Evaluation of a 12-gene pharmacogenetic panel to prevent adverse drug reactions

A 12-gene pharmacogenetic panel to prevent adverse drug reactions: an open-label, multicentre, controlled, cluster-randomised crossover implementation study – The Lancet (link to abstract – $ for full-text)

News Releases:

Matching medication to DNA leads to 30% fewer side effects – University of Liverpool

Genetic analysis can reduce adverse drug reactions by 30 per cent – Karolinska Institutet

Commentary from one of the authors on Twitter

A journey which started in 2016 has led to the publication of the #PREPARE study in @TheLancet today. In this #randomised study, we show that a 12-gene panel can reduce #adverse_effects by 30%. https://t.co/vj7gYzgxyf @CDSS_Liverpool @pandtuol pic.twitter.com/tjgFWDuTQf

— Munir Pirmohamed (@MPUoL) February 3, 2023