary from one of the authors on Twitter
A journey which started in 2016 has led to the publication of the #PREPARE study in @TheLancet today. In this #randomised study, we show that a 12-gene panel can reduce #adverse_effects by 30%. https://t.co/vj7gYzgxyf @CDSS_Liverpool @pandtuol pic.twitter.com/tjgFWDuTQf
— Munir Pirmohamed (@MPUoL) February 3, 2023
Opinion | Let’s do the Cochrane review of physical measures to reduce the spread of viruses
7 Feb, 2023 | 14:11h | UTCOriginal Study: SR | Physical interventions to interrupt or reduce the spread of respiratory viruses
Related: Hospital masking should be optional – Sensible Medicine
RCT | Medial retropharyngeal nodal region sparing radiotherapy vs. standard radiotherapy in patients with nasopharyngeal carcinoma
7 Feb, 2023 | 14:09h | UTC
RCT | Paxlovid did not improve outcomes in hospitalized patients with Covid-19
7 Feb, 2023 | 14:08h | UTC
M-A | Heparin full-dose anticoagulation is beneficial for non-critically ill COVID-19 patients
7 Feb, 2023 | 14:06h | UTCRelated:
Anticoagulants for people hospitalised with COVID‐19 – Cochrane Library
Home dialysis: conclusions from a KDIGO controversies conference
7 Feb, 2023 | 14:03h | UTC
Consensus Paper | Physical therapy for upper cervical instability in patients with symptomatic generalized joint hypermobility
7 Feb, 2023 | 14:01h | UTC
ESPEN guideline on clinical nutrition in inflammatory bowel disease
7 Feb, 2023 | 14:02h | UTCESPEN guideline on Clinical Nutrition in inflammatory bowel disease – Clinical Nutrition
SR | Cognitive stimulation to improve cognitive functioning in people with dementia
7 Feb, 2023 | 13:59h | UTCCognitive stimulation to improve cognitive functioning in people with dementia – Cochrane Library
Summary: Can cognitive stimulation benefit people with dementia? – Cochrane Library
SR | Intravenous immunoglobulin for the treatment of Kawasaki disease
7 Feb, 2023 | 13:58h | UTCIntravenous immunoglobulin for the treatment of Kawasaki disease – Cochrane Library
Summary: Immunoglobulin treatment for Kawasaki disease – Cochrane Library
Related:
Systematic Review: Corticosteroids for the treatment of Kawasaki disease in children.
Cohort Study | Analysis of factors associated with coronary arterial aneurysm regression in patients with Kawasaki disease
7 Feb, 2023 | 13:56h | UTCRelated:
Intravenous immunoglobulin for the treatment of Kawasaki disease – Cochrane Library
Systematic Review: Corticosteroids for the treatment of Kawasaki disease in children.
RCT | Time-restricted eating and exercise training improve HbA1c and body composition in women with overweight/obesity
7 Feb, 2023 | 13:54h | UTC
Commentary on Twitter
Time-restricted eating (TRE) and high-intensity interval training (HIIT) both improve glucose control and reduce fat mass in people w/ obesity.
Combining TRE (<10 hour eating window) with 3 x weekly HIIT enhances these benefits.
🔗:https://t.co/m051O3AUPW pic.twitter.com/6q6mtzDwVB
— Brady Holmer (@B_Holmer) October 4, 2022
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